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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Student's Journal of Health Research Africa

<b>Influence of at-risk gambling on the mental well-being of the youth in Nakawa Division, Kampala District, Uganda. A cross-sectional study.</b>

Albert Louis Elwa, Clesistom Ahimbisibwe, Frank Kiyingi, Robert Oluka

Background: The football pools are still around today and are, in fact, the source of inspiration for fixed odds on gambling. To assess the influence of at-risk gambling on the mental well-being of the youth in Nakawa Division, Kampala District, Uganda. Methodology: The study employed a cross-sectional survey research design. Quantitative data were analysed using a computerised data analysis program known as the Statistical Package for Social Sciences (SPSS) version 25. Results: There was a significant but negative …

03.09.2026journal-article

Hospital Pediatrics

Prevalence and Characteristics of Mental Health Interventions Following Pediatric Hospitalization

Mariah L. DeSerisy, Julia A. Heneghan, Matt Hall, Daniel H. Choi, Leslie A. Dervan, Daniel Garros, Denise M. Goodman, Jason M. Kane, Joseph G. Kohne, Colin M. Rogerson, Nadia Roumeliotis, Vanessa Toomey, Adam C. Dziorny

BACKGROUND AND OBJECTIVES As survival after pediatric critical illness improves, attention has shifted to post–intensive care syndrome and the long-term mental health of pediatric intensive care unit (PICU) survivors, who have high rates of posttraumatic stress, anxiety, and depression. The objective of this study is to examine the rates of new mental health follow-up and psychopharmacology use among publicly insured children following PICU hospitalization, compared with those hospitalized on acute care wards. METH …

03.09.2026journal-article

Frontiers in Nutrition

The relationship between parental feeding practices and children’s health-related quality of life

Charlotte Juton, Silvia Torres, Gina Valdés-Querol, Luis Rajmil, Montserrat Fito, Santiago F. Gómez, Helmut Schröder

Background Healthy eating is essential throughout childhood and adolescence, and has been associated with better health-related quality of life (HRQoL). Healthy eating results from complex interactions, including the transmission of eating habits within families. Although parental feeding practices may influence children’s HRQoL through several plausible behavioral pathways, empirical evidence examining this association remains limited. Therefore, the objective of this study was to investigate the association betwe …

03.09.2026journal-article

Frontiers in Medicine

Case Report: Secondary syphilis with pulmonary involvement mimicking eosinophilic granulomatosis with polyangiitis — targeted next-generation sequencing as an adjunct in resolving an atypical non-exanthematous presentation

Shunjun Tang, Tiehan Zhang, Aiyi Hao, Bin Su, Bin Liu

Background The global resurgence of syphilis poses growing challenges for clinical diagnosis, particularly when atypical presentations without classic mucocutaneous lesions mimic systemic autoimmune diseases. Pulmonary involvement in secondary syphilis is rare and frequently misdiagnosed, leading to inappropriate immunosuppressive therapy. Case presentation A 24-year-old male presented with one month of inflammatory back pain and two weeks of cough, purulent sputum, and intermittent low-grade fever. He initially de …

03.09.2026journal-article

Frontiers in Medicine

Development and validation of a nomogram prediction model for perioperative delirium in older patients with osteoporotic fractures based on LASSO regression and multiple parameters

Ni Hua, Hongmei Yuan, Yanhong Wei, Zhenqi Wei, Yanping Feng, Yong Liu, Tongguang Xu, Suliang Zhao, Li Zhang, Xiaohong He

Background Perioperative delirium (POD) is a severe postoperative complication in older patients with osteoporotic fractures. This study aimed to establish a nomogram prediction model incorporating multisystem stress, inflammation and frailty-related biomarkers for risk prediction. Methods This retrospective cohort study included 176 older patients (≥65 years) with osteoporotic fractures. Potential predictors, including the rate-pressure product (RPP), systemic inflammation response index (SIRI) and prognostic nutr …

03.09.2026journal-article

F1000Research

Effect of Passive Versus Active Aquatic Therapy Over Conventional Physiotherapy in Patients With Chronic Low Back Pain: A Randomized Crossover Trial — Study Protocol

Ammar Mohamed, Watson Arulsingh, Praveen Kumar Kandakurti, Ramprasad Muthukrishnan

Background Chronic low back pain (CLBP) is a highly prevalent musculoskeletal disorder worldwide, often associated with long-term disability and reduced quality of life. 1,2 Conventional physiotherapy continues to be the cornerstone of management; however, alternative approaches such as aquatic therapy have gained increasing attention in recent years due to their surging therapeutic benefits. 3,4 Within aquatic rehabilitation, various methods including passive aquatic therapy (Watsu) and active aquatic therapy are …

03.09.2026journal-article

Ege Tıp Dergisi

Evaluating GPT-4.1 Mini and GPT-5 in Postmastectomy Lymphedema Patient Education: A Comparative Study of Usefulness and Reliability

Benil Nesli Ata, Ece Cinar, Sibel Eyigör

Aim: To compare the reliability and usefulness of GPT-4.1 mini and GPT-5 in postmastectomy lymphedema patient education.Materials and Methods: Twenty patient-centered questions were developed from reputable sources. Responses from both models were independently rated by three blinded physiatrists using 7-point Likert scales for reliability and usefulness.Results: GPT-5 demonstrated higher usefulness and reliability scores compared to GPT-4.1 mini (p = 0.005 and p = 0.021, respectively).Conclusions: Both models prod …

03.09.2026journal-article

Frontiers in Immunology

Overall survival with immune checkpoint inhibitors across treatment settings and clinical and PD-L1-defined subgroups in advanced esophageal squamous cell carcinoma: a systematic review and meta-analysis of randomized trials

Bing Wang, Xiaoyu Han, Zengli Shen

Introduction To quantify overall-survival effects of immune-checkpoint-inhibitor (ICI)-containing regimens by treatment line and to evaluate whether clinical characteristics or PD-L1 definitions modify relative treatment benefit in advanced esophageal squamous cell carcinoma (ESCC). Methods PubMed, Embase, the Cochrane Central Register of Controlled Trials, and Web of Science were searched from inception through 1 August 2026. Two reviewers independently screened records, assessed full texts, extracted data, and ev …

03.09.2026journal-article

Frontiers in Public Health

E-health literacy status and its influencing factors among college students majoring in sports

Yue Yin, Jing Chen, Wenqing Zhao, Linwang Hu, Hang Cai, Liang Gao

Objective To understand the level of e-health literacy among sports majors and its influencing factors, providing reference for developing measures to improve e-health literacy in this population. Methods An online survey was conducted among college students from 6 universities in Jiangsu Province using an e-health literacy questionnaire. SPSS 26.0 statistical software was used for χ 2 test. t -test, one-way ANOVA, and multiple linear regression analysis were employed to explore the influencing factors of e-health …

03.09.2026journal-article

Frontiers in Medicine

Necroptosis–senescence crosstalk in tubulointerstitial fibrosis: the mtDNA–cGAS–STING–PFKFB3 axis as a metabolic bridge

Donghui Wang, Hongxiang Zheng, Xinyue Zhang, Chenghua Zhang, Dandan Zhao, Shuqi Min, Shenju Wang

Background Chronic kidney disease progresses irreversibly toward tubulointerstitial fibrosis. Although renin-angiotensin system inhibitors and sodium-glucose cotransporter 2 inhibitors slow progression, they cannot block or reverse fibrosis. Recent work shows that necroptosis and cellular senescence in tubular epithelial cells are not independent events; they form a dynamically evolving continuum through the mitochondrial DNA-cyclic GMP-AMP synthase-stimulator of interferon genes-interferon regulatory factor 3-6-ph …

03.09.2026journal-article

Frontiers in Cellular and Infection Microbiology

Absolute quantification by mouthwash testing screens severe periodontitis and tracks species-specific microbial response to periodontal therapy

Je-Hyun Eom, Mu-Yeol Cho, Ji-Won Kim, Yunwoo Kim, Jeehyun No, Jiyoung Hwang, Seokwon Kim, Dahye Lee, Hanseung Baek, Bae-Kyung Kim, Young-Youn Kim, Soo-Bok Her, Dong-Yub Ko, Inseong Hwang, Hye-Sung Kim

Background Non-invasive molecular tools that can both screen for severe periodontitis and quantify treatment-associated pathogen changes remain an unmet need. We evaluated a non-invasive multiplex quantitative polymerase chain reaction (qPCR) mouthwash panel providing absolute colony-forming-unit (CFU) quantification of five periodontal pathogens ( Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, Prevotella intermedia, Fusobacterium nucleatum ), and asked whether a single test can both screen fo …

03.09.2026journal-article

Frontiers in Psychiatry

Anxiety- and depression-related somatic symptoms and atlantoaxial disorders: potential mechanistic links and clinical implications

Shuxian Yang, Qianru Li, Wanying Shi, Xiaoyun Liu

Background Anxiety and depressive disorders often include pain, dizziness, headache, fatigue, nausea, and sleep disturbance. These symptoms may also occur in atlantoaxial disorders, but overlap does not establish a shared cause. Objective To examine whether clinical or mechanistic evidence supports an association between objectively defined atlantoaxial disorders and somatic symptom burden in people with anxiety or depression, while distinguishing direct evidence from inferences based on general neck-pain research. …

03.09.2026journal-article

Frontiers in Public Health

Mental disorders in the Black population: a scoping review

Rondinelli Salvador Silva, Yasmim Souza Rodrigues, Eduardo Sodré de Souza, Bruno Pereira da Silva, Luanda Ferreira Dias de Souza, Igor Hagedorn Reis, Ana Paula de Morais e Oliveira, Deivison Faustino Mendes, Patricia Lima Ferreira Santa Rosa

Introduction Mental disorders, psychiatric diagnosis, DSM/ICD classification, and mental health care represent major sources of global morbidity shaped by biological processes, social stressors, structural racism, inequities, and access barriers. In the Black population, racism, discrimination, social exclusion, and institutional bias may affect recognition, diagnosis, treatment, prognosis, and psychiatric outcomes. This scoping review aimed to map and summarize the available evidence on mental disorders in the Bla …

03.09.2026journal-article

Revista Psicologia, Diversidade e Saúde

Vínculos psicossociais e saúde mental de adolescentes: contribuições do psicodrama em interface com o existencialismo no contexto escolar

Gilmar Antoniassi Junior, Díone Gomes Silva

INTRODUCTION: Adolescence is a period of intense biopsychosocial transformations, in which emotional and social challenges may impact mental health, and school represents a strategic space for the promotion of well-being. OBJECTIVE: To analyze the mental health condition of adolescents, highlighting the influence of psychosocial bonds on their reasons for living, and to discuss the contributions of psychodrama in interface with existentialism in the school context. METHODS: This is a descriptive and exploratory stu …

03.09.2026journal-article

Criminal Behaviour and Mental Health

Assault‐on‐Law‐Enforcement: The Complications of Charges for Individuals on Mental Health Court Dockets

Steven Keener, Audrey Morrison

ABSTRACT Background Mental health courts divert individuals with serious mental illness away from imprisonment into community‐based treatment and supervision. Early research indicates that such treatment contracts can reduce recidivism and provide various other benefits. Aspects of eligibility for this diversion option are still under‐researched. Aims To explore the nature of alleged offences against people accepted into mental health courts (on mental health court dockets), and their demographic and mental health …

03.09.2026journal-article

Global Spine Journal

Testosterone Replacement Therapy is Associated With Increased Risk of Pseudarthrosis After Single-Level Anterior Cervical Discectomy and Fusion: A Propensity Matched Analysis

William Han, Kyle Stump, Karim Gubara, Prabhat Gottipati, Stephan Aynaszyan, Theresa Pazionis

Objective To evaluate whether preoperative testosterone replacement therapy (TRT) use is associated with increased risks of pseudarthrosis and reoperation following single-level anterior cervical discectomy and fusion (ACDF). Methods The TriNetX Research Network was queried to identify adult males aged 18 to 89 years who underwent single-level ACDF. Patients were separated into a TRT exposure group within 1 year before initial ACDF procedure as well as comparator cohort without TRT exposure that was matched 1:1 usi …

03.09.2026journal-article

Herz

Predicting LDL-cholesterol reduction variability on statin–ezetimibe therapy: insights from “Jena auf Ziel”

Umidakhon Makhmudova, Dieter Lütjohann, Franz Haertel, Anja Kerksiek, Robert Römer, Pellumb Haxhikadrija, Aurel Maloku, Beasat Samadifar, Sylvia Otto, P. Christian Schulze, Oliver Weingärtner

Abstract Background and aims Low-density lipoprotein cholesterol (LDL-C) is a causal risk factor for atherosclerotic cardiovascular disease (ASCVD). ESC/EAS guidelines recommend reducing LDL-C < 1.4 mmol/L and > 50% from baseline in patients with myocardial infarction. “Jena auf Ziel” (JaZ) is a prospective cohort study in which early combination therapy with atorvastatin 80 mg and ezetimibe 10 mg was initiated on admission in patients with ST-elevation myocardial infarction (STEMI) to reduce LDL‑C levels early and …

03.09.2026journal-article

Journal of Pharmaceutical Research and Integrated Medical Sciences

Multimodal AI and Machine Learning for Predictive Risk Stratification, Early Detection, And Clinical Management of Pica: Integrating Etiological and Pathophysiological Biomarkers

Yash Srivastav, Stuti Verma, Kamini Prajapati, Sandeep Prakash, Rajeev Kumar, Anubha Dhuriya, Anup Kumar Sirbaiya, Shivani Singh

Pica is a clinically significant and often overlooked feeding and eating disorder in which individuals have a persistent urge to eat or chew non-nutritious or non-food items and is linked to nutritional, hematological, behavioral, and environmental issues. Human studies have regularly found links between pica and iron deficiency and anemia, as well as between changes in hematological parameters, decreased ferritin, and decreased zinc concentrations; toxic-element exposure may also be a part of certain behaviors (li …

03.09.2026journal-article

Healthcare

From Intelligent Operating Room to Smart ICU: Digital Continuity, AI-Supported Decision-Making and CRRT as a Model of Pharmacokinetic Personalization in Critical Care

Leonard Azamfirei, Mirela Cecilia Oiaga, Mihai Claudiu Pui

Critically ill patients frequently move between the intensive care unit (ICU) and the operating room while remaining dependent on ventilatory, hemodynamic, antimicrobial, sedative, analgesic, and renal support. Although extensive perioperative data are generated, clinically relevant information may remain fragmented across devices and electronic systems. This narrative review synthesizes the literature published primarily between 2016 and 2026 on perioperative digital continuity, structured ICU–operating room hando …

03.09.2026journal-article

Livers

Early Versus Late Biliary Leakage After Hepatic Resection: Incidence, Risk Profiles, and Clinical Impact of Diagnostic Timing

Giacomo Paolini, Luca Tirloni, Ilenia Bartolini, Matteo Risaliti, Nicola Nocchi, Alessio Morandi, Maria Novella Ringressi, Antonio Taddei, Gian Luca Grazi

Background/Objectives: Post-hepatectomy biliary leakage (BL) remains a major source of postoperative morbidity. While traditional risk models treat BL as a single clinical entity, its chronological presentation follows distinct patterns that raise the hypothesis of distinct underlying pathophysiological mechanisms. This study aimed to stratify post-hepatectomy biliary fistulas into early and late onset to identify unique independent risk factors and clarify their separate risk profiles. Methods: This retrospective …

03.09.2026journal-article

Journal of Biology and Nature

Effect of Spirulina (Spirulina platensis) Administered in Drinking Water on Growth Performance and Health of the Rabbit (Oryctolagus cuniculus) in the Post-weaning Period

Sangaré Sidiki, Ouattara Adidjatou, Silué Fatogoma Etienne, Kimsé Moussa, Konan André Brou, Alassane Méité

Background: Spirulina (Spirulina platensis) is a nutrient-rich microalga that has been investigated as a feed supplement for improving animal growth and health. However, evidence regarding the effects of low doses of spirulina administered specifically through drinking water to rabbits during the post-weaning period remains limited, particularly for growth performance and health-related outcomes. Aims: To evaluate the effect of three doses of spirulina (Spirulina platensis) administered in drinking water on growth …

03.09.2026journal-article

Sports Health: A Multidisciplinary Approach

Sport-Specific Virtual Reality Tasks Reveal Distinct Patterns of Biomechanical Adaptation Compared With the Drop Vertical Jump

Jennifer A. Hogg, Scott Bonnette, Christopher D. Riehm, Staci Thomas, Manish Anand, Christopher A. DiCesare, Kim D. Barber Foss, Jed A. Diekfuss, Katie Beasley, Andrew Schille, Dustin van der Haar, Dustin R. Grooms, Janet Simon, Sophia Ulman, Richard Danilkowicz, Gregory D. Myer, Michael A. Riley

Background: Neuromuscular training (NMT) improves biomechanical risk factors associated with anterior cruciate ligament (ACL) injury yet has failed to abate increasing ACL injury rates at scale. This study assessed sport-specific sensorimotor adaptations resulting from a NMT protocol with additive real-time sensorimotor augmented biofeedback (augmented NMT [aNMT] or sham aNMT) in a standardized drop vertical jump (DVJ) task and in ecologically valid sport-specific tasks performed in a simulated virtual reality (VR) …

03.09.2026journal-article

BMC Medicine

Diagnostic accuracy of attended versus unattended automated blood pressure measurements compared to ambulatory blood pressure monitoring conducted by community health workers in rural sub-Saharan Africa

Ruth K. Lucinde, Modou Jobe, Alexander D. Perkins, Juliet O. Awori, Boniface Karia, Lamin Jobarteh, Robinson Oyando, Catherine Kalu, Sampa Sanneh, Clement Mwagwabi, Elminah Saru, Aurelia Brazeal, Samson Kinyanjui, Robert N. Peck, David A. Leon, Andrew M. Prentice, Benjamin Tsofa, Anoop S.V. Shah, Pablo Perel, Anthony O. Etyang, on behalf of the IHCoR-Africa Collaborators

Abstract Background Community Health Workers (CHWs) are increasingly being involved in screening for hypertension in rural sub-Saharan Africa. However the diagnostic accuracy of CHW-led attended (CHW present during procedure) and unattended (CHW absent) automated blood pressure (BP) in home settings has not been compared. Methods We conducted a cross-sectional, population-based diagnostic accuracy study in two health and demographic surveillance systems in Kenya and The Gambia. A random age-stratified sample of ind …