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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
31.08.2026journal-article

Polymers

Mechanical and Surface Behavior of Contemporary Restorative Materials Exposed to Topical Hemostatic Agents After Artificial Aging: An In Vitro Study

İlhan Kaya, Sena Nur Yıldırım, Akif Demirel

Hemostatic agents are frequently used during pediatric dental procedures and may inadvertently contact restorative materials. This study evaluated the fracture-load and surface roughness of contemporary pediatric restorative materials following exposure to different surgical hemostatic agents after artificial aging. A total of 360 disc-shaped specimens were prepared from three pediatric restorative materials (composite, compomer, and glass hybrid), with separate sets of 180 specimens allocated to fracture-load and …

31.08.2026journal-article

Service & Tourism: Current Challenges

IMMERSIVE TOURS AS A FACTOR IN ENHANCING THE APPEAL OF REGIONAL TOURISM FOR YOUNG PEOPLE (THE CASE OF THE RYAZAN AND YAROSLAVL REGIONS)

Lyudmila A GRITSAI

As the tourism industry undergoes transformation under the influence of the experience economy and digitalization, the search for new formats of guided tours capable of sustaining young people’s interest in regional tourism has become particularly relevant; this is especially significant for regions with rich but underutilized cultural and historical potential. This article examines the problem of the insufficient appeal of traditional excursions for young people and argues for the possibility of addressing this is …

31.08.2026journal-article

Revista de Pesquisa Cuidado é Fundamental Online

Strategies for relieving chronic low back pain in elderly people / Estratégias para alívio da lombalgia crônica em pessoas idosas

Cícera Patrícia Daniel Montenegro, Ana Claudia Oliveira de Araújo, Bruna Luísa Melo de Aquino Lemos Corrêa, Maria Eleidiane Soares Mamede Coutinho, Sérgio Augusto Silva Paredes Moreira, Beatriz Aparecida Ozello Gutierrez

Objetivo: identificar as principais estratégias para alívio da lombalgia crônica em idosos. Método: trata-se de uma pesquisa de campo com abordagem mista, amostra composta por 20 idosos da zona rural de Guarabira/PB e 20 da zona urbana de João Pessoa/PB. Realizou-se uma entrevista semiestruturada cujos dados transcritos foram processados pelo software IRaMuTeQ. Resultados: emergiram quatro classes semânticas: Acesso dos idosos à tecnologia; Inclusão digital no cotidiano dos idosos; Atividades predisponentes à lomba …

31.08.2026journal-article

Sensors

Spectral and Directed Connectivity EEG Markers for Classifying Alzheimer’s Disease, Frontotemporal Dementia, and Healthy Controls with Exploratory Photobiomodulation Case-Study Projection

Zoran Šverko, Saša Vlahinić, Miroslav Vrankić, Nino Stojković

Alzheimer’s disease (AD) and frontotemporal dementia (FTD) are neurodegenerative disorders with partially overlapping clinical manifestations, making early and differential diagnosis challenging. This study investigated whether electroencephalography (EEG)-derived spectral features and Granger-causality (GC)-based directed functional connectivity features can characterize and classify AD, FTD, and healthy control (HC) subjects. Resting-state eyes-closed EEG recordings from 88 participants were analyzed, including 3 …

31.08.2026journal-article

Nature Aging

Multimorbidity patterns influence mobility disability prevention in frail older adults from the SPRINTT trial

Davide Liborio Vetrano, Caterina Gregorio, Federico Triolo, Luca Soraci, Antonio Cherubini, Matteo Tosato, Stephan von Haehling, Emanuele Marzetti, Francesco Landi, Riccardo Calvani

Abstract Preserving independence in older adults is a public health priority. Lifestyle interventions can prevent physical disability, but whether their efficacy is influenced by multimorbidity profiles is unclear. In this post hoc analysis of the SPRINTT randomized trial ( NCT02582138 ), we investigated whether the efficacy of a multicomponent intervention (physical activity with technological support and nutritional counseling) differed across multimorbidity patterns. We included 1,199 community-dwelling adults a …

30.08.2026journal-article

DEC Journal : Art and Design

To Empower People Who are in Disadvantage Groups and Build Community Through a Handmade Jewelry-Making Workshop From Reclaimed Materials

Chanida Kanmuang

The author believes that every material in the world possesses its own beauty and uniqueness, and that human beings, as creators, can enhance the value of those materials through design. Even discarded materials retain intrinsic value. In the current global context, beverage consumption and the resulting waste generation remain at high levels. Global soft drink consumption exceeds 500 billion liters annually, making beverage packaging a significant component of municipal solid waste. Although only a portion is pack …

30.08.2026journal-article

Alzheimer's & Dementia

Perinatal lead (Pb) exposure and alterations to amyloid beta and metabolic profiles in the brain

Rachel K. Morgan, Evelyn K. Matei, Junru Pan, Tomoko Ishikawa, Katelyn M. Polemi, Ingrid Bergin, Sean P. Ferris, Hao Wang, Dana C. Dolinoy, Kelly M. Bakulski, Justin A. Colacino

Abstract INTRODUCTION Developmental neurotoxicant exposures (e.g., lead [Pb]) are suspected contributors to dementia. Dementia is characterized by amyloid beta (Aβ) plaques and dysregulated metabolism. To better understand the relationship between environment and dementia risk, we assessed the impact of perinatal Pb exposure on dementia‐related outcomes in the murine brain. METHODS Female mice were exposed to 32 ppm Pb or control water during gestation and lactation. Offspring were aged out to 3 weeks or 18 months. …

30.08.2026journal-article

Logopedija

Uloga geste u leksičkom prizivu osoba s afazijom

Karolina Lice

Jedan od najčešćih simptoma afazije su teškoće u leksičkom prizivu, zbog čega se u rehabilitaciji sve više istražuju strategije i metode koje mogu olakšati dosjećanje riječi i poboljšati komunikaciju. Jedna od njih je uporaba geste kao dijela multimodalne komunikacije. Cilj ovog preglednog rada je identificirati postojeće gestovne terapijske pristupe i metode u rehabilitaciji afazije, utvrditi pospješuju li gestovne terapije oporavak leksičkog priziva kod osoba s afazijom i jesu li učinkovitije od jezičnih terapija …

30.08.2026journal-article

Alzheimer's & Dementia

Longitudinal plasma phosphorylated tau217 classification and the association with Alzheimer's disease progression

Guoyu Lan, Wang Liao, Mingxing Jiang, Jiayi Zhu, Wenqing Ran, Fernando Gonzalez‐Ortiz, Xiang Fan, Hongjie Yang, Dai Shi, Laihong Zhang, Anqi Li, Yue Cai, Pan Sun, Zhengbo He, Xin Zhou, Jie Yang, Yalin Zhu, Mingxu Li, Wenjing Huang, Binhui Liu, Yiying Wang, Xinyue Ma, Rong Ma, Yimei Zhang, Chao Huang, Zhen Liu, Qingyong Wang, Liemin Zhou, Fang Xie, Ying Han, Zhen Liang, Xuhui Chen, Mengjie Dong, Guanxun Cheng, Lu Wang, Benyan Luo, Yan‐jiang Wang, Xiaochun Chen, for the Alzheimer's Disease Neuroimaging Initiative, Jiawei Xin

Abstract INTRODUCTION Longitudinal diagnostic and prognostic validity of plasma phosphorylated tau217 (p‐tau217) in Alzheimer's disease (AD) remains uncertain. METHODS In this multi‐cohort study of 2117 individuals, we established baseline plasma p‐tau217 thresholds for amyloid‐β–positron emission tomography (Aβ‐PET) and assessed their longitudinal classification stability and prognostic relevance for AD‐related outcomes. RESULTS Baseline‐defined cutoffs achieved high and sustained accuracy (86%–95%) for Aβ‐PET pos …

30.08.2026journal-article

Journal of Prevention and Health Promotion

Pastor-Led Technology-Delivered Mental Health Promotion Program for Improving Quality of Life Among Older Black Adults in the United States

Carolyn M. Tucker, Kirsten G. Klein, Kaylyn A. Garcia, Eloise M. Harrison, Kelly L. Folsom, Guillermo M. Wippold

Older Black adults experience high rates of adverse health concerns that contribute to high morbidity and premature mortality. To address these health disparities, it is recommended that health promotion interventions are culturally tailored (e.g., leveraging faith and spirituality) to the unique needs of older Black adults. Such interventions must recognize that older Black adults often report experiencing barriers to engagement in interventions such as transportation and cost. The purpose of the present study was …

30.08.2026journal-article

Reflections: A Journal of Community-Engaged Writing and Rhetoric

Age-Friendly Homepages

Rachel Tofteland-Trampe

Becoming an AARP-designated “age-friendly'' state is a five-year project, and states who choose to do so, often create a website devoted to policy efforts and initiative updates. On these websites, visual rhetoric and writing play a central role in communicating with the public. These websites have implications for how aging is represented and who is included in this online space, both in photographs and in a website’s alternative text (alt text). To conduct my analysis, I selected three “age-friendly” state homepa …

30.08.2026journal-article

Indian Journal of Public Administration

Process Reforms for a People-centred City: Ease of Living in Dibrugarh, Assam

Sudarshan Ozah, Partha Pratim Borah

This article examines issues of the ease of living emanating from the current urban scenario of Dibrugarh in Assam. Based on primary data collected through fieldwork, this study contextualises local lived experiences within the national framework. This research argues that Dibrugarh city’s urbanisation has outpaced institutional capacity and development due to administrative advancement, economic growth and population migration, generating drastic insufficiency of infrastructural development, social sustainability, …

30.08.2026journal-article

International Journal For Multidisciplinary Research

A Study on Prescribing Pattern of Medications and Adherence in Geriatric Patients Having Type 2 Diabetes Mellitus with Hypertension.

Mohankumar L, Ashika M P, Sandip Paul, Rupesh Senapati

Type 2 diabetes mellitus (T2DM) and hypertension (HTN) are common co-morbidities in older adults and, together with age-related polypharmacy, impair rational prescribing and medication-taking behavior. OBJECTIVES: To analyze the pattern of prescribing oral antidiabetic and antihypertensive drugs in geriatric patients having type 2 diabetes mellitus (T2DM) and hypertension (HTN), to evaluate the medication adherence by Morisky medication adherence scale-8 (MMAS-8), and to determine barriers affecting adherence. Meth …

30.08.2026journal-article

Journal of Korean Society of Dental Hygiene

Factors influencing the sustained intention to participate in oral care for older adults among caregivers and dental hygienists in long-term care facilities: based on the COM-B model

Su-Jung Cho, Su-Young Lee

Objective: This study examined the factors underlying the sustained intention to participate in oral care for older adults among caregivers and dental hygienists in long-term care facilities, using the capability, opportunity, motivation, and behavior (COM-B) model. Methods: A survey was conducted with 205 participants experienced in providing oral care for older adults in long-term care facilities in the Seoul metropolitan area. Data were analyzed using descriptive statistics, independent t-tests, Pearson’s correl …

30.08.2026journal-article

Alzheimer's & Dementia

Extracellular matrix remodeling upregulates hippocampal neurogenic niche stiffness and impairs neurogenesis in Alzheimer's disease

Weiqi Sun, Biyu Yang, Hanyuan Zheng, Qi Wang, Yajiao Shi, Gandig Wang, Wang Yin, Hui Wang, Xuetao Qi, Yun Yao, Jiaxin Wang, Shuang Cui, Kun Cui, Jian Mao, Yiyuan Xia, Jianwen Deng, Siyuan Zhao, Zhihao Wang, Fengyu Liu, Ming Yi, Jiuyang Ding, Weidong Le, Xinyan Li, Junliang Yuan, You Wan, Jie Zheng

Abstract INTRODUCTION Preserving adult hippocampal neurogenesis alleviates cognitive deficits in Alzheimer's disease (AD), yet how biophysical alterations in such as stiffness in the neurogenic niche regulate neurogenesis remains unclear. METHODS Stiffness in the hippocampal dentate gyrus subgranular cell zone (SGZ) of 5×FAD mice was measured using atomic force microscopy. Extracellular matrix (ECM) components in mice and AD patients were profiled through proteomics. Hydrogels were supplemented in the SGZ to upregu …

30.08.2026journal-article

Current Alzheimer Research

Decoding Frontotemporal Dementia: Genes, Proteins and Prospects for Precision Medicine

Kaushik Raj, Nandani Kumari, Pragya Bharti, Ranjeet Kumar, Dharmendra Kumar

Frontotemporal Dementia is an umbrella term for several neurodegenerative disorders that have a similar presentation pattern, which is accompanied by neural damage and brain tissue loss in the frontal and temporal regions. Recent studies have observed that the heterogeneity of Frontotemporal Dementia (FTD) is reflected in clinical features, genetics, and molecular perspectives. Specifically, the major forms of pathology in FTD are linked to abnormal protein accumulation, which includes tau, TAR DNA-binding protein …

30.08.2026journal-article

Anemon Muş Alparslan Üniversitesi Sosyal Bilimler Dergisi

Determinants of Life Satisfaction and Happiness Levels of Older Individuals in Türkiye Using Binary and Ordered Choice Models

Muhammet Kutlu

This study aims to examine the factors influencing life satisfaction and happiness among individuals aged 65 and over in Türkiye, two main indicators of subjective well-being. For this purpose, using the Turkish Statistical Institute (TURKSTAT) 2023 Türkiye Older Persons Profile Survey micro dataset, binary logit and binary probit models were estimated to explain the life satisfaction variable, and ordered, stereotype, and generalized ordered logit models were estimated to explain the happiness level variable. The …

30.08.2026journal-article

Polymer Engineering & Science

The Effect of the Aging Process of Polyamide 11 Used in Flexible Pipelines and Its Influence on the Permeability of Carbon Dioxide

Antônio Pedro Andrade da Cunha Ponciano Gomes, Frederico Gonçalves de Albuquerque Dias, Sijmon Van der Wal, Marysilvia Ferreira da Costa

ABSTRACT This study investigates how long‐term natural aging affects the CO 2 permeability of polyamide 11 (PA11) pressure sheaths recovered from decommissioned flexible risers. PA11 samples were extracted from two 18‐year‐old risers—a gas‐lift line and an oil‐production line—and characterized by differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), dynamic mechanical analysis (DMA), and corrected inherent viscosity (CIV) to assess crystallinity, plasticizer content, thermal stability, and mole …

30.08.2026journal-article

Journal of Engineering Education

Beyond parents and educators: Older siblings as influential figures in nonformal engineering contexts

Amber Simpson, Sawsan Werfelli, Kelli Paul

Abstract Background Given the growing need for a well‐prepared engineering workforce, strategic investments must extend beyond formal education to include nonformal learning environments. While prior research highlights the role of parents, educators, and mentors in shaping young children's engineering development, siblings remain an understudied yet influential force. Purpose This study examined older siblings' roles when interacting with their younger siblings on engineering design tasks within two nonformal lear …

30.08.2026journal-article

Frontiers on Healthcare Research

The Relationship Between the Jakarta Cardiovascular Score and Physical Activity: Screening of Cardiovascular Risk Factors in Older Adults

Department of Cardiology and Vascular Medicine, Dr. M. Djamil General Hospital, Padang, Indonesia, Citra Kiki Krevani Citra, Restu Restu Restu, Wahyudi Firmana Wahyudi, Rusdy Kamal Rusdy, Fikri Satria Fikri, Jolatuvel Bahana Jolatuvel, Najmi Ilal Hayati Najmi Ilal, Hajar Nurfa Jirin Hajar Nurfa

Background: Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality worldwide, including in Indonesia, where low physical activity is a major modifiable risk factor. The Jakarta Cardiovascular Score (JAKVAS) was developed as a local modification of the Framingham Risk Score to better represent Indonesian populations by including physical activity as a variable. However, the quantitative relationship between physical activity level and JAKVAS has not been well established. Methods: This cross …

30.08.2026journal-article

Journal of Korean Society of Dental Hygiene

Long-term effects of smartphone app-based oral-musclestrengthening training in older adults

Jung-Hee Kang, Yoon-Young Choi, Kyeong-Jin Lee, Hyun-Young Moon, Kyeong-Hee Lee

Objectives: To investigate the long-term effects of smartphone app-based oral-muscle-strengthening training in older adults. Methods: A randomized controlled trial using a pretest-posttest control group design was conducted. Older adults were randomly assigned to an experimental group or a control group. The experimental group participated in a 12-week oral-musclestrengthening program using smartphone app content from May to August 2025. Oral health, mental health, tongue strength, and pronunciation accuracy were e …

30.08.2026journal-article

Journal of Clinical Medicine

Renal Cell Carcinoma in the Geriatric Population: Toward a Frailty-Adapted Therapeutic Paradigm

Cemile Ozsurekci, Ufuk Yazar, Yusuf Acikgoz

Background: Renal Cell Carcinoma (RCC) primarily affects older adults, with incidence increasing with age. Older adults remain underrepresented in clinical trials, and treatment decisions are often extrapolated from younger populations. Age-related factors such as comorbidities, frailty, polypharmacy, and immunosenescence complicate management in the geriatric population. Methods: A narrative review of the literature was conducted, focusing on localized and metastatic RCC in older adults. The review comprehensively …

30.08.2026journal-article

Journal of Asian Medical Students' Association

Comparative Efficacy and Safety of Dual Orexin Receptor Antagonists (DORAs) Versus Z-Drugs for Insomnia in Older Adults : A Systematic Review

Given Anugraha Wijaya, Frederick Karel Himawan, Jason Conrad Tanely

Introduction Insomnia affects up to 48% of older adults globally, often treated with Z-drugs that increase the risk of cognitive impairment and falls.1,4 Dual Orexin Receptor Antagonists (DORAs) offer a targeted alternative by specifically suppressing wakefulness-promoting pathways to minimize these adverse effects.7,8 Method This systematic review of Randomized Controlled Trials was conducted using the PRISMA guideline with references found in multiple online databases including PubMed, ScienceDirect, Proquest and …

30.08.2026journal-article

European Journal of Preventive Cardiology

Fitness does not retire: cardiorespiratory fitness and risk of major adverse cardiovascular events in older adults

Sindre Midttun, Håvard Dalen, Einar Lund, Elisabeth K Vesterbekkmo, Inger-Lise A Aksetøy, Leonard Kaminsky, Jeff S Coombes, Ulrik Wisløff, Dorthe Stensvold

Abstract Aims To evaluate the association between cardiorespiratory fitness (CRF), directly measured as peak oxygen uptake (VO2peak), and the risk of major adverse cardiovascular events (MACE) in older Norwegian adults. Methods and results A total of 1547 individuals aged 70–77 years (784 women) from the Generation 100 Study, examined in 2012 and 2013, were studied. We defined MACE as the first occurrence of acute myocardial infarction, stroke, heart failure, or cardiovascular death. Sex- and cohort-specific VO2pea …