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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
02.09.2026journal-article

American Journal of Alzheimer's Disease & Other Dementias®

Are the “Serial 7s” and Spelling Backwards Tasks From the MMSE Comparable in MCI and Dementia?

Edoardo Nicolò Aiello, Giulia De Luca, Arianna Moreschi, Beatrice Curti, Francesco Cazzini, Andrea Cerri, Selene Saba, Valerio Patisso, Alessio Maranzano, Vincenzo Silani, Nicola Ticozzi, Federico Verde, Barbara Poletti

We explored the comparability of the “Serial 7s” (S7) and Spelling Backwards (SB) tasks from MMSE in 313 patients with MCI ( N =54) and dementia ( N =259) due to Alzheimer’s disease (AD), frontotemporal lobar degeneration, Lewy body disease, non-AD degenerative (NADD), chronic cerebrovascular disease (CVD) or mixed (AD+CVD) etiologies. Although the two tasks were significantly associated with each other ( r =.54), a two one-sided test revealed that they were not statistically equivalent. Consistently, a linear mixe …

01.09.2026journal-article

International Journal of Pharmacy Practice

The clinical burden of potentially inappropriate medications on hospitalization risk in an Italian older adult cohort: a large-scale real-world study

Andrea Rossi, Elena Olmastroni, Gerard Ompad, Manuela Casula, Maurizio Sessa

Abstract Introduction Optimizing drug treatments in older adults is essential for improving health outcomes and reducing drug-related issues. Objective This study aimed to develop an updated and comprehensive explicit indicator of potentially inappropriate medications in older adults, and to evaluate its association with all-cause hospitalization. Methods Administrative healthcare data from Local Health Units (LHUs) in Lombardy, Italy (2015–2018) were used to identify individuals aged ≥65 years who were exposed to …

02.09.2026journal-article

Alzheimer's & Dementia

A world view: Considerations of sociocultural diversity in the study of subjective cognitive decline in Alzheimer's disease and related dementias

Mark A. Dubbelman, Tanisha G. Hill‐Jarrett, Silvia Chapman, Gustavo Alves Andrade dos Santos, Martina Azar, Ganesh M. Babulal, Tyler R. Bell, Mark A. Bernard, Carolina Boza‐Calvo, Anthony Q. Briggs, Omonigho Michael Bubu, Heather E. Cuevas, N. Maritza Dowling, Darlingtina K. Esiaka, Bernadette A. Fausto, Fabricio Ferreira de Oliveira, Carol E. Franz, Joyla A. Furlano, Christopher Gonzalez‐Corona, M. Aaron Guest, Veer Bala Gupta, Vivek K. Gupta, Daija Jackson, Jillian L. Joyce, Michael R. Kann, William S. Kremen, Athene Lee, Jairo E. Martinez, Arjun V. Masurkar, Maia A. McLin, Elisa de Paula França Resende, Zahra Rahemi, Brianca C. Renfro, Márlon Juliano Romero Aliberti, Shaina Shagalow, Andrea Slachevsky, Juliana N. De Souza Talarico, Jean François Trani, Carol Van Hulle, Leah Waltrip

Abstract Subjective cognitive decline (SCD) refers to cognitive concerns that may occur with or without objective impairment on standardized testing. Studies suggest that SCD may be an early clinical marker of Alzheimer's disease and related dementias, and that it can predict future objective cognitive decline and progression to dementia. However, the research that supports these conclusions is primarily based on samples with homogeneous socioeconomic and cultural backgrounds. The limited studies in samples with mo …

01.09.2026journal-article

JMIR Research Protocols

A Culturally Grounded Music-Based Intervention for Indigenous Older Adults in Long-Term Care: Protocol for a Mixed Methods Pilot Study

Ariel L Roddy, Katherine Mommaerts, Rebecca Maniglia, Juliette Roddy, Craig Yarbrough, Julie A Baldwin

Abstract Background Indigenous communities continue to experience significant mental and physical health disparities associated with historical trauma, structural inequities, and disruptions to cultural continuity. Indigenous older adults residing in long-term care settings may be particularly vulnerable to social isolation, psychological distress, chronic pain, and reduced opportunities for cultural engagement. Music-based interventions (MBIs) have demonstrated potential for improving psychosocial and physical hea …

01.09.2026journal-article

Al-Rafidain Dental Journal

Prevalence and Classification of Impacted Maxillary Canine in People living in Duhok City by using Cone Beam Computed Tomography (CBCT)

Ban Taha Mustafa, Saleem Khadir Musalah

Aims: The present study aimed to employ CBCT technology to investigate the prevalence, gender distribution, and classification (following Archer's 1975 method) of impacted maxillary canines in Duhok City in order to establish a standard for local clinical practice Materials and Methods: In this retrospective cross-sectional study, 4,368 CBCT scans from various private clinics and dentistry centers in Duhok City between 2021 and 2026 were examined. The study sample comprised 2,111 males and 2,257 females, aged 12 to …

01.09.2026journal-article

Buildings

The Impact of Nursing Home Environmental Expectation Gaps on Residential Adaptation Among Older Adults: Evidence from Inclusive Nursing Homes in Changchun, China

Boyu Du, Hang Zhang, He Liu, Wanying Qin, Xiaolong Zhao, Jinghao Zhao

This study examined how environmental expectation gaps, defined as discrepancies between older adults’ expectations before admission and their actual experiences after admission, are associated with residential adaptation in nursing homes. Survey data from 613 residents of six public and private inclusive nursing homes in Changchun, China, were analyzed using structural equation modeling and bias-corrected bootstrapping. Expectation gaps in safety and mobility convenience, privacy and autonomy, environmental comfor …

04.09.2026journal-article

Aging Cell

Tissue‐Level Transcriptomic Entropy Reveals Organ‐Specific Aging Patterns and Predicts Cancer Progression

Gabriel Arantes dos Santos, José Pedro Castro, Gabriela D. A. Guardia, Filipe F. dos Santos, Alexander Birbrair, Pedro A. F. Galante

ABSTRACT Although aging and cancer share complex molecular mechanisms, distinguishing causative factors from byproducts remains challenging. Here, we investigated the role of tissue transcriptomic entropy—a measure of transcriptional disorder—in aging and cancer processes by analyzing RNA‐sequencing data from over 25,000 samples from human and mouse tissues. We found that entropy changes during aging are highly tissue‐specific, with some tissues showing increased entropy while others exhibit decreased or stable ent …

04.09.2026journal-article

Aging Cell

Akkermansia muciniphila and Its Bioactive Derivatives: Emerging Regulators of Healthy Aging

Ting Zhang, Jinyuan Niu, Xiaoyu Hu, Zhiang Hu, Yuan Gao, Jialiang Liu, Ning Chen, Yaomin Hu

ABSTRACT The global aging trend underscores the urgent need for innovative interventions against aging‐related decline. Accumulating evidence identifies Akkermansia muciniphila ( A. muciniphila ) as a key gut microbiota regulator of aging, with its depletion associated with age‐related diseases (ARDs), whereas its abundance is enriched in healthy centenarians. This review summarized current evidence linking A. muciniphila to aging, examining their causal relationship, the roles of its bioactive derivatives, underly …

01.09.2026journal-article

Quality in Ageing and Older Adults

Intergenerational programme as a strategy to enhance older adults’ life satisfaction in urban communities

Ni Made Riasmini, Riyanto Riyanto, Meirina, Subandi Subandi, Amid Salmid, Gurid Pramintarto Eko Mulyo

Purpose Population ageing is a global phenomenon, including in Indonesia, where the number of older adults continues to increase. Life satisfaction is an important indicator of subjective well-being among older adults and is influenced by social engagement and interpersonal relationships. Intergenerational programmes have been developed to strengthen interactions between older adults and younger generations; however, empirical evidence in urban communities in Indonesia remains limited. This study aims to analyse th …

01.09.2026journal-article

Evolutionary Applications

A Comparative Analysis of Aging Across Causes of Death

Gabriele Sorci, Bruno Faivre

ABSTRACT Although there is huge variation in how mortality changes with age across species, in humans, all‐causes mortality increases at a relatively constant rate across populations and time. However, individuals die due to specific causes that include extrinsic and intrinsic sources. Here, we compared the rate at which mortality increases with age (i.e., the rate of aging) for the causes of death supposedly referring to extrinsic (infectious and parasitic diseases) and intrinsic sources (cardiovascular diseases a …

02.09.2026journal-article

BMJ Open

Which methodologies and methods should be used for psychosocial intervention research in dementia? Protocol for a stakeholder-driven, multi-method Delphi study

Sara Laureen Bartels, Federica D’Andrea, Alice Burnand, Simone R De Bruin, Ilaria Chirico, Emma Elliott, Aisling Flynn, Lesley Garcia, Doris Gebhard, Melanie Handley, Niels Janssen, Patricia Masterson-Algar, Marine Markaryan, Martina Roes, Nathan Stephens, Lieve Van den Block, Esme Moniz-Cook, Maud Graff

Introduction Psychosocial interventions are essential to support people living with dementia and their carers. A consensus on what is most important for research on psychosocial intervention in dementia and how intervention studies should best be conducted is currently lacking. This protocol describes the research plan aimed at achieving consensus on (i) the relevance of core elements (CEs) for the development, feasibility testing/piloting, evaluation and/or implementation phases of psychosocial interventions in de …

01.09.2026journal-article

Journal of Applied Physiology

Oxygen cost of breathing and its association with dyspnea in older patients with heart failure with preserved ejection fraction and obesity

Bryce N. Balmain, Valentin Mons, Andrew R. Tomlinson, James P. MacNamara, Abidan Abulimiti, Michael G. Leahy, Denis J. Wakeham, Kevin Lutz, Linda S. Hynan, Benjamin D. Levine, Satyam Sarma, Tony G. Babb

This study shows that the oxygen cost of breathing is higher in patients with heart failure with preserved ejection fraction and obesity compared with healthy older adults without obesity but is not different from that of healthy older adults with obesity. A higher oxygen cost of breathing is further associated with a greater magnitude of obesity, more pronounced exertional dyspnea, and reduced exercise tolerance.

01.09.2026journal-article

Cancer Nursing

A Scoping Review of the Perceptions and Experiences of People From Underserved Groups of Being on Personalized Stratified Follow-Up Following Treatment for Breast Cancer

Katie Sutton, Sophie McGrevey, Verna Lavender, Lorraine Marke, Jo Armes

Background: Personalized Stratified Follow-Up (PSFU) is an approach to cancer follow-up involving patients re-accessing care when they need to, rather than attending predetermined appointments. The benefits of this approach are a more personalized experience for patients and increased capacity in clinics. Objective: To understand the evidence relating to the experiences of people on PSFU following breast cancer treatment, specifically in terms of the perceptions of people from underserved groups. Methods: A scoping …

01.09.2026journal-article

Foods

Behavior of Shiga Toxin-Producing Escherichia coli in Naturally Contaminated Bovine Raw Milk Cheese During Aging

Giulia Weiss, Ilaria Prandi, Sonia Rodas, Marzia Mancin, Andrea Massaro, Nicola Cologna, Marco Nardelli, Marco Ramelli, Barbara Cardazzo, Simone Belluco, Rosaria Lucchini

Shiga toxin-producing Escherichia coli (STEC) are foodborne pathogens of concern in raw milk dairy products. Ensuring product safety requires regular own-check testing, but evidence on naturally occurring STEC behavior during aging remains limited. This study analyzed three batches of bovine raw milk washed-rind cheese produced with STEC-positive curds to evaluate: (I) STEC distribution within cheese wheels and (II) STEC behavior during aging. STEC detection followed ISO/TS 13136:2012. First, two cheese wheels from …

01.09.2026journal-article

Geriatrics & Gerontology International

Self‐Application of Aging Stereotypes as an Independent Predictor of Loneliness in Community‐Dwelling Older Adults: A Cross‐Sectional Study

Rahime Aslan, Mahsun Toplu

ABSTRACT Aim Loneliness is common in later life and may be shaped by aging stereotypes. Drawing on Stereotype Embodiment Theory, this study examined whether the components of aging‐stereotype internalization predict loneliness independently of sociodemographic factors and whether effects differ by dimension. Methods In this cross‐sectional study, 485 community‐dwelling adults aged 65 or older in Turkey completed the Elderly Internalized Stigma Scale (EISS), indexing awareness, agreement, and self‐application, and t …

03.09.2026journal-article

Aging Cell

In Vivo Base Editing Partially Rescues Bone Dysplasia in a Mouse Model of Hutchinson‐Gilford Progeria Syndrome

Wayne A. Cabral, Caleb M. Grenko, Diana Yeritsyan, Indeevar Beeram, Shubham Laiwala, Lukas R. Johnson, Urraca L. Tavarez, Tingfen Yan, Stephen M. Wincovitch, Luke W. Koblan, Xin D. Gao, Meirui An, Narisu Narisu, Leslie G. Biesecker, David R. Liu, Ara Nazarian, Francis S. Collins, Michael R. Erdos

ABSTRACT Hutchinson‐Gilford progeria syndrome (HGPS) is a premature aging disorder affecting tissues of mesenchymal origin. Most patients harbor a c.1824C>T/p.G608= variant, commonly described as G608G, in exon 11 of LMNA that leads to aberrant splicing and production of the toxic progerin protein. In addition to cardiovascular, dermal, and adipose tissue deterioration, HGPS mouse models also develop progressive bone dysplasia that occurs in patients. Here we characterize the efficacy of in vivo mutation correction …

02.09.2026journal-article

Brain and Behavior

Cognitive Reserve and Psychological Well‐Being in Aging Population of Community‐Dwellers in Spain

Mikhail Ordin, Angel Barrasa, Caridad López‐Granero, Leona Polyanskaya

ABSTRACT Introduction Greater brain resilience—the capacity of the brain to maintain normal functioning and cognition with aging—is associated with a slower cognitive decline. Cognitive reserve (CR) is one component of brain resilience and may be supported by educational, occupational, and leisure experiences. Purpose This exploratory, cross‐sectional study examined associations among psychological well‐being, engagement in leisure activities associated with cognitive reserve, and cognitive performance in older com …

31.08.2026journal-article

The Korean Gerontological Research Society

Types of Family Caregiving and Psychological Well-being in Older Adults: Moderating Effects of Social Support and Age-Group Comparisons

Minji Shim, Giyeon Kim

This study examined the effects of family caregiving types on the mental health (depression, life satisfaction) of Korean older adults and the moderating role of social support, focusing on the differences between the young-old (65-74) and the old-old (75+). Data from the 2023 National Survey of Older Koreans for older adults (N=9,945) were analyzed using hierarchical regression and simple slope analysis. The results show that both single and multiple caregivers reported significantly higher life satisfaction than …

31.08.2026journal-article

International Journal of Advanced Research

BEHAVIORAL INTERVENTIONS FOR ORAL CARE IN COGNITIVELY IMPAIRED OLDER ADULTS

Ekaterina Kokoreva, Satwinder Singh, Saniya Sohail, Kashmala Khalil, Kainat Faraz, Bhumika Sharma

Cognitive impairment, including dementia and Alzheimer's disease, compromises older adults' ability to maintain oral hygiene, leading to increased dental plaque, periodontal disease, and tooth loss. Care-resistant behaviors during oral care present significant barriers to effective hygiene maintenance. This narrative review evaluates behavioral interventions designed to improve oral care practices amon cognitively impaired older adults. A comprehensive search of electronic databases including PubMed, Embase, CINAHL …

31.08.2026journal-article

Frontiers in Public Health

Primary healthcare professionals’ perspectives on mobility limitation assessment and predictive model optimization for community-dwelling older adults: a qualitative research

Linbing Chen, Ye Ouyang, Chunyu Cheng, Xiyi Liu, Yanfei Xiang, Liping Wang

Background Mobility limitation is an important public health challenge faced by ageing populations. However, standardized assessment tools remain lacking in primary care practice in China, and existing predictive models still face substantial implementation gaps in clinical translation. This qualitative study aimed to explore frontline primary healthcare professionals’ perceptions of current assessment practices and to provide recommendations for optimizing and clinically translating related predictive models. Meth …

31.08.2026journal-article

Revista de Estudios e Investigación en Psicología y Educación

Estereotipos infantiles sobre las personas mayores

Silvia MARTÍNEZ DE MIGUEL-LÓPEZ, Juan Antonio SALMERÓN-AROCA, Pedro MORENO-ABELLÁN

This study analyses how children perceive older people. The aim is to identify the early emergence of ageist stereotypes in order to inform the design of preventive interventions in schools. A mixed-methods design was employed for this study, which involved a sample of 277 participants aged between 4 and 6 years (M = 4.87, SD = 0.77), 45.1 per cent of whom were girls. The Spanish version of the Young Children’s Views of Older People (YCVOP) questionnaire was used, supplemented by an open-ended question designed to …

31.08.2026journal-article

Ethik in der Medizin

Vulnerabilität in stationären Wohnformen für Menschen mit Behinderung am Beispiel der Empfängnisverhütung

Fenja Caris, Solveig Lena Hansen

Zusammenfassung Die Empfängnisverhütung bei Frauen mit intellektueller Beeinträchtigung ist ein mit ethischen Konflikten behaftetes Thema. Bisherige Interventionen beschränken sich auf die Individualebene. Damit wird die Verantwortung für das Thema bei den betroffenen Frauen bzw. ihrem Umfeld verortet, wodurch strukturelle und kontextbezogene Faktoren häufig außer Acht gelassen werden. Im Hinblick auf die Empfängnisverhütung ist das Wohnen ein Kontext, dessen Strukturen die Vulnerabilität von Frauen beeinflussen kö …

31.08.2026journal-article

BMC Geriatrics

How joint trajectories of frailty and cognitive decline impact hospitalization and mortality: evidence from the Korean longitudinal study of aging 2006–2020

Sumi Lee

Abstract Background Frailty and cognitive decline are major public health concerns that often progress together in older adults. However, previous studies have generally examined these two conditions separately and have tended to overlook the dynamic nature of frailty. This study analyzed how joint trajectories of frailty and cognitive decline influence the risks of hospitalization and mortality. Methods This secondary data analysis used data from the Korean Longitudinal Study of Aging from 2006 to 2020. The study …

31.08.2026journal-article

Revista ft

Gestão do desempenho das pessoas nas organizações.

Constantino Eduardo Tchiyaka

This article is the result of an exploratory study grounded in a theoretical literature review, aiming to conduct research on performance management. In addition to presenting the main factors conditioning worker performance and understanding the causes and effects of employee behavior along with its influence on company performance, this project also aimed to provide an overview of the addressed topics and, fundamentally, present the state of the art of performance management in organizations in order to suggest i …