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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
31.08.2026journal-article

Journal of NeuroEngineering and Rehabilitation

Cortical neuromodulation by vibration-induced illusion of movement is observed in older individuals, but not in individuals with acute stroke: a cross-sectional fNIRS study

Brieuc Léger, Pascal Auzou, Élodie Fourdrinoy, Mathilde Sarrazin, Sylvine Celot, Céline Gay, Barbara de Dieuleveult, Clara Cohen, Canan Özsancak, Stéphane Perrey

Abstract Background Together with the aging of the world population, stroke incidence is expected to increase in the coming years. Stroke is frequently associated with sensorimotor impairments of the upper limb, including proprioceptive deficits, that substantially impair motor control and quality of life. Understanding how physiological aging and acute stroke affect proprioceptive processing is therefore crucial for developing targeted rehabilitation strategies. Methods Vibration-induced illusion of movement was a …

31.08.2026journal-article

The Journal of Clinical Endocrinology & Metabolism

Continuous glucose monitoring to track metabolic changes in youths with cystic fibrosis before and after initiation of elexacaftor/tezacaftor/ivacaftor therapy

Alfonso Galderisi, Hadija Marchiori, Laurence Weiss, Alix Besançon, Nathalie Stremler, Aline Lustre, Djouher Sahki, Anne-Sophie Bonnel, Isabelle Sermet-Gaudelus, the MODUL-CF group, Marianne Alison, Baptiste Arnouat, Melissande Baravalle, Mahassen Barboura, Jeanne Barillon, Audrey Barzic, Lilia Benhalla, Myriam Benhamida, Khadidja Bennour, Laureline Berteloot, Katia Bessaci, Antoine Bessou, Marie Biard, Thiphaine Bihouée, Aurore Blonde, Nesrine Bouleghlem, Bertrand Bruneau, Stéphanie Bui, Aline Carsin-Vu, Mathilde Casson-Masselin, Justine Chanclud, Frédérique Chedevergne, Camille Cisterne, Harriet Corvol, Laure Cosson, Laure Couderc, Carole Couette, Marie-Laure Dalphin, Paola de Carli, Eric Deneuville

Abstract Introduction Glucose tolerance abnormalities can be detected in preschool and school-age children with cystic fibrosis. There is limited data on the impact of CFTR modulator elexacaftor/tezacaftor/ivacaftor (ETI) on their trajectories. We examined CGM metrics before and after ETI initiation across different pediatric age groups. Methods We included participants from the French MODUL-CF real world study aged 2-18 years with at least 24 hours of CGM data before initiation of ETI and a 2nd CGM 12±3 months fol …

31.08.2026journal-article

Annals of Rehabilitation Medicine

Immediate Effects of Walking Training With Elastic Ankle Support Devices on Walking and Mobility of Ambulatory Individuals With Stroke

Thaksin Chanata, Sugalya Amatachaya, Teerawat Nithiatthawanon, Jirabhorn Wannapakhe, Wannapai Chanwised, Arpassanan Wiyanad, Thiwabhorn Thaweewanakij, Wilairat Namwong

Objective: To compare the immediate effects of walking training without or with an ankle support device (ASD) on spatiotemporal gait parameters, mobility, and satisfaction among 20 ambulatory participants with chronic stroke.Methods: This crossover design required the participants to complete the four 30-minute walking training conditions in a randomized order: without ASD, with ankle-foot orthosis (AFO), with long ankle sling made from 3- to 4-inch elastic bandage, and with elastic ankle support equipment (EASE) d …

31.08.2026journal-article

World Journal of Advanced Research and Reviews

PREDICTORS OF THERAPEUTIC RESPONSE IN PATIENTS WITH SHOULDER PAIN AT THE DEPARTMENT OF PHYSICAL MEDICINE AND MEDICAL REHABILITATION, AIRLANGGA UNIVERSITY HOSPITAL, 2024

Natasya Salsabilla Zulkarnain Putri, Nanda Aulya Ramadhan, Muhammad Nazmuddin

Shoulder pain is a musculoskeletal disorder that can lead to functional limitations and reduced quality of life. This study aimed to identify predictors of therapeutic response in patients with shoulder pain treated at the Department of Physical Medicine and Medical Rehabilitation, Airlangga University Hospital. This retrospective analytical observational study used medical records of patients treated from January to December 2024. Of the 260 medical records reviewed, 219 met the inclusion criteria. Data collected …

31.08.2026journal-article

International Journal of Pharmaceutical and Bio Medical Science

Synergistic Effects of Pursed-Lip Breathing and Music Therapy on Oxygen Saturation in Pulmonary Tuberculosis: A Narrative Literature Review

Carlos Borromeu de Assis Belo, Indah Sri Wahyuningsih, Dwi Heppy Rochmawati, Erna Melastuti

Background: Pulmonary tuberculosis remains a significant global health problem and is often associated with impaired gas exchange leading to decreased oxygen saturation. Non-pharmacological interventions such as pursed-lip breathing and music therapy have been explored to improve respiratory function and enhance patient comfort. Objective: This review aims to analyze the synergistic effects of pursed-lip breathing and music therapy on oxygen saturation in patients with pulmonary tuberculosis. Methods: A narrative l …

31.08.2026journal-article

Molecules

Phospholipid–Prednisolone Conjugates for Targeted IBD Therapy: Structural Design, Synthetic Approaches, Optimization, and Computational Evaluation

Sapir Ifrah, Adi Jabarin, Ludmila Yarmolinsky, Keren Cohen-Hagai, Mordechai Deutsch, Arik Dahan, Shimon Ben-Shabat

Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, is a chronic disorder characterized by persistent intestinal inflammation. Although corticosteroids such as prednisolone effectively control disease symptoms, prolonged treatment is associated with severe side effects, including immune suppression and metabolic disturbances. To enable site-specific drug delivery, four phospholipid–linker–prednisolone conjugates were designed and synthesized as prodrugs targeting the overexpression o …

31.08.2026journal-article

Journal of Marital and Family Therapy

Are You Qualified, ChatGPT? Examining Clinical Skills and Competencies of ChatGPT in Delivering Systemic Interventions

Gizem Erdem, Nilüfer Kafescioğlu, Gökçenay Başer

ABSTRACT Large language model agents such as ChatGPT are increasingly used for relationship advice and mental health support, with many users describing these interactions as therapeutic. This study assessed the clinical and cultural competence of a GPT‐based model trained to provide systemic interventions aligned with the AAMFT Code of Ethics and core skills. A volunteer client discussed a relational concern with the model, and the resulting transcript was evaluated by 12 experienced supervisors using standardized …

31.08.2026journal-article

Archives of Physiotherapy

Concurrent validity of a novel digital dynamometer for assessing performance on the Cranio-Cervical Flexion Test

Marco Barbero, Daniele Lonati, Marco Griseri, Corrado Cescon, Alessandro Bonafine, Tiziano Negrisolo, Emanuele Falzone, Samuel Pedrucci, Erik Cattrysse, Deborah Falla

Introduction: The Cranio-Cervical Flexion Test (CCFT) is a validated clinical test used to evaluate deep cervical flexor muscle function. A pressure biofeedback unit (PBU) has traditionally been the reference device. Recently, a new portable digital device known as the Neuromuscular Cranio-cervical Device (NOD) has been developed as a potential alternative.Methods: In this cross-sectional concurrent validation study, 88 participants were recruited from four outpatient physiotherapy practices, including individuals …

31.08.2026journal-article

Jounral of Educational Therapist

A Consensual Qualitative Study on the Components of a Psychodynamic Counselor Training Group Program for Novice Counselors

THE KOREAN SOCIETY OF EDUCATIONAL THERAPY, Moon-Kyoung Bae, Sung-Moon Cheon

This study explored directions for a psychodynamically based counselor training group program for novice counselors. Semi-structured interviews with 11 experts averaging 28 years of clinical experience and over 20 years of teaching and supervision were analyzed using Consensual Qualitative Research (CQR), yielding 9 domains and 44 categories. First, experts viewed the therapist's character and self-awareness as the foundation of psychodynamic counseling, and saw novices' core difficulty as a lack of awareness of th …

31.08.2026journal-article

İstanbul Esenyurt Üniversitesi Sağlık Bilimleri Dergisi

Artificial Intelligence in Physiotherapy and the Limits of Clinical Reasoning: A Narrative Review

Nilgün Çırak

Objective: This narrative review examines current applications of artificial intelligence (AI) in physiotherapy and rehabilitation and evaluates the limits of AI-supported clinical reasoning, with emphasis on therapeutic touch, human interaction, ethical and medico-legal responsibility, professional autonomy, and human oversight.Materials and Methods: Literature on AI in physiotherapy and rehabilitation was reviewed using a narrative approach. Original studies, qualitative research, reviews, and conceptual publicat …

31.08.2026journal-article

Frontiers in Oncology

Precision-guided therapy in dialysis-dependent classic hairy cell leukemia: a case report

Sindhusha Veeraballi, Madhu Bhargavi Chandra, Eric J. Vick

Background Classic hairy cell leukemia (HCL) is a rare, indolent B-cell lymphoproliferative disorder characterized by bone marrow fibrosis causing pancytopenia, splenomegaly, and a near-universal BRAF V600E mutation. Purine nucleoside analogs (PNAs) are the standard first-line therapy but are contraindicated in patients with significantly advanced chronic kidney disease (CKD) or end-stage renal disease (ESRD) due to renal excretion and risk of prolonged myelosuppression. Data on the use of targeted therapies, such …

31.08.2026journal-article

Frontiers in Artificial Intelligence

Utilising speech-derived biomarkers to detect Alzheimer's disease with BERT-based language models: a machine learning study

Zara Khanna, Dean Ho, Alexandria Remus, Marlena Raczkowska, Railey Montalan, Pramit Saha

Background Early diagnosis is critical for effective management of Alzheimer's disease (AD). While prior studies have shown that speech features can be indicative of AD, most existing work consolidates multiple biomarkers, making it difficult to isolate the contribution of individual features. Objective This study systematically isolates individual speech biomarkers to quantify their distinct contributions to AD classification performance of language models (LMs) and determine whether targeted biomarker selection i …

31.08.2026journal-article

Journal of Applied Rehabilitation Counseling

Navigating First Jobs: A Conceptual Framework for Advancing Self-Determination in High School Employment for Transition Students

Rommel Johnson, Stephanie Picazo

Paid employment during high school is among the strongest predictors of postschool competitive integrated employment for students with disabilities. Yet, access to early work experiences and the quality of those experiences remain uneven. The existing transition research emphasizes the importance of obtaining paid work; however, there is less guidance on how to structure first jobs to promote self-determined behavior that supports long-term career development. This conceptual article advances self-determination the …

31.08.2026journal-article

International Journal of Molecular Sciences

Natural and Synthetic Compounds, Swords for Glioblastoma Therapy: From Tumor to Its Microenvironment

Bingxia Huang, Yan Wang

Glioblastoma (GBM) is the most aggressive primary brain malignancy in adults, which remains difficult to treat because of extensive intratumoral heterogeneity, intrinsic and acquired treatment resistance, a profoundly immunosuppressive tumor microenvironment (TME), and restricted drug delivery across the blood–brain barrier (BBB). Owing to their relatively low molecular mass, potential for BBB penetration, and ability to modulate multiple targets, natural and synthetic compounds have attracted increasing interest a …

31.08.2026journal-article

Current Cardiology Reviews

Effect of Impedance-Guided Fluid Therapy on Treatment Outcomes of Patients with Heart Failure: A Systematic Review and Meta-Analysis

Yichi Liu, Yuting Xie, Shuangshuang Du, Jingming Zheng, Yutong Qiu, Weixi Liu, Jiayi Liu, Min Mao

Introduction: Traditional volumetric assessment methods have limitations in the management of HF. The clinical value of impedance-guided monitoring (including bioelectrical impedance analysis [BIA], lung/thoracic impedance [LI], or intrathoracic impedance monitoring [IIM]) for quantifying extracellular fluid status remains controversial. This study aims to systematically evaluate the effect of impedance-guided fluid management on rehospitalization rates, mortality, and other outcomes in patients with HF. Methods: P …

31.08.2026journal-article

Annals of Rehabilitation Medicine

Dual-Task Exercises for Dynamic Balance, Motor Function, Functional Mobility, and Dual-Tasking in Individuals With Parkinson’s Disease: A Meta-Analysis With Meta-Regression

Stanley J Winser, Mohammad Jobair Khan, Abu Jor, Priya Kannan

To evaluate the (1) effectiveness of dual-task (DT) exercise in improving dynamic balance, motor function, functional mobility, dual-tasking, and falls, and (2) influence of DT intervention parameters on treatment effects in individuals with Parkinson’s disease (PD). A comprehensive literature search was conducted across 12 electronic databases to identify relevant published articles from inception to September 2025. Risk of bias, methodological rigour, and evidence quality were evaluated using the RoB-2, PEDro, an …

31.08.2026journal-article

Frontiers in Allergy

Persistent presumed allergic fungal rhinosinusitis during tezepelumab therapy with improvement after revision surgery: a case report

Bashayer Saad Hamoud Alsultan, Aasem Gharamah Alshehri, Leen Abdulmohsin Sarhan, Ghadah Saad H. Alsultan, Yahya Shabi

Allergic fungal rhinosinusitis (AFRS) is a clinically distinct subset of type 2 chronic rhinosinusitis with nasal polyps (CRSwNP), characterized by markedly elevated total IgE, fungal sensitization, and expansile disease with bony remodeling. Definitive diagnosis requires all five Bent and Kuhn criteria, including histopathological demonstration of eosinophilic mucin without tissue invasion and a positive fungal stain. Tezepelumab, a monoclonal antibody against thymic stromal lymphopoietin (anti-TSLP), has phase 3 …

31.08.2026journal-article

Journal of Scientific Research and Reports

Enhancing Psychological Well-being in Elderly Care Homes through Horticultural Therapy

P. Steffi, G. S. Sreedaya, G. K. Beela, V. Biji, V. S. Chinchu, J. R. Shalini

Horticultural therapy is a non-pharmacological approach that may support psychological well-being among older adults living in care homes. This study assessed changes in psychological well-being following a structured geriatric horticultural therapy intervention among residents of a government-run care home in Thiruvananthapuram, Kerala, India. Of 127 residents eligible for the baseline survey, 60 participants with the highest baseline scores were purposively selected. The intervention was delivered three times per …

31.08.2026journal-article

Frontiers in Rehabilitation Sciences

Habilitation and assistive devices for persons with disabilities: a new approach to respect for human rights and inclusion

Giampiero Griffo

In recent years, the development of assistive technologies has profoundly changed the idea of what it means to be human and what humans are capable of, in particular for persons with disabilities; the United Nations Convention on the Rights of Persons with Disabilities (UNCRPD) highlights that disability is a social construction. New concepts have been developed, such as empowerment, enabling, inclusion, habilitation, and human rights, that have changed the meaning of making tools available to encourage full partic …

31.08.2026journal-article

International Journal of Molecular Sciences

[225Ac]Ac-iPSMA Radiopharmaceuticals for Targeted Alpha Therapy: Design, Synthesis, and Preclinical Evaluation

Daniel García-Arce, Myrna Luna-Gutiérrez, Pedro Cruz-Nova, Abraham Vidal-Limon, Nallely Jiménez-Mancilla, Liliana Aranda-Lara, Erika Azorín-Vega, Enrique Morales-Avila, Paola Rodríguez-López, Clara Santos-Cuevas, Guillermina Ferro-Flores, Blanca Ocampo-García

Prostate-specific membrane antigen (PSMA) is a validated theranostic target with clinical relevance extending beyond prostate cancer to PSMA-expressing neovasculature in solid tumors. Despite the success of 177Lu-PSMA therapy, a significant proportion of patients experience disease recurrence or partial responses, motivating the development of targeted alpha therapy (TAT) approaches. In this study, novel monomeric and dimeric 225Ac-labeled PSMA inhibitors, [225Ac]Ac-DOTA-iPSMA ([225Ac]Ac-D-iPSMA) and [225Ac]Ac-MACR …

31.08.2026journal-article

DA'WA: Jurnal Bimbingan Penyuluhan & Konseling Islam

Efektivitas Rational Emotive Therapy Berbasis Mindfulness Training terhadap Overthinking Siswa MTs

Rofi'ud Darojatin Nisaa, Dewi Kadek Yati Fitria, Kharisma Firdaus Tegar

Penelitian ini bertujuan untuk mengetahui efektivitas Rational Emotive Therapy berbasis Mindfulness Training dalam menurunkan tingkat overthinking pada siswa kelas VIIIB MTsT Mardhlatillah Singaraja Tahun Ajaran 2025/2026. Penelitian ini menggunakan pendekatan kuantitatif dengan desain Pre-Experimental, yaitu One-Group Pretest-Posttest Design. Sampel penelitian berjumlah 8 siswa yang dipilih menggunakan teknik purposive sampling berdasarkan hasil pretest dengan tingkat overthinking kategori sangat tinggi. Data diku …

31.08.2026journal-article

Revista Ibero-Americana de Humanidades, Ciências e Educação

MUSICOTERAPIA COMO INTERVENÇÃO COMPLEMENTAR NO CONTROLE SINTOMÁTICO DA DOENÇA DE ALZHEIMER

Felipe Teles Bahia, Jaqueline Santos Teles Bahia

A Doença de Alzheimer (DA) é uma afecção neurodegenerativa progressiva e a principal causa de demência em idosos, caracterizada pela deterioração cognitiva, perda de memória e alterações severas de comportamento e humor. Diante do aumento da expectativa de vida e das limitações do tratamento farmacológico convencional em reverter a morte neuronal, intervenções alternativas e não invasivas têm sido amplamente buscadas. O presente estudo objetiva analisar a eficácia da musicoterapia como instrumento terapêutico compl …

31.08.2026journal-article

Oriental Journal Of Chemistry

Occupational Exposure to Airborne Fiberglass Fibers Generated during Orthopedic Cast Removal: Exposure Assessment, SEM–EDX Characterization and Respiratory Health among Healthcare Workers

Zulkifli Abu Bakar, Irman Abdul Rahman, Anuar Ithnin, Siti Nurazwanni Wahishad, Normah Awang

Orthopedic cast removal with oscillating saws may release airborne fiberglass fibers and dust into healthcare workers' breathing zones. This multicentre comparative cross-sectional study characterized airborne fiberglass fiber exposure during routine cast removal. It examined respiratory health among healthcare workers in five public hospitals in the Klang Valley, Malaysia. Personal and area air samples were collected and analyzed by phase-contrast microscopy in accordance with NIOSH NMAM 7400. Selected filter samp …

31.08.2026journal-article

Acute and Critical Care

A nationwide 1-day point-prevalence study on rehabilitation practices for intensive care unit patients in South Korea

Jiyeon Kang, Myung-Jun Shin, Suk-Kyung Hong, Min-Hyung Rhee, Jinhee Jung, Jiwon Hong

Background: Early rehabilitation is important in critical care, but nationwide data on rehabilitation practices in Korean intensive care units (ICUs) are lacking. This study reports the findings of a 1-day point-prevalence survey to assess current ICU rehabilitation practices and associated ICU characteristics.Methods: A nationwide, 1-day point-prevalence survey was conducted on December 18, 2024, across 116 ICUs with a 24-hour follow-up. Data were collected at the ICU level and included ICU characteristics, staffi …