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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Frontiers in Health Services

Patient misidentification and data integrity risks in ultrasound imaging: a case report using multi-framework incident analysis

Benedicta Osei-Donkor, Abdallah Hassoun, Md Shafiqur Rahman Jabin

Background Digital imaging workflows depend on accurate scheduling, patient identity reconciliation, and reliable metadata continuity to ensure safe image storage and retrieval. Disruptions in these processes may not directly affect image acquisition but can delay access to imaging information and pose significant patient safety risks. Objective To examine a recurrent ultrasound workflow failure that compromised downstream image availability and to identify practical strategies for preventing recurrence. Methods A …

03.09.2026journal-article

Frontiers in Medicine

Global trends and thematic clusters in healthcare professional education, medical errors, and patient safety: a bibliometric analysis, 2000–2026

Birgit Hladschik-Kermer, Olena Litvinova, Michel-Edwar Mickael, Maima Matin, Ahmed Fatimi, Anass Belbachir, Mairim Russo Serafini, Maria Kletecka-Pulker, Atanas G. Atanasov, Thomas Wochele-Thoma

Background In the context of the active implementation of the World Health Organization’s Global Patient Safety Action Plan, there is a growing need for a comprehensive synthesis of scientific evidence reflecting the development of research in the field of healthcare professional education. Objective This study aims to conduct a bibliometric analysis of scientific publications addressing the relationship between healthcare professional education, medical errors, and patient safety over the period 2000–2026, based o …

03.09.2026journal-article

Frontiers in Dental Medicine

Curcumin as an adjunct in periodontal therapy: local effects, delivery systems, and clinical perspectives

Ana Carolina Aparecida Rivas, Mario Taba, Paola Gomes Souza

Curcumin, the active polyphenol in turmeric (Curcuma longa), is well-known for its anti-inflammatory, antioxidant, and antimicrobial properties, making it a promising therapeutic agent for a range of diseases, including neuroinflammatory conditions and periodontal disease. Periodontitis, a prevalent oral disease, is associated with chronic inflammation and bacterial infection. Curcumin has demonstrated antibacterial effects against periodontal pathogens such as Aggregatibacter actinomycetemcomitans, Porphyromonas g …

03.09.2026journal-article

Frontiers in Medicine

Time-Series modeling for predicting mortality risk in intensive care unit patients with pulmonary inflammation

Yihai Zhai, Ruixin Xu, Haisu Lu, Siying Lv, Liqin Mo

Objective This study aims to evaluate dynamic changes in pneumonia-related mortality risk among ICU patients using time-series models and develop interpretable predictive models for early mortality assessment. Methods Data were obtained from the MIMIC-IV and eICU Collaborative Research Database. The MIMIC-IV cohort was split into training and testing sets (7:3 ratio), with external validation conducted using the eICU cohort. Missing data were handled using forward filling and multiple imputation. LSTM was used to e …

03.09.2026journal-article

Frontiers in Medicine

Design, implementation, and evaluation of a programmatic assessment model in an emergency medicine residency: a mixed-methods study

İbrahim Ulaş Özturan, Dilek Kitapcioglu, Prattama Santoso Utomo, Cansu Alyesil Ozturan, Nurettin Özgür Doğan, Elif Yaka, Serkan Yılmaz, Murat Pekdemir, Levent Altıntaş

Background Programmatic assessment (PA) is widely endorsed in postgraduate medical education, but empirical accounts of real-world implementation in emergency medicine (EM) remain limited and are concentrated in North American settings. We piloted and evaluated the design, implementation, and outcomes of a PA model in an EM residency at a high-volume tertiary care center in Türkiye. Methods A mixed-methods study was conducted over an eight-month pilot (November 2024–June 2025). Program design and evaluation followe …

03.09.2026journal-article

Frontiers in Oncology

Analysis of clinical features and outcomes in a Chinese cohort with ALK fusion across pan-cancer: a retrospective study

Meng Zhang, Yi Feng, Xue Du, Changda Qu, Meizhu Meng, Meiying Ye, Min Liang, Ziran Yang, Wenjuan Gong, Xingyu Ma, Jialiang Guo, Wenmei Li, Shuqin Jia

Background ALK fusions are validated oncogenic drivers, yet their molecular heterogeneity and therapeutic implications remain poorly characterized. This study defined the landscape of ALK fusion partners, EML4-ALK variants, and co-mutations and their impact on treatment responses in a large Chinese pan-cancer cohort. Methods We retrospectively analyzed 16,335 consecutive pan-cancer patients via next-generation sequencing to identify ALK fusions. Clinical characteristics, fusion partners, co-mutations, and treatment …

03.09.2026journal-article

Sage Sphere International Journal

Cirugía laparoscópica versus cirugía robótica en la resección de tumores hepáticos: resultados y beneficios clínicos

Joel Sebastian Chango Yosa, Kelvin Alejandro Torres Quezada, Mario Gabriel Salas Martínez, Dana Isabel Morales Figueroa, Alonso Patricio Espinoza Ayala

Introducción: La resección hepática constituye el tratamiento principal de diversos tumores hepáticos. Los abordajes laparoscópico y robótico han ampliado las posibilidades de cirugía mínimamente invasiva, especialmente en procedimientos técnicamente complejos. Objetivo: Sintetizar la evidencia científica sobre los resultados y beneficios clínicos de la cirugía laparoscópica versus robótica en la resección de tumores hepáticos. Metodología: Se realizó una revisión bibliográfica narrativa mediante búsquedas en PubMe …

03.09.2026journal-article

Journal of Clinical Medicine

The Impact of Glucagon-like Peptide-1 (GLP-1) Receptor Agonists on Body Composition in Individuals with Overweight and Obesity: A Systematic Review and Meta-Analysis

Miłosz Woźniak, Zofia Tarcz, Gabriela Pyczek, Julia Bogacka, Andrzej Diniejko, Alina Kuryłowicz, Artur Mamcarz, Daniel Śliż

Background/Objectives: Excess adipose tissue is associated with adverse changes in muscle metabolism and body composition. GLP-1 receptor agonists (GLP-1 RA) have transformed the treatment of obesity; however, concerns remain regarding the potential impact of treatment-associated weight loss on lean mass. This study aimed to evaluate the effects of GLP-1 RA on body composition in adults with obesity without type II diabetes mellitus (T2DM), with a particular focus on changes in lean mass. Methods: A database search …

03.09.2026journal-article

Buildings

Restorative Experiences Associated with Built Heritage Settings: The Role of Cognitive and Emotional Pathways in Public Mental Well-Being

Kai Zhu, Hui Tang

Built heritage environments are increasingly recognized as important components of the built environment that shape human experiences beyond their cultural and historical values. However, how heritage-related experiences are associated with restorative perceptions through cultural interpretations and human–place relationships remains insufficiently understood. This study examines the mechanisms underlying perceived restorativeness in built heritage environments by integrating heritage identity and place attachment. …

03.09.2026journal-article

Healthcare

Association of Aspirin Use with In-Hospital Mortality in Patients with Radiation-Associated Acute Pneumonitis: Insights from the National Inpatient Sample Database

Akash Sharma, Shalini, Sowntappan Balasubramanian, Hamza Yousaf, Ankit Agrawal, Vrinda Vyas

Introduction: This study investigates the relationship between long-term aspirin use and mortality in patients experiencing acute radiation-induced pulmonary complications. Methods: We conducted a secondary analysis from the National Inpatient Sample from 2016 to 2020. Our cohort comprised patients diagnosed with acute pneumonitis secondary to chest radiation. We adhered strictly to the STROBE checklist, extracting various patient characteristics for analysis. Categorical variables were compared using Pearson’s chi …

03.09.2026journal-article

International Journal of Computer Science and Mathematical Theory

Mathematical Modelling of Epidemiological Infectious Disease Transmission Dynamics: Public Health Intervention Strategies

Christiana Nkuturum

This study explores the epidemiological infectious disease transmission dynamics with public health intervention strategies using nonlinear ordinary differential equations with four compartments in a mathematical modeling approach. The study identified two major public intervention strategies as preventive and treatment measures. The findings of this study are that the region D of the subset is a positively-invariant set mathematically and epidemiologically from the model equation (1) as a result of the two interve …

03.09.2026journal-article

CIVIL SOCIETY IN RUSSIA AND ABROAD

Public Participation in Law Enforcement: Forms and Areas of Implementation

Ivan V. Teplyashin

The development of democratic institutions in the modern national legal system ensures the broad participation of public structures in legal activities, the determination of their status and scope of legal opportunities, their real place in constitutional and legal relations. Special attention should be paid to the possibility of participation of citizens and their associations in law enforcement activities as one of the conditions for strengthening citizens' trust in public authorities and the formation of high-qu …

03.09.2026journal-article

Mental Health and Social Inclusion

Patriarchal career constraints and mental well-being among rural young women: a scoping review of gendered barriers and psychological distress

Shreya Rana, Sunita Dhenwal

Purpose This paper aims to examine the relationship between patriarchal career constraints and mental well-being among rural young women. It explores how gendered barriers related to family authority, restricted mobility, educational discontinuity, marriage expectations and limited employment exposure contribute to psychological distress and social exclusion. Design/methodology/approach This paper adopts a scoping review approach to map and synthesise literature on patriarchy, rural young women, career barriers, ps …

03.09.2026journal-article

Scientific Reports

Genomic and epidemiological comparative analysis of clinical Campylobacter isolates from public and private healthcare centers in Santiago, Chile

Dona Benadof, Mirta I. Acuña-Ávila, Mireya Ahumada, Lorena Porte, Thomas Weitzel, Alfonso Fernández, Gabriel Cavada, Christopher Grim, Narjol González-Escalona, Carlos J Blondel, Assaf Katz, Verónica Bravo

Abstract Campylobacteriosis remains underestimated in Latin America due to limited surveillance and diagnostic capacity. In this context, a comparison was made of clinical Campylobacter strains from two distinct healthcare settings in Santiago, Chile: a public pediatric hospital and a private tertiary clinic. Through genomic analysis, host-source attribution was observed to vary across socioeconomic profiles: poultry-associated lineages (such as ST-353 and ST-443 complexes) were, as expected, frequently identified …

03.09.2026journal-article

BMC Cancer

Towards a universal ovarian cancer biomarker model: clinical validation of Trx1 and CA125 dual strategy

Mi A Park, Songhak Kim, Xiaoguang Yang, Jong Am Song, Geon Woo Lee, Heon Jong Yoo, Soyoung Kim, Kyoung Hoon Suh, Young Bok Ko

Abstract Background Ovarian cancer is the fifth leading cause of cancer-related mortality in women, with early detection being critical for improving patient outcomes. Current diagnostic biomarkers, including Cancer antigen 125 (CA125), human epididymis protein 4 (HE4), and their combined Risk of Ovarian Malignancy Algorithm (ROMA), exhibit limited sensitivity and specificity, particularly in early-stage disease and premenopausal women. Thioredoxin-1 (Trx1) has emerged as a potential complementary biomarker. This e …

03.09.2026journal-article

Journal of Community Health Provision

Association of Lipid Profile, Glycated Hemoglobin (HbA1c), and Hypertension History with Coronary Artery Disease among Adult Patients: A Cross-Sectional Study

Witi Karwiti, Nasrazuhdy Nasrazuhdy, Wuni Sri Lestari, Nurhayati Nurhayati, Yusneli Yusneli, Asrori Asrori

Coronary artery disease (CAD) remains a major cause of cardiovascular morbidity and mortality worldwide. This study aimed to examine the association of lipid profile, glycated hemoglobin (HbA1c), and hypertension history with CAD among adult patients. A cross-sectional analytical study was conducted among 40 adult patients undergoing cardiovascular evaluation at Abdul Manap Regional General Hospital, Jambi, Indonesia, including 20 patients with CAD and 20 participants without CAD. Demographic characteristics, lipid …

03.09.2026journal-article

Frontiers in Immunology

Complete and durable remission in a patient with brain metastasis from gastric cancer treated with SRS followed by RC48 plus camrelizumab after progression on chemo-immunotherapy: a case report and literature review

Xiao Liu, Baozhen Ma, Mengjiao Yang, Lingdi Zhao

Background Brain metastasis from gastric cancer carries a dismal prognosis, with median overall survival of only 3–6 months. Patients who progress on immune checkpoint inhibitor (ICI)-containing regimens have limited salvage options. HER2-low expression (IHC 1+ or IHC 2+/FISH-negative), historically excluded from anti-HER2 therapy, has now emerged as a novel therapeutic target for antibody-drug conjugates (ADCs) such as RC48 (disitamab vedotin). Case summary A 52-year-old male with HER2-low (IHC 2+/FISH-negative), …

03.09.2026journal-article

F1000Research

Artificial Intelligence-Assisted Community Eye Screening in Primary Healthcare: A Prospective Multicentre Diagnostic Accuracy and Implementation Study

Debapriya Mukhopadhyay, Ankit Varshney, Rajib Mandal, Shoubhik Chakraborty, SK Jahir, Anik Dingal, Apurbayan Biswas, Vishakh Nair, Hlabje Carel Masemola, Swati Mukhopadhyay, Shreyasi Mukherjee, Harinath Mukherjee

Background Artificial intelligence (AI)-assisted retinal screening may extend access to eye care in primary healthcare, but prospective evidence on diagnostic performance and implementation under routine community conditions remains limited. Methods We conducted a prospective multicentre diagnostic accuracy and implementation study across 12 urban and rural community eye-screening centres in India from 1 January to 30 June 2025. Adults aged ≥18 years underwent AI-assisted retinal-image analysis followed by masked c …

03.09.2026journal-article

Frontiers in Pediatrics

Transcatheter embolization as a rescue therapy for refractory pelvic kaposiform hemangioendothelioma with Kasabachi–Merritt phenomenon: a case report

Yi Xiong, Qi Di, Sanlin Li, Jiajie Cao, Chenghao Chen, Gang Shen

Kasabach–Merritt phenomenon (KMP) is a life-threatening consumptive coagulopathy in children with kaposiform hemangioendothelioma (KHE) or tufted angioma. Until now, there has been no well-accepted treatment regimen in the literature. A pelvic KHE is very rare and its deep anatomical location and invasive growth pattern toward adjacent vital organs pose significant management challenges. Here, we report a 10-month-old girl presenting with KMP secondary to a pelvic KHE. Initial systemic therapy with sirolimus and co …

03.09.2026journal-article

International Journal of Legal Medicine

A technical note on the preparation and staining of unfixed, undecalcified and unembedded fresh and taphonomically altered human bone with five common stains and dyes

Simona A. Dinu, Iris Sluis, Wilma Duijst, Tristan Krap

Abstract Anthropological and forensic investigations often rely on skeletonized human remains as the only piece of evidence for lifestyle, age and post-mortem interval predictions. Recent studies have demonstrated that histological staining has the potential to extend or improve the knowledge that can be extracted from the microstructure of bone. However, histological staining has only been scarcely applied and investigated on (taphonomically altered) human bones, leading to a lack of available methodology. In this …

03.09.2026journal-article

Frontiers in Immunology

Traditional Chinese medicine remodels the immune microenvironment of colorectal cancer: mechanisms and therapeutic perspectives

Zeanbang Shi, Jie Mei, Qinchang Zhang, Liu Li, Haibo Cheng

Colorectal cancer (CRC) is a common malignancy of the digestive tract, and its initiation and progression are closely associated with dysregulation of the tumor immune microenvironment. The CRC immune microenvironment consists of effector immune cells, immunosuppressive cells, inflammatory mediators, immune checkpoint pathways, stromal cells, the extracellular matrix, the gut microbiota, and microbial metabolites. Its pathological features include impaired immune recognition and effector immunity, enhanced immunosu …

03.09.2026journal-article

Frontiers in Dental Medicine

A novel image-based algorithm to support future remote assessment of chewing function

Dawn Branley-Bell, Richard Brown, Elias Obreque-Sepúlveda, Claire McGrogan, Helen Cartner, Elhassan Mohamed, Chee Siang Ang, Robert Pellegrino

Background Chewing difficulty is associated with poorer physical and mental health. Objective measurement of chewing function is currently limited to methods that require specialist lab equipment (for example lab-based manipulation or comminution tests). A remote method for estimating chewing-related metrics would support the development of accessible and scalable means of detecting and monitoring chewing-related health issues. Method This paper details initial work on developing a novel smartphone-based, image-ana …

03.09.2026journal-article

Frontiers in Neuroscience

Multimodal neuroimaging fusion in presurgical evaluation of drug-resistant epilepsy: current evidence, clinical integration, and future directions

Yuying Zhao, Mingli Wang, Bo Shen, Wei Luo

Approximately 30% of patients with epilepsy are drug-resistant, and for many of them surgical resection of the epileptogenic zone (EZ) offers the best chance of seizure freedom. Because the EZ cannot be measured directly by any single test, it must be inferred from the convergence of complementary imaging markers, and multimodal neuroimaging fusion has therefore become central to modern presurgical evaluation. This critical narrative review examines what each modality—structural MRI, [18F]FDG-PET, ictal SPECT/SISCO …