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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Asia-Pacific Journal of Clinical Oncology

Comprehensive Genomic Profiling Timeliness Beyond Laboratory Turnaround Time: A Patient‐Facing Pathway Analysis

Shinya Kajiura, Naohiko Nakamura, Ryuji Hayashi

ABSTRACT Aim We evaluated the timeliness of the patient‐facing comprehensive genomic profiling (CGP) pathway by separating laboratory and post‐laboratory intervals within an expert panel‐mediated process, using direct disclosure of results to patients as the endpoint. Methods This single‐center retrospective study included adult CGP test episodes performed under government‐funded cancer genomic medicine at a Japanese university hospital between October 2019 and November 2025. The primary outcome was patient‐centere …

03.09.2026journal-article

Journal of Addiction Medicine

Outpatient Direct Initiation of Injectable Buprenorphine From Methadone: A Case Series

Daniel Liauw, Ram Sundaresh, Dinah Applewhite, Jessica R. Gray, Laura Kehoe, Evangeline Kennedy, Susan Regan, Sarah Wakeman

Objectives: Published protocols for directly initiating injectable buprenorphine from full opioid agonists (“direct-to-inject” or DTI) have largely described patients with active or recent fentanyl use. Among patients with opioid use disorder (OUD) in remission, transitioning from methadone to buprenorphine with sublingual buprenorphine can be challenging. Published experience utilizing DTI buprenorphine from methadone is limited. Methods: In this retrospective cohort study, we identified 15 patients across an acad …

03.09.2026journal-article

Oxford Open Digital Health

Leveraging Digital Pathology to Enhance Breast Cancer Diagnosis in Low-Resource Settings: A Cross-Sectional Study of Major Histopathology Laboratories in Uganda

Agnes Rwashana Semwanga, James Serubugo, Vincent Micheal Kiberu, Hawa Nalwoga, Evelyn Kigozi Kahiigi, Nazarius Mbona Tumwesigye, Sam Kalungi

ABSTRACT Background Breast cancer remains a leading cause of morbidity and mortality among Ugandan women, particularly in rural areas where pathology infrastructure and specialist access are limited. This study aimed to improve diagnostic efficiency and accuracy by digitizing breast cancer slides and implementing a web-based histopathology system to support remote diagnostics. Methods A total of 100 glass slides from core breast biopsy samples were digitized using an Aperio AT2 slide scanner. A web-based Breast His …

03.09.2026journal-article

PLOS Digital Health

Socioeconomic determinants of malaria in Ugandan children: An interpretable machine learning approach for public health policy

Cleiane Gonçalves Oliveira, Marcos Flávio S. V. D’Angelo, Matheus P. Libório, Marcelo Perim Baldo, Hasheem Mannan

Malaria remains a critical global health crisis, placing a disproportionate burden on children under five in Uganda. To transition from broad surveillance to targeted intervention, this study applies interpretable machine learning to identify key socioeconomic predictors of malaria using the 2018–2019 Uganda Malaria Indicator Survey. By employing Random Forests for feature selection and Decision Trees for classification, we addressed the inherent class imbalance using robust metrics such as the F2-score, Matthews C …

03.09.2026journal-article

Journal of Palliative Care

Respecting Spinal Cord Injury Patient Autonomy in the Context of Terminal Extubation

Rainy B.S. Wortelboer, Lauren Hall, Fareea Khaliq

Terminal extubation, or palliative or compassionate extubation, is a legally and ethically accepted practice in the United States where mechanical ventilation is withdrawn when ongoing life-sustaining treatment no longer aligns with a patient's stated goals of care. Nearly 42% of intensive care unit deaths involve withdrawal of such measures. Despite its legal acceptance, terminal extubation remains a nuanced decision, particularly in patients with spinal cord injury (SCI). Approximately 18,000 new traumatic SCIs o …

03.09.2026journal-article

INTERNATIONAL JOURNAL OF HEALTH AND PHARMACEUTICAL RESEARCH

Factors Determining Sleep Patterns Among Individuals

Awe Joseph Kolawole

Sleep is a vital physiological process essential for physical repair, cognitive function, and emotional balance. But even so, poor sleep has turned into a major global health crisis, with high rates seen everywhere from international cities to our local communities. Poor sleep quality is increasingly recognized as a major risk factor for chronic conditions, including heart disease, diabetes, obesity, and depression. This seminar looks closely at what determines sleep patterns for students and the general public, th …

03.09.2026journal-article

RECIE. Revista Electrónica Científica de Investigación Educativa

Alfabetización digital autopercibida y factores asociados en estudiantes de escuelas secundarias públicas de Yucatán, México

Alfredo Zapata González, William René Reyes Cabrera, Sergio Humberto Quiñonez Pech

This study aimed to analyze perceived digital literacy among students attending public secondary schools in Yucatán, Mexico. A quantitative, cross-sectional, observational, and correlational design was employed. The study included a non-probability convenience sample of 501 students aged 12 to 17 years from ten urban and rural schools. Data were collected online using a 39-item self-report questionnaire covering nine dimensions of digital literacy. Overall, 80% of participants identified school assignments as their …

03.09.2026journal-article

Journal of Palliative Medicine

Threatened Identity: Self Psychology Informed Communication for Serious Illness Care

Daniel Shalev, Indrany Datta-Barua, Leah B. Rosenberg, Keri O. Brenner, Theodore Scheel, Danielle Chammas

Serious illness threatens both the body and the self: the coherent, continuous sense of who one is, from bodily integrity to psychosocial identity. When illness disrupts identity and patients confront mortality and dependence, a range of responses may follow, including behaviors such as relentless demands, devaluation of clinicians, insistence on additional treatment, or rage at perceived care failures. These presentations are often labeled “narcissistic,” yet such a formulation can foreclose clinical understanding …

03.09.2026journal-article

Journal Archives of Health

Associação entre características clínicas e cirúrgicas e complicações operatórias em pacientes submetidas a histerectomia por causas benignas em um hospital de referência: um estudo transversal características clínicas, cirúrgicas e complicações operatóri

Ana Beatriz de Oliveira Torres, Aurélio Antônio Ribeiro Costa, Francilberto Dyego de Souza, Caroline Oliveira Mendes, Iasmin Maria Oliveira Castro, Henrique Assis da Mota Barbosa

Objetivo: Analisar características clínicas das indicações da histerectomia, características cirúrgicas e complicações operatórias. Metodologia: Estudo transversal, analítico, com pacientes submetidas a histerectomia por doença benigna, de janeiro a agosto de 2022, no Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife/PE. Foram incluídas 105 pacientes e estudadas variáveis biológicas, sociodemográficas, clínicas e cirúrgicas. O valor de p

03.09.2026journal-article

Brazilian Journal of Implantology and Health Sciences

Persistência tecidual e complicações tardias associadas a preenchedores à base de ácido hialurônico: uma revisão integrativa

Pedro Henrique Alves, Régis Rodrigues Santana, Katiulcy Carvalho Oliveira, Ivan Silveira de Avelar, Luciene Apolinário de Araújo, Juliana Pires Ribeiro, Álvaro Paulo Silva Souza, Marcelo Carneiro dos Santos, Brenda Kaoanna Borges de Souza, Luiz Gustavo Nunes de Lima, Juliana Dias Medeiros, Camilla Cristina Almeida Silva

Introdução: Os preenchedores à base de ácido hialurônico (AH) são amplamente utilizados em procedimentos estéticos e, embora sejam considerados biodegradáveis, evidências recentes têm demonstrado que o material pode permanecer nos tecidos por períodos superiores aos tradicionalmente esperados, levantando questões acerca de seu comportamento e de possíveis complicações em longo prazo. Objetivo: Analisar as evidências disponíveis acerca da persistência prolongada e da presença de resíduos teciduais de preenchedores à …

03.09.2026journal-article

Migration LAW

On Some Problems of Public Administration and Protection of the Rights of Migrant Women in Russia and Foreign Countries

Miroslava I. Petrovskaya

The article is devoted to the problems of public administration in the sphere of migration policy both in the context of the formation of a differentiated management approach to different categories of migrants and the elimination of problems of protecting the rights of women migrants based on the analysis of the experience of Russia and foreign countries. The existing problems are related to the vulnerable social position of women migrants, problems of social adaptation and integration, and the insufficient effect …

03.09.2026journal-article

Archives of Current Research International

Health Issues of Elderly Women in India: A Gender-responsive Critical Review of Physical, Nutritional, Mental and Social Health

Swati Sucharita, Tapaswini Binakar, Subhashree Jagdev

India is ageing rapidly, and the older population is becoming progressively more female. Women aged 60 years and above outnumber men, survive longer at every advanced age, and are far more likely to be widowed, materially dependent and socially isolated. Their health, nonetheless, is usually examined either as an undifferentiated component of geriatric epidemiology or as a residual category within women’s health research that remains organised around the reproductive years. This critical narrative review evaluates …

03.09.2026journal-article

Frontiers in Medicine

Impact of antibody-mediated rejection detected on one-year protocol biopsies on long-term kidney allograft survival

Galina Severova, Vlatko Karanfilovski, Lada Trajceska, Irena Rambabova-Bushljetik, Pavlina Dzekova-Vidimliski, Igor G. Nikolov, Nikola Gjorgjievski, Gordana Petrushevska, Slavica Kostadinova-Kunovska, Goce Spasovski, Ninoslav Ivanovski

Introduction Kidney transplantation undoubtedly remains the best way of treatment for end-stage chronic kidney disease. Enormous success has been achieved in improving short-term graft survival, but long-term graft survival has presented a great challenge, especially from an immunological perspective. This study aimed to evaluate the impact of antibody-mediated rejection (ABMR) detected on one-year protocol graft biopsies in kidney transplant recipients with stable graft function on 10-year death-censored graft sur …

03.09.2026journal-article

Frontiers in Medicine

A comparative study on mental health outcomes in patients with rheumatoid arthritis and knee osteoarthritis

Meng Jia, Shuang Wang, Chenxi Yu, Ping Li

Objective This study aimed to analyze the current status and differences in mental health levels between patients with rheumatoid arthritis (RA) and knee osteoarthritis (OA) to provide a reference for clinical nursing interventions. Methods Using convenience sampling, patients with knee osteoarthritis and rheumatoid arthritis who were hospitalized at a tertiary first-class hospital in Shandong Province from May to August 2025 were selected for a cross-sectional survey, and the differences in mental health levels be …

03.09.2026journal-article

American Journal of Surgical Pathology

Expanding the Morphologic, Clinical, and Molecular Spectrum of Succinate Dehydrogenase A (SDHA)-Deficient Renal Cell Carcinoma

Shivani Kandukuri, Anandi Lobo, Harrison Tsai, Manju Aron, Shilpy Jha, Michelle S. Hirsch, Sambit Mohanty

Succinate dehydrogenase (SDH)-deficient renal cell carcinoma (RCC) is defined by mutations in SDH subunits (A, B, C, or D) and is associated with hereditary paraganglioma-pheochromocytoma syndrome and gastrointestinal stromal tumors (GISTs) in some patients. This multi-institutional study analyzed 5 SDHA-deficient RCCs using morphology, immunohistochemistry (IHC), and next-generation sequencing (NGS). Patients had a median age of 40 years with male predominance (4:1). Initially, tumors were diagnosed as SDHA-defici …

03.09.2026journal-article

Journal of Integrative and Complementary Medicine

Bounded Integration: The Regulation of Traditional and Complementary Medicine in Türkiye

Ayşe Polat

Introduction: This study examines Türkiye’s recent policies on traditional and complementary medicine (T&CM), focusing on how centralized governance has expanded and regulated T&CM while maintaining it within biomedical standards. It analyzes how the state-led integration proceeds through control, standardization, and oversight, generating both formal incorporation and persistent frictions. Methods: The study is based primarily on qualitative content analysis of official Ministry of Health materials, including laws …

03.09.2026journal-article

ACM Transactions on Computing for Healthcare

SpineXR-VQA: A Clinically-Validated Visual Question Answering Dataset for Spine X-Rays

Deepali Mishra, Sorayouth Chumnanvej, Vikas Trivedi, Ashutosh Modi, Chaklam Silpasuwanchai

Recent progress in Medical Visual Question Answering (VQA) has significantly aided clinical decision-making across various domains such as pneumonia, oncology, and neurology. However, spinal and musculoskeletal ailments remain critically underexplored. The development of reliable VQA models for spinal imaging is currently hindered by a lack of datasets and evaluation protocols that do not reflect the descriptive, diagnostic interpretations used in clinical practice. In this resource paper, we introduce SpineXR-VQA …

03.09.2026journal-article

Animals

Effects of Single-Cell Protein Derived from Ralstonia eutropha on Growth Performance, Meat Quality, Antioxidant Capacity, and Intestinal Health in Broilers

Xiaoyao Duan, Minglu Guo, Zhiyong Rao, Wei Zhang, Zhixiang Wang, Yongpeng Guo

This study aims to evaluate the feasibility of substituting soybean meal with single-cell protein derived from Ralstonia eutropha H16 (SCP-H16) in broiler diets, with a specific emphasis on its impact on growth performance, meat quality, biochemical parameters, antioxidant capacity, and intestinal health. A total of 540 one-day-old Arbor Acres (AA) male broiler chicks were randomly allocated to five treatment groups, each comprising six replicates of 18 chicks. The control group (CON) was provided with a corn-soybe …

03.09.2026journal-article

Journal of Hospital Medicine

National trends in pathogen‐specific diagnoses and outcomes among hospitalizations for infectious diarrhea

David Wong Arias, Spencer R. Goble, Mauricio Torrealba

Abstract Background The diagnostic evaluation of infectious diarrhea has evolved with increasing adoption of multiplex gastrointestinal nucleic acid amplification tests and changing diagnostic strategies for Clostridioides difficile . Objectives We aimed to assess changes in inpatient pathogen‐specific documentation rates and clinical outcomes on a national level. Methods We performed a retrospective cross‐sectional study using the National Inpatient Sample from 2016 to 2023. Adult hospitalizations with a primary d …

03.09.2026journal-article

Journal of Hospital Medicine

Reducing inpatient falls with a mobility‐first, multidisciplinary intervention at a VA Medical Center

Ryan Duffy, Padideh Imenikashani, Tymeeka Davis, Steven Fairbanks, Folake Ogunmola, Laura Previll, Brian Schneider

Abstract Inpatient falls are a common and preventable source of harm among hospitalized patients. At a Veterans Health Affairs medical center, we implemented a mobility‐first, multidisciplinary intervention using sequential Plan‐Do‐Study‐Act cycles, including redesigned activity orders to “mobilize unless contraindicated,” physical therapist‐led education, and interdisciplinary fall huddles with rapid feedback. Over 18 months, total falls decreased by 34%, from 7.6 to 5.0 per 1000 bed‐days, and injurious falls decr …

03.09.2026journal-article

Journal of Imaging Informatics in Medicine

Long-PVSUNet: A Longitudinal Deep Learning Framework for Count-Oriented Perivascular Space Segmentation in Brain MRI

Shizuka Hayashi, Lei Fan, Jiyang Jiang, Yang Song, Dadong Wang, Henry Brodaty, Perminder S. Sachdev, Wei Wen

Abstract Enlarged perivascular spaces (ePVS) are small, sparse MRI-visible markers of cerebral small vessel disease and brain ageing. Their size, low contrast, and severe foreground–background imbalance make automated segmentation challenging. Existing methods are mainly cross-sectional and do not model temporal consistency, limiting their utility for tracking longitudinal change. We developed Long-PVSUNet, a two-timepoint framework for count-oriented ePVS segmentation on paired baseline/follow-up T1-weighted and F …

03.09.2026journal-article

Frontiers in Public Health

Mapping vocal health risk for active vocal users across European urban soundscapes: a computational framework with exploratory empirical evaluation

Yuwen Sun

Urban soundscape assessments focus on the listener—the person who hears an environment—while largely overlooking the person who must produce sound within it. However, speaking or singing in noisy settings imposes substantial physiological demands due to Lombard effect, which causes vocal intensity to increase as ambient noise raises. In this study, we present a computational framework that integrates the Lombard effect, subglottal pressure estimation, and signal-to-noise ratio (SNR) to translate urban noise levels …

03.09.2026journal-article

Journal of Medicine and Health Research

Psychiatric Morbidity among Fresher Medical Students in a Nigerian Tertiary Institution: A Mixed-Methods Study

Adeoye Oyewole, Adedotun Oyewole, Samson Ojedokun, Chukwunonso Ndulue

Background: The transition into medical school represents a major developmental, academic, and psychosocial challenge for young adults. These challenges may be particularly significant among freshers. The study aimed to determine the prevalence and predictors of psychiatric morbidity among freshers in the medical school of a public university in Nigeria. Methods: A convergent mixed-methods design was used for the study. The quantitative component involved a cross-sectional survey of first-year medical students usin …

03.09.2026journal-article

Frontiers in Medicine

Syphilis causing elevation of anti-CCP: a case report of medical mimicry

Tara Subrahmanyan, Ashley Martinez, Justin Baik, Matthew Kelly

Introduction Infection with Treponema pallidum, or syphilis, is often called the “Great Imitator” because of its propensity for atypical presentations and non-specific symptoms. In addition, syphilis has been shown to create false-positive results for common tests, including Lyme disease, HIV, and multiple autoimmune conditions. One that has not been documented is anti-cyclic citrullinated peptide (anti-CCP). Anti-CCP is a highly specific test for Rheumatoid Arthritis. However, in this case, syphilis led to false-e …