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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
01.09.2026journal-article

Saudi Journal of Kidney Diseases and Transplantation

Chronic Dehydration in Older Adults: A Silent Threat to Healthy Aging

Tej K. Mattoo, Hong Lu

Abstract In contrast to acute dehydration, which is usually recognized through identifiable risk factors, clinical signs, and laboratory abnormalities, chronic dehydration develops insidiously and frequently goes unrecognized. This is particularly true in older adults, among whom many of its nonspecific manifestations—such as weakness, constipation, headache, dizziness, gait instability, and confusion—are often mistakenly attributed to normal aging. This population is especially vulnerable to chronic dehydration be …

01.09.2026journal-article

TAJ: Journal of Teachers Association

Health Care Seeking Behaviors among General People in the Naogaon General Hospital of Bangladesh

Al Muksit Mohammad Taufiquer Rahman, Md Aminul Islam, Shanta Roy, Maisha Rahman Mohona

Background: Health-seeking behavior is a critical determinant of health outcomes, particularly in low-resource settings like Bangladesh. Understanding why and how general people access hospital care can inform targeted interventions to reduce delays and improve service utilization. However, empirical data from secondary-level public hospitals remain limited. Objective: To assess the health care-seeking behaviors among the general population attending a district-level hospital in Bangladesh. Methods: A prospective c …

01.09.2026journal-article

Journal of the American Heart Association

Amyloid‐Related Imaging Abnormalities Summit Special Proceedings: Cardiovascular and Stroke Considerations for β‐Amyloid Immunotherapy in Alzheimer Disease

Steven M. Greenberg, Costantino Iadecola, Sherry H.‐Y. Chou, Petrice M. Cogswell, Mitchell S. V. Elkind, William J. Hicks, Caitlin Le, Deborah A. Levine, Richard Lipton, Lauren Massimo, Stephanie M. Mohl, Sudha Seshadri, Heather M. Snyder, Kristine Yaffe, Kori S. Zachrison, Robert Adams, Marc Agronin, Alireza Atri, Mary Ann Bauman, James L. Bernat, Alessandro Biffi, Sonja Blum, Thierry Bussiere, Tara C. Carlisle, Maria C. Carrillo, Gloria Chiang, Kenrick Cato, Alexander Chaitoff, Suzanne Bakken, Matthew W. Schelke, Salvador Cruz‐Flores, Janice Y. Chyou, Colin Derdeyn, Amar Dhand, David A. Evans, Cameron Gettel, Larry B. Goldstein, Joshua Grill, Makoto Ishii, Ambar Kulshrestha

Background New antiamyloid therapies (AAT) for treating patients with early Alzheimer disease (AD) have become available in the past 3 years. Although AAT can be beneficial in slowing progression of AD, they also come with potentially serious side effects, particularly for patients requiring anticoagulation or thrombolysis for cardiovascular conditions. Given that most patients with AD are older and likely to have cardiovascular risk factors, there is urgent need for additional guidance for clinicians about potenti …

01.09.2026journal-article

Comprehensive Journal of Science

اعتماد جمهور مدينة الزاوية على صفحات "فيسبوك" كمصدر للمعلومات أثناء أزمة الوقود: دراسة ميدانية

عماد عبداللطيف سالم

هدف هذا البحث إلى قياس مستوى اعتماد جمهور مدينة الزاوية على صفحات فيسبوك للحصول على معلومات أزمة الوقود، والكشف عن دوافع هذا الاعتماد، وتحديد مدى متابعة الجمهور للمعلومات المنشورة، وقياس مستوى ثقته فيها، اعتمد البحث المنهج الوصفي المسحي، واستخدم الاستبيان الإلكتروني أداة لجمع البيانات من عينة قصدية قوامها 426 مفردة من مستخدمي فيسبوك المقيمين بمدينة الزاوية ممن سبق لهم متابعة معلومات أزمة الوقود عبر الصفحات المحلية، عولجت البيانات باستخدام التكرارات والنسب المئوية، والمتوسطات الرتبية، واختبار كاي تربيع لجودة المطابق …

01.09.2026journal-article

Journal of Business, Social and Technology

Inclusive Financial Literacy for Deaf People: Accessibility Analysis of Game-Based Financial Education Media

I Gst. Agung Pramesti Dwi Putri, A.A. Istri Ita Paramitha, Ni Wayan Nanik Suaryani Taro Putri, Ni Putu Setia Pratiwi, Kadek Bagastya Adi Widyadhana

Background: Limited access to visually accessible financial education remains a barrier for deaf people in understanding financial information and making responsible economic decisions. Objective: This study aims to analyze the accessibility of a game-based financial education medium for deaf people by examining user needs, the translation of financial content into visual and interactive elements, and user experience toward the developed prototype. Methods: This study employed a descriptive-evaluative mixed methods …

04.09.2026journal-article

Sage Open Aging

From Evidence to Action: Translating Research Into Policy and Practice Communication Tools

Katherine M. Abbott, Molly Noble, John Beilenson, Christine Gherst, Jane Donahue, Kimberly Van Haitsma

Background Preference-based, person-centered care is essential to improving quality of life for older adults living in nursing homes (NHs). Communicating the rationale to implement evidence-based practices to policy makers and NH administrators amid competing priorities is challenging. Objective This article describes an initiative that developed two communication tools—a value proposition statement and a policy brief—to promote adoption of the evidence-based Preferences for Everyday Living Inventory (PELI) in NHs. …

01.09.2026journal-article

JAIDS Journal of Acquired Immune Deficiency Syndromes

Pre-ART Platelet-to-Lymphocyte Ratio and Neutrophil-to-Lymphocyte Ratio and the Risk of Non–AIDS-events, AIDS-Events, and Mortality in People With HIV

Paola Saltini, Alessandro Cozzi-Lepri, Giorgio Bozzi, Alessandro Tavelli, Giulia Marchetti, Lucia Taramasso, Sara Mazzanti, Viviana Rizzo, Andrea Antinori, Cristina Mussini, Andrea Gori, Antonella d'Arminio Monforte, Alessandra Bandera

Background: Among people with HIV (PWH) on antiretroviral therapy (ART), serious non–AIDS-events (SNAEs) are linked to inflammation. Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and lymphocyte-to-monocyte ratio (LMR) are inflammatory biomarkers. We investigated their performance in PWH. Methods: PWH enrolled in the national cohort Italian Cohort Naive Antiretrovirals who started ART over 1997–2021 with measures of NLR, PLR, and/or LMR within 6 months pre-ART (“baseline”) were included. B …

01.09.2026journal-article

Diabetes, Obesity and Metabolism

Person‐Reported and Continuous Glucose Monitoring ( CGM ) Recorded Hypoglycaemia in People With Insulin‐Treated Type 2 Diabetes and Mild to Moderate Chronic Kidney Disease; Post Hoc Analysis From the Hypo‐ METRICS Study

Julie M. B. Brøsen, Daniel Malmsiø, Patrick Divilly, Gilberte Martine‐Edith, Natalie Zaremba, Namam Ali, Rory J. McCrimmon, Simon Heller, Mark Evans, Bastiaan de Galan, Julia K. Mader, Eric Renard, Allan A. Vaag, Pratik Choudhary, Ulrik Pedersen‐Bjergaard, the HypoRESOLVE Consortium

ABSTRACT Background and Aims People with diabetes and chronic kidney disease (CKD) may be at increased risk of iatrogenic hypoglycaemia. We compared rates of sensor‐detected (SDH) and person‐reported hypoglycaemia (PRH) in people with insulin‐treated Type 2 diabetes (T2D) with and without CKD in the Hypo‐METRICS study. Materials and Method Insulin‐treated T2D patients with > 1 hypoglycaemic episode within the last 3 months wore a blinded continuous glucose monitor (CGM) and recorded PRH on the bespoke Hypo‐METRICS …

01.09.2026journal-article

Diabetes, Obesity and Metabolism

A Novel Metabolic Inflammation Index for Cardiovascular Prognosis: Evidence From Three International Cohorts in Middle‐Aged and Older Adults

Menglu Liu, Na Xu, Gengyu Sha, Yunqing Ye, Kailun Yan, Kexin Zhang, Fanyong Xu, Yi Yao, Fangshun Tan, Jidong Guo, Nuerbahati Heisha, Yuejin Yang, Jinqing Yuan, Xueyan Zhao

ABSTRACT Background Chronic inflammation and insulin resistance (IR) are key drivers of cardiovascular disease (CVD); however, their joint impact on cardiovascular risk remains poorly understood. Methods We developed the metabolic–inflammatory index (eMII) based on estimated glucose disposal rate (eGDR) in a derivation cohort (ELSA) and evaluated its transportability in two external validation cohorts (CHARLS, HRS). Multivariate Cox regression was utilised to assess the joint impact of IR and inflammation on long‐t …

04.09.2026journal-article

Age and Ageing

Effects of the ‘ReacStep’ training program on balance recovery and fall risk factors in older people: an assessor-blinded randomised controlled trial

Shivam Sharma, Carly Chaplin, Cameron Hicks, Daniel Treacy, Melanie K Farlie, Steven Phu, Natassia Smith, Hannah Gibson, Chrissie Ho, Eve Coleman, Tiffany Huang, Collen G Canning, Natalie E Allen, J C Close, Stephen R Lord, Yoshiro Okubo

Abstract Background Reactive balance training (RBT) using repeated perturbations may reduce falls; however, training methods are not easily replicated or translatable to clinical settings. This study aimed to examine the effects of a novel RBT program on balance recovery from laboratory-induced trips and slips and fall risk factors in older people using simple and low-cost equipment. Methods We conducted a randomised controlled trial involving 88 older people. An intervention group (n = 43) received the ReacStep pr …

03.09.2026journal-article

Experimental Dermatology

COCH Expression in the Hair Follicle Microenvironment Is Associated With Cortical Disulfide Bonding and Tensile Resistance in Aging Hair

Hyun Woo Joo, Gyusang Jeong, Seung Hyun Shin, Su Na Kim, Donghyun Kim, Mira Ham, Hyoung‐June Kim, Byung Cheol Park, Won‐Seok Park, Incheol Seo, Young Kwan Sung

ABSTRACT Although hair aging affects appearance and hair quality, objective biomarkers linking molecular alterations to clinically relevant mechanical properties of hair remain limited. Here, we investigated the relationships among age, hair tensile resistance, and cortical disulfide bond content. Hair shafts from healthy volunteers (20–40 years vs. > 50 years) were analysed for tensile resistance, which was measured as maximum tensile force, and disulfide bond content was assessed by Raman spectroscopy. In paralle …

01.09.2026journal-article

Shock

Aging at the Cellular Level: An Exploratory Analysis of the Effect of Age on Platelet Dynamics in Injured Patients

Genna Beattie, Bellal A. Joseph, Brenda Nunez-Garcia, Suzanna Chak, Celine Chou, Isabel Arango, Seif Elmankabadi, Karl Zoghbi, Kim Bardillon, Michelle Conte, Cedric M.V. Bainton, Joseph Cuschieri, Mitchell J. Cohen, Rachael A. Callcut, Alexander T. Fields, Lucy Z. Kornblith

Introduction: Increasing chronological age drives dynamic changes in platelet functionality, bringing unique biologic challenges to the injured older adult. While platelets play an indispensable role in injury response, the impact of age on platelet dynamics after injury remains elusive. We examine the associations of age and platelet dynamics for injured patients not on antiplatelet therapy, hypothesizing that aging is associated with decreases in platelet count and function in injured patients. Methods: We perfor …

01.09.2026journal-article

Journal of Neural Engineering

A fused minimum spanning tree framework reveals large-scale cortical network reorganization during dual-task standing in older adults

Yi-Ching Chen, Wei-Min Huang, Ing-Shiou Hwang

Abstract Objective. Dual-task standing challenges postural regulation in older adults, but the associated cortical network reorganizations remain incompletely characterized. This study investigated how a visuomotor dual-task modulates postural dynamics and cortical network during unstable standing. Approach. Twenty-six community-dwelling older adults performed foam-surface standing under single-task and visuomotor dual-task conditions. Postural dynamics were quantified using center-of-pressure (COP) measures and st …

01.09.2026journal-article

Frontiers in Neurology

Compound Congrong Yizhi capsule partially remodels the fronto-retrosplenial-hippocampal memory circuit in vascular dementia rats

Ying Zhang, Yefei Wang, Xuemei Liu, Baoxin Chen, Shaozhen Ji, Jiayu Duan, Junya Liao, Yihan Wang, Xianglan Jin

Background Progressive cognitive impairment in vascular dementia (VaD) is increasingly linked to brain network disruption, or “disconnection syndrome.” Although Compound Congrong Yizhi Capsule (CCYC), a marketed Chinese patent medicine approved in China for vascular cognitive disorders, has been studied in terms of therapeutic efficacy and molecular targets, these approaches do not directly explain how this multi-target intervention modulates brain functional organization. Resting-state functional magnetic resonanc …

02.09.2026journal-article

Journal of Pineal Research

ENLIGHTENme: Translating the Benefits of Self‐Administered Daytime Light Supplementation to Older Adults in the Real World

Débora B. Constantino, Flavia Baccari, Leonardo Caporali, Valerio Carelli, Giulia Amore, Marijke Gordijn, Toomas Haller, Chiara La Morgia, Anne Landvreugd, Marina Marinelli, David McDaid, Monika Nõmm, Francesco Nonino, Martina Romagnoli, Martino Schettino, Corrado Zenesini, Meike Bartels, Debra J. Skene, Daan R. van der Veen

ABSTRACT Controlled studies have demonstrated that light supplementation benefits circadian entrainment, sleep and mood. Translating these findings into effective, real‐world usage of light supplementation is, however, challenging because naturalistic and supplemental light exposure are shaped by personal habits and environmental light conditions. Bridging this translation gap is especially critical for older adults, given the reduced ocular light sensitivity associated with natural ageing, which exacerbates low da …

01.09.2026journal-article

Journal of Public Health and Development

Rethinking successful aging concepts: Insights from a culturally grounded model among older adults in Odisha, India

Aditya Narayan Das, Smita Mishra Panda, Anjali Dash

Despite the widespread use of the biomedical model of successful aging, it overlooks the cultural and lived experiences of older adults in low- and middle-income countries, such as India. Therefore, this cross-sectional study aims to empirically test a culturally grounded model of successful aging in India. Using a multistage stratified sampling with a structured interview schedule, this study used 600 older adults aged 60 years and above from Odisha, India. We used a dichotomous measure of successful aging, which …

01.09.2026journal-article

Vasa

Vascular medicine in older adults – A call for structured cooperation to improve care

Gerald Kolb, Farzin Adili, Michael Denkinger, Gesine Dörr, Ursula Müller-Werdan, Oliver J. Müller, Christoph Ploenes, Alexander Oberhuber, Barbara Rantner, Markus Steinbauer, Norbert Weiss, Rainer Wirth, Hartmut Görtz

Summary: The patient population treated by vascular medicine is becoming older, which goes along with an increasing number of patients presenting with frailty syndrome. The level of frailty determines the outcomes after vascular surgery or interventions. This position paper written by the German Society for Vascular Surgery and Vascular Medicine, the German Society for Geriatrics, and the German Society for Angiology – Society for Vascular Medicine summarizes the current evidence on the impact of frailty on the out …

01.09.2026journal-article

Journal of Comparative Effectiveness Research

Clinical effectiveness of a digitally delivered balance program for older adults: a nonrandomized controlled trial

Folasade Phillips, Sandhya Yadav, Cynthia Castro Sweet, Rachel NS Foster Kirk, Mindy Hong, Samuel Mink, Jeffrey Krauss

Aim: To evaluate the clinical effectiveness of a digitally delivered balance program relative to an attention-control comparison group in older adults at risk for falls. Materials & methods: This nonrandomized controlled trial recruited adults aged 65 years and older with moderate-to-high fall risk. Participants were assigned to a digital balance program (exercise therapy, education and health coaching) or an attention-control group (education materials). Outcomes were assessed via self-report surveys at baseline a …

03.09.2026journal-article

Health Science Reports

A Systematic Review of Health Literacy in People Living With Parkinson's Disease

Saleha Mahomed‐Kola, Jennifer Watermeyer, Aline Ferreira‐Correia

ABSTRACT Background and Aim Health literacy (HL) is important for People with Parkinson's Disease (PwPD), as the complexity of symptom management requires individuals to understand and apply health information across diverse healthcare contexts. This systematic review aims to provide a narrative synthesis of worldwide evidence on HL in PwPD by synthesizing overarching themes that demonstrate the ways in which HL affects disease management. Methods A narrative, thematic synthesis of the included studies was done. Ar …

01.09.2026journal-article

BMC Psychology

A latent profile analysis and network analysis of depression and anxiety symptoms among older adults living alone

Qi Hui, Yuan Li, Rongjuan Zhu, Bowen Luo, Ying Liang, Xiang Che, Xuqun You

Abstract Objectives Living alone is a well-recognized risk factor in aging, associated with adverse psychological outcomes including depression and anxiety. However, the heterogeneity of depression-anxiety comorbidity patterns and inter-symptom relationships remain understudied in older adults living alone. Methods A total of 11,632 adults aged ≥ 60 years were included from the 2018 Chinese Longitudinal Healthy Longevity Survey. Depressive and anxiety symptoms were assessed with the Center for Epidemiologic Studies …

01.09.2026journal-article

Neurosurgical Focus

Longitudinal functional trajectory and surgical outcomes after intracranial meningioma resection: implications for surgical decision-making in older patients

Neslihan Nisa Gecici, Jake Littman, Ahmed Habib, Walaa Hamza, Maged T. Ghoche, Rivka R. Colen, Kalil G. Abdullah, Paul A. Gardner, Georgios A. Zenonos, Pascal O. Zinn

OBJECTIVE As the population ages, meningiomas are increasingly encountered in older patients, yet longitudinal functional outcomes following surgery across age groups remain incompletely characterized. This study evaluated age-related differences in clinical and tumor characteristics, functional trajectory, and surgical outcomes. METHODS This was a retrospective cohort study of 396 consecutive patients who underwent surgery for intracranial meningiomas at a single academic center between January 2023 and September …

02.09.2026journal-article

American Journal of Alzheimer's Disease & Other Dementias®

Are the “Serial 7s” and Spelling Backwards Tasks From the MMSE Comparable in MCI and Dementia?

Edoardo Nicolò Aiello, Giulia De Luca, Arianna Moreschi, Beatrice Curti, Francesco Cazzini, Andrea Cerri, Selene Saba, Valerio Patisso, Alessio Maranzano, Vincenzo Silani, Nicola Ticozzi, Federico Verde, Barbara Poletti

We explored the comparability of the “Serial 7s” (S7) and Spelling Backwards (SB) tasks from MMSE in 313 patients with MCI ( N =54) and dementia ( N =259) due to Alzheimer’s disease (AD), frontotemporal lobar degeneration, Lewy body disease, non-AD degenerative (NADD), chronic cerebrovascular disease (CVD) or mixed (AD+CVD) etiologies. Although the two tasks were significantly associated with each other ( r =.54), a two one-sided test revealed that they were not statistically equivalent. Consistently, a linear mixe …

01.09.2026journal-article

Frontiers in Public Health

Healthcare accessibility and financial risks for unmet health needs of the older adult population in the republic of Serbia

Nikola Savić, Slobodanka Bogdanović Vasić, Branimirka Aranđelović, Katarina Pavić, Sanja Kocić, Aleksandra Arnaut, Milena Zlatanović, Jelena Stojčević-Maletić, Svetlana Ristić

Background and objectives Unmet healthcare needs indicate gaps between healthcare services considered necessary and those actually received, reflecting the accessibility of the health system. This study aimed to examine the frequency of unmet healthcare needs and identify Andersen model predictors of unmet needs due to financial and other objective reasons among older adults in Serbia. Materials and methods This cross-sectional study used data from the 2019 Serbian National Health Survey, conducted from October to …