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Are the “Serial 7s” and Spelling Backwards Tasks From the MMSE Comparable in MCI and Dementia?

Edoardo Nicolò Aiello, Giulia De Luca, Arianna Moreschi, Beatrice Curti, Francesco Cazzini, Andrea Cerri, Selene Saba, Valerio Patisso, Alessio Maranzano, Vincenzo Silani, Nicola Ticozzi, Federico Verde, Barbara Poletti

American Journal of Alzheimer's Disease & Other Dementias® · 2026

Vollständiger Abstract

Worum geht es in dieser Arbeit?

We explored the comparability of the “Serial 7s” (S7) and Spelling Backwards (SB) tasks from MMSE in 313 patients with MCI ( N =54) and dementia ( N =259) due to Alzheimer’s disease (AD), frontotemporal lobar degeneration, Lewy body disease, non-AD degenerative (NADD), chronic cerebrovascular disease (CVD) or mixed (AD+CVD) etiologies. Although the two tasks were significantly associated with each other ( r =.54), a two one-sided test revealed that they were not statistically equivalent. Consistently, a linear mixed model testing the effect of task Type (S7 vs. SB) net of demographics, disease duration, disease severity and etiology revealed that the S7 condition was more difficult to be performed ( M =1.69) than the SB one ( M =3.03). Hence, in MCI and dementia due to chronic-degenerative etiologies, the S7 and the SB tasks from the MMSE are not comparable. Users should exert caution when qualitatively interpreting examinees’ attentional levels based on these tasks.

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Publikationsdaten

Autor:innen
Edoardo Nicolò Aiello, Giulia De Luca, Arianna Moreschi, Beatrice Curti, Francesco Cazzini, Andrea Cerri, Selene Saba, Valerio Patisso, Alessio Maranzano, Vincenzo Silani, Nicola Ticozzi, Federico Verde, Barbara Poletti
Quelle
American Journal of Alzheimer's Disease & Other Dementias®
Publikation
2026-01-01
Band / Ausgabe
Nicht angegeben
Seiten
Nicht angegeben
ISSN / ISBN
1533-3175, 1938-2731
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Edoardo Nicolò Aiello, Giulia De Luca, Arianna Moreschi, Beatrice Curti, Francesco Cazzini, Andrea Cerri, Selene Saba, Valerio Patisso, Alessio Maranzano, Vincenzo Silani, Nicola Ticozzi, Federico Verde, Barbara Poletti (2026). Are the “Serial 7s” and Spelling Backwards Tasks From the MMSE Comparable in MCI and Dementia?. American Journal of Alzheimer's Disease & Other Dementias®. https://doi.org/10.1177/15333175261449026
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