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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
02.09.2026journal-article

Journal of Clinical Medicine

Sex Bias in the Clinical Diagnosis of ADHD: A Critical Review

Farzad Salehpour, Francisco Gonzalez-Lima

Background: Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder that manifests differently across sexes, potentially impacting symptomatology, diagnosis, and treatment. Nevertheless, these legitimate sex differences in ADHD are further shaped by multiple sources of bias that distort prevalence estimates and clinical recognition. Methods: This critical review synthesizes evidence on a variety of factors, including sampling bias, referral bias, DSM criteria, and diagnostic overs …

02.09.2026journal-article

Journal of Bone and Joint Surgery

Changes in the Management of Periprosthetic Joint Infection Over the Past 50 Years

Armita Armina Abedi, Ghazal Pourbozorg, Michael Abdou, Amir Human Hoveidaei, Javad Parvizi, Mustafa Citak

➢ Periprosthetic joint infection (PJI) remains a major complication of joint arthroplasty, associated with morbidity and health-care burden. Although room for progress remains, the management of PJI has evolved over the past 50 years from empiric, procedure-centered approaches to structured, evidence-based, and biologically informed strategies. ➢ This article summarizes key developments in the prevention, diagnosis, and treatment of PJI, driven by advances across multiple clinical and scientific subspecialties. ➢ D …

02.09.2026journal-article

PeerJ

Molecular characterization of Klebsiella pneumoniae isolated from different clinical sources in Eastern and Western Regions of Saudi Arabia Tertiary Hospitals

Zahra ALBrahim, Nasreldin Elhadi, Faye Aldehalan, Asif A. Jiman-Fatani, Dalya M. Attallah

Introduction The prevalence of extensively drug-resistant (XDR) and multidrug-resistant (MDR) strains worldwide has limited the ability of antimicrobial therapy to treat severe bacterial infections. The emergence and rapid global dissemination of carbapenemase-resistant Klebsiella pneumoniae (CRKP) strains occluded the therapeutic use of carbapenems, the last resort of β-lactams. In Saudi Arabia, major outbreaks of carbapenemase-producing Enterobacteriaceae have been reported, with approximately a 90% prevalence ra …

02.09.2026journal-article

The American Journal of Tropical Medicine and Hygiene

Eyelid Verrucous Sporotrichosis Caused by Sporothrix Brasiliensis Mimicking Cutaneous Leishmaniasis and Complicated by Drug–Drug Interaction

Felipe Tavares Rodrigues, Amanda Ribeiro dos Santos, Sandro Rogério de Almeida, Renata Chaves Albuquerque, Regina Casz Schechtman, Sueli Carneiro

ABSTRACT. Sporotrichosis caused by Sporothrix brasiliensis is endemic in Brazil and may present with atypical clinical features. We report a case of verrucous sporotrichosis of the eyelid mimicking cutaneous leishmaniasis in a 28-year-old woman without cat exposure or trauma. Initial diagnostic studies were inconclusive, and prolonged treatment with oral itraconazole failed. Subsequent fungal culture and polymerase chain reaction established the diagnosis. Medication review revealed concomitant pantoprazole use, li …

02.09.2026journal-article

The American Journal of Tropical Medicine and Hygiene

Leprosy, Water, Sanitation, and Hygiene: A Case–Control Study in a Hyperendemic Area of Brazil

Tolulope R. Ojo-Akosile, Lorena B. P. de Oliveira, Rosemary K. e Lima, José A. Ferreira, Julie A. Clennon, Alexandre C. Branco, Erica B. M. Silva, Maria Aparecida de Faria Grossi, Lucia A. O. Fraga, Jessica K. Fairley

ABSTRACT. Viable Mycobacterium leprae has been detected in the environment and there is growing evidence that the environment may play a role in transmission. Our objective, therefore, was to further explore the association of insecure water, sanitation, and hygiene (WASH) and leprosy in a hyperendemic area of Brazil. A case–control study was conducted in eastern Minas Gerais, Brazil, between June 2016 and December 2018. Individuals with newly diagnosed leprosy and controls ages 3 years or older were enrolled. A de …

02.09.2026journal-article

Mathematical Medicine and Biology: A Journal of the IMA

Complex dynamics behavior in a generalized diffusive multiple delays within-host model for HBV infection with capsids and adaptive immune response in a heterogeneous viral environment

Séverin Foko, Jean M-S Lubuma

Abstract In this paper, we investigate the dynamics of a new chronic hepatitis B model through environmental-driven infection in heterogeneous and homogenous space. The model includes spatial diffusion, five time delays, and a general incidence function. The well-posedness of solutions, including the existence of global solutions, uniqueness, non-negativity, ultimate boundedness, is established. The reproduction numbers for virus infection, CTL immune response, antibody immune response, CTL immune competition and a …

02.09.2026journal-article

International Journal of Molecular Sciences

Nanoplate Digital PCR for Identification of α0-Thalassemia (SEA Deletion): Carrier Screening and Possible Application to Prenatal Diagnosis

Apisit Pattrakorn, Supawadee Yamsri, Attawut Chaibunruang, Anupong Pansuwan, Wanicha Tepakhan, Kritsada Singha, Supan Fucharoen, Hataichanok Srivorakun

The Southeast Asian deletion (--SEA), the most prevalent α0-thalassemia mutation in Southeast Asia, is a major target of regional thalassemia prevention programs. Coinheritance of α0-thalassemia with other hemoglobinopathies, particularly hemoglobin E (Hb E), complicates routine hematological screening and requires reliable molecular confirmation. This study developed and validated a duplex nanoplate digital polymerase chain reaction (dPCR) assay for simultaneous identification of the wild-type α-globin and --SEA d …

02.09.2026journal-article

Problems of Gathering Treatment and Transportation of Oil and Oil Products

IMPROVING THE METHOD FOR DETERMINING THE FUEL GAS CONSUMPTION FOR COMPRESSION USING PHYSICALLY MOTIVATED FEATURES

V.O. Smolnikov, D.A. Godovsky

This paper addresses the pressing issue of improving the energy efficiency of gas transportation systems by developing a highly accurate method for predicting fuel gas consumption by gas compressor units at booster compressor stations. To assess the operating efficiency of booster compressor station equip-ment, a method for reliably determining the fuel gas consumption of gas compressor units is required. Traditional methods of standardization and forecasting, based on industry standards, are characterized by signi …

02.09.2026journal-article

Academy for Practical Oncology

A clinical case of performing risk-reducing surgery with simultaneous implant reconstruction with a mutation in the BRCA1 gene

E. M. Kungurtseva, D. A. Ryabchikov, N. V. Chanturiya, A. N. Khakimov, T. T. Khaidarov, E. S. Makarov, M. G. Filippova

The article highlights the issue of the possibility of performing risk-reducing mastectomy as a cancer prevention for hereditary diseases. A review of the scientific literature has been conducted confirming the advantage of this operation. A clinical case of bilateral subcutaneous mastectomy with simultaneous implant reconstruction in the presence of a mutation in the BRCA1 gene is described.

02.09.2026journal-article

British Journal of Haematology

BCMA versus GPRC5D bispecific antibodies in relapsed/refractory multiple myeloma: A systematic review and meta‐analysis guiding treatment selection

Qi Liang, Shutong Liu, Chunhua Li, Zhijian Liang, Lianxin Zhu, Weida Wang, Zhongjun Xia, Limei Zhang, Yang Liang, Yun Wang

Summary Bispecific antibodies (BsAbs) targeting B‐cell maturation antigen (BCMA) or G protein‐coupled receptor, class C, group 5, member D (GPRC5D) represent effective options for relapsed or refractory multiple myeloma (RRMM), yet direct comparative evidence remains limited. We performed a systematic review and meta‐analysis of studies evaluating BCMA‐ or GPRC5D‐targeted BsAbs in RRMM. Thirty studies comprising 3218 patients were included. Random‐effects models were used to pool efficacy and safety outcomes, follo …

02.09.2026journal-article

Periódicos Brasil. Pesquisa Científica

PERFIL SOCIODEMOGRÁFICO, SOROTIPOS E CLASSIFICAÇÃO CLÍNICA DA DENGUE NO ESTADO DE GOIÁS, BRASIL, 2015–2024

Alessandro Cunha Da Silva, Carlos André Dos Santos, Emilly Martins Gomides, Jordana Moura Pelegrine, Lázaro Furtado Carrilho Neto, Tatiane dos Santos Paulinelli Raposo, Toniel Farias Da Silva Junior, Gabriel Silva Vieira, Aline de Cassia Oliveira Castro, Benigno Alberto Moraes da Rocha

Introdução: A dengue representa um grave desafio de saúde pública no Brasil, caracterizando-se por recorrentes surtos epidêmicos influenciados por fatores socioambientais. Objetivos: Analisar o perfil epidemiológico, sociodemográfico e clínico dos casos de dengue notificados no Estado de Goiás de 2015 a 2024. Material e Métodos: Estudo epidemiológico observacional e descritivo, do tipo série temporal ecológica, utilizando dados do SINAN-DATASUS. Foram analisados casos confirmados de dengue em residentes de Goiás, t …

02.09.2026journal-article

IECCMEXICO

Incidental Imaging Findings: Risk Stratification, Timely Diagnosis, and Clinical Decision-Making

Victor Daniel Velandia Ocaña, Juan Pablo Monroy Moreno, Nicolás Camilo Rivera Calvo, Natalia Restrepo Hinestrosa, Luis Roberto Hernández Mercado, Justin Santiago Palacios Moreira, María Fernanda Velásquez Barba, Alexa Fernanda Uriostegui Navarro

Incidental findings in diagnostic imaging have become increasingly frequent due to the widespread use and growing sensitivity of computed tomography, magnetic resonance imaging, ultrasonography, and other imaging modalities. These findings may range from benign abnormalities without clinical consequences to previously unsuspected diseases capable of modifying diagnostic pathways, therapeutic decisions, and patient prognosis. This study analyzed the clinical impact of incidental imaging findings, emphasizing their r …

02.09.2026journal-article

Plastic and Aesthetic Research

Personalized comprehensive rehabilitation for preventing complications after lower eyelid plastic surgery - a case series and technical description

Liping Gao, Wenxue Lei, Kangxia Li, Xi Yuan, Jie Shen, Jiaping Zhang, Xupin Jiang

Lower eyelid ectropion is a clinically and aesthetically significant complication following blepharoplasty and periocular reconstruction. Although surgical correction is well-established, early postoperative nonsurgical interventions remain limited. This case series describes a structured rehabilitation protocol integrating a custom-fabricated low-temperature thermoplastic eyelid splint with targeted physical therapy for early correction and prevention. We enrolled six patients (eight eyelids) with postoperative lo …

02.09.2026journal-article

Physics in Medicine & Biology

Advances in magnetic-based thermometry and temperature mapping

Joana F Soeiro, Gabriela F Resende, Gabriel C Pinto, Nuno J O Silva

Abstract Temperature monitoring plays a critical role in a variety of therapeutic applications, including thermal therapies. Magnetic-based thermometry has emerged as a versatile and promising approach for localized, non-invasive temperature monitoring and mapping in vivo . This review provides an overview of the latest advances in magnetic temperature sensing techniques, with a focus on magnetic resonance imaging (MRI) and magnetic particle imaging (MPI). Established MRI thermometry techniques based on the variati …

02.09.2026journal-article

AIDS

Clinical phenotypes and incidence of acute or recent hepatitis C virus infection and bacterial sexually transmitted infections among MSM with HIV

Juan Berenguer, Pablo Ryan, Luis Ramos-Ruperto, Luz Martín-Carbonero, Leire Pérez-Latorre, Ignacio De Los Santos, Adriana Pinto, María J. Vivancos, Eva Orviz, Beatriz Álvarez, José Sanz, Pilar Ruiz-Seco, Rafael Torres, Marta De Miguel, Herminia Esteban, Inmaculada Jarrín, Salvador Resino, José M. Bellón, Juan González-García

Objective: Risk of acute/recent hepatitis C virus infection (ARHCV) and bacterial sexually transmitted infections (STIs) among MSM (MSM-HIV) is heterogeneous. We aimed to identify clinical phenotypes and assess their association with incident ARHCV and bacterial STIs. Design: A prospective multicenter cohort study. Methods: Between 2022 and 2024, MSM-HIV were recruited from 10 centers in Madrid and followed for 12 months with HCV and bacterial STI screening. App-based questionnaires captured behavioral and mental h …

02.09.2026journal-article

Problems of Gathering Treatment and Transportation of Oil and Oil Products

STUDY OF GLYPHOSATE-CONTAINING HERBICIDES INFLUENCE ON PLANT CULTURES AND SOIL MICROBIOSIS: DESTRUCTIVE POTENTIAL OF SOIL BIOCENOSIS

D.R. Nurtdinova, I.G. Migranova, M.I. Mallyabaeva, T.V. Tyumkina, S.V. Balakireva, V.I. Safarova

The article underlines the influence of different concentrations of glyphosate-containing herbicides on the growth and development of plant objects using the example of corn seedlings of several varieties, as well as the effect of glyphosate on soil microflora, and analyzes the mechanism of glyphosate biodegradation.The aim of this work is to determine the intervarietal differences in the response of cultivated plants to the presence of glyphosate in the cultivation medium, as well as to assess the effect of differ …

02.09.2026journal-article

Problems of Gathering Treatment and Transportation of Oil and Oil Products

SORPTION MATERIALS FOR PURIFICATION OF WATER BODIES FROM OIL PRODUCTS BASED ON SURFACE-MODIFIED TECHNOGENIC FOAM SILICATE

A.V. Perfilev, O.N. Tsybulskaya, T.V. Ksenik, E.T. Gasymov, A.A. Yudakov, S.B. Yarusova, Yu.I. Shashina, M.A. Karpenko, V.Yu. Mayorov, M.V. Pavlov

The paper presents the results of a study of the sorption characteristics of adsorbents obtained through thermochemical gas-phase hydrophobic modification of the surface of a man-made aluminosilicate raw material – porous foam silicate. The porous structure, the degree and nature of surface modification, and the mechanism of adsorption of emulsified petroleum products from aqueous media were investigated. The total porosity of the foam silicate samples ranged from 84.70 to 88.44%. It was found that after the modify …

02.09.2026journal-article

JMIR AI

A Clinical AI-Based System (MoodMon) for Affective Disorders: Algorithm Development and Validation

Marlena Sokół-Szawłowska, Łukasz Święcicki, Katarzyna Kolasa, Katarzyna Kaczmarek-Majer

Abstract Background Psychiatry needs objective technological tools to address global staffing shortages, stigma, and other systemic challenges. An AI-based system for mood monitoring (MoodMon) was developed along with a mobile app for smartphones to detect changes in the mental state of individuals with major depressive disorder (MDD) and bipolar disorder (BD) based on acoustic features derived from speech signals. A long-term, naturalistic study of the MoodMon system represents a breakthrough in biomarker validati …

02.09.2026journal-article

Translational Psychiatry

Treatment response prediction in major neurocognitive disorder with depression using the scalp-to-cortex distance of TMS targets: implications for personalized dose estimation

Hanna Lu, Sandra Sau Man Chan, Suk Ling Ma, Arthur Dun-Ping Mak, Lin Shi, Li Zhang, Linda Chiu Wa Lam

Abstract Neuronavigated repetitive transcranial magnetic stimulation (rTMS) has shown encouraging efficacy in treating various brain disorders. However, substantial inter-individual heterogeneity in treatment response remains a major challenge. In this secondary analysis of a randomized clinical trial, we examined the predictive performance of transcranial features in relation to output measures and responses to rTMS treatment. Fifty-five elderly patients with depression and cognitive impairments were randomly assi …

02.09.2026journal-article

Sosiaalilääketieteellinen Aikakauslehti

Äitiysneuvolassa työskentelevien ammattilaisten käsityksiä inkontinenssin ennaltaehkäisystä ja hoidosta

Tuulia Lahtinen, Marjaana Jones, Tiina Vaittinen, Pilvikki Absetz

The prevention and treatment of incontinence within maternity clinic services is significant from both individual and societal perspectives. Incontinence causes health and social disadvantages for individuals, but it also contributes to environmental burden and economic costs for society. These negative impacts can be reduced by investing in measures of early prevention and treatment. In this article, we examine how health care professionals working in maternity clinics describe the prevention and treatment of inco …

02.09.2026journal-article

European Journal of Clinical Microbiology & Infectious Diseases

Prognostic value of the identified genus of anaerobic bacteria in bloodstream infection beyond host-related risk factors: a five-year retrospective cohort study

Andrea Harmath, Ágnes Jakab, Zoltán Tóth, Aliz Bozó, Bence Balázs, László Majoros, Renátó Kovács

Abstract Background Anaerobic bacteraemia is an uncommon but clinically significant bloodstream infection associated with substantial mortality. The respective roles of pathogen-specific and host-related factors in determining outcomes are not fully elucidated. Aim To identify predictors of mortality in anaerobic bacteraemia and to evaluate whether genus-based microbiological classification offers prognostic value beyond established clinical risk factors. Methods A retrospective cohort study was performed involving …

02.09.2026journal-article

Cardiopulmonary Physical Therapy Journal

Safe Mobilization Practices of Patients on Impella 5.5® Ventricular Assist Devices: The Right Patient, the Right Timing, the Right Team

Katelyn Black, Stephanie Smith, Stephanie Koepke

Purpose: The Johnson & Johnson MedTech Impella 5.5 ® is a temporary mechanical circulatory support (tMCS) device that supports cardiac output in the setting of cardiogenic shock. Older Impella ® models provide less cardiac output and limit mobility because of femoral insertion sites. It is widely accepted that early mobility is important in the ICU setting, but there is a lack of mobility-specific guidelines for patient selection or procedural interventions with the Impella 5.5 ® . This study describes a framework …

02.09.2026journal-article

The American Journal of Tropical Medicine and Hygiene

Comparison of Oviposition and Adult Trapping to Monitor wMel Introgression for Wolbachia-Based Vector Control

Elisabeth Nelson, Thiago N. Pereira, Erica Milena de Castro Ribeiro, Bianca Daoud Mafra e Silva, Carolina Camillo, Thiago Rodrigues da Costa, Mauro M. Teixeira, Albert I. Ko, Derek A. T. Cummings, Luciano A. Moreira

ABSTRACT. Wolbachia introgression into Aedes aegypti ( Ae. aegypti ) mosquito populations is an effective strategy for preventing dengue and is currently under evaluation for WHO prequalification. The standard protocol for trials and deployments currently being conducted in Brazil by the World Mosquito Program (WMP) for long-term monitoring of Wolbachia introgression involves the use of BG-Sentinel traps (BG-traps; Biogents AG [Regensburg, Germany]), which are labor-intensive and costly. More affordable alternative …

02.09.2026journal-article

Annals of African Medicine

Quantitative Apparent Diffusion Coefficient (ADC) Mapping as a Preoperative Biomarker for Tumor Grade and Myometrial Invasion in Endometrial Carcinoma

Kamlesh Kumar Ratre, Manish Kumar, Priya Singh, Priti Kumari

Abstract Background: The decision to perform systematic lymphadenectomy in endometrial carcinoma (EC) depends heavily on preoperative staging. We investigated the utility of diffusion-weighted imaging (DWI) and quantitative apparent diffusion coefficient (ADC) mapping to noninvasively predict the presence of EC and its histological tumor grade. Materials and Methods: This prospective case–control study included 30 women with histopathologically confirmed EC (cases) and 30 women with normal endometrium (controls). P …