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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
22.08.2026journal-article

Diseases of the Esophagus

P1.183. Salvage Surgery and Conversion Surgery for Esophageal Cancer in Patients Aged 80 Years or Older

Hiroshi Sato, Yutaka Miyawaki, Yusuke Suzuki, Yutaka Kishimoto, Shinichi Sakuramoto

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer Background With the rapid aging of the population, esophageal cancer in individuals aged 80 and older continues to increase. Conversely, with recent advances in multidisciplinary treatment, including novel chemotherapies and immune checkpoint inhibitors, “salvage surgery” and “conversion surgery” are increasingly being performed. These procedures often involve more invasive techniques than standard approaches, and their applicability in the e …

22.08.2026journal-article

Forests

Serving More People or Reaching Farther? Landscape Feature Synergies and Trade-Offs in Urban Park Recreational Services

Jingnan Zhu, Xiaoma Li, Li Hu, Peng’ao Liu, Luying Wang, Dexin Gan, Di Shu

Understanding how urban park landscape features are associated with service population and service radius can inform park planning and management. In Changsha, China, this study measured both indicators for 29 parks on one weekday and one weekend day in spring 2025 using mobile signaling data, quantified landscape features from multisource data, and examined their associations. Service population and service radius were not highly correlated. The adjusted R2 values for the two indicators were 71.8% and 84.5%, respe …

22.08.2026journal-article

Revista Eco-Pós

Jovens e Inteligência Artificial

Daniela Silva

Este artigo analisa recomendações e políticas que estão sendo criadas para garantir que o tema da Inteligência Artificial seja incorporado na Educação Básica e no Ensino Superior, de modo que a população, em especial, os jovens estejam capacitados para lidar, criticamente, com as tecnologias emergentes. Aborda-se a presença, cada vez mais comum, da Inteligência Artificial Generativa no cotidiano dos jovens (Google; Educa Insights, 2023; IBM; Morning Consult, 2020; Abmes; Educa Insights, 2024), além de seguir desper …

22.08.2026journal-article

International Journal For Multidisciplinary Research

Formulation And Evaluation Of Anti-Aging Facial Serum Containing Resveratrol-Rich Red Grape Skin Extract

Aishwarya Pandit, Ashwini Pansare -, Arti Ingole -, Dr. Hitanshi Darji -, Sakshi Kohakade -, Pravinkumar Sable -

The growing demand for natural and plant-based cosmetic products has increased interest in the development of herbal formulations with anti-aging properties. Resveratrol, a polyphenolic compound abundantly present in red grape (Vitis vinifera) skin, possesses potent antioxidant, anti-inflammatory, and photoprotective activities that may help prevent premature skin aging. The present study aimed to formulate and evaluate an anti-aging facial serum containing resveratrol-rich red grape skin extract. Red grape skins w …

22.08.2026journal-article

Journal of Travel Research

When Visuals Meet People with Disabilities: How Destination Image Featuring Disability Drives Travel Intention?

Mengfan Li, Lingxue Zhan, Litang Wen, Ji Chen, Mingming Cheng

This research investigates how featuring people with disabilities in tourism destination images on social media shapes viewers’ travel intention. Guided by warm glow theory, a mixed-methods approach was employed, comprising a field study, semi-structured interviews, and five online experiments. The findings demonstrate that including people with disabilities in tourism destination images has a significant positive effect on travel intention. Moreover, the results show that cognitive mechanisms involving self-projec …

22.08.2026journal-article

Journal of Health Psychology

Post-traumatic growth in people with cancer: A meta-synthesis of qualitative studies

Lingling Pan, Jiayue Wu, Qianyun Jiang, Linyan Wang, Yumei Li

This qualitative meta-synthesis systematically reviewed studies on post-traumatic growth (PTG) in people with cancer. A comprehensive search of nine databases was conducted up to February 2025. Following PRISMA guidelines, the methodological quality of included studies was assessed using the JBI checklist, and data were analyzed via thematic synthesis. Fifteen studies, all rated as Level B (moderate quality), were included, generating three core themes: the psychological journey of PTG, its facilitators and barrier …

22.08.2026journal-article

International Journal of Applied Chemistry

Aging of Palm Wine Source: Its Implication on the Physicochemical Properties and Vitamin Content of Palm Wine

Nwachoko Ndidi, Akuru Udiomine Brantley, Chukwudi Omeni Egbunefu, Clement-Aken Victor Obarijima, Goodluck Samuel

Palm wine, a traditional alcoholic beverage widely consumed in sub-Saharan Africa, is derived from the sap of various palm trees. This study investigated the effects of aging of the palm wine source on the physicochemical properties and vitamin content of palm wine for 30 days. Standard laboratory procedures were employed to analyze these parameters. The results revealed significant (P

22.08.2026journal-article

Diabetology & Metabolic Syndrome

The association between a novel visceral lipoprotein risk index and new-onset diabetes in middle-aged and older Chinese adults

Jin Dong, Fan Yang, Lei Luo, Jianhua Liu, Jian Chen, Xiangyang Shao

Abstract Background The global health burden of diabetes continues to grow. While the Chinese Visceral Adiposity Index (CVAI) and low-density lipoprotein cholesterol (LDL-C) are well-established risk factors for diabetes, the potential compounding effect of these factors is not well characterized. This study aimed to explore the relationship between a novel integrative index, the Visceral Lipoprotein Risk (VLR) index, and incident diabetes. Methods This prospective cohort study included 7,559 participants aged ≥ 45 …

22.08.2026journal-article

BMC Psychiatry

Cognitive status and depressive symptoms among older adults: a SEM analysis study

Farnaz Fathollahzadeh, Azadeh Borna, Parvin Dibajnia, Behrooz Mahmoodi-Bakhtiari, Elizabeth D. Leigh, Mahdi Azizi, Alireza Akbarzade Baghban, Seyede Zohre Mousavi

Abstract Background The increase of age is related with high concerns of cognitive decline and depression which frequently influence each other in both directions. The objective of the current study is the assessment of the cognitive status and the symptoms indicating depression the older adults, in order to evaluate a structural model that subjective cognitive complaints mediate the relationship between objective cognitive performance and depression. Methods The current study, cross-sectional in nature, was carrie …

22.08.2026journal-article

International Journal of Molecular Sciences

Geroprotective Effects of Drugs Modulating Metabolic Pathways: Perspectives of Pharmacology in Anti-Aging Therapy

Marta Grycan, Rafał Zyśk, Gabriela Grycan, Grzegorz Jakiel, Alicja Dudek, Grażyna Gromadzka

Aging is the strongest risk factor for chronic diseases such as cardiovascular diseases, cancer, diabetes, and neurodegenerative disorders. Advances in geroscience indicate that pharmacological modulation of conserved molecular pathways may extend healthspan and delay multimorbidity. A structured narrative review of the PubMed, Scopus, and Web of Science literature published between January 2010 and May 2026 was conducted, with seminal earlier studies retained where relevant. The review focused on molecular pathway …

22.08.2026journal-article

Innovation in Aging

Comparing sensor-based activity features of frailty across Fried Frailty Phenotype and deficit-accumulation frailty index

Andrew Song, Kailin Xu, Kuan-Yuan Wang, Lingsong Kong, Stephanie Denise M Sison, Sandra M Shi, Amanda Paluch, Dae Hyun Kim

Abstract Background and Objectives Wearable sensors offer a low-burden approach to assessing frailty in free-living settings, but how sensor-derived features relate to different frailty definitions is unclear. This study compared thigh-worn sensor-derived activity features associated with pre-frail/frail status under the Fried Frailty Phenotype (FFP) and the Comprehensive Geriatric Assessment–Based Frailty Index (CGA-FI). Research Design and Methods We enrolled 44 older adults (mean age 82.3 years, 84% women) from …

22.08.2026journal-article

Nutrients

Effects of a Commercial Fruit, Vegetable and Berry Juice Powder Concentrate on Metabolic Safety and Cardiovascular Health in Older Adults: 6-Month Results of a Randomized Controlled Trial

Tobias Ziegler, Azra Darko, Gerhard Ledinski, Gerd Kager, Gerd Hörl, Andreas Seemann, Gerhard Cvirn, Manfred Lamprecht

Background/Objectives: Fruit, vegetable and berry (FVB) juice powder concentrates are increasingly used to support cardiovascular health. Since they are usually consumed over long periods, this study assessed the metabolic safety of a commercial FVB supplement and its impact on selected biomarkers of systemic oxidative stress and cardiovascular health. Methods: In this open-label, randomized controlled trial, generally healthy older adults were allocated to a control group (n = 16) or an FVB group (n = 18), ingesti …

22.08.2026journal-article

npj Aging

How age and sex interaction is associated with immune aging with implications for vaccines and age-related autoimmunity

Reza Gheitasi, Mahnaz Rezaei, Parvaneh Nafisi Fard, Daniela Roel, Sabine Baumgart, Diana Dudziak, Norman Rose, Simon M. Petzinna, Thomas Kamradt, Carsten Watzl, Mathias W. Pletz, Valentin S. Schäfer

Abstract Immunosenescence is not a uniform decline but a trajectory shaped jointly by age and sex. Using continuous high-dimensional immunophenotyping, we show that aging T cells accumulate a senescent signature of CD28 loss and CD57 gain, and that males reach an inverted CD4:CD8 ratio earlier and more severely than females. We argue that age-by-sex stratification should guide vaccination and geroprotective strategies in an aging population.

22.08.2026journal-article

Healthcare

Factors Associated with Treatment Burden in Older Adults with Multimorbidity and Implications for Potential Reduction Strategies: A Scoping Review

Leandro Amato, Gianluca Ciccaglione, Noemi Giannetta, Emanuele Di Simone, Nicolò Panattoni, Sara Dionisi, Alessandra Improta, Sofia Taborri, Marco Di Muzio

Background: Treatment Burden (TB) refers to the workload imposed on patients by healthcare-related tasks involved in the management of chronic conditions. Despite increasing evidence on this phenomenon, strategies for its reduction in older adults with multimorbidity remain poorly explored. Aim: To map the factors associated with treatment burden reported for older patients with multimorbidity and to derive implications for potential reduction strategies, regardless of the care setting. Methods: A scoping review wa …

22.08.2026journal-article

JNCI: Journal of the National Cancer Institute

Anal cancer burden among people with HIV across US states, DC, and major metro areas

Ashish A Deshmukh, Haluk Damgacioglu, Kalyani Sonawane, Cameron Haas, Qianlai Luo, Anna Satcher Johnson, Eric A Engels, Meredith S Shiels

Abstract Background Anal cancer screening is recommended for people with HIV in the United States (US). Because HIV prevalence varies geographically, the distribution of anal cancer diagnoses occurring among people with HIV may also differ by geography. Characterizing geographic variation can help identify areas needing enhanced screening infrastructure and outreach. Methods Using data from the HIV/AIDS Cancer Match Study, US cancer registries, and CDC’s National HIV Surveillance System, we estimated the proportion …

22.08.2026journal-article

Journal of Intellectual Disability Research

Well‐Being in First Person: A Relational Construction of Psychological Well‐Being Among Young People With Intellectual Disabilities

Javier Piñeiro‐Cossio, Paz Cancino, Ignacia Celis, Saray Santana

ABSTRACT Background Psychological well‐being (PWB) has become a central construct in contemporary psychology; however, young people with intellectual disabilities (ID) remain largely underrepresented in well‐being research. Much of the available evidence relies on proxy reports from caregivers or professionals, limiting understanding of how young people with ID themselves conceptualize and experience well‐being. This qualitative study explores the meaning of psychological well‐being from a first‐person perspective …

22.08.2026journal-article

BMC Geriatrics

Assessing concerns about falling: a comparison of telephone-based and face-to-face FES-I interviews in older adults

Anja Müller, Robert Kob, Ellen Freiberger, Nicolas Rohleder, Sabine Britting

Abstract Background Concerns about falling (CaF) are commonly assessed using the Falls Efficacy Scale-International (FES-I), but telephone versus face-to-face interviews may influence responses. The objective of this secondary paired method-comparison analysis was to assess agreement between telephone and face-to-face FES-I total scores in older adults and to explore whether the two administration modes differed at the total-score and item levels. Methods Data were drawn from the FEARFALL study, a longitudinal rand …

22.08.2026journal-article

BMC Public Health

The interplay of influencing factors in physical activity promotion for older men: insights through the capability approach

Tizian Schuck, Julika Loss, Susanne Tittlbach

Abstract Background The capability approach has gained increasing attention in the context of health and physical activity promotion due to its focus on individuals’ freedoms to achieve desired outcomes. Its empirical application remains limited, particularly among older men, a group often underrepresented in physical activity promotion. This study applies the capability approach as a theoretical framework to investigate the relationship between individual and socio-structural conversion factors, perceived capabili …

22.08.2026journal-article

Journal of Neurology

Language impairments in behavioural variant frontotemporal dementia: a comparative study with semantic dementia

Sharon Savage, Ohnmar Aung, David Foxe, Olivier Piguet

Abstract Introduction Recent evidence suggests that individuals with behavioural variant frontotemporal dementia (bvFTD) may experience language changes in a similar, but less severe manner, than what is observed in semantic dementia (SD). Few studies, however, have specifically compared these patient groups or considered the cognitive underpinnings. To explore this in more depth, this study aimed to profile patterns of language performance within both "probable" and "possible" categories of bvFTD and to compare th …

22.08.2026journal-article

Scientific Journal of Sport and Performance

A broader range of jump-performance characteristics associated with 50-m sprint performance in older children

Yusuke Hioki, Kosuke Suzuki, Ryohei Hayashi

Although jump performance is associated with sprint ability in children, it remains unclear whether different jump tasks show similar relationships with sprint performance across chronological age and sex groups. This cross-sectional study examined associations between 50-m sprint performance and countermovement jump (CMJ), rebound jump (RJ), and standing long jump (SLJ) performance in 196 children aged 9–12 years. Participants were classified into 9–10- and 11–12-year groups and analyzed by sex. Overall and 10-m s …

22.08.2026journal-article

Arandu UTIC

Bienestar sociofamiliar y acción de los grupos de apoyo a personas adultas mayores de la comunidad San Eloy

Luisa Michelle Alcívar Vélez, Eva Margarita Alcivar Medranda

Durante el envejecimiento, factores como la pérdida de roles y la reducción de la autonomía, tienen una afectación directa sobre la calidad de vida de los adultos mayores, un problema que se intensifica en zonas donde los servicios son limitados como el cantón Rocafuerte – Provincia de Manabí - Ecuador. El objetivo general consistió en analizar el bienestar sociofamiliar y acción de los grupos de apoyo a personas adultas mayores de la comunidad San Eloy. Se aplicó una metodología cualitativa bajo un diseño descript …

22.08.2026journal-article

Aging Cell

Network Model to Predict Age‐Related Transcriptional Reprogramming

Tyler J. McNeill, Fabrisia Ambrosio, Hirotaka Iijima

ABSTRACT Understanding how secreted factors from aged tissue, often referred to as the senescence‐associated secretome, reshape cellular phenotypes remains a major challenge due to the complexity of downstream molecular cascades. Here, we present a computational framework for in silico perturbation modeling designed to predict distinct transcriptional responses to age‐specific extracellular environmental cues. We exemplify applications of this framework using articular chondrocytes exposed to secretomes derived fro …

22.08.2026journal-article

Diseases of the Esophagus

P1.166. Preoperative Geriatric Nutritional Risk Index (GNRI) as a Predictor of Intraoperative Hypothermia in Esophageal Cancer Surgery

Weiming Chen, Xiamei Chen, Sufang Ye, Huangxiang Chen, Hui Jiang, Weimin Fang, Weikun Su

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications Background Esophageal cancer is life-threatening, and esophagectomy patients have a high incidence of intraoperative hypothermia (linked to adverse postoperative outcomes), with no stable predictive indicator available. The Geriatric Nutritional Risk Index (GNRI), a validated tool for predicting cancer prognosis/complications, has not been studied for its association with intraoperative hypothermia in esopha …

22.08.2026journal-article

BMC Health Services Research

Domestic violence among healthcare professionals in Sweden - Prevalence, associations with asking older patients about abuse and reactions to participating in training on abuse of older people

Johanna Simmons, Mikael Ludvigsson

Abstract Background Different forms of domestic violence, including abuse of older people (AOP), are prevalent and associated with poor health outcomes. The healthcare system is therefore often considered an important context for identifying victims of violence and providing referrals. However, healthcare professionals may also have their own experiences of domestic violence. The aims of this study were to: (1) investigate the prevalence of domestic violence, specifically intimate partner violence (IPV) and violenc …