Frontiers in Dental Medicine
Diagnostic performance of artificial intelligence in oral squamous cell carcinoma detection: a higher-order evidence synthesis through umbrella review and meta-meta-analysis
Background The integration of AI into oral squamous cell carcinoma (OSCC) diagnostics is a major milestone for digital dentistry and computational pathology, enabling faster, highly accurate detection. While numerous systematic reviews have attempted to synthesize this burgeoning evidence, their conclusions remain discordant and methodological quality varies substantially. Aim This umbrella review undertakes a rigorous synthesis of systematic review evidence to establish definitive accuracy metrics, evaluate method …