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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Frontiers in Medicine

Exploring the qualities and adaptive professional capabilities required of physicians for disaster response through perspective transformation among physicians in Fukushima, Japan

Megumi Yasuda, Rintaro Imafuku, Kaho Hayakawa, Maham Stanyon, Takuya Saiki

Background The Great East Japan Earthquake and the Fukushima Daiichi Nuclear Power Plant accident confronted health care professionals with profound uncertainty and ethical dilemmas. However, it remains unclear how physicians made sense of these extreme experiences, reconsidered their assumptions, values and professional roles, and came to recognize and embody the qualities and adaptive professional capabilities required for disaster response. Aim Through the narratives of physicians in Fukushima, Japan, this study …

03.09.2026journal-article

REMUNOM

Photodynamic Therapy for Breast Cancer and the Translational Potential of Quantum Dots

José Adriell Ramos dos Passos, Glória Rayane Soares Silva, Maria Clarice de Melo Silva, Maria Luiza Alves dos santos, Maria Clara Lima Siqueira, Luiz Henrique de Oliveira Filho, Stephany Lorena Barbosa das Neves, Ludymila Mimoso de Moura, Karen Loraine Macena Santos

Breast cancer remains one of the leading causes of female mortality worldwide, requiring more selective and less invasive therapeutic approaches. This study aimed to analyze the clinical landscape of Photodynamic Therapy (PDT) in breast cancer and discuss the translational potential of Quantum Dots (QDs) as photosensitive platforms. The methodology consisted of a documentary and exploratory analysis of secondary data from five interventional human studies registered on ClinicalTrials.gov, focusing on phases I and I …

03.09.2026journal-article

Law of Succession

THE PUBLIC LAW STATUS OF A NOTARY AS THE BASIS FOR THE PRESUMPTION OF AUTHENTICITY OF A NOTARIZED WILL

Lilia V. Ovsepyan

The article examines the issues surrounding challenges to notarized wills on the grounds of an alleged defect of the testator's will. Particular attention is paid to the evidentiary value of a notarized will. The paper substantiates the necessity of establishing, within judicial and law enforcement practice, a presumption of reliability of notarized expressions of intent. Special emphasis is placed on the public-law status of the notary as a person ensuring the recording and protection of the testator's last will a …

03.09.2026journal-article

BMC Oral Health

Clinical performance of a giomer-based pit and fissure sealant with and without air-abrasion pretreatment: a 12-month randomized clinical trial

Yomna Sayed Khallaf, Olfat Elsayed Hassanein, Aya Mohamed Adly, Dina Kamal

Abstract Background Pit and fissure sealants are widely used for caries prevention; however, their long-term success depends largely on retention. Giomer-based sealants containing surface pre-reacted glass ionomer fillers offer bioactive properties, yet concerns remain regarding their bonding durability when applied with mild self-etch primers. This randomized clinical trial evaluated the effect of bioactive glass air-abrasion pretreatment on the retention and caries preventive efficacy of a giomer-based sealant in …

03.09.2026journal-article

Frontiers in Imaging

Artificial intelligence in breast cancer imaging: a systematic review of detection, segmentation, explainability, and clinical translation

Iqra Iqbal Khan, Syed Adil Hussain Shah, Alexandra Tsipourakis, Marta Malavolta, Aleesha Aleesha, Syed Baqir Hussain Shah, Mozhdeh Hajiani, Andrea Buccoliero, Konstantinos Panagiotopoulos, Syed Taimoor Hussain Shah, Marco Agostino Deriu

Introduction Breast cancer remains the most commonly diagnosed malignancy in women worldwide, with approximately 2.3 million new cases and 670,000 deaths in 2022. Artificial intelligence (AI) is increasingly being applied across breast imaging for detection, characterization, segmentation, risk stratification, explainability, and clinical translation. Methods This systematic review synthesized 284 eligible peer-reviewed publications published between 2015 and 2025, identified through a PRISMA 2020-compliant search …

03.09.2026journal-article

Healthcare

Nocturnal Pain in Patients with Knee Osteoarthritis: A Single-Center Cross-Sectional Study

Köksal Sarıhan, Erdem Özkaya, Cemil Güner, Ali Yazıcı, Osman Topçu, Ceyhun Yurtsever, Erhan Özdemir

Objectives: The aim of this study was to determine the differences between groups with and without nocturnal pain (NP) in patients with knee osteoarthritis (KOA) in terms of radiographic stage, disease severity, neuropathic pain, central sensitivity, sleep quality, physical activity level, and number of hospital visits. Methods: The study included 150 patients with KOA (101 women, 49 men; mean age 64 years (IQR: 9; range: 40–81)). Kellgren–Lawrence (KL) grading was used for radiographic staging, the Western Ontario …

03.09.2026journal-article

Jurnal Ekonomi Bisnis dan Akuntansi

Analisis Implementasi New Public Management dalam Meningkatkan Kualitas Layanan Metro Jabar Trans

Hasna Septiani, Sri Mulyani

Public transport service quality is an important indicator of the successful implementation of New Public Management (NPM) in the public transport sector. Metro Jabar Trans (MJT), a Bus Rapid Transit (BRT) system managed by the West Java Provincial Government through a Buy The Service (BTS) partnership scheme, faces operational challenges such as low load factors, longer-than-standard bus headways, and limited bus stop infrastructure despite significant government subsidies. This study aims to analyze the implement …

03.09.2026journal-article

Health Affairs Scholar

Cross-Country Differences in Household Healthcare Spending

Irene Papanicolas, Jonathan Cylus, Maecey Niksch, Luca Lorenzoni

Abstract Introduction Health systems face financial pressures as populations age and economic growth slows, with implications for who pays for health care and for what drives expenditure growth. Methods We examined changes in outpatient and pharmaceutical care financing across OECD countries from 2000 to 2023. Results While overall health spending growth slowed across countries after the Great Recession, household spending grew modestly everywhere, averaging about half a percentage point growth annually. The United …

03.09.2026journal-article

ISPRS International Journal of Geo-Information

Scale-Dependent Spatial Clustering of Hospital Operational Performance and Patient Safety Outcomes in East Java, Indonesia: A Spatial Autocorrelation Analysis

Muhammad Kamran, Inge Dhamanti, Shumaila Ismail

Understanding variations in hospital performance and patient safety is critical for improving health system efficiency, particularly in decentralized healthcare systems such as that of Indonesia. While geographic disparities in health outcomes are often emphasized in research, the relative contribution of spatial patterns remains underexplored. The aim of this study was to identify and visualize spatial clustering of hospital performance and mortality-oriented patient safety. Data from 428 hospitals in East Java, I …

03.09.2026journal-article

Rambam Maimonides Medical Journal

Fetal Pain: Neurobiology, Clinical Practice, and Compassionate Care—A Narrative Review

Omri Dominsky, Ido Solt

Background: Whether a fetus can experience pain remains scientifically and clinically contested, particularly as invasive fetal procedures become more common. Objectives: To review fetal nociceptive development, the evidence and uncertainties relevant to pain perception, and the clinical rationale for fetal analgesia during invasive procedures. Methods: We performed a targeted narrative search of PubMed/MEDLINE, Google Scholar, the Cochrane Library, reference lists, and professional society websites. The final synt …

03.09.2026journal-article

Eastern Mediterranean Health Journal

Diagnostic performance of urine-based rapid diagnostic malaria tests in Pakistan

Rashid Ali, Muhammad Asrar, Salma Sultana, Amna Sajjad

Background: Urine-based rapid diagnostic tests offer a non-invasive alternative for malaria diagnosis; however, their use has not been evaluated in Faisalabad, Pakistan. Aim: To assess the diagnostic accuracy of a urine-based rapid diagnostic test for detecting Plasmodium vivax and Plasmodium falciparum infections in Faisalabad, Pakistan. Methods: From January 2023 to December 2024, we collected and analysed laboratory samples from 360 febrile patients aged ≥5 years, with clinical symptoms suggestive of malaria, at …

03.09.2026journal-article

BMC Health Services Research

Balancing needs and resources in mental health care through the lens of public and provider perspectives

Wahiba Abu-Ras, Leena Babiker Idris, Mai Al-Quraini, Shahira Amin

Abstract Background Telemental health care (TMHC) may offer convenient and private pathways to mental health support, but its feasibility and acceptability depend on the cultural, structural, and operational context in which it is delivered. This qualitative study examined how members of the general population and mental health professionals perceived the barriers and opportunities associated with TMHC in Qatar. Methods This qualitative study employed semi-structured interviews with 62 participants, comprising memb …

03.09.2026journal-article

Frontiers in Medicine

Impact of antiplatelet therapy on erectile dysfunction following percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction

Joongwon Choi, Chung Un Lee, Hyun Woong Park, Jung Hoon Kim, Yong Seong Lee, Jong-Hwa Ahn, Jin Sin Koh, Min Gyu Kang, Weon Kim, Udaya S. Tantry, Paul A. Gurbel, Jin-Yong Hwang, Young-Hoon Jeong

Background: Acute myocardial infarction (AMI) is strongly associated with erectile dysfunction (ED). This study evaluated the association between P2Y 12 receptor inhibitor type and ED, and factors associated with moderate-to-severe ED in high-risk patients with AMI. Methods The HEALING-AMI trial randomized patients with naïve ST-segment elevation myocardial infarction (STEMI) to dual antiplatelet therapy (DAPT) with either ticagrelor or clopidogrel. This substudy included 59 male patients who completed 6 months of …

03.09.2026journal-article

BMC Medical Education

A longitudinal core curriculum to strengthen interprofessional competencies in German undergraduate nursing education: a mixed methods study

Tanja Lehnen, Frederike Lueth, Lisa Wolter, Jutta Busch, Laura Püschel, Miriam Leimer, Anne C. Rahn, Katrin Balzer, Wolfgang von Gahlen-Hoops

Abstract Aim Interprofessional education is considered an important strategy for improving interprofessional collaboration in healthcare practice. The aim of the interEdu project was to develop a longitudinal core curriculum to strengthen interprofessional competencies in undergraduate nursing education. Methods The study was conducted using a mixed methods design with qualitative and standardized interviews and evidence syntheses. The results were triangulated via joint displays and were discussed in an expert wor …

03.09.2026journal-article

Frontiers in Oncology

Bibliometric and clinical trial landscape of hepatoblastoma (2000–2024): a multi-database analysis of global research

Xu Li, Junyi Lou, Xiaoyu Li, Shibo Tang, Shuang Li, Zining Luo, Jiebin Xie

Background Hepatoblastoma (HB) is the most common childhood liver malignancy, yet its research trajectory and trial landscape remain uncharacterized. Methods We analyzed 219 trials from 16 international registries and 2,635 PubMed publications (2005–2024) using joinpoint regression, Gini coefficient, and diversity indices. Results Trial activity peaked in 2013 and 2016, driven by risk-stratified protocols and the emergence of targeted therapies. Phase III/IV trials were scarce. Cisplatin dominated drug utilization, …

03.09.2026journal-article

Frontiers in Public Health

Chile’s 2021 constitutional neurorights amendment: a cognitive sovereignty preliminary conceptual framework for non-traditional security analysis

Karolina Zhukoff

Chile’s 2021 constitutional amendment on neurorights, the first such provision anywhere in the world, is widely characterized in the literature as a rushed, conceptually underdeveloped instance of liberal rights extension. This article proposes an alternative framing. Examined through the intersecting lenses of non-traditional security (NTS) theory, international law, and the political history of post-colonial statehood and technological dependency, this article challenges this view and proposes that the 2021 const …

03.09.2026journal-article

International Journal of Science, Strategic Management and Technology

Impact of Coal Mining on Groundwater Quality and Human Health: A Case Study

Swastik Choubay, Ram Chandra Chaurasia

Groundwater resources in coal mining regions are increasingly threatened by intensive mining activities that alter natural hydrogeochemical conditions and facilitate the mobilization of heavy metals into aquifer systems. This study evaluates the groundwater quality and associated human health risks in the Sohagpur Coalfield, Shahdol District, Madhya Pradesh, India, a major coal-producing region of the Son Valley Basin. The assessment integrates hydrogeological perspectives with physicochemical and heavy metal analy …

03.09.2026journal-article

Journal of Racial and Ethnic Health Disparities

Intersectional Barriers to Protection: Service Providers’ Perspectives on Supporting Black, Latino, and Immigrant Male Victims of Female-perpetrated Intimate Partner Violence

Lyric N. Russo, Chiara Sabina, Kerry A. Lee, Jennifer L. Mezzapelle, Denise A. Hines, Emily M. Douglas

Abstract Aim This study examined service providers’ perspectives on how race, ethnicity, and immigration status shape help-seeking experiences and institutional responses for Black, Latino, and immigrant male victims of female-perpetrated intimate partner violence (IPV). Method Semi-structured Zoom interviews were conducted with 10 service providers, primarily from the United States (with one provider each from Canada and Ireland), who work with male victims of female-perpetrated IPV. Participants included 5 attorn …

03.09.2026journal-article

Annals of Thoracic Medicine

Prevalence and prognostic significance of obstructive sleep apnea in patients with idiopathic pulmonary fibrosis: A prospective cohort study

Hasibe Çigdem Erten, Sevda Sener Cömert, Gülten Aktin Güngör, Elif Yilmaz, Ayse Havan, Nesrin Kiral

ABSTRACT BACKGROUND: Obstructive sleep apnea (OSA) is a recognized comorbidity in idiopathic pulmonary fibrosis (IPF); however, its true prevalence remains uncertain, and its prognostic implications have not been fully elucidated. This study aimed to determine the prevalence of and risk factors for OSA in patients with IPF and to evaluate its impact on disease progression. METHODS: This prospective study enrolled 50 patients with IPF followed at a tertiary care center. All patients underwent polysomnography (PSG), …

03.09.2026journal-article

Problems of Forensic Sciences

Fatal gunshot wounds from black powder weapons, examined at the Kraków Forensic Medicine Institute

Zuzanna Kozłowska, Anna Stanaszek, Natalia Zabawa, Ewa Baran, Agnieszka Moskal, Anna Sojka, Tomasz Konopka

Black powder weapons include firearms manufactured before 1885 and their modern replicas. They use black powder instead of smokeless one and in Poland they are completely legal to possess and carry, even without a permit. The study aimed to examine cases of fatalities caused by black powder weapons recorded at the Department of Forensic Medicine in Kraków and compare them to deaths resulting from conventional firearms. A review of autopsy reports and photographic documentation from January 2012 to December 2025 was …

03.09.2026journal-article

Socio-Ecological Practice Research

Engendering human and nonhuman health: a critical socio-ecological approach to zoonotic disease

Jasmine Therese Arcilla, Jacob Bull, Sarah Dickin

Abstract Addressing zoonotic diseases often calls for collaborative efforts across health and agriculture sectors to find ways to control or eliminate these pathogens. However, existing techno-scientific and biomedical interventions frequently fall short given the siloed nature of their knowledge and implementation, compounded by the overall lack of consideration for socio-ecological factors and interactions that contribute to disease transmission. Moreover, even when established socio-ecological models are applied …

03.09.2026journal-article

Maternal-Fetal Medicine

Global, Regional, and National Burden of Neural Tube Defects and Digestive Congenital Anomalies in Newborns, 1990–2021, With Projections to 2050: Results From the 2021 Global Burden of Disease Study

Hong Zeng, Hao Chen, Qiao He, Danqing Zhao

Abstract Objective: To provide global, regional, and national estimates of disability-adjusted life years (DALYs) for neural tube defects (NTDs) and digestive congenital anomalies (DCAs) from 1990 to 2021, with projections to 2050, to inform resource allocation and identify high-burden populations. Methods: Using data from the Global Burden of Disease 2021 study, we analyzed the burden of NTDs and DCAs through descriptive and trend analyses. Age-standardized rates were examined by sex, age, region, and socio-demogr …

03.09.2026journal-article

Asia-Pacific Journal of Clinical Oncology

Comprehensive Genomic Profiling Timeliness Beyond Laboratory Turnaround Time: A Patient‐Facing Pathway Analysis

Shinya Kajiura, Naohiko Nakamura, Ryuji Hayashi

ABSTRACT Aim We evaluated the timeliness of the patient‐facing comprehensive genomic profiling (CGP) pathway by separating laboratory and post‐laboratory intervals within an expert panel‐mediated process, using direct disclosure of results to patients as the endpoint. Methods This single‐center retrospective study included adult CGP test episodes performed under government‐funded cancer genomic medicine at a Japanese university hospital between October 2019 and November 2025. The primary outcome was patient‐centere …

03.09.2026journal-article

Journal of Addiction Medicine

Outpatient Direct Initiation of Injectable Buprenorphine From Methadone: A Case Series

Daniel Liauw, Ram Sundaresh, Dinah Applewhite, Jessica R. Gray, Laura Kehoe, Evangeline Kennedy, Susan Regan, Sarah Wakeman

Objectives: Published protocols for directly initiating injectable buprenorphine from full opioid agonists (“direct-to-inject” or DTI) have largely described patients with active or recent fentanyl use. Among patients with opioid use disorder (OUD) in remission, transitioning from methadone to buprenorphine with sublingual buprenorphine can be challenging. Published experience utilizing DTI buprenorphine from methadone is limited. Methods: In this retrospective cohort study, we identified 15 patients across an acad …