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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
31.08.2026journal-article

Hospital Pharmacy

Extensive Subcutaneous Hematoma in a Patient Receiving Nigella sativa Oil, Dual Antiplatelet Therapy, and Oxaliplatin-Based Chemotherapy: A Case Report

Amirhosein Arab, Sima Ramezaninejad, Ebrahim Salehifar

Background: Nigella sativa (black seed) oil is a commonly used herbal supplement. Here, we report the case of a patient enrolled in a clinical trial of N. sativa oil for chemotherapy-induced peripheral neuropathy (CIPN), who developed a large subcutaneous hematoma while receiving oxaliplatin-based chemotherapy in combination with dual antiplatelet therapy. Case Presentation: A 51-year-old man with colon cancer receiving FOLFOX plus cetuximab and dual antiplatelet therapy developed a large subcutaneous hematoma whil …

31.08.2026journal-article

Current Drug Therapy

Immunoinformatic Prediction of B-Cell and MHC-Associated Epitopes from Echinococcus granulosus Adenylate Kinase 1 (ADK1) as a Candidate Vaccine Antigen

Saman Hashemi, Hanieh Shams Khakriz, Yagoob Garedaghi, Mohammad Jalali Niroumand, Shadan Ghiabi, Ezatollah Ghasemi, Sasan Khazaei, Hamidreza Majidiani, Farhad Hajializadeh

Introduction: The present study focused on Echinococcus granulosus adenylate kinase 1 (ADK1) to characterize its main biochemical features and predict potential B- and T-cell epitopes that may support its evaluation as a candidate for multi-epitope vaccine development. Methods: Multiple online servers were used for in silico analysis of the EgADK1 protein. Results: The analysis predicted ADK1 as a cytoplasmic protein of about 22 kDa, with appropriate hydrophilicity (GRAVY: –0.286), stability (instability index: 17. …

31.08.2026journal-article

Physiotherapy Canada

A Theory-Based Approach to Adapting a Task-Oriented Community Exercise Programme for Virtual Delivery for People With Balance and Mobility Limitations

Elizabeth L. Inness, Anessa Koussiouris, Navaldeep Kaur, Margot Catizzone, Diane Tse, Gayatri Aravind, Jennifer O’Neil, Lisa Sheehy, Joyce Fung, C. Allyson Jones, Heidi Sveistrup, Nancy M. Salbach

Abstract Purpose: Despite the health benefits for people with mobility limitations of participating in community-based exercise programmes (CBEPs), accessing and implementing in-person CBEPs can be challenging. We describe a theory-based approach to adapting a group task-oriented, in-person CBEP targeting balance and mobility to a virtual format. Method: We used the Knowledge-to-Action and Medical Research Council frameworks to guide adaptation of an established CBEP for virtual delivery. We undertook consultations …

31.08.2026journal-article

Jounral of Educational Therapist

Comparing the Effects of Experiential Intervention Using the Empty-Chair Technique and Cognitive Reappraisal in the Context of Parent-Adolescent Conflict

THE KOREAN SOCIETY OF EDUCATIONAL THERAPY, Hwa-sil Lee

This experimental study examined the effects of an experiential therapeutic intervention using the empty-chair technique. Negative emotions were activated by having participants recall conflict experiences with their adolescent children. Reductions in negative affect and willingness to experience were compared among an experiential therapeutic intervention group, a cognitive therapeutic intervention group, and a control group. Eighty-one middle-aged parents in the Seoul metropolitan area with an adolescent children …

31.08.2026journal-article

JPGI (Jurnal Penelitian Guru Indonesia)

Effectiveness of mindfulness – based acceptance and commitment therapy counseling on the self-acceptance of children in conflict with the law: a single-subject experimental study

Nurul Aya Mufidah Rahmat Rahmat, Sahril Buchori, M. Amirllah, Syahril Syahril

Children in Conflict with the Law (CICL) are prone to low self-acceptance due to stigma, guilt, and emotional pressure during legal proceedings. Given that CICL often experience cognitive fusion with negative self-labels and engage in avoidant coping, Acceptance and Commitment Therapy (ACT) was selected for its emphasis on psychological flexibility through mindfulness, acceptance, cognitive defusion, and values-based committed action. This study aims to analyze changes in Subject N's self-acceptance through mindful …

31.08.2026journal-article

Karaelmas İş Sağlığı ve Güvenliği Dergisi

Occupational Health and Safety Perceptions of Healthcare Workers in Traditional and Complementary Medicine Practice Centers: A Cross-Sectional Study in Istanbul

Fatma Polat, Aybüke Günaltay, Ali Timucin Atayoglu

This cross-sectional study investigated the knowledge, awareness, and consciousness levels regarding Occupational Health and Safety (OHS) among healthcare professionals in Traditional and Complementary Medicine (T&CM) Centers in Istanbul. A total of 52 participants from eight centers were surveyed between August 2024 and January 2025 using validated tools. The response rate was 86.7%. The participants showed high consciousness (92.0%), moderate awareness (80.0%), and lower knowledge (77.0%). The allied health profe …

31.08.2026journal-article

Pakistan Armed Forces Medical Journal

Knowledge-Based Attitudes of Medical Undergraduates at King Edward Medical University in Antibiotic therapy and Antibiotic Resistance

Alishba Rasool, Areej Sardar Malik, Muhammad Awais, Sikander H. Rasool, Ayesha Rasool, Saira Afzal

Objective: To assess knowledge gaps among medical undergraduates regarding antibiotic use and resistance. Study Design: Cross-sectional study. Place and Duration of Study: King Edward Medical University, Lahore Pakistan, from Jul to Aug 2024. Methodology: Data were collected using a pre-designed, pre-tested questionnaire from 300 medical students divided into two groups: Group-A (Years 1–3) and Group-B (Years 4–5). Results: Of the 300 participants, 42% were male and 57% female. Group A comprised 25% of students, wh …

31.08.2026journal-article

Jurnal Ilmiah Psikologi Terapan

Neurolinguistic stimulation, emotion regulation, and neurofeedback for childhood speech delay: A longitudinal case-based study

Firmawati Ummah, Desi Purnama Sari, Istiarsyah Istiarsyah, Shin Yeen Shiw, Attahirah, Sauva Yarda

Children with speech delay often face co-occurring challenges in language, emotional regulation, and attention. This exploratory single-subject longitudinal study examined preliminary neurophysiological and behavioral correlates of a multicomponent intervention integrating neurolinguistic stimulation, emotion-regulation training, neurofeedback, and caregiver-mediated strategies in a five-year-old boy with significant speech delay. Data were collected at three time points using Mental Load (ML) indices, Brain Functi …

31.08.2026journal-article

Oriental Journal Of Chemistry

Design and Validation of a Reverse Phase HPLC Method for Simultaneous Determination of Doxycycline and Metronidazole in Targeted Periodontal Therapy

Anuj Kumar, Phool Chandra, Anurag Verma, Vishal Trivedi, Amit Sharma, Himanshu Sharma, Arvind Raghav, Neetu Sachan

The reverse-phase high-performance liquid chromatography (RP-HPLC) method has been shown to exhibit excellent repeatability, accuracy, and reproducibility when used to simultaneously assess doxycycline and metronidazole for the management of localised periodontal diseases.Low levels of interference were achieved through optimisation and high-resolution separation. Validation was accomplished according to recommendations from the International Conference on Harmonisation (ICH) and included assessments for linearity, …

31.08.2026journal-article

Technology and Disability

Factors associated with user experience of speech rehabilitation applications with hearing impairment in Shanghai: Implications for future continuance research

Huajun Zhang, Xiong Zhang

Background Speech rehabilitation applications can support communication and rehabilitation activities outside clinical settings. However, providing advanced functions alone may not ensure a positive user experience. Users may also consider the effort required to operate an application, its usefulness and value, whether it offers an improved approach to rehabilitation, and how reliably it performs. Objective This study examined factors associated with the user experience of speech rehabilitation applications among a …

31.08.2026journal-article

Frontiers in Sustainable Cities

Health risk assessment of benzene, toluene, ethylbenzene, and xylene among occupational and residential populations at landfill, Indonesia

Intan Nur'azizah Rahman, Katharina Oginawati, Benno Rahardyan, Muhayatun Santoso, Dikdik Sidik Purnama, Nurul Fahimah, Muhammad Amin

Personal monitoring of benzene, toluene, ethylbenzene and xylene (BTEX) exposure at municipal solid waste landfills remains scarce in Indonesia, despite its importance for capturing individual exposure variability and improving health risk assessment. This study evaluated inhalation health risks associated with personal BTEX exposure among occupational and residential populations living around an open dumping landfill. Personal air samples were collected from 56 participants, including scavengers, landfill workers, …

31.08.2026journal-article

Frontiers in Oncology

Feasibility and acceptability of ice plant intensive cream in preventing hand-foot syndrome in breast cancer patients undergoing Doxorubicin and/or Docetaxel therapy: a randomized controlled pilot study

Marcela Winkler, Renée Arnhold, Dennis Anheyer, Christel Idler, Felicitas Löffler, Georg Sauer, Claudia Löffler, Holger Cramer

Introduction Hand-Foot Syndrome (HFS) is a common side effect in patients undergoing chemotherapy, particularly with Doxorubicin and Docetaxel and can substantially impair quality of life. This study aimed to assess the feasibility and acceptability of using Ice Plant Intensive Cream ( Mesembryanthemum crystallinum ) to prevent HFS in breast cancer patients, within a predefined recruitment target of 36 participants. Methods In this randomized controlled pilot study, patients with breast cancer scheduled to receive …

31.08.2026journal-article

Journal of NeuroEngineering and Rehabilitation

Cortical neuromodulation by vibration-induced illusion of movement is observed in older individuals, but not in individuals with acute stroke: a cross-sectional fNIRS study

Brieuc Léger, Pascal Auzou, Élodie Fourdrinoy, Mathilde Sarrazin, Sylvine Celot, Céline Gay, Barbara de Dieuleveult, Clara Cohen, Canan Özsancak, Stéphane Perrey

Abstract Background Together with the aging of the world population, stroke incidence is expected to increase in the coming years. Stroke is frequently associated with sensorimotor impairments of the upper limb, including proprioceptive deficits, that substantially impair motor control and quality of life. Understanding how physiological aging and acute stroke affect proprioceptive processing is therefore crucial for developing targeted rehabilitation strategies. Methods Vibration-induced illusion of movement was a …

31.08.2026journal-article

The Journal of Clinical Endocrinology & Metabolism

Continuous glucose monitoring to track metabolic changes in youths with cystic fibrosis before and after initiation of elexacaftor/tezacaftor/ivacaftor therapy

Alfonso Galderisi, Hadija Marchiori, Laurence Weiss, Alix Besançon, Nathalie Stremler, Aline Lustre, Djouher Sahki, Anne-Sophie Bonnel, Isabelle Sermet-Gaudelus, the MODUL-CF group, Marianne Alison, Baptiste Arnouat, Melissande Baravalle, Mahassen Barboura, Jeanne Barillon, Audrey Barzic, Lilia Benhalla, Myriam Benhamida, Khadidja Bennour, Laureline Berteloot, Katia Bessaci, Antoine Bessou, Marie Biard, Thiphaine Bihouée, Aurore Blonde, Nesrine Bouleghlem, Bertrand Bruneau, Stéphanie Bui, Aline Carsin-Vu, Mathilde Casson-Masselin, Justine Chanclud, Frédérique Chedevergne, Camille Cisterne, Harriet Corvol, Laure Cosson, Laure Couderc, Carole Couette, Marie-Laure Dalphin, Paola de Carli, Eric Deneuville

Abstract Introduction Glucose tolerance abnormalities can be detected in preschool and school-age children with cystic fibrosis. There is limited data on the impact of CFTR modulator elexacaftor/tezacaftor/ivacaftor (ETI) on their trajectories. We examined CGM metrics before and after ETI initiation across different pediatric age groups. Methods We included participants from the French MODUL-CF real world study aged 2-18 years with at least 24 hours of CGM data before initiation of ETI and a 2nd CGM 12±3 months fol …

31.08.2026journal-article

İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi

Comparison of the Effectiveness of Schroth Exercise Method and Combined (Manual Therapy + Schroth Exercise Method) Method in Idiopathic Adolescent Scoliosis

Seyyedeh Sahra Karimi, Ömer Şenel

Aim: This study aimed to assess the impact of the Schroth exercise method alone versus a combination of the Schroth exercise method and manual therapy on adolescent idiopathic scoliosis patients.Method: Participants aged 11-18 were divided into two groups: one practicing Schroth exercises and the other combining these exercises with manual therapy. Gibbosity, static and dynamic balance, visual perception, and quality of life were measured at baseline and after 3-month intervention period.Results: Results indicated …

31.08.2026journal-article

Cancers

Longitudinal Improvements in Treatment Delivery Efficiency for MR-Guided Radiation Therapy: An 8-Year Single-Institution Experience

Robert A. Herrera, Sirikorn Unsri, Kathryn E. Mittauer, Rupesh Kotecha, Adeel Kaiser, Matthew D. Hall, Yongsook C. Lee, Yonatan Weiss, Tatiana Bejarano, Eyub Y. Akdemir, Mattison J. Flakus, Nikolai Strusberg-Fernandez, Ranjini Tolakanahalli, Nema Bassiri, Maria Ayala, Noah S. Kalman, Diane Alvarez, Tino Romaguera, Minesh P. Mehta, Alonso N. Gutierrez, Michael D. Chuong

Purpose: While magnetic resonance-guided radiation therapy (MRgRT) may provide significant clinical advantages, delivery times tend to be longer than other radiation therapy (RT) modalities and published data on these times are limited. We evaluated longitudinal treatment times across our 8-year institutional MRgRT experience. Methods/Materials: A retrospective analysis of patients treated at our institution on a 0.35-Tesla MR-Linac between April 2018 and April 2026 was performed. All fractions were delivered with …

31.08.2026journal-article

Frontiers in Pharmacology

Safety and efficacy of honeysuckle therapy for epidermal growth factor receptor inhibitor-related rash: a systematic review and meta-analysis

Li-Feng Liu, Shuang Liu, Jie Jiao, Fang-Yuan Zhang

Background Epidermal growth factor receptor inhibitors (EGFRIs) -related rash is prevalent, and honeysuckle therapy (HT) has been extensively utilized for skin rash. However, high-quality clinical evidence supporting the use of HT for EGFRIs-related rash remains scarce. This study aims to systematically assess the prophylactic and therapeutic effectiveness and safety of HT in managing EGFRIs-related rash. Methods A systematic literature search was performed in six electronic databases from their inception to 25 Mar …

31.08.2026journal-article

Applied Sciences

Arthrogenic Muscle Inhibition After Anterior Cruciate Ligament Injury and Reconstruction: Neurophysiological Mechanism, Assessment and Rehabilitation

Natale Criseo, Biagio Zampogna, Tamir Dib, Oriana Pugliesi, Alessandro Carrozzo, Gabriele Di Carlo, Lorenza Siracusano, Danilo Leonetti

Background: Persistent quadriceps weakness is a common consequence of joint injury, particularly following anterior cruciate ligament (ACL) injury and reconstruction. While traditionally attributed to muscle atrophy and disuse, growing evidence suggests that neural mechanisms play a central role. Arthrogenic Muscle Inhibition (AMI) is a neurally mediated impairment in the ability to voluntarily activate periarticular musculature following joint injury, occurring within a broader neurophysiological response involvin …

31.08.2026journal-article

Thyroid®

TSH-Lowering Levothyroxine Therapy Is Associated with Higher rT3 and Stable fT3 Levels in Euthyroid Patients with Papillary Thyroid Microcarcinoma During Active Surveillance

Yoshiki Furumura, Akira Miyauchi, Mitsuru Ito, Mitsushige Nishikawa, Nozomi Yamasaki, Hideyuki Iwayama, Masumi Iwasa, Masashi Yamamoto, Makoto Fujishima, Yasuhiro Ito, Takashi Akamizu

Background: We previously reported that lowering serum thyrotropin (TSH) levels with levothyroxine (LT4) during active surveillance (AS) of papillary thyroid microcarcinoma (PTMC) was associated with a trend toward a lower rate of disease progression. In euthyroid patients with PTMC managed with mild TSH-lowering therapy, free thyroxine (fT4) levels increased, whereas free triiodothyronine (fT3) levels remained unchanged overall, thereby raising questions regarding thyroid hormone metabolism. We therefore investiga …

31.08.2026journal-article

Annals of Rehabilitation Medicine

Immediate Effects of Walking Training With Elastic Ankle Support Devices on Walking and Mobility of Ambulatory Individuals With Stroke

Thaksin Chanata, Sugalya Amatachaya, Teerawat Nithiatthawanon, Jirabhorn Wannapakhe, Wannapai Chanwised, Arpassanan Wiyanad, Thiwabhorn Thaweewanakij, Wilairat Namwong

Objective: To compare the immediate effects of walking training without or with an ankle support device (ASD) on spatiotemporal gait parameters, mobility, and satisfaction among 20 ambulatory participants with chronic stroke.Methods: This crossover design required the participants to complete the four 30-minute walking training conditions in a randomized order: without ASD, with ankle-foot orthosis (AFO), with long ankle sling made from 3- to 4-inch elastic bandage, and with elastic ankle support equipment (EASE) d …

31.08.2026journal-article

World Journal of Advanced Research and Reviews

PREDICTORS OF THERAPEUTIC RESPONSE IN PATIENTS WITH SHOULDER PAIN AT THE DEPARTMENT OF PHYSICAL MEDICINE AND MEDICAL REHABILITATION, AIRLANGGA UNIVERSITY HOSPITAL, 2024

Natasya Salsabilla Zulkarnain Putri, Nanda Aulya Ramadhan, Muhammad Nazmuddin

Shoulder pain is a musculoskeletal disorder that can lead to functional limitations and reduced quality of life. This study aimed to identify predictors of therapeutic response in patients with shoulder pain treated at the Department of Physical Medicine and Medical Rehabilitation, Airlangga University Hospital. This retrospective analytical observational study used medical records of patients treated from January to December 2024. Of the 260 medical records reviewed, 219 met the inclusion criteria. Data collected …

31.08.2026journal-article

International Journal of Pharmaceutical and Bio Medical Science

Synergistic Effects of Pursed-Lip Breathing and Music Therapy on Oxygen Saturation in Pulmonary Tuberculosis: A Narrative Literature Review

Carlos Borromeu de Assis Belo, Indah Sri Wahyuningsih, Dwi Heppy Rochmawati, Erna Melastuti

Background: Pulmonary tuberculosis remains a significant global health problem and is often associated with impaired gas exchange leading to decreased oxygen saturation. Non-pharmacological interventions such as pursed-lip breathing and music therapy have been explored to improve respiratory function and enhance patient comfort. Objective: This review aims to analyze the synergistic effects of pursed-lip breathing and music therapy on oxygen saturation in patients with pulmonary tuberculosis. Methods: A narrative l …

31.08.2026journal-article

Molecules

Phospholipid–Prednisolone Conjugates for Targeted IBD Therapy: Structural Design, Synthetic Approaches, Optimization, and Computational Evaluation

Sapir Ifrah, Adi Jabarin, Ludmila Yarmolinsky, Keren Cohen-Hagai, Mordechai Deutsch, Arik Dahan, Shimon Ben-Shabat

Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, is a chronic disorder characterized by persistent intestinal inflammation. Although corticosteroids such as prednisolone effectively control disease symptoms, prolonged treatment is associated with severe side effects, including immune suppression and metabolic disturbances. To enable site-specific drug delivery, four phospholipid–linker–prednisolone conjugates were designed and synthesized as prodrugs targeting the overexpression o …