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European Health Evidence

The European alternative to PubMed

EUVIMED is the European alternative to PubMed: a central, multilingual research platform for medicine, nursing, life sciences and healthcare. It brings together international and European literature sources, study registries, open-access full texts, citations and retraction notices in one search. Unlike pure bibliographic databases, EUVIMED supports the entire research process – from discovery and appraisal with LIVIA and CLARA to traceable evidence synthesis. European in focus, transparent, interoperable and designed for science and healthcare.

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EUVIMED Themenbrowser · Alle Themen · Seite 178

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
07.09.2026journal-article

Frontiers in Medicine

Recurrence of generalized cutaneous lichen planus after switching from PD-1 to PD-L1 in a patient with pre-existing oral lichen planus: a case report

Yuning Zhang, Yali Li, Tao Guo

We present a clinicopathologically documented case of generalized cutaneous lichen planus that recurred after switching from a programmed death 1 (PD-1) inhibitor (camrelizumab) to its ligand PD-L1 inhibitor (atezolizumab) in a patient with pre-existing oral lichen planus. While relapse of induce immune-related adverse events (irAEs) after PD-1/PD-L1 switching has been previously reported, most of these reports described cutaneous manifestations merely as “rash” without detailed dermatological characterization. In …

07.09.2026journal-article

Medicina

Clinical Impact of Fingolimod-Associated Lymphopenia in Multiple Sclerosis: A Real-World Cohort Study

Murat Yeniçeri, Mustafa Can Şenoymak, Süleyman Baş, Hasan Hakan Çoban, Ayşe Gürbüz Yeniçeri, Serkan Demir, Alpaslan Tanoglu

Background and Objectives: Fingolimod, a sphingosine-1-phosphate receptor modulator, is an effective disease-modifying therapy for relapsing forms of multiple sclerosis (MS). Although lymphopenia is a well-recognized pharmacological effect, its clinical significance remains uncertain. This study evaluated the frequency and severity of fingolimod-associated lymphopenia, longitudinal hematological changes and their relationship with clinical outcomes in a real-world MS cohort. Materials and Methods: This retrospectiv …

07.09.2026journal-article

Scientia fructuosa

Conceptualising archival heritage management in Jordan: policy, digitisation, and public access

Ayman ALAMR

This study examines the transformation of archival governance from a traditional protec­tion-oriented paradigm to an integrated mana­gement framework, with a specific focus on the Jordanian context. While archival institutions have historically prioritised the safeguarding and preservation of documentary materials, contem­porary developments in digital technology, gover­nance models, and public expectations necessitate a broader and more strategic approach. A hypothesis is proposed that leads to an integrated model …

07.09.2026journal-article

Journal of Water and Health

Microplastic contamination in the Karnaphuli River, Bangladesh: a case study of exposure pathways in data-scarce tropical river systems

Masuma Wahab, Abdul Hasib Mollah

ABSTRACT Graphical summary of microplastic pollution in the Karnaphuli River. It illustrates sources such as industrial discharge, municipal waste, and urban runoff, transport through water and sediments, ingestion by fish, and human exposure through fish consumption, highlighting a source-to-human pathway. Microplastic (MP) pollution is an emerging environmental concern in the Global South, yet its implications for human exposure remain insufficiently understood. This study presents a systematic literature review …

07.09.2026journal-article

Clinical Oral Investigations

A preliminary antimicrobial investigation of lactobacillus bulgaricus probiotic supernatants as an intracanal medication against mature E. faecalis biofilm in an ex-vivo dentin blocks model

Sherif Heidar, Hayam Y. Hassan, Edgar Schäfer, Shehabeldin Saber

Abstract Aim To provide a preliminary assessment of the antimicrobial potential of Lactobacillus bulgaricus probiotic against mature Enterococcus faecalis biofilm in dentin model under ex-vivo conditions using confocal laser scanning microscopy (CLSM). Methods Lactobacillus bulgaricus and Lactobacillus acidophilus probiotic strains were grown, centrifuged, filtered by syringe filter size 0.45 microns to acquire cell free supernatants (CFS). Lyophilized CFS of each probiotic strain was individually mixed with Poloxa …

07.09.2026journal-article

Scottish Medical Journal

Litigation in obstetrics and gynaecology in the UK National Health Service over a 17-year period: An analysis of the trends, costs and causes

Anoushka Umranikar, Abhinav Tiwari, Bhaskar K Somani

Introduction Obstetrics and Gynaecology (O&G) is one of the most litigious medical specialities. This study aimed to analyse the trends and reasons for litigation claims in O&G within the UK National Health Service (NHS) over a 17-year period. Methods Using data requested from NHS Resolution under the Freedom of Information Act 2000, an analysis was carried out which included the total number and rate of litigation claims in O&G, the number of these claims that were successful (settled or closed), the damages paid …

07.09.2026journal-article

Journal of Psychopharmacology

Psychedelic therapy without durable effects: A review and re-evaluation of controlled studies between 1965 and 1977

Torsten Passie, Michiel van Elk

Common wisdom in the psychedelic literature suggests that early controlled trials of psychedelic therapy were methodologically flawed. In this review we challenge this view and discuss 11 controlled studies that were conducted in the United States and Canada between 1965 and 1977 to evaluate psychedelic (peak) therapy for individuals suffering from alcohol and opioid use disorder and psychoneuroses. We provide a narrative review of the designs, methods, settings, treatment issues and results and show that these stu …

07.09.2026journal-article

Adolescência e Saúde

Internalization of Weight Stigma: Psychological Mechanisms, Health Consequences and Intervention Measures: A Narrative Review

Wong Siew Kin, Bustang Bustang, Yee Cheng Kueh, Garry Kuan

This narrative review systematically examines the psychological mechanisms, health consequences, and intervention measures of internalized weight stigma. By searching the literature in PubMed, PsycINFO, and Web of Science, English empirical studies that included core measurements of internalized weight stigma (WBI, such as WBIS) were included. The review clearly states that weight stigma is the prejudice and discrimination an individual faces due to their weight not conforming to societal ideals, and it can be divi …

07.09.2026journal-article

Wilderness & Environmental Medicine

Breaking Trail in the Backcountry: Mentorship on the Mountain

Sarah Petelinsek, Nikki Champion, Rowan Kelner, Olivia Pearson, Peilu Zhang, Patrick G. Hughes

Introduction This study examines characteristics associated with willingness to mentor among backcountry users. Using survey responses from backcountry users, the study investigated their experiences and assessed differences among those willing to assume different mentorship roles. Methods This study used a cross-sectional, comparative secondary data analysis of an online survey conducted in January-February 2025 in Salt Lake City, Utah, through the Utah Avalanche Center. Results A total of 361 participants were in …

07.09.2026journal-article

Veterinary Sciences

NMR Metabolomics in Veterinary Medicine: From Biomarker Discovery to Clinical Implementation

Alvaro Pérez-Collar, Carlos Velasco, Javier Bezos, Jose Luis Izquierdo-Garcia

Nuclear magnetic resonance (NMR)-based metabolomics has emerged as a robust and reproducible analytical platform for investigating the molecular mechanisms underlying disease and identifying candidate biomarkers with potential clinical relevance. Although initially developed for biomedical research, its application in veterinary medicine has expanded rapidly during the last decade, driven by the growing demand for precision medicine approaches capable of improving disease diagnosis, prognosis and therapeutic monito …

07.09.2026journal-article

Technologies

Design, Fabrication, and Evaluation of a Patient-Derived 3D-Printed Anthropomorphic Breast Phantom for Performance Evaluation of Dual-Energy Subtraction in Contrast-Enhanced Mammography

Adrián Belarra, Irene Hernández-Girón, Peter Homolka, Diego García-Pinto, Margarita Chevalier

An anthropomorphic patient-derived 3D-printed breast phantom (4.8 cm compressed thickness, 12.2% volumetric breast density) was evaluated for image-quality assessment in contrast-enhanced mammography (CEM). It comprises four 1.2 cm plates printed via fused filament fabrication (PLA/ABS). Five replicates of one of the plates (target) containing a glandular-tissue surrogate and four cavities for iodinated disks with same iodine area density per plate (0.2–0.5–0.75–1.0–1.5 mg/cm2) were fabricated. As a reference, a ho …

07.09.2026journal-article

Endodontics Today

Review of aligner materials and their clinical applications: A literature review

K. Liang, A. B. Slabkovskaya, H. Tang

Over the past 30 years, more than 5 million patients worldwide with various dentofacial anomalies have undergone orthodontic treatment using clear aligner therapy. The indications for aligner treatment continue to expand, and their clinical use has steadily increased. Owing to continuous advances in biomaterials, the materials used for aligner fabrication have evolved from conventional polymers to more flexible and highly transparent thermoplastic materials. The rapid development of three-dimensional digital techno …

07.09.2026journal-article

Pacific Rim International Journal of Nursing Research

Perceptions of Dementia Among Urban Older Adults in Southern Thailand: A Qualitative Study

Kanittha Naka, Hathairat Sangchan, Karnsunaphat Balthip, Tusanee Khaw, Wallapa Thakan

Dementia is increasing among older adults globally and in Thailand. However,it is often misunderstood as a normal part of aging, and there is limited evidence exploring older adults’ perspectives on dementia, particularly in urban areas in SouthernThailand. This qualitative descriptive study aimed to describe older adults’perceptions of dementia in an urban context in Southern Thailand and was conducted from June to August 2024. Twenty-four participants were recruited through purposive sampling using the inclusion …

07.09.2026journal-article

BMJ Leader

Eco-affective health as a missing pillar of planetary health leadership

Lucas Murrins Marques

Planetary health leadership increasingly depends on the capacity to sustain engagement, legitimacy and long-term action under accelerating environmental change. While leadership frameworks in planetary health have advanced in addressing governance, systems transformation and sustainability practices, they have largely overlooked a foundational dimension through which environmental change is experienced and acted on: affect. This commentary introduces an eco-affective health-informed leadership perspective, arguing …

07.09.2026journal-article

Journal of Internal Medicine

Snus, nicotine pouches and cardiovascular disease: Evidence, mechanisms, and the challenge of novel nicotine products

Magnus Olsson, Hanne Tønnesen, Jakob Hedberg, Johan Sundström, Eva Nordendahl, Björn Klinge, Michael Fored, Cecilia Magnusson, Daniel Jönsson, Peter Persson, Aron Naimi‐Akbar

Abstract Conventional Swedish snus is used by millions in Scandinavia and increasingly worldwide, yet its cardiovascular effects remain poorly characterized. The emergence of nicotine pouches—commonly referred to as ‘white snus’ in Sweden—that deliver comparable nicotine without tobacco constituents adds complexity to a heterogeneous landscape and raises questions about whether cardiovascular risk follows nicotine exposure regardless of product type. We explore epidemiological and mechanistic evidence on snus and c …

07.09.2026journal-article

British Journal of Clinical Pharmacology

Anti‐HER2 therapy–associated echocardiography‐related cardiac dysfunction and severe outcomes: Comparison of disproportionality and report‐level cluster analyses

Junjie Liu, Yuhan Chen, Yuxuan Jiang, Weixuan Liang, Zhuofeng Wen, Meijun Liu, Ziyang Yang, Haopeng Huang, Fei Chen, Yanling Zhang

Aims Conventional pharmacovigilance identifies drug–event reporting signals but not heterogeneity among anti‐HER2 cardiac dysfunction reports. We benchmarked this association using disproportionality analysis and assessed whether report‐level clustering added information beyond cardiovascular co‐reporting. Methods We analysed OpenVigil/FAERS data. A separate openFDA analysis estimated overall, individual‐drug and drug‐group reporting odds ratios (RORs) and proportional reporting ratios (PRRs). The clustering cohort …

07.09.2026journal-article

Advanced Healthcare Materials

Dual‑Channel Hypoxia Detection Using PET‐Based Water‐Soluble Cyanine Probes to Suppress False Negatives in Image‑Guided Pancreatic Cancer Resection

Huiling Huang, Shihao Jiang, Zhipengjun Zhang, Ye Chen, Zhihua He, Haifeng Ge, Guojiang Mao, Lei Zhou, Hongwen Liu

ABSTRACT Fluorescence‑guided surgery using activatable probes is promising, but single‑channel probes often give false negatives—especially in pancreatic cancer due to tumor heterogeneity and limited imaging depth. Here, we built a universal charge‐switching gated PET platform based on cyanine dyes bearing a meso‐quinolinium moiety. This platform—by decoupling quenching from the recognition group—enabled the construction of two structurally analogous, hypoxia‐activatable near‐infrared (NIR) probes (Cy5‐Ql‐NTR and C …

07.09.2026journal-article

Advanced Healthcare Materials

Hydrogel Microneedle‐Integrated Electrochemical Sensor With Negative‐Potential Readout Toward Wash‐Free and Anti‐Interference Monitoring of miRNAs in Tumor Interstitial Fluid

Xiyue Xie, Kaixiu Fu, Xu Li, Lin Li, Luoli Zhou, Chunhui Zhai, Shenglong Le, Jixi Zhang

ABSTRACT Electrochemical quantification of microRNAs (miRNAs) in tumor interstitial fluid (TIF) may provide complementary molecular information for tumor microenvironment assessment, but analytical accuracy is often limited by extraction‐induced biomarker loss/degradation and background interference from endogenous electroactive metabolites. Herein, a hydrogel microneedle‐integrated electrochemical biosensor is developed as a complementary ex vivo molecular sensing approach for wash‐free and anti‐interference monit …

07.09.2026journal-article

Journal of Health Science and Medical Research

Dosimetric Impact of Deformable Image Registration versus Simple Summation in Multi-Fraction HDR Brachytherapy for Cervical Cancer under Standard Protocol

Chitchaya Suwanraksa, Bheampos Rojkitjanuruk, Tanapat Suwanpan, Korrawit Pruegsanusak

Objective: In high-dose-rate brachytherapy for cervical cancer, cumulative dose is commonly estimated using simple summation (SS) of dose–volume histogram parameters, assuming high-dose regions remain spatially consistent across fractions. Deformable image registration (DIR) offers an alternative approach that accounts for interfractional anatomical variations. This study compared the dosimetric outcomes of SS and DIR under standardized clinical protocols.Material and Methods: This retrospective study included 54 p …

07.09.2026journal-article

Frontiers in Neurology

Bright light therapy for post-stroke sleep disturbances: a systematic review and meta-analysis

Xiaolan Tang, Qiuping Gu, Yang Zhan, Xiaomei Sun, Fengqin Wang, Luchen Pan, Hua Zhao

Objective Sleep disturbances are common after stroke and may adversely affect neurological recovery. Although post-stroke sleep disturbances encompass insomnia symptoms, circadian rhythm sleep–wake disturbances, and sleep-disordered breathing, research has focused predominantly on obstructive sleep apnea. This review evaluated the effects of bright light therapy (BLT), a non-pharmacological intervention that may influence circadian regulation, on sleep outcomes after stroke. Methods Ten electronic databases coverin …

07.09.2026journal-article

BMC Nursing

Educational effectiveness of a Tele-POCUS training program for home care nurses in remote and rural settings

Toru Yamada, Takehiro Miyazaki, Hiroki Nin, Shumpei Yoshino, Shuji Ouchi, Suguru Mabuchi, Takahiro Shinohara, Hiroyuki Ichige, Takuma Kimura, Takeshi Ishida, Masayoshi Hashimoto

Abstract Background In Japan, demand for home care is increasing owing to population aging and rising health care costs. However, timely assessment in remote and rural areas remains challenging because of physician shortages. Tele-POCUS (point-of-care ultrasound) has attracted attention as a potential educational and collaborative approach in home care settings; however, evidence regarding Tele-POCUS-oriented education for home care nurses remains limited. Methods We conducted a pre–post educational study of a Tele …

07.09.2026journal-article

Frontiers in Cell and Developmental Biology

Advances in research on hyperoxia-induced acute lung injury: from pathogenesis to therapy

Yingcong Ren, Wujuan Xie, Kai Qi, Yingying Cai

Hyperoxia-induced acute lung injury (HALI) is a serious complication of excessive oxygen exposure, yet its pathogenesis and treatment remain incompletely understood. A growing body of evidence suggests that HALI results from the interplay of oxidative stress, inflammation, immune dysregulation, organelle dysfunction, alveolar barrier disruption, and regulated cell death. In this review, we summarize recent advances in our understanding of these processes and discuss therapeutic strategies that have been investigate …

07.09.2026journal-article

International Journal of Health Sciences and Research

Prospective Analysis of Functional Outcome of Clavicle Fractures Treated by Plate Osteosynthesis

Ashutosh Yadav, Pushpa ., Brijendra Singh

Background: Clavicle fractures are common injuries of the shoulder girdle, with displaced fractures potentially resulting in malunion, nonunion, and impaired shoulder function when managed conservatively. Plate osteosynthesis provides stable fixation and facilitates early postoperative mobilization. However, assessment of functional recovery over serial follow-up is important for evaluating treatment outcomes. This study evaluated the functional outcome and fracture healing following plate osteosynthesis for displa …

07.09.2026journal-article

Таврійський науковий вісник. Серія: Публічне управління та адміністрування

ЛОБІЮВАННЯ ЯК ІНСТРУМЕНТ ВПЛИВУ НА НАЦІОНАЛЬНУ БЕЗПЕКУ НА МІЖНАРОДНОМУ РІВНІ: ПУБЛІЧНО-УПРАВЛІНСЬКИЙ АСПЕКТ

А. І. Некряч, В. В. Дабіжа, Г. В. Кириченко

Стаття присвячена дослідженню лобіювання як інструменту впливу на національну безпеку на міжнародному рівні у публічно-управлінському аспекті, що передбачає аналіз взаємодії держав, транснаціональних корпорацій, міжнародних організацій, оборонно-промислових структур, експертних мереж і груп інтересів у процесі формування безпекової політики. Актуальність теми зумовлена тим, що в умовах глобалізації лобістська діяльність дедалі частіше виходить за межі національних правових систем і може впливати на міжнародні санкц …