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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

British Journal of Nursing

Changing a Future Nurse undergraduate nursing programme to include more mental health content: initial evaluation

Laurence Baldwin, Judith McLeod, Rachel Bage, Frances Nicol, Maya Dixon, Lyndsay Khan, Helen Alcock-Towse, Donna-Marie Gordon, Catherine Shiels

The 2018 Nursing and Midwifery Council's ‘Future Nurse’ standards introduced increased genericism to UK nursing education, prompting criticism from specialist fields concerned about diluted field-specific knowledge. This article reports on a curriculum innovation at one UK university that addressed local implementation challenges through targeted module development to include an increased number of field-specific modules alongside core content. Among others, two new modules were introduced, one on mental health for …

03.09.2026journal-article

Gastrointestinal Disorders

Public Awareness, Label Literacy, and Consumer Behavior Regarding Gluten-Free Products in Arar, Saudi Arabia: Implications for the Supportive Environment of Immune-Mediated Gastrointestinal Disorders

Anshoo Agarwal, Sadeem Fahad Alwulayi, Asayil Saleh Alanazi, Ghaliah Farraj Alanzi, Rawan Sawab Albanaqi, Danah Naif Salem Alanzi, Nada Faleh AlRuwaili, Ghala Sultan Ageel Al Enezi, Baraah Abu Alsel, Safya E. Esmaeel, Fathia Ahmed Mersal, Naglaa A. Bayomy, Manal S. Fawzy

Background/Objectives: Community-level knowledge, food-label literacy, and consumer perceptions may shape the environment in which medically indicated gluten-free diets are followed. This study assessed prior exposure to the term “gluten,” ingredient-label literacy, perceived gluten-free product (GFP) cost, and purchasing behavior and intentions among adults in Arar, Saudi Arabia. Methods: A bilingual Arabic–English online cross-sectional questionnaire was administered to adult residents of Arar using non-probabili …

03.09.2026journal-article

Indian Journal of Nuclear Medicine

18 F FDG PET/CT in a Rare Case of CIC::NUTM1 Sarcoma

Yamini Dharmashaktu, Sameer Rastogi, Adarsh Barwad, Ritwik Nitin Wakankar, Shamim A Shamim

Capicua transcriptional repressor ( CIC )-rearranged sarcomas are exceedingly rare and highly aggressive malignancies affecting young individuals predominantly, and CIC::NUTM1 is thought to be a molecular variant of CIC-rearranged sarcoma. It has a poor prognosis and a rapid progression. Here, we present a case of a 3-year-old male with CIC::NUTM1 sarcoma of the pelvis who presented with complaints of constipation associated with severe pain for which 18 F fluorodeoxyglucose positron emission tomography/computed to …

03.09.2026journal-article

Eastern Mediterranean Health Journal

Assessing the predictors of treatment-seeking and health care access barriers among transgender individuals in Pakistan

Athar Memon, Sameena Ourangzaib, Benjamin R. Bates, Shiraz Shaikh

Background: Transgender individuals in Pakistan face barriers to health care access, increasing the risk of serious disease transmission. Aim: To identify the predictors of treatment-seeking intention and health care access delays among transgender individuals in Karachi, Pakistan. Methods: Between December 2024 and April 2025 we interviewed 360 individuals, aged ≥18 years, who identified as transgender and had accessed health care within the past 12 months. We analysed the data using SPSS version 20 and conducted …

03.09.2026journal-article

World Journal of Traditional Chinese Medicine

Simultaneous Harvesting of PINK1, Parkin, and FUNDC1 Ligands from Herbal Medicines Using “Net Fishing” Strategy

Zhong-Yu Fu, Min Zhang, Fan Zhang, Cheng-Zhu Song, Yang-Yang Fu, Tao Wang, Xu-Dong He, Mei Zhang, Jie Yu, Xing-Xin Yang

Abstract Objective: Targeting mitophagy represents a promising therapeutic strategy for human diseases. This study aimed to develop an efficient approach to simultaneously identify natural ligands for PTEN-induced kinase 1 (PINK1), Parkin, and FUN14 domain containing 1 (FUNDC1) – core regulators of mitophagy – from complex herbal medicine (HM) extracts. Materials and Methods: We established a novel capture strategy where PINK1, Parkin, and FUNDC1 proteins were individually and physically adsorbed on the surface of …

03.09.2026journal-article

European Journal of Endocrinology

Adverse health outcomes across the life course in individuals with six rare bone diseases: a 10-year population-based cohort study

Pascal Gaechter, Christian Meier, Emanuel Christ, Fahim Ebrahimi, Alexander Kutz, Gabor Szinnai

Abstract Background Rare bone diseases comprise a heterogeneous group of complex and disabling conditions. Evidence on age-specific hospitalization patterns and in-hospital outcomes across multiple rare bone diseases is limited. Methods Population-based cohort study using national hospitalization data (01/2012–12/2021). Among 11,092,151 hospitalizations, 2,875 admissions of children and adults with rare bone diseases were identified via ICD-10 codes (X-linked hypophosphatemia, osteogenesis imperfecta, fibrous dyspl …

03.09.2026journal-article

International Journal of Molecular Sciences

Myeloid-Derived Suppressor Cells (MDSCs) in Cardiovascular Risk of Obesity-Associated Diabetes

Rocío Flores-Campos, Lourdes Hontecillas-Prieto, Daniel J. García-Domínguez, Antonio Fernández-Suárez, Iker Egusquiza-Lasuen, Antonio Pérez, Josep Ribalta, Juan Pedro-Botet, Víctor Sánchez-Margalet, on behalf of the Immunology Group of the Spanish Society of Laboratory Medicine (SEMEDLAB), the Cardiovascular Disease Group of the Spanish Diabetes Society (SED)

The dysregulation of immune homeostasis and the persistence of chronic, low-grade inflammation represent core pathophysiological drivers governing the onset and progression of metabolic and cardiovascular disorders. Myeloid-derived suppressor cells (MDSCs) comprise a highly heterogeneous population of immature myeloid cells that are rapidly mobilized from the bone marrow in response to biological stressors, such as sustained tissue injury and chronic inflammatory signaling. Historically evaluated within oncology an …

03.09.2026journal-article

Frontiers in Immunology

HIV associated immune aging among people living with HIV: implications for long-term antiretroviral therapy and potential HIV cure interventions in sub-Saharan Africa

Praiscillia Kia, Edward Kankaka, Patricia Kankundiye, Marcel Tongo, Rose Nabatanzi, Tokameh Mahmoudi, Damalie Nakanjako

Background Clinical and biological consequences of accelerated immune aging are substantial, with growing evidence of increased risk of non-communicable diseases (NCD) among people living with HIV (PLHIV). However, there is limited understanding of reliable biomarkers of immune aging, singly or in combination, that can be used for monitoring HIV treatment in large longitudinal cohorts in sub-Saharan Africa (SSA). This review describes candidate biomarkers of immune aging during HIV treatment and their potential cli …

03.09.2026journal-article

Frontiers in Medicine

AI-enabled language technologies for language-mediated learning and clinical communication in international undergraduate dental education: a scoping review

Wenjuan Qiang, Xiaohong Deng, Tiezhou Hou, Le Qiang

Background International undergraduate dental students often learn and communicate in a language other than their first language, affecting terminology acquisition, clinical reasoning, patient explanations, informed consent, clinical communication, and patient safety. AI-enabled language technologies—including generative artificial intelligence (GenAI), large language models (LLMs), and neural machine translation (NMT)—may support these tasks, but their use in this population has not been systematically mapped. Met …

03.09.2026journal-article

Frontiers in Medicine

Fulminant group A streptococcal necrotizing fasciitis presenting as severe calf pain after pharyngitis in an adolescent: a case report

Lisa Roncoroni, Jan Kühle, Lampros Kousoulas, Katharina Müller-Peltzer, Dawid L. Staudacher

Background Invasive Group A Streptococcus (GAS) infection can rapidly progress to life-threatening conditions, including necrotizing fasciitis (NF) and streptococcal toxic shock syndrome (STSS). While typically associated with cutaneous breaches or underlying comorbidities, hematogenous seeding following primary pharyngeal infection is a rare but documented phenomenon. Early diagnosis is often complicated by subtle skin changes and the rarity of the disease. Case A previously healthy 17-year-old female presented wi …

03.09.2026journal-article

Wilderness & Environmental Medicine

Effects of Metal Climbing Gear and Lightning Safety Position During Simulated Lightning

Mathias Maurer, Wolfgang Lederer, Benjamin Treichl, Markus Isser, Sandra Bauchinger, Stephan Pack

Introduction When trapped in a climbing route during a thunderstorm, it is generally recommended that climbers should maintain a maximum distance from rock formations and water accumulations. It is common practice for climbers to untie themselves from the rope and deposit metal equipment a few meters away. Methods In an experimental study, the formation of upward leaders from metal gear attached to a climbing harness and the number of lightning strikes to rope, metal gear, and subject were evaluated. A lightning im …

03.09.2026journal-article

BMC Microbiology

First identification and characterization of a plasmid co-harbouring poxtA and cfr in a clinical linezolid-resistant Staphylococcus aureus isolate

Kang Xu, Kaixin Zhou, Linlin Xu, Qing Chen, Lianyan Xie, Feifei Gu, Aikuang Ma, Shuzhen Xiao, Jingyong Sun, Dongan Zhu

Abstract Background Linezolid remains an important treatment option for serious infections caused by Gram-positive pathogens; however, acquired oxazolidinone resistance genes carried by mobile genetic elements are an increasing clinical concern. In Staphylococcus aureus , cfr and poxtA have previously been reported together in the chromosomal mosaic transposon Tn 6349 , whereas complete plasmid-borne structures co-harbouring these genes remain poorly defined. Methods Isolate D2958 was identified by matrix-assisted …

03.09.2026journal-article

Microbial Drug Resistance

Using an Online Registry of Carbapenemase-Producing Gram-Negative Organisms to Report the Clinical Profile, Outcomes, and Phenotypic and Genotypic Resistances in Two Tertiary Level Hospitals in the Philippines (ORiGiN Study)

Cybele Lara R. Abad, Adrian Ronald A. Espino, Veil Maria T. Castro, Andrei Dominique Montero, Mark B. Carascal, Shanaia Esthelle Joy Daguit, Eariel Francisco, Lawrence S. Macalalad, Kim L. Cochon, Danice Faith Alombro, Benjo P. Ato, Jayson Lumasag, Ralph Bryan B. Hernandez, Anna Flor G. Malundo, Christel V. Gutierrez, Justin Allister Ong, Heather Gutierrez, Karl Abalajon, Marc Agnew M. Cajucom

Background: This study describes the clinical profiles, phenotypic and genotypic resistance mechanisms, and outcomes of patients with carbapenem-resistant infections (CRIs) using a registry. Methods: Hospitalized adults with CRIs in two tertiary institutions were included in this prospective study from January 1, 2023, to December 31, 2025. Results: A total of 411 patients were included. Half were male (207/411, 50.4%), with median age 59 (range 19–98) years. Hypertension (251, 65.5%), diabetes mellitus (150, 39.2% …

03.09.2026journal-article

Current Issues in Sport Science (CISS)

Digital Solutions in Exercise Therapy for Diabetes & Obesity: Using Smart Technology to Get People Moving

Othmar Moser

Physical activity and structured exercise are essential components of the management of diabetes and obesity (Moser et al., 2020)(Davies et al., 2022). Nevertheless, many people do not achieve recommended activity levels, and the translation of exercise recommendations into everyday life remains challenging. Digital solutions may help to overcome this gap by providing personalised guidance, continuous feedback and scalable support beyond traditional clinical settings (Moser et al., 2025). This keynote will explore …

03.09.2026journal-article

Journal of Intensive Care Medicine

Incidence and Risk Factors for Invasive Mechanical Ventilation Dependency in Japan: A Nationwide Retrospective Cohort Study

Hiroyuki Ohbe, Monique Daniels, Daisuke Kudo, Hiroki Matsui, Stef Groenewoud, Werner Brouwer, Hideo Yasunaga

Objectives To describe the incidence and risk factors for becoming dependent on invasive mechanical ventilation (IMV) in Japan. Design Retrospective cohort study using a nationwide inpatient database from April 1, 2014, to March 31, 2020. Setting More than 1500 acute care hospitals participating in the Diagnosis Procedure Combination Study Group Database, covering approximately 50% of all hospitalizations in acute care hospitals in Japan. Patients Adults (≥18 years), in whom IMV was initiated during hospitalization …

03.09.2026journal-article

European Journal of General Dentistry

Conservative Esthetic Approach for Crown Fracture with Pulp Exposure in a Young Male Patient: A Case Report with Mini-review

Naif N. Abogazalah

Abstract Traumatic dental injuries may hurt the social and psychological well-being of a young patient. Maxillary anterior teeth are the most affected teeth. In permanent dentition, the most common trauma involves clinical crown fractures, with or without pulp exposure. This article describes a case report of a 12-year-old male patient who exhibited dental trauma, which resulted in a complicated crown fracture with pulp exposure of tooth #11 (maxillary right central incisor). A partial pulpotomy was performed to pr …

03.09.2026journal-article

Journal of Imaging Informatics in Medicine

A Clinically Grounded Review of Medical Image Classification: Quantitative Insights into CNNs, Vision Transformers, and Hybrid CNN-ViT Models

Hamza Hussaini, Shahana Bano, Eyad Elyan, Carlos Francisco Moreno-Garcia

Abstract Medical image classification has advanced substantially with convolutional neural networks (CNNs), Vision Transformers (ViTs), and hybrid CNN–ViT architectures, yet clinical translation remains limited by dataset dependency, inconsistent evaluation practices, and insufficient external validation. This review provides a clinically grounded comparative synthesis of these model families across diverse medical imaging modalities. A structured literature review was conducted across PubMed, IEEE Xplore, Scopus, …

03.09.2026journal-article

Transplantologiya. The Russian Journal of Transplantation

A rare complication in a patient undergoing continuous ambulatory peritoneal dialysis

A. G. Yankovoy, V. A. Stepanov

Introduction. Continuous ambulatory peritoneal dialysis (PD) is one of the methods of treating patients in the structure of renal replacement therapy (RRT). The most common complications directly related to the peritoneal catheter usually occur during the first weeks and range from catheter dysfunction to dialysis peritonitis. Delayed intestinal perforation with a peritoneal catheter upon termination of peritoneal dialysis (PD) is extremely rare. Objective. The article describes a rare clinical case and successful …

03.09.2026journal-article

Journal of Clinical Medicine

Structural Deficit-Guided Reconstruction of an Extended Lower Eyelid–Bicanthal Defect

Zheng-Cai Wang, Zi-Chun Gu, Ying Hu, Jia-Qin Cai, Hua Li

Background/Objectives: Extended lower eyelid defects involving both lamellae and canthal supports require restoration of lining, support, vascularized coverage, and horizontal stability. We describe a two-stage reconstruction guided by structural deficits and available autologous tissues. Methods: A 63-year-old man underwent staged excision with frozen-section margin control for conventional-type basal cell carcinoma involving almost the entire right lower eyelid. A lengthened septal chondromucosal graft restored p …

03.09.2026journal-article

Toxins

Toxic Plants Potentially Impacting the Health Status of Livestock in St. Kitts—A Surveillance Study

Andras-Laszlo Nagy, Francesca Caloni, Regina Tose Kemper, Sofia Gonzalez Lleras, Heather Beigh, Christian DeJean, Maurice Matthew, Georgios Paraschou

Tropical regions are characterized by exceptional biodiversity, including extremely diverse flora. Many plants produce chemical compounds that function as defense mechanisms, some of which are toxic to mammals, including livestock species. However, documentation of toxic plants in the Caribbean region remains limited. The present study aimed to identify toxic and potentially toxic plant species affecting livestock on the island of Saint Christopher (St. Kitts) through surveys of a representative number of farms acr …

03.09.2026journal-article

Student's Journal of Health Research Africa

<b>Influence of at-risk gambling on the mental well-being of the youth in Nakawa Division, Kampala District, Uganda. A cross-sectional study.</b>

Albert Louis Elwa, Clesistom Ahimbisibwe, Frank Kiyingi, Robert Oluka

Background: The football pools are still around today and are, in fact, the source of inspiration for fixed odds on gambling. To assess the influence of at-risk gambling on the mental well-being of the youth in Nakawa Division, Kampala District, Uganda. Methodology: The study employed a cross-sectional survey research design. Quantitative data were analysed using a computerised data analysis program known as the Statistical Package for Social Sciences (SPSS) version 25. Results: There was a significant but negative …

03.09.2026journal-article

Hospital Pediatrics

Prevalence and Characteristics of Mental Health Interventions Following Pediatric Hospitalization

Mariah L. DeSerisy, Julia A. Heneghan, Matt Hall, Daniel H. Choi, Leslie A. Dervan, Daniel Garros, Denise M. Goodman, Jason M. Kane, Joseph G. Kohne, Colin M. Rogerson, Nadia Roumeliotis, Vanessa Toomey, Adam C. Dziorny

BACKGROUND AND OBJECTIVES As survival after pediatric critical illness improves, attention has shifted to post–intensive care syndrome and the long-term mental health of pediatric intensive care unit (PICU) survivors, who have high rates of posttraumatic stress, anxiety, and depression. The objective of this study is to examine the rates of new mental health follow-up and psychopharmacology use among publicly insured children following PICU hospitalization, compared with those hospitalized on acute care wards. METH …

03.09.2026journal-article

Frontiers in Nutrition

The relationship between parental feeding practices and children’s health-related quality of life

Charlotte Juton, Silvia Torres, Gina Valdés-Querol, Luis Rajmil, Montserrat Fito, Santiago F. Gómez, Helmut Schröder

Background Healthy eating is essential throughout childhood and adolescence, and has been associated with better health-related quality of life (HRQoL). Healthy eating results from complex interactions, including the transmission of eating habits within families. Although parental feeding practices may influence children’s HRQoL through several plausible behavioral pathways, empirical evidence examining this association remains limited. Therefore, the objective of this study was to investigate the association betwe …

03.09.2026journal-article

Frontiers in Medicine

Case Report: Secondary syphilis with pulmonary involvement mimicking eosinophilic granulomatosis with polyangiitis — targeted next-generation sequencing as an adjunct in resolving an atypical non-exanthematous presentation

Shunjun Tang, Tiehan Zhang, Aiyi Hao, Bin Su, Bin Liu

Background The global resurgence of syphilis poses growing challenges for clinical diagnosis, particularly when atypical presentations without classic mucocutaneous lesions mimic systemic autoimmune diseases. Pulmonary involvement in secondary syphilis is rare and frequently misdiagnosed, leading to inappropriate immunosuppressive therapy. Case presentation A 24-year-old male presented with one month of inflammatory back pain and two weeks of cough, purulent sputum, and intermittent low-grade fever. He initially de …