Alle Themen: neue Gesundheitspublikationen – Seite 95

03.09.2026journal-article

Limaq

Cultivar la Ciudad: huertos urbanos y la coproducción del espacio público en Latinoamérica

Adriana Sansao Fontes, Maini De Oliveira Perpétuo, Giovana Bulcão Leal, Amanda Trainini Baptista, Beatriz Mangabeira Cunha, Ilan Rzetelna

Este artículo investiga la agricultura urbana como práctica de coproducción del espacio público en contextos de inseguridad alimentaria y exclusión socioespacial en Latinoamérica. Desde un enfoque cualitativo y comparativo, analiza tres casos emblemáticos —La Habana, Quito y Río de Janeiro— en los que los huertos urbanos surgieron como respuestas comunitarias a crisis y posteriormente fueron institucionalizados como políticas públicas. El estudio examina su potencial para activar espacios urbanos ociosos, ampliar á …

03.09.2026journal-article

Journal of Clinical Medicine

Updating the Prevalence of H. pylori and Extensive Precancerous Lesions in the Stomach: Results of a Multicenter, Endoscopic Study

Angelo Zullo, Giulio Cozza, Guido Manfredi, Saverio Alicante, Andrea Mega, Eugenio Marconato, Salvatore Russo, Benedetta Toro, Luca De Luca, Marco Magistroni, Bastianello Germanà, Nunzia Russo, Elisabetta Martinelli, Alessandra Loiodice, Dino Vaira, Giulia Fiorini, Giuseppe Scaccianoce, Berardino D’Ascoli, Roberto Vassallo, Vincenzo De Francesco, Gianluca Esposito, Irene Ligato, Marcello Maida, Federico Bonomo, Giovanna Ruggiero, Andrea Boccuto, Francesca Galeazzi, Anna Ros, Angelo Milano, Rachele Ciccocioppo, Fabio Monica, Marco Sartori, Giulia Leonardi, Raffaele Manta

Background/Objectives: H. pylori is the main preventable risk factor for gastric cancer through the development of extensive precancerous lesions, namely mucosal atrophy and intestinal metaplasia. Methods: This multicenter, nationwide study enrolled consecutive patients who underwent their first upper gastrointestinal endoscopy with standard biopsies. Clinical, endoscopic and histological data were gathered for statistical analysis using both univariate and multivariate analyses. Results: Data from 775 patients wer …

03.09.2026journal-article

American Journal of Audiology

Understanding Hearing Health Care Choices and Customer Archetypes in an Era of Over-the-Counter Hearing Aids

Jasleen Singh, Sumitrajit Dhar

Purpose: The purpose of the study was to identify factors influencing consumer choice toward hearing health care (HHC) delivery pathway (provider-driven vs. over-the-counter [OTC] hearing aids) and to characterize customer archetypes. A secondary purpose was to evaluate shifts in consumer choices and archetypes in light of the recent availability of OTC hearing aids. Method: A 27-item survey, adapted from prior work, was administered via Qualtrics Research Panels to over 1,000 U.S. residents aged 50 years and older …

03.09.2026journal-article

JAMA Network Open

Large Language Models and Adverse Event Detection Within Immunotherapy Clinical Trials

Marianna V. Elia, Isabel D. Friesner, Daniel Kwon, Lisa Ni, Sumi Sinha, Yuta Ishiyama, Travis Zack, Mark Bridge, Lawrence Fong, Julian C. Hong

This comparative effectiveness study examines the ability of a large language model vs human reviewer consensus to identify adverse events from encounter notes from 4 randomized clinical trials.

03.09.2026journal-article

Journal of Addiction Medicine

Impact of Addiction Consult Service on Alcohol Use Disorder Medications and Postdischarge Outcomes

Thomas J. Reese, Kristopher A. Kast, David Marcovitz, Clayton Korson, Hilary A. Tindle, Sahit N. Menon, Ashley A. Leech, Lisa Stewart-Kast, Adam Wright, Mauli V. Shah, Amanda von Horn

Objectives: This study aims to evaluate the association between Addiction Consult Service (ACS) involvement and initiation of medication for alcohol use disorder (MAUD), as well as postdischarge outcomes through 90 days, among adults hospitalized with alcohol-related conditions. Methods: We conducted a retrospective cohort study at a large academic medical center from 2018 to 2025. The exposure of interest was receipt of an ACS consultation during hospitalization. Primary outcomes were inpatient MAUD initiation, M …

03.09.2026journal-article

Blood

A novel triple-knockout allogeneic BCMA CAR T-cell therapy (CT0590) for multiple myeloma: preclinical and phase 1 study

Song Jin, Zhaohui Liao, Shuang Yan, Lingzhi Yan, Weiqin Yao, Jingjing Shang, Fang Tang, Ziling Zhu, Depei Wu, Nishanthan Rajakumaraswamy, Yi Luo, Daijing Yuan, Hua Jiang, Zonghai Li, Chengcheng Fu

Abstract Host-versus-graft reaction (HVGR) is a major challenge in allogeneic chimeric antigen receptor (CAR) T-cell therapy. To counter host natural killer (NK) cell attacks, we armored allogeneic, HLA-I–deficient, B-cell maturation antigen (BCMA)–targeting CAR T cells with an NKG2A CAR. In vitro and animal studies demonstrated that allogeneic CAR-NKG2A T cells effectively resisted host NK cell–mediated killing. BCMA and NKG2A dual-targeting allogeneic CAR T cells (CT0590) resisted killing by NK cells and showed r …

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03.09.2026journal-article

Journal of Imaging Informatics in Medicine

Multi-centre Validation of Automated Outer-to-Outer Wall Segmentation of Infrarenal Abdominal Aortic Aneurysms Using a nnU-Net Based Model

Cas H. F. Hendricks, Willemina A. van Veldhuizen, Amin Ranem, Bram Fioole, Rogier H. J. Kropman, Jelmer M. Wolterink, Jean-Paul P. M. de Vries

Abstract Accurate outer-to-outer wall aortic segmentation is essential for abdominal aortic aneurysm (AAA) assessment and endovascular aneurysm repair (EVAR) planning, yet manual segmentation is time-consuming and impractical for routine use. This study aimed to validate a pre-trained open-source nnU-Net–based model for fully automated outer-to-outer wall segmentation of the abdominal aorta in AAA patients. In this retrospective multicentre observational validation study, 75 consecutive AAA patients (25 per centre) …

03.09.2026journal-article

Acta Neurochirurgica

Clinical course of traumatic cerebral venous sinus thrombosis: Insights from a UK major trauma centre

Sheikh Muktadir Bin Momin, Faheem Anwar, Georgina Shallard, Azam Ali Baig, Yousra Rasool, Anam Fatima, Andrew R. Stevens, Philip Ho, Anne Preece, David James Davies, Antonio Belli, Ramesh Chelvarajah, Philip J. O’Halloran

Abstract Background Traumatic venous sinus thrombosis (tCVST) is a recognised complication of traumatic brain injury (TBI), usually secondary to adjacent skull fractures or intracranial haemorrhage. The optimal timing of diagnostic CT venography (CTV) and anticoagulation initiation remains uncertain. Methods A retrospective cohort study was performed at Queen Elizabeth Hospital Birmingham, a UK Major Trauma Centre, including patients aged > 16 years with radiologically-confirmed tCVST between January 2020-December …

03.09.2026journal-article

Journal of Cardiovascular Development and Disease

Sports Cardiology: From Diagnosis to Clinical Management—Towards Individualized Cardiovascular Care Through Exercise

Christos Kourek, Eleftherios Karatzanos, Stavros Dimopoulos

This Special Issue, “Sports Cardiology: From Diagnosis to Clinical Management”, was developed to reflect the expanding scope of sports cardiology, a field that now extends well beyond the assessment of competitive athletes alone [...]

03.09.2026journal-article

Biology

Application of an Index Based on Aquatic Insect Biotic Integrity for River Ecosystem Health Assessment in Haihe River Basin, China

Fanqing Kong, Zhilin Li, Yue Shen, Yanchu Zhao, Yin Hou, Zihang Hu, Shaowei Bian

As critical biological components of freshwater ecosystems, aquatic insects are highly sensitive to cumulative anthropogenic disturbances and can effectively reflect long-term variations in river ecological quality, serving as ideal bioindicators for aquatic ecological monitoring and assessment. However, most existing benthic biotic integrity indices integrate diverse macroinvertebrate groups, which dilute the unique indicative value of aquatic insect communities, and few targeted evaluation systems have been indep …

03.09.2026journal-article

International Journal of Pharmacy Practice

A survey of service provision and use of consultation rooms and clinical records in community pharmacies

Natalie Gauld, Frances Redmond, Arier Lee, Trudi Aspden

Abstract Objectives To examine consultation room use, services delivered, and use of clinical records in New Zealand (NZ) community pharmacies. Methods Community pharmacies were surveyed. Analysis included descriptive statistics, Fisher exact tests, t-tests, and ANOVA. Key findings Of 104 responses (42% response rate), 92.2% had consultation room/s, used on average eight times per day. Most respondents wanted to improve their consultation room. Micro-credentialled services usually used consultation rooms, but some …

03.09.2026journal-article

Medical Care

Patient Outcomes and Nurse Understaffing in For-Profit Hospitals

Matthew D. McHugh, Karen B. Lasater, K. Jane Muir, Angelo Petto, Trissa Lyman, Linda H. Aiken

Background: For-profit hospital ownership has been associated with worse patient outcomes, but the mechanisms remain unclear. Underinvestment in nurse staffing is a plausible pathway linking for-profit ownership to performance. Objectives: To examine whether differences in nurse staffing mediate associations between for-profit hospital ownership and patient, nurse, and hospital outcomes. Design: Cross-sectional study using 2024 data on hospital ownership, registered nurse survey responses, Medicare claims, and Hosp …

03.09.2026journal-article

PLOS Digital Health

Deceptive bias measurement in deep learning: Assessing shortcut reliance in TCGA cancer models

Farnaz Kheiri, Shahryar Rahnamayan, Masoud Makrehchi

Machine learning bias is a persistent challenge because it can create unfair outcomes, limit generalization, and reduce trust in real-world applications. A key source of this problem is shortcut learning, where models exploit signals linked to sensitive attributes, such as the data source or collection site, instead of relying on task-relevant features. To address this, we propose the Deceptive Signal metric, a novel quantitative measure designed to assess the extent of a model’s reliance on hidden shortcuts during …

03.09.2026journal-article

European Journal of Dental Education

Knowledge, Attitude and Perception of Dental Professionals and Students Toward Traditional and Complementary Medicine: A Cross‐Sectional Study

Ayse Tas, Nelli Agbulut

ABSTRACT Purpose/Objectives Traditional and Complementary Medicine (TCM) has gained global recognition, and Turkey officially regulates 15 TCM practices within its healthcare system. Despite increasing interest, the knowledge and attitudes of dental professionals and students remain underexplored; this study aims to evaluate knowledge, attitudes, and perceptions toward TCM among dental students, general practitioner dentists (GPDs), and dental specialists in Turkey. Methods A cross‐sectional questionnaire was condu …

03.09.2026journal-article

Asian Journal of Agricultural Extension, Economics & Sociology

Governance Conditions and Local Barriers to Artificial Intelligence in Agricultural Extension and Rural Public Services in Yongding District, China

Han Su, Jing Liao

Aims: This study examines how grassroots and local actors perceive AI-enabled agricultural extension and rural public services in Yongding District, Longyan City, Fujian Province, China, with particular attention to perceived opportunities, implementation barriers, and governance conditions. Study Design: A qualitative case-study design was used, incorporating thematic analysis with descriptive frequency coding. Place and Duration of Study: The primary study area was Yongding District, Longyan City, Fujian Province …

03.09.2026journal-article

Cancers

Clinical Applicability of the WHO Reporting System for Axillary Lymph Node Fine-Needle Aspiration in Invasive Breast Carcinoma

Mariana Canepa, Allison Chang, Stephanie L. Graff, Yihong Wang

Background: Axillary lymph node (ALN) fine-needle aspirations (FNAs) can guide the next steps in the management of patients with invasive breast carcinoma (BC). The objective is to evaluate the diagnostic performance of ALN FNA in the detection of metastatic breast carcinoma. Methods: We evaluated ALN FNAs from 2020 to 2024 to determine the risk of malignancy (ROM) of different cytologic diagnostic categories using a general WHO cytology reporting system framework (insufficient, benign, atypical, suspicious, and ma …

03.09.2026journal-article

Military Medicine

Past-Year Co-Use of Alcohol and Opioid and Suicidal Behaviors in U.S. Adults with Prior Military Service

Ava C Santiago, Anwar E Ahmed, Jangho Yoon, Karl C Alcover

Abstract Introduction Alcohol use and opioid use independently increase the risk of suicidal behaviors. These substances are also frequently used concurrently, yet the extent to which their co-use contributes to suicidal behaviors at the population level remains insufficiently understood. This gap is particularly relevant among adults with prior military service, who experience elevated burdens of chronic pain, opioid exposure, and mental health comorbidities. We therefore examined whether past-year alcohol–opioid …

03.09.2026journal-article

Healthcare

The Correlation of Psychological Symptoms, Quality of Life and Resilience in Patients with Recurrent Non-Melanoma Skin Cancer

Goran Šimić, Tomislav Sušac, Josip Lesko, Ana Dugandžić Šimić, Vedran Markotić, Dragan Babić

Recurrent non-melanoma skin cancer (NMSC) may be accompanied by cosmetic, functional, and emotional consequences. Aims: To examine associations among psychological symptoms, quality of life, resilience, and religiosity and to compare psychological outcomes between patients treated once and patients with recurrent facial NMSC. Methods: This cross-sectional study included 160 patients after surgery for facial NMSC (63 treated once and 97 with recurrent disease). Data were collected with a sociodemographic questionnai …

03.09.2026journal-article

Frontiers in Public Health

The effectiveness of the intervention model based on cognitive behavioral therapy in reducing risky sexual behaviors among MSM

Xiaochen Xiang, Xiaobing Zhai, Yumeng Lei, Jialu Feng, Qiang Wang

Methods Based on CBT theory and the Internet, we established an intervention model targeting high-risk sexual behavior patterns in MSM. We then conducted a randomized controlled trial ( n = 50) to assess the impact of the CBT-based intervention on high-risk sexual behaviors and gut microbiota changes in this population. Results Prior to the implementation of the intervention, 44% of the participants engaged in high-risk behaviors despite having better cognitive levels. However, preliminary findings from post-interv …

03.09.2026journal-article

Frontiers in Medicine

Intravitreal exposure to the SARS-CoV-2 spike protein is associated with aggravated retinal lesions in a murine model of central retinal vein occlusion

Siyi Liu, Zhihui Zhang, Yumin Zhang, Xinglong Wang, Yibin Yu, Yunshan Cao, Yan Zhang

Purpose To explore effects of SARS-CoV-2 ocular infection on severity of central retinal vein occlusion (CRVO) and the associated cellular and molecular clues. Methods The spike protein (SP) was intravitreally administered to mimic the pathological process of SARS-CoV-2 ocular infection. Eight-week-old C57BL/6 male mice were randomly divided into 5 groups: normal control (NOR), CRVO, 0.2 SP + CRVO, 0.4 SP + CRVO, and 0.8 SP + CRVO groups. The CRVO group was intravitreally injected with phosphate-buffered saline, an …

03.09.2026journal-article

Frontiers in Digital Health

Co-constructing stories with patients with heart failure to envision future remote care possibilities: a qualitative interview and sketching study

Wessel W. Nieuwenhuys, Hannah C. van Iterson, Jeroen A. A. van de Pol, Mayke M. C. J. van Leunen, Ignace L. J. de Lathauwer, Mathias Funk, Rong-Hao Liang, Hareld M. C. Kemps

Introduction Although remote patient management (RPM) shows promise for improving chronic heart failure (HF) management, its effectiveness depends on technology acceptance, usability, and patient engagement. However, patients are often involved only after systems are implemented, limiting opportunities to align RPM with their needs. This study explored patients' expectations, wishes, and concerns regarding future RPM using participatory design methods to inform more patient-centred RPM. Methods Patients with HF usi …

03.09.2026journal-article

Frontiers in Immunology

T-cell redirecting therapies in lung cancer - a comprehensive analysis of clinical trials

Jiahe Zhao, Ayrton Bangolo, Lili Zhang, Martin Gutierrez, Miguel Gonzalez-Velez

Lung cancer remains the leading cause of cancer-related mortality worldwide, and despite the transformative impact of immune checkpoint inhibitors (ICIs), primary and acquired resistance, limited efficacy in immune-cold tumors such as extensive-stage small cell lung cancer (ES-SCLC), and the absence of durable responses in a substantial proportion of patients define the unmet need that T cell-redirected therapies aim to address. These strategies engage, engineer, and deliver cytotoxic T cells against tumor cells in …

03.09.2026journal-article

Frontiers in Public Health

Physical exercise therapy for autism spectrum disorder: a scoping review of systematic reviews

Fei Fan, Ji Li, Xuan Zhang, Bo Wang, Zilin Chen, Yuchen Hu, Fei Han

Background Physical exercise therapy (PET) is used as a non-pharmacological intervention for individuals with autism spectrum disorder (ASD). However, the overall evidence landscape remains unclear. Methods This scoping review adhered to the Joanna Briggs Institute methodology and the PRISMA-ScR checklist. Searches were conducted in MEDLINE, EMBASE, Web of Science, and Cochrane Library from database inception to December 4, 2025. Included were systematic reviews that investigated PET for individuals with ASD. Two r …

03.09.2026journal-article

Frontiers in Public Health

The mediating roles of screen time and sleep duration in the association between extracurricular physical activity and visual acuity in primary school students

Jilin Li, Yang Wang, Xuehui Zhang, Ye Chen, Li Xi

Objective This study aimed to examine the association between extracurricular physical activity (EPA) and visual acuity (VA) among primary school students in Macau and investigate the mediating roles of screen time (ST) and sleep duration (SD). Methods A stratified random cluster sampling method was used to recruit primary school students in Macau ( n = 2,098). Data were collected using questionnaire surveys. Pearson correlation analysis and structural equation modeling were conducted. Results EPA, ST, SD, and VA w …

Was ist neu im Gesundheitswesen?

Aktuelle Forschung nach Fachgebiet

Cultivar la Ciudad: huertos urbanos y la coproducción del espacio público en Latinoamérica

Updating the Prevalence of H. pylori and Extensive Precancerous Lesions in the Stomach: Results of a Multicenter, Endoscopic Study

Understanding Hearing Health Care Choices and Customer Archetypes in an Era of Over-the-Counter Hearing Aids

Large Language Models and Adverse Event Detection Within Immunotherapy Clinical Trials

Impact of Addiction Consult Service on Alcohol Use Disorder Medications and Postdischarge Outcomes

A novel triple-knockout allogeneic BCMA CAR T-cell therapy (CT0590) for multiple myeloma: preclinical and phase 1 study

Multi-centre Validation of Automated Outer-to-Outer Wall Segmentation of Infrarenal Abdominal Aortic Aneurysms Using a nnU-Net Based Model

Clinical course of traumatic cerebral venous sinus thrombosis: Insights from a UK major trauma centre

Sports Cardiology: From Diagnosis to Clinical Management—Towards Individualized Cardiovascular Care Through Exercise

Application of an Index Based on Aquatic Insect Biotic Integrity for River Ecosystem Health Assessment in Haihe River Basin, China

A survey of service provision and use of consultation rooms and clinical records in community pharmacies

Patient Outcomes and Nurse Understaffing in For-Profit Hospitals

Deceptive bias measurement in deep learning: Assessing shortcut reliance in TCGA cancer models

Knowledge, Attitude and Perception of Dental Professionals and Students Toward Traditional and Complementary Medicine: A Cross‐Sectional Study

Governance Conditions and Local Barriers to Artificial Intelligence in Agricultural Extension and Rural Public Services in Yongding District, China

Clinical Applicability of the WHO Reporting System for Axillary Lymph Node Fine-Needle Aspiration in Invasive Breast Carcinoma

Past-Year Co-Use of Alcohol and Opioid and Suicidal Behaviors in U.S. Adults with Prior Military Service

The Correlation of Psychological Symptoms, Quality of Life and Resilience in Patients with Recurrent Non-Melanoma Skin Cancer

The effectiveness of the intervention model based on cognitive behavioral therapy in reducing risky sexual behaviors among MSM

Intravitreal exposure to the SARS-CoV-2 spike protein is associated with aggravated retinal lesions in a murine model of central retinal vein occlusion

Co-constructing stories with patients with heart failure to envision future remote care possibilities: a qualitative interview and sketching study

T-cell redirecting therapies in lung cancer - a comprehensive analysis of clinical trials

Physical exercise therapy for autism spectrum disorder: a scoping review of systematic reviews

The mediating roles of screen time and sleep duration in the association between extracurricular physical activity and visual acuity in primary school students