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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Frontiers in Medicine

Necroptosis–senescence crosstalk in tubulointerstitial fibrosis: the mtDNA–cGAS–STING–PFKFB3 axis as a metabolic bridge

Donghui Wang, Hongxiang Zheng, Xinyue Zhang, Chenghua Zhang, Dandan Zhao, Shuqi Min, Shenju Wang

Background Chronic kidney disease progresses irreversibly toward tubulointerstitial fibrosis. Although renin-angiotensin system inhibitors and sodium-glucose cotransporter 2 inhibitors slow progression, they cannot block or reverse fibrosis. Recent work shows that necroptosis and cellular senescence in tubular epithelial cells are not independent events; they form a dynamically evolving continuum through the mitochondrial DNA-cyclic GMP-AMP synthase-stimulator of interferon genes-interferon regulatory factor 3-6-ph …

03.09.2026journal-article

Frontiers in Cellular and Infection Microbiology

Absolute quantification by mouthwash testing screens severe periodontitis and tracks species-specific microbial response to periodontal therapy

Je-Hyun Eom, Mu-Yeol Cho, Ji-Won Kim, Yunwoo Kim, Jeehyun No, Jiyoung Hwang, Seokwon Kim, Dahye Lee, Hanseung Baek, Bae-Kyung Kim, Young-Youn Kim, Soo-Bok Her, Dong-Yub Ko, Inseong Hwang, Hye-Sung Kim

Background Non-invasive molecular tools that can both screen for severe periodontitis and quantify treatment-associated pathogen changes remain an unmet need. We evaluated a non-invasive multiplex quantitative polymerase chain reaction (qPCR) mouthwash panel providing absolute colony-forming-unit (CFU) quantification of five periodontal pathogens ( Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, Prevotella intermedia, Fusobacterium nucleatum ), and asked whether a single test can both screen fo …

03.09.2026journal-article

Frontiers in Psychiatry

Anxiety- and depression-related somatic symptoms and atlantoaxial disorders: potential mechanistic links and clinical implications

Shuxian Yang, Qianru Li, Wanying Shi, Xiaoyun Liu

Background Anxiety and depressive disorders often include pain, dizziness, headache, fatigue, nausea, and sleep disturbance. These symptoms may also occur in atlantoaxial disorders, but overlap does not establish a shared cause. Objective To examine whether clinical or mechanistic evidence supports an association between objectively defined atlantoaxial disorders and somatic symptom burden in people with anxiety or depression, while distinguishing direct evidence from inferences based on general neck-pain research. …

03.09.2026journal-article

Frontiers in Public Health

Mental disorders in the Black population: a scoping review

Rondinelli Salvador Silva, Yasmim Souza Rodrigues, Eduardo Sodré de Souza, Bruno Pereira da Silva, Luanda Ferreira Dias de Souza, Igor Hagedorn Reis, Ana Paula de Morais e Oliveira, Deivison Faustino Mendes, Patricia Lima Ferreira Santa Rosa

Introduction Mental disorders, psychiatric diagnosis, DSM/ICD classification, and mental health care represent major sources of global morbidity shaped by biological processes, social stressors, structural racism, inequities, and access barriers. In the Black population, racism, discrimination, social exclusion, and institutional bias may affect recognition, diagnosis, treatment, prognosis, and psychiatric outcomes. This scoping review aimed to map and summarize the available evidence on mental disorders in the Bla …

03.09.2026journal-article

Revista Psicologia, Diversidade e Saúde

Vínculos psicossociais e saúde mental de adolescentes: contribuições do psicodrama em interface com o existencialismo no contexto escolar

Gilmar Antoniassi Junior, Díone Gomes Silva

INTRODUCTION: Adolescence is a period of intense biopsychosocial transformations, in which emotional and social challenges may impact mental health, and school represents a strategic space for the promotion of well-being. OBJECTIVE: To analyze the mental health condition of adolescents, highlighting the influence of psychosocial bonds on their reasons for living, and to discuss the contributions of psychodrama in interface with existentialism in the school context. METHODS: This is a descriptive and exploratory stu …

03.09.2026journal-article

Criminal Behaviour and Mental Health

Assault‐on‐Law‐Enforcement: The Complications of Charges for Individuals on Mental Health Court Dockets

Steven Keener, Audrey Morrison

ABSTRACT Background Mental health courts divert individuals with serious mental illness away from imprisonment into community‐based treatment and supervision. Early research indicates that such treatment contracts can reduce recidivism and provide various other benefits. Aspects of eligibility for this diversion option are still under‐researched. Aims To explore the nature of alleged offences against people accepted into mental health courts (on mental health court dockets), and their demographic and mental health …

03.09.2026journal-article

Global Spine Journal

Testosterone Replacement Therapy is Associated With Increased Risk of Pseudarthrosis After Single-Level Anterior Cervical Discectomy and Fusion: A Propensity Matched Analysis

William Han, Kyle Stump, Karim Gubara, Prabhat Gottipati, Stephan Aynaszyan, Theresa Pazionis

Objective To evaluate whether preoperative testosterone replacement therapy (TRT) use is associated with increased risks of pseudarthrosis and reoperation following single-level anterior cervical discectomy and fusion (ACDF). Methods The TriNetX Research Network was queried to identify adult males aged 18 to 89 years who underwent single-level ACDF. Patients were separated into a TRT exposure group within 1 year before initial ACDF procedure as well as comparator cohort without TRT exposure that was matched 1:1 usi …

03.09.2026journal-article

INTERNATIONAL JOURNAL OF HEALTH AND PHARMACEUTICAL RESEARCH

Factors Influencing the Uptake of Health Care Services Among Undergraduate Students of Kwara State University, Malete, Kwara State

Okunade O. Oluwole

Background: Healthcare services are the activity undertaken by individuals who perceive to have a health problem or to be ill for the purpose of finding an appropriate remedy. Traditional herbal medicines have been used to treat malaria for thousands of years and are the source of the two main groups (artemisinin and quinine derivatives) of modern antimalarial drugs. With the problems of increasing levels of drug resistance and difficulties in poor areas of being able to afford and access effective antimalarial dru …

03.09.2026journal-article

INTERNATIONAL JOURNAL OF HEALTH AND PHARMACEUTICAL RESEARCH

Influence of Ethanol, Methanol and N-Hexane Extracts of Kigelia Africana Leaves and Fruits on Oxidative and Biochemical Properties in Induced Diabetic Rats

Erienu Obruche Kennedy

Diabetes mellitus is a common metabolic disorder characterized by sustained hyperglycemia, oxidative stress, and disrupted biochemical parameters. This study investigated the effects of ethanol, methanol, and n-hexane extracts from the leaves and fruits of Kigelia africana on oxidative and biochemical markers in alloxan-induced diabetic rats. The plant materials were extracted using maceration and solvent evaporation methods. Diabetes was induced by a single intraperitoneal dose of alloxan monohydrate. Experimental …

03.09.2026journal-article

Herz

Predicting LDL-cholesterol reduction variability on statin–ezetimibe therapy: insights from “Jena auf Ziel”

Umidakhon Makhmudova, Dieter Lütjohann, Franz Haertel, Anja Kerksiek, Robert Römer, Pellumb Haxhikadrija, Aurel Maloku, Beasat Samadifar, Sylvia Otto, P. Christian Schulze, Oliver Weingärtner

Abstract Background and aims Low-density lipoprotein cholesterol (LDL-C) is a causal risk factor for atherosclerotic cardiovascular disease (ASCVD). ESC/EAS guidelines recommend reducing LDL-C 50% from baseline in patients with myocardial infarction. “Jena auf Ziel” (JaZ) is a prospective cohort study in which early combination therapy with atorvastatin 80 mg and ezetimibe 10 mg was initiated on admission in patients with ST-elevation myocardial infarction (STEMI) to reduce LDL‑C levels early and effectively. Metho …

03.09.2026journal-article

Journal of Pharmaceutical Research and Integrated Medical Sciences

Multimodal AI and Machine Learning for Predictive Risk Stratification, Early Detection, And Clinical Management of Pica: Integrating Etiological and Pathophysiological Biomarkers

Yash Srivastav, Stuti Verma, Kamini Prajapati, Sandeep Prakash, Rajeev Kumar, Anubha Dhuriya, Anup Kumar Sirbaiya, Shivani Singh

Pica is a clinically significant and often overlooked feeding and eating disorder in which individuals have a persistent urge to eat or chew non-nutritious or non-food items and is linked to nutritional, hematological, behavioral, and environmental issues. Human studies have regularly found links between pica and iron deficiency and anemia, as well as between changes in hematological parameters, decreased ferritin, and decreased zinc concentrations; toxic-element exposure may also be a part of certain behaviors (li …

03.09.2026journal-article

Saudi Journal of Medicine and Public Health

Abdominal Tuberculosis: An Interdisciplinary Approach to Diagnosis, Treatment, and Patient Care-An Updated Review

Majd Abdulrhman Almutiri, Eman Mohammad S. Al Dawood, Ashwag Saleem Almuzaini, Thekra Bandar Khalid Albahuoth, Hussam Hussain Abdullah Ashawi, Omar Muteb S. Alhammadi, Musaad Eid Saeed Aldosari, Abdullah Yahya H. Oagde, Awatef Rabah Almamoni

Background: Abdominal tuberculosis is an important extrapulmonary manifestation of Mycobacterium tuberculosis infection and remains a diagnostic challenge because of its variable, nonspecific, and often indolent presentation. Its clinical and pathological similarities with other gastrointestinal diseases may result in delayed or inappropriate diagnosis. Aim: To provide a comprehensive overview of the etiology, epidemiology, pathophysiology, histopathology, clinical presentation, diagnostic evaluation, differential …

03.09.2026journal-article

LATAM Revista Latinoamericana de Ciencias Sociales y Humanidades

Alfabetización en Salud Renal en adultos jóvenes: una estrategia de enfermería para prevenir la enfermedad renal crónica en atención primaria. Búsqueda narrativa

Maria Fernanda Cruz Hernandez, Yaneth Martinez Hernandez, José Arias Rico, Esther Ramírez Moreno, Aldo Pelcastre Neri

La insuficiencia renal crónica (IRC) se define como la pérdida progresiva, permanente e irreversible de la tasa de filtración glomerular a lo largo de un tiempo variable, a veces incluso de años, expresada por una reducción del aclaramiento de creatinina estimado < 60 ml/min/1,73 m2 (1). La enfermedad renal crónica (ERC) constituye un importante problema de salud pública debido a su creciente incidencia, elevada carga económica y repercusiones sobre la calidad de vida. Aunque tradicionalmente se asocia con adultos …

03.09.2026journal-article

Technology and Health Care

Accuracy improvement for heart rate monitoring from bed-based ballistocardiography signals with motion artifacts

Zeya Wang, Zhumu Fu, Hua Wang, Xiutao Cui, Yeping Zheng, Qin Yu, Xin Chen, Qiqi Shao, Bin Feng

Abstract Background Ballistocardiography (BCG)-based heart rate (HR) monitoring faces accuracy degradation due to motion artifacts, limiting its practical deployment. Objective This study aims to enhance HR estimation reliability under motion-contaminated conditions while ensuring real-time performance. Methods A hybrid system integrating adaptive filtering and enhanced continuous wavelet transform (CWT) is developed. The framework localizes motion segments (95.1% accuracy) and employs spectral reconstruction via m …

03.09.2026journal-article

Livers

Early Versus Late Biliary Leakage After Hepatic Resection: Incidence, Risk Profiles, and Clinical Impact of Diagnostic Timing

Giacomo Paolini, Luca Tirloni, Ilenia Bartolini, Matteo Risaliti, Nicola Nocchi, Alessio Morandi, Maria Novella Ringressi, Antonio Taddei, Gian Luca Grazi

Background/Objectives: Post-hepatectomy biliary leakage (BL) remains a major source of postoperative morbidity. While traditional risk models treat BL as a single clinical entity, its chronological presentation follows distinct patterns that raise the hypothesis of distinct underlying pathophysiological mechanisms. This study aimed to stratify post-hepatectomy biliary fistulas into early and late onset to identify unique independent risk factors and clarify their separate risk profiles. Methods: This retrospective …

03.09.2026journal-article

Journal of Biology and Nature

Effect of Spirulina (Spirulina platensis) Administered in Drinking Water on Growth Performance and Health of the Rabbit (Oryctolagus cuniculus) in the Post-weaning Period

Sangaré Sidiki, Ouattara Adidjatou, Silué Fatogoma Etienne, Kimsé Moussa, Konan André Brou, Alassane Méité

Background: Spirulina (Spirulina platensis) is a nutrient-rich microalga that has been investigated as a feed supplement for improving animal growth and health. However, evidence regarding the effects of low doses of spirulina administered specifically through drinking water to rabbits during the post-weaning period remains limited, particularly for growth performance and health-related outcomes. Aims: To evaluate the effect of three doses of spirulina (Spirulina platensis) administered in drinking water on growth …

03.09.2026journal-article

Sports Health: A Multidisciplinary Approach

Sport-Specific Virtual Reality Tasks Reveal Distinct Patterns of Biomechanical Adaptation Compared With the Drop Vertical Jump

Jennifer A. Hogg, Scott Bonnette, Christopher D. Riehm, Staci Thomas, Manish Anand, Christopher A. DiCesare, Kim D. Barber Foss, Jed A. Diekfuss, Katie Beasley, Andrew Schille, Dustin van der Haar, Dustin R. Grooms, Janet Simon, Sophia Ulman, Richard Danilkowicz, Gregory D. Myer, Michael A. Riley

Background: Neuromuscular training (NMT) improves biomechanical risk factors associated with anterior cruciate ligament (ACL) injury yet has failed to abate increasing ACL injury rates at scale. This study assessed sport-specific sensorimotor adaptations resulting from a NMT protocol with additive real-time sensorimotor augmented biofeedback (augmented NMT [aNMT] or sham aNMT) in a standardized drop vertical jump (DVJ) task and in ecologically valid sport-specific tasks performed in a simulated virtual reality (VR) …

03.09.2026journal-article

BMC Medicine

Diagnostic accuracy of attended versus unattended automated blood pressure measurements compared to ambulatory blood pressure monitoring conducted by community health workers in rural sub-Saharan Africa

Ruth K. Lucinde, Modou Jobe, Alexander D. Perkins, Juliet O. Awori, Boniface Karia, Lamin Jobarteh, Robinson Oyando, Catherine Kalu, Sampa Sanneh, Clement Mwagwabi, Elminah Saru, Aurelia Brazeal, Samson Kinyanjui, Robert N. Peck, David A. Leon, Andrew M. Prentice, Benjamin Tsofa, Anoop S.V. Shah, Pablo Perel, Anthony O. Etyang, on behalf of the IHCoR-Africa Collaborators

Abstract Background Community Health Workers (CHWs) are increasingly being involved in screening for hypertension in rural sub-Saharan Africa. However the diagnostic accuracy of CHW-led attended (CHW present during procedure) and unattended (CHW absent) automated blood pressure (BP) in home settings has not been compared. Methods We conducted a cross-sectional, population-based diagnostic accuracy study in two health and demographic surveillance systems in Kenya and The Gambia. A random age-stratified sample of ind …

03.09.2026journal-article

RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218

EXERCÍCIO FÍSICO, IRISINA E CÂNCER: REVISÃO NARRATIVA DOS MECANISMOS MOLECULARES E DAS EVIDÊNCIAS EXPERIMENTAIS E CLÍNICAS

Elias Campos Martins Bonilha

A irisina é uma mioquina liberada predominantemente pelo músculo esquelético durante a prática de exercícios físicos e participa da comunicação entre o tecido muscular e diferentes órgãos. Nos últimos anos, essa molécula tem despertado interesse na oncologia devido ao seu possível envolvimento nos benefícios do exercício sobre o desenvolvimento e a progressão tumoral. Objetivo: Reunir e discutir, por meio de revisão narrativa, as evidências sobre a atuação da irisina produzida pelo exercício físico no câncer, com ê …

03.09.2026journal-article

Nutrition and Health

Antioxidant status and dehydroepiandrosterone sulfate in aging: Evidence from MIDUS 3 biomarkers cohort

Laith Ashour, Leen Altiti, Rand Khawaldeh, Batool Abuqudaira, Rakan Hani Wadi, Mera Jaber, Basae'r Najadat, Shaima Jaber, Rand Ibrahim Awwad, Tuqa Waleed Smadi, Sara Jamal Mohammad

Background Dehydroepiandrosterone sulfate (DHEAS) has been consistently linked to cardiovascular and skeletal health; however, the relationship between circulating antioxidant concentrations, including vitamins, and DHEAS levels in older adults has been insufficiently examined. Aim To assess associations between serum DHEAS and five antioxidants: β-cryptoxanthin, total lycopene, α-tocopherol, γ-tocopherol, and retinol. Methods Data from the Midlife in the United States (MIDUS3) Biomarker Project (2017–2022) were an …

03.09.2026journal-article

Journal of Public and Nonprofit Affairs

Association between Organizational Performance and Job Satisfaction: How Sectoral Identity Moderates the Relationship

Minjung Kim

Job satisfaction is a key element of human resource management, yet the association between organizational performance and employee job satisfaction remains theoretically underdeveloped, particularly regarding the direction of influence and how institutional context shapes this relationship. Drawing on organizational climate theory and social identity theory, this study examines how organizational performance is associated with job satisfaction and whether sectoral identity moderates this relationship. Using a pane …

03.09.2026journal-article

Journal of Pediatric Infectious Diseases

Age-Dependent Variations in Clinical Presentation, Laboratory Parameters, and Coronary Outcomes in Kawasaki Disease: A 10-Year Retrospective Cohort Study of 480 Pediatric Patients in Eastern China

Zhuying Zhou, Chen Wang, Aole Li, Saeed Saboor, Xiaoli Li, Xiaowei Li, Xianmei Huang, Chunming Jiang

Objective: This study investigated the age-dependent clinical characteristics of Kawasaki disease (KD) in pediatric patients and assessed the influence of age on disease presentation and outcomes. Methods: A retrospective analysis was conducted of 480 children diagnosed with KD who were admitted to Hangzhou First People's Hospital between 2013 and 2022. Subjects were stratified into two cohorts based on age:

03.09.2026journal-article

Journal of Endovascular Therapy

Zone 2 Versus Zone 3: Thoracic Endovascular Aortic Repair’s Tough Choice in Acute Type B Aortic Dissection: Systematic Review and Meta-Analysis

Noor Abu Hantash, Hazem El Beyrouti, Yousef Alghzawi, Ahmad Yaish, Leen Aburumman, Abdullah Alzubaidi, Nancy Halloum

Background: Optimal proximal landing zone selection in thoracic endovascular aortic repair (TEVAR) for acute and subacute Stanford type B aortic dissection remains controversial. This meta-analysis compared zone 2 versus zone 3 deployment with respect to perioperative and mid-term outcomes. Methods: This study followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines. PubMed and Scopus were systematically searched up to August 1, 2025. Eligible studies included adult patients with …