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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Frontiers in Public Health

Factors associated with social support among older inpatients with schizophrenia: a cross-sectional study from a tertiary psychiatric hospital in Guangzhou, China

Jinrong Li, Junrong Ye, Jiao Chen, Dingjie Liu, Xueyu Zheng, Yulin Li, Na Ma, Yuhan Zhang, Yanheng Wei, Tian Zhou, Jianxiong Guo, Aixiang Xiao

Background Older inpatients with schizophrenia have lower social support levels that may affect clinical outcomes, yet the associated factors in this population remain underexplored. Objective To explore the factors associated with social support in older inpatients with schizophrenia. Methods A cross-sectional study was conducted among 204 inpatients with schizophrenia recruited from a tertiary psychiatric hospital in Guangzhou, China, between February 2023 and December 2024. Social support and its three dimension …

03.09.2026journal-article

Frontiers in Medicine

Analytical validation of capillary blood Krebs von den Lungen-6 measurement using a high- sensitivity chemiluminescent immunoassay in pediatric patients

Chengyuan Zhao, Lingyun Shi, Dan Cao, Xianwei Zhang, Tong Cao

Objective This study evaluates the analytical validity of capillary blood for Krebs von den Lungen-6 (KL-6) detection using a high-sensitivity chemiluminescent immunoassay (CLIA) on the C5000 analyser and assesses agreement between capillary plasma and venous plasma measurements, with emphasis on methodological feasibility rather than clinical diagnostic performance. Methods Analytical performance was assessed in terms of repeatability, accuracy and method comparison. Precision was evaluated using pediatric venous …

03.09.2026journal-article

Liaquat National Journal of Primary Care

Neuroprotective Properties of Lactobacillus plantarum: Bridging Gut Health and Cognition

Deepali Deepali, Pavan Kumar Chikkavalli Muddanna, Dhanush Hulikere Koppalu Devaraju, Dhanya Kellur Nagaraja, Mahendra Kumar Betur Jayappa

A growing body of research demonstrates that the composition of the gut microbiome influences central nervous system function through the gut-brain axis, an essential link in neurophysiological processes. Lactobacillus plantarum, a widely studied probiotic, exhibits multiple neuroprotective mechanisms that support its potential as a psychobiotic. This review synthesizes current preclinical and clinical evidence regarding the effects of L. plantarum on cognitive function, neuroinflammation, oxidative stress, and neu …

03.09.2026journal-article

Demidov Law Journal

Заведомость как обязательный признак преступлений, связанных с публичным распространением ложной информации: актуальные проблемы применения статей 207.1-207.3 УК РФ

Nikhad V. Dunyamalyev

This article is devoted to a comprehensive study of the element of «deliberateness» in crimes related to the public dissemination of false information (Articles 207.1-207.3 of the Russian Criminal Code). An analysis of various doctrinal approaches to the legal nature of deliberateness is conducted, examining it as a special technique of legislative drafting. Particular attention is paid to the analysis of current judicial practice, which reveals significant heterogeneity in the methodological approaches of judicial …

03.09.2026journal-article

Clinical Anatomy

Accuracy of Freehand Versus Navigated External Ventricular Drainage and Comparison of Insertion Trajectories: A Systematic Review and Meta Analysis

Adam Sedlák, Martin Černý, Adam Koza, David Kachlík, David Netuka, Lea Mladá, Miroslav Žáček, Martin Májovský

ABSTRACT The external ventricular drainage is a routine neurosurgical procedure, most often performed by cannulating the frontal horn of the lateral ventricle. Various entry points and insertion trajectory definitions have been proposed; nevertheless, it remains unclear which approach yields the highest success rate. Furthermore, in contemporary clinical practice, generally more efficient navigated ventriculostomies are available. This study aims to compare success rates between freehand and navigated procedures an …

03.09.2026journal-article

Intelligent Data Analysis: An International Journal

A two-step feature selection using permutation based feature importance and wrapper-based bio-inspired algorithms for classifying clinical dataset

Kochukrishnan Sivendran Navin, Khanna Harichandran Nehemiah, Nancy Jane Yesudhas, Kannan Arputharaj

Abstract The proposed framework aims to address the challenge of high-dimensional, noisy, irrelevant, and redundant features in clinical datasets by using a two-step feature selection approach. The first step involves a wrapper-based method for calculating the Permutation Based Feature Importance (PBFI) score using the Support Vector Machine (SVM) classifier. The second step employs three wrapper-based bio-inspired optimization algorithms, namely Harris Hawk Optimization (HHO), Binary Grasshopper Optimization (BGOA …

03.09.2026journal-article

Clinical Rehabilitation

Adapted cardiac rehabilitation for individuals after stroke and transient ischaemic attack: A scoping review

Peter Hartley, Katie Bond, Claire Brown, Faye Forsyth, Jennifer Harrison, Isla Kuhn, Gemma Smith, Lydia Wiffen, Joanne McPeake

Objective To summarise evidence on the intervention design, safety, feasibility, acceptability, and effectiveness of a cardiac rehabilitation-based intervention for people who have had a stroke or transient ischaemic attack (TIA). Data sources Medline, PsycINFO, Embase, and CINAHL were searched between inception and 2026 for experimental or observational English-language studies that evaluated a cardiac rehabilitation-based intervention delivered to people with a history of stroke or TIA. Review methods Data were s …

03.09.2026journal-article

Proceedings of the Human Factors and Ergonomics Society Annual Meeting

Iterative Design of a Prototype Patient Tray for Unstable Spines

Yifan Li, Eve Shikanov, Loryn Hovelson, Darcy R. Erickson, Petrine Cerri, M. Susan Hallbeck, Gerald Malagrino

Hospital practitioners have a high prevalence of work-related musculoskeletal disorders due to manual patient transfers. Reducing patient transfers can improve safety for staff and patients, especially those with unstable spines. A study at our academic hospital with the Safe TrAnsfer Tray prototype (STAT Tray V1) found transfers could be reduced to the two unavoidable transfers at the beginning and end of care. Surveys from 37 practitioners identified clinical challenges. User feedback informed design requirements …

03.09.2026journal-article

Journal of Embedded Systems, Security and Intelligent Systems

Internet of Things-Based Decision Support System for Toddler Health Using Mamdani Fuzzy Logic

I Gede Wiryawan, Yogiswara, Beni Widiawan, Lalitya Nindita Sahenda, Nanda Raditya Akbar

Purpose – This study develops and evaluates an Internet of Things-based decision support system using Mamdani fuzzy logic for the early identification of febrile seizure risk in toddlers. The system integrates continuous body-temperature and heart-rate monitoring to provide automated risk classification and real-time warning information. Design/methods/approach – The prototype combines an Arduino Uno, a GY-906 non-contact temperature sensor, a pulse sensor, an ESP8266 communication module, and a web-based monitorin …

03.09.2026journal-article

Drugs in Context

Efficacy and safety of an Ayurvedic Menohelp syrup in the management of heavy menstrual bleeding (menorrhagia): an open-label clinical study

Kamini Dhiman, Pradeep Kumar Prajapati, Deepika Gopal, Ashutosh Gautam, Rajat Singal

Background: Heavy menstrual bleeding (HMB) is a common gynaecological condition that significantly affects the quality of life and daily functioning amongst women of reproductive age. In Ayurveda, this condition is described under the category of Asrigdara. Menohelp Syrup, an Ashoka (Saraca asoca)-based Ayurvedic formulation, is traditionally used for the management of HMB. This open-label study evaluated the efficacy and safety of Menohelp Syrup in women with HMB. The study aimed to assess reductions in menstrual …

03.09.2026journal-article

Journal of Addiction Medicine

Impact of Addiction Consult Service on Alcohol Use Disorder Medications and Postdischarge Outcomes

Thomas J. Reese, Kristopher A. Kast, David Marcovitz, Clayton Korson, Hilary A. Tindle, Sahit N. Menon, Ashley A. Leech, Lisa Stewart-Kast, Adam Wright, Mauli V. Shah, Amanda von Horn

Objectives: This study aims to evaluate the association between Addiction Consult Service (ACS) involvement and initiation of medication for alcohol use disorder (MAUD), as well as postdischarge outcomes through 90 days, among adults hospitalized with alcohol-related conditions.​ Methods: We conducted a retrospective cohort study at a large academic medical center from 2018 to 2025. The exposure of interest was receipt of an ACS consultation during hospitalization. Primary outcomes were inpatient MAUD initiation, M …

03.09.2026journal-article

Cancers

Clinical Applicability of the WHO Reporting System for Axillary Lymph Node Fine-Needle Aspiration in Invasive Breast Carcinoma

Mariana Canepa, Allison Chang, Stephanie L. Graff, Yihong Wang

Background: Axillary lymph node (ALN) fine-needle aspirations (FNAs) can guide the next steps in the management of patients with invasive breast carcinoma (BC). The objective is to evaluate the diagnostic performance of ALN FNA in the detection of metastatic breast carcinoma. Methods: We evaluated ALN FNAs from 2020 to 2024 to determine the risk of malignancy (ROM) of different cytologic diagnostic categories using a general WHO cytology reporting system framework (insufficient, benign, atypical, suspicious, and ma …

03.09.2026journal-article

Physics in Medicine & Biology

A physics-informed decomposition network for carbon ion radiotherapy dose monitoring: a proof-of-concept study

Xin-Yu Hu, Yan Li, Wei-Guang Li, Yu-Ying Yin, Chao Yang, Cheng Chang, Ming-Qing Wang, Kai-Wen Li, Xueying Yang, Li-Sheng Geng

Abstract Objective. In-beam positron emission tomography (PET) provides a promising strategy for dose monitoring in carbon ion radiotherapy (CIRT), but accurate dose prediction remains difficult due to the complex, nonlinear relationship between positron-emitter activity and physical dose deposition. This proof-of-concept study aimed to improve activity-to-dose mapping by developing decomposition-based deep learning frameworks with auxiliary physical supervision. Approach. Idealized Monte Carlo (MC) simulations wer …

03.09.2026journal-article

PLOS Digital Health

Deceptive bias measurement in deep learning: Assessing shortcut reliance in TCGA cancer models

Farnaz Kheiri, Shahryar Rahnamayan, Masoud Makrehchi

Machine learning bias is a persistent challenge because it can create unfair outcomes, limit generalization, and reduce trust in real-world applications. A key source of this problem is shortcut learning, where models exploit signals linked to sensitive attributes, such as the data source or collection site, instead of relying on task-relevant features. To address this, we propose the Deceptive Signal metric, a novel quantitative measure designed to assess the extent of a model’s reliance on hidden shortcuts during …

03.09.2026journal-article

Blood

Niche-targeted therapy via YAP/TAZ activation enhances hematopoietic regeneration

Shun Uemura, Masayuki Yamashita, Takako Yokomizo-Nakano, Ayako Aihara, Takumi Iwawaki, Shuhei Koide, Yaeko Nakajima-Takagi, Motohiko Oshima, Yoshiki Omatsu, Yuki Matsumoto, Yoshiaki Kubota, Bahityar Rahmutulla, Atsushi Kaneda, Miki Nishio, Akira Suzuki, Takashi Nagasawa, Kenta Kagaya, Taito Nishino, Atsushi Iwama

Abstract The distinctive milieu of the bone marrow (BM), known as the BM niche, supports hematopoietic stem cells (HSCs) and serves as a foundation for hematopoietic regeneration. Myeloablative stress disrupts not only hematopoietic stem and progenitor cells but also essential BM niche components, including endothelial cells (ECs) and mesenchymal stromal cells (MSCs); disruption of the latter impairs efficient hematopoietic recovery. However, therapeutic strategies targeting niche restoration remain largely underde …

03.09.2026journal-article

INTERNATIONAL JOURNAL OF HEALTH AND PHARMACEUTICAL RESEARCH

Antibiotic Prescribing Behaviour Among Different Healthcare Cadres: Evidence from Primary Health Care Facilities in Osogbo, Nigeria

Kayode Samuel Ayomide

Background: Inappropriate antibiotic prescribing in primary healthcare settings is a major driver of antimicrobial resistance (AMR), particularly in low- and middle-income countries. In Osogbo Local Government Area, Osun State, Nigeria, primary health centres serve as the primary entry point for infectious disease management, yet prescribing practices often deviate from evidence based guidelines due to systemic constraints. Objective: This review synthesises evidence on antibiotic prescribing behaviours among healt …

03.09.2026journal-article

Journal of Clinical Medicine

Updating the Prevalence of H. pylori and Extensive Precancerous Lesions in the Stomach: Results of a Multicenter, Endoscopic Study

Angelo Zullo, Giulio Cozza, Guido Manfredi, Saverio Alicante, Andrea Mega, Eugenio Marconato, Salvatore Russo, Benedetta Toro, Luca De Luca, Marco Magistroni, Bastianello Germanà, Nunzia Russo, Elisabetta Martinelli, Alessandra Loiodice, Dino Vaira, Giulia Fiorini, Giuseppe Scaccianoce, Berardino D’Ascoli, Roberto Vassallo, Vincenzo De Francesco, Gianluca Esposito, Irene Ligato, Marcello Maida, Federico Bonomo, Giovanna Ruggiero, Andrea Boccuto, Francesca Galeazzi, Anna Ros, Angelo Milano, Rachele Ciccocioppo, Fabio Monica, Marco Sartori, Giulia Leonardi, Raffaele Manta

Background/Objectives: H. pylori is the main preventable risk factor for gastric cancer through the development of extensive precancerous lesions, namely mucosal atrophy and intestinal metaplasia. Methods: This multicenter, nationwide study enrolled consecutive patients who underwent their first upper gastrointestinal endoscopy with standard biopsies. Clinical, endoscopic and histological data were gathered for statistical analysis using both univariate and multivariate analyses. Results: Data from 775 patients wer …

03.09.2026journal-article

European Journal of Dental Education

Knowledge, Attitude and Perception of Dental Professionals and Students Toward Traditional and Complementary Medicine: A Cross‐Sectional Study

Ayse Tas, Nelli Agbulut

ABSTRACT Purpose/Objectives Traditional and Complementary Medicine (TCM) has gained global recognition, and Turkey officially regulates 15 TCM practices within its healthcare system. Despite increasing interest, the knowledge and attitudes of dental professionals and students remain underexplored; this study aims to evaluate knowledge, attitudes, and perceptions toward TCM among dental students, general practitioner dentists (GPDs), and dental specialists in Turkey. Methods A cross‐sectional questionnaire was condu …

03.09.2026journal-article

JAMA Network Open

Large Language Models and Adverse Event Detection Within Immunotherapy Clinical Trials

Marianna V. Elia, Isabel D. Friesner, Daniel Kwon, Lisa Ni, Sumi Sinha, Yuta Ishiyama, Travis Zack, Mark Bridge, Lawrence Fong, Julian C. Hong

This comparative effectiveness study examines the ability of a large language model vs human reviewer consensus to identify adverse events from encounter notes from 4 randomized clinical trials.

03.09.2026journal-article

Journal of Minimal Access Surgery

Acute appendicitis in a patient with obstructed hemivagina and ipsilateral renal anomaly syndrome: Diagnostic overshadowing in recurrent pelvic pain

Rafique Umer Harvitkar, Neriah Mangion, Ioannis Hannadjas, Seshu Kumar Bylapudi, Nida Khan

Abstract Herlyn–Werner–Wunderlich syndrome, also known as obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome, is a rare congenital Müllerian duct anomaly, occurring in approximately 1 in 1,000,000 females. It is characterised by a triad of uterine didelphys, obstructed hemivagina and ipsilateral renal agenesis. Patients typically present with chronic pelvic pain, dysmenorrhea and endometriosis, which can lead to diagnostic bias and the misattribution of all pelvic pain to their underlying gynaeco …

03.09.2026journal-article

Limaq

Cultivar la Ciudad: huertos urbanos y la coproducción del espacio público en Latinoamérica

Adriana Sansao Fontes, Maini De Oliveira Perpétuo, Giovana Bulcão Leal, Amanda Trainini Baptista, Beatriz Mangabeira Cunha, Ilan Rzetelna

Este artículo investiga la agricultura urbana como práctica de coproducción del espacio público en contextos de inseguridad alimentaria y exclusión socioespacial en Latinoamérica. Desde un enfoque cualitativo y comparativo, analiza tres casos emblemáticos —La Habana, Quito y Río de Janeiro— en los que los huertos urbanos surgieron como respuestas comunitarias a crisis y posteriormente fueron institucionalizados como políticas públicas. El estudio examina su potencial para activar espacios urbanos ociosos, ampliar á …

03.09.2026journal-article

International Journal of Computer Assisted Radiology and Surgery

Anticipating the hospital of the future: stakeholder perspectives on 6G technology requirements in health care

Anna Schatz, Matthias Rüb, Henriette Hegermann, Meike Hiddemann, Dario Wieschebrock, Dominik Stegemann, Jan Herbst, Christoph Lipps, Clemens Möllenhoff, Thomas Petzold, Ralf Irmer, Friedrich Köhler, Max Rockstroh, Tobias Pabst, Thomas Neumuth, Hans D. Schotten, Sascha Treskatsch

Abstract Purpose The ongoing 6G standardization process is largely driven by technical advancements, but with limited consideration of sector-specific needs, particularly in health care. The current scientific literature primarily focuses on technical aspects, offering minimal empirical input from healthcare professionals, patient representatives, or medical device manufacturers. This neglects clinical acceptance and applicability as a critical factor in technology adoption. The objective of this study is to explor …

03.09.2026journal-article

American Journal of Audiology

Understanding Hearing Health Care Choices and Customer Archetypes in an Era of Over-the-Counter Hearing Aids

Jasleen Singh, Sumitrajit Dhar

Purpose: The purpose of the study was to identify factors influencing consumer choice toward hearing health care (HHC) delivery pathway (provider-driven vs. over-the-counter [OTC] hearing aids) and to characterize customer archetypes. A secondary purpose was to evaluate shifts in consumer choices and archetypes in light of the recent availability of OTC hearing aids. Method: A 27-item survey, adapted from prior work, was administered via Qualtrics Research Panels to over 1,000 U.S. residents aged 50 years and older …

03.09.2026journal-article

BMC Medical Education

Embedding digital health education into pre-registration health degrees: a pilot evaluation of a train-the-trainer toolkit

Leanna Woods, Kerryn Butler-Henderson, Stephen Guinea, Melanie Haines, Samantha Robertson, Sophie Macklin, Melanie Kam, Clair Sullivan

Abstract Background A digitally-literate and future-ready healthcare workforce is essential to realise the benefits of digital health and address critical healthcare challenges. Embedding digital health content into health degree curricula is a strategic priority, yet integration is hindered by the absence of standardised, professionally endorsed curriculum and limited educator expertise. Following development of an educator toolkit, this pilot evaluation study aimed to explore: “How do educators and academic leade …