Alle Themen: neue Gesundheitspublikationen – Seite 161

08.09.2026journal-article

Journal of Clinical Medicine

Early Lean Tissue Loss and Nutritional Challenges Following Sleeve Gastrectomy in a Kidney Transplant Recipient: A Case Report

Nida Yıldız, Halil Coşkun, Serpil Görçin, Nazlı Batar, Şule Arslan, Halit Tanju Besler

Background/Objectives: Obesity after kidney transplantation impairs graft function, but the time course of lean tissue loss after sleeve gastrectomy in this population is poorly described. Methods: A 46-year-old woman underwent sleeve gastrectomy five years after kidney transplantation and was followed for 33 months with bioelectrical impedance analysis (BIA) and three 24-h dietary recalls per visit. Results: Weight fell from 103.4 to 69.4 kg by month 6, with mild regain to 71.9 kg at month 33. BIA-derived fat-free …

08.09.2026journal-article

Biology

Baicalin Modulates Hepatic Lipid Metabolism and Improves Intestinal Health in White-Feathered Broilers

Junxin Li, Xiaowei Huang, Yana Li, Yu Zheng, Shizhong Zhang, Bohan Zheng, Qinjin Li, Xiaohong Huang, Zhaoyan Lin

Liver and intestinal health govern the production performance of broilers. Baicalin (BA) is a flavonoid extracted from the dried roots of Scutellaria baicalensis and possesses a wide range of biological activity. In this study, 66 one-day-old white-feathered broilers were selected and randomly divided into two groups. Broilers in the control group were fed a basal diet, whereas the BA group received the basal diet supplemented with 100 mg/kg BA. The results showed that BA supplementation markedly elevated the antio …

08.09.2026journal-article

Journal of Clinical Psychology

The Hospital Anxiety and Depression Scale in People Living With HIV: A Validity Study in a Hard‐to‐Reach Population

Helena Garrido‐Hernansaiz, Manuel Martín‐Fernández, Douglas J. Boegaerts

ABSTRACT Objectives While the Hospital Anxiety and Depression Scale (HADS) is widely used in diverse populations, countries, and languages, its scores' factor structure remains under debate. Only three studies have examined this in People Living with HIV (PLWH), with none conducted in Europe, Latin America, or Spanish‐speaking samples. This study aimed to test five possible structural models of the HADS scores (one‐, two‐, and three‐factor, and bifactor models with two and three factors) in Spanish‐speaking PLWH, a …

08.09.2026journal-article

Clinical and Translational Gastroenterology

Greener Choices in Biliary Imaging: A Prospective Carbon Footprint Comparison of EUS versus MRCP for Intermediate-Likelihood Choledocholithiasis

Hardik Rughwani, Nitin Jagtap, David M. de Jong, Abhishek Tyagi, Tharani Putta, Ashirwad Pasumarthy, Abul Khair Khan, Rakesh Kalapala, Mohan Ramchandani, Sundeep Lakhtakia, D. Nageshwar Reddy

Introduction: Healthcare accounts for nearly 5% of global greenhouse gas (GHG) emissions, and medical imaging is among its most energy-intensive activities. For intermediate-likelihood common bile duct (CBD) stones, endoscopic ultrasound (EUS) and magnetic resonance cholangiopancreatography (MRCP) are both guideline-endorsed with comparable diagnostic accuracy, yet their environmental costs have never been directly compared. Methods: In this prospective study, we measured the per-procedure carbon footprint of EUS a …

08.09.2026journal-article

Menopause

Role of coronary artery calcium in the association between hormone therapy status and incident death and cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis

Rachelle Bishay, Keishi Ichikawa, April Kinninger, Srikanth Krishnan, Nathan D. Wong, Erin D. Michos, Ahmed Ghanem, Marziyeh Bagheri, Hossein Hamidi, Matthew J. Budoff

Objective: To investigate whether coronary artery calcium (CAC) modifies the association between hormone therapy (HT) use and cardiovascular disease (CVD) events. Methods: A total of 3,235 female participants free of clinical CVD at baseline were included from the Multi-Ethnic Study of Atherosclerosis and monitored for incident CVD. HT status was self-reported and categorized as never, former, and current users. Cox proportional hazards regression models were fit to examine the relationships between HT and CVD outc …

08.09.2026journal-article

JMIR Formative Research

Evaluation of a Decision Mining Tool for Nursing Quality Improvement by Hospital Nurses: Theory-Guided Qualitative Study

Matthijs Berkhout, Jobbe P L Leenen, Koen Smit, Thijs van Houwelingen

Abstract Background Clinical decision support systems (CDSSs) are widely implemented in hospitals, yet their uptake in nursing practice remains inconsistent. While electronic health records continuously capture nursing decision data, these data are rarely used to support structured quality improvement. Decision mining offers a novel approach by reconstructing and visualizing decision logic from clinical decision logs to support retrospective reflection and protocol evaluation rather than real-time alerting. Before …

08.09.2026journal-article

Orthopaedic Surgery

Kinematic Alignment in TKA Using the Contralateral Healthy Knee as Reference: A Combined Finite Element and Clinical Analysis

Lingce Kong, Wei Lin, Huijun Kang, Muchen Yu, Ming Li, Chenyue Xu, Fei Wang

ABSTRACT Objective Mechanical alignment (MA) and kinematic alignment (KA) are common total knee arthroplasty (TKA) strategies. Patients with bilateral knee osteoarthritis lack a precise individualized alignment reference, whereas those with unilateral OA have a potential reference from the contralateral healthy knee. This study proposes a natural KA (NKA) strategy referencing the contralateral healthy knee and compares biomechanical and clinical outcomes of MA, KA, and NKA for TKA. Methods Finite element models (ne …

08.09.2026journal-article

Revista Ibero-Americana de Humanidades, Ciências e Educação

USO INDISCRIMINADO DE ESTEROIDES ANABOLIZANTES E SUAS REPERCUSSÕES SOBRE A SAÚDE CARDIOVASCULAR EM ADULTOS JOVENS

Gabrielle Ramos de Carvalho, Emanuelle Oliveira da Silva, Bianca da Silva Cardoso Porto, Matheus Ramos de Carvalho, Ramon Fraga de Souza Lima

A saúde cardiovascular constitui um pilar fundamental para a manutenção do bem-estar metabólico, físico e mental. Embora as doenças cardiovasculares sejam tradicionalmente associadas ao envelhecimento, observa-se um aumento progressivo de sua incidência entre indivíduos mais jovens, impulsionado principalmente por fatores relacionados ao estilo de vida e pelo uso não terapêutico de substâncias exógenas, como os esteroides anabolizantes. O uso desses hormônios está vinculado à busca por padrões estéticos, com o obje …

08.09.2026journal-article

Australian and New Zealand Journal of Obstetrics and Gynaecology

Clinical Pregnancy and Live Birth Outcomes From 445 Vitrified Oocyte Cycles in Australia

Anna Dalton, Alicia Filby, Luk Rombauts, Kelton Tremellen, Ross Turner, Michael Costello, Deirdre Zander‐Fox, Leanne Pacella‐Ince, Juliette Koch

ABSTRACT Aim To describe the outcomes for women in Australia who proceed with vitrified oocyte‐thaw (VOT) cycles to achieve pregnancy. Method Our descriptive retrospective cohort study of 445 medical and personal VOT cycles over 12 years (2009–2021) at 11 Australian IVF clinics assessed outcomes in oocyte survival, ICSI fertilisation rate, embryo utilisation rate, clinical pregnancy rate (CPR) and live birth rate (LBR), using age‐stratified data (≤ 35, 35–39 and ≥ 40 years). Results Women were on average 36.8 years …

08.09.2026journal-article

Advanced Science

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

Anlai Zou, Xiaoxue Zhu, Runhan Zhu, Chengchu Xue, Qinyu Zhang, Mengke Li, Ting Yu, Yuzhen Gao, Zhi Ruan, Ying Fu, Yunlei Xianyu, Jun Zhang

ABSTRACT Sepsis remains a leading cause of mortality because current therapies fail to address its dynamically evolving pathophysiology, in which infection, oxidative stress, and immune dysfunction emerge sequentially and interdependently. Here, we present a pH‐adaptive nanozyme platform (MICP@HG) that orchestrates stage‐specific antibacterial and immunomodulatory activities throughout sepsis progression. The platform integrates near‐infrared imaging, catalytic therapy, and immune regulation into a single construct …

08.09.2026journal-article

Nuclear Medicine Communications

Fluorine-18 fluorodeoxyglucose PET/computed tomography-based radiomics for predicting risk groups, tumor stage, and capsular and fat tissue invasion in thymomas

Ebru Tatci, Büşra Bozca, Kayacan Dizdar, Tuba İnal Cengiz, Nesrin Gürcay, Leyla Nesrin Acar, Ülkü Yilmaz, Özlem Özmen, Pinar Tari, Nur Aydinbelge Dizdar

Purpose This study aimed to investigate the predictive value of fluorine-18 fluorodeoxyglucose PET/computed tomography (CT) based radiomics in patients with thymoma for risk stratification and tumor staging, including capsular and fat tissue invasion. Methods A total of 67 (50 for training and 17 for validation) patients with thymoma were analyzed. Thymomas were categorized as low risk (types A, AB, and B1) or high risk (types B2 and B3) and as early stage (I–II) or advanced stage (III–IV). PET- and CT-derived radi …

08.09.2026journal-article

Borneo Nursing Journal (BNJ)

Hubungan Sikap Ibu Dengan Pemberdayaan Ibu Hamil Dalam Melakukan Deteksi Dini Kecemasan Pada Kehamilan Dipuskesmas Kombos Kota Manado

Rasnun Ruslan, Adhe Lisna G. Sasiwi, Irne Wida Desiyanti, Nelawati Radjamuda

Kecemasan pada ibu Hamil merupakan salah satu masalah psikologis yang dapat terjadi selama kehamilan dan berpengaruh terhadap Kesehatan ibu dan janin. Pemberdayaan ibu hamil diperlukan untuk menigkatkan kemampuan dalam megenali dan melakukan deteksi dini kecemasan, sedangkan sikap ibu merupakan salah satu factor yang dapat memengaruhi pemberdayaan tersebut. Tujuan dari penelitian ini Adalah untuk mengetahui bagaimana presepsi ibutantang kemampuang mereka untuk mendeteksi kecemasan selama kehamilan sejak dini di Pus …

08.09.2026journal-article

Earthquake Spectra

Nonlinear Response History Soil–Structure Interaction Studies on UCSF Health Helen Diller Hospital Building

Andres Rodriguez‐Burneo, Marios Panagiotou, José I. Restrepo, Mina Riad, Daniel Tunick, Eleanor Siow, Elie Elkhoury, Anthony Giammona, Jonathan Buckalew, Sudharshan Navalpakkam, Michael Gemmill

The ASCE/SEI 7‐16 standard contains prescriptive provisions for soil–structure interaction (SSI). However, SSI is rarely incorporated into nonlinear response history analyses, particularly in performance‐based seismic design. This paper examines the seismic response of the $4.3 billion University of California, San Francisco Health Helen Diller Hospital Building, explicitly considering SSI effects. The 258‐foot‐tall structure comprises 15 aboveground levels and two basement levels and is supported by a pile foundat …

08.09.2026journal-article

Frontiers in Dental Medicine

Diagnostic performance of artificial intelligence in oral squamous cell carcinoma detection: a higher-order evidence synthesis through umbrella review and meta-meta-analysis

Praveen Jodalli, Vineet Vinay, Mahesh Chavan, Ramya Shenoy, Utkarsha Deshpande, Sam Thomas Kuriadom, Apurva Mishra, Raghavendra M. Shetty

Background The integration of AI into oral squamous cell carcinoma (OSCC) diagnostics is a major milestone for digital dentistry and computational pathology, enabling faster, highly accurate detection. While numerous systematic reviews have attempted to synthesize this burgeoning evidence, their conclusions remain discordant and methodological quality varies substantially. Aim This umbrella review undertakes a rigorous synthesis of systematic review evidence to establish definitive accuracy metrics, evaluate method …

08.09.2026journal-article

Clinical Nuclear Medicine

Extraskeletal Ewing Sarcoma Involving the Abdominal Cavity and Retroperitoneum on 18F-FDG PET/CT and 68Ga-FAPI-04 PET/CT

Qinglin Lei, Luping Huang, Linjia Zhou, Ke Xiang, Lin Qiu

Primary extraosseous Ewing sarcoma located in the abdominal cavity and retroperitoneum is rare. We report the 18 F-FDG PET/CT and 68 Ga-FAPI-04 PET/CT imaging findings of intra-abdominal Ewing sarcoma. The mass showed mild FDG uptake and avid FAPI uptake.

08.09.2026journal-article

Frontiers in Psychiatry

Real-world adherence, healthcare resource utilization, and costs following a transition to aripiprazole once every 2 months among patients diagnosed with bipolar I disorder in the United States

Soma S. Nag, Annette Urganus, Karimah S. Bell Lynum, Norman Atkins, Onur Baser, Katarzyna Rodchenko, Shivanshu Awasthi, Kristine Harrsen

Introduction Transitioning from oral to long-acting injectable (LAI) antipsychotics may improve adherence and reduce healthcare resource utilization (HCRU) in patients living with bipolar I disorder (BP-I), with potentially greater improvements with LAIs with dosing intervals longer than 1 month. Aripiprazole monohydrate is available as LAI formulations administered once-monthly [aripiprazole once-monthly (AOM)] or once every 2 months (aripiprazole 2-month ready-to-use [Ari 2MRTU]). This pre-post analysis described …

08.09.2026journal-article

RSV

Mental Health of Healthcare Professionals: Working Conditions, Associated Factors, and Challenges for Care

Anderson Machado Teixeira Dias, Maria Aparecida de Almeida Araújo, Átila Barros Magalhães, Erica Souza da Silva, Helena Vilela da Cunha, Maria Marlene Fernandes, Pamella Caroline Alves Tinoco, Vera Lucia dos Santos

The mental health of healthcare professionals has become an increasingly important public health and occupational health concern. Healthcare workers are exposed to intense workloads, emotional demands, long working hours, staff shortages, organizational pressures, violence, ethical conflicts, and continuous responsibility for human lives. These conditions may contribute to stress, burnout, anxiety, depression, sleep disturbances, moral distress, and other forms of psychological suffering. This academic essay discus …

08.09.2026journal-article

Journal of Oral Rehabilitation

Orofacial Myofunctional Therapy for Feeding and Swallowing in Children From Four to 12 Years: What Does the Evidence Show? A Systematic Review

Danielle Carey, Robyn Merkel‐Walsh, Phoebe Burrage, Melissa Hadlow, Ghidaa Hasan A. Alrehaily, Raymond J. Tseng, Sharon Smart

ABSTRACT Background Orofacial Myofunctional Therapy (OMT), a subtype of oral motor therapy, applies neuromuscular re‐education techniques to address orofacial myofunctional disorders impacting breathing, sleeping, speaking, eating and swallowing due to atypical orofacial muscle function and structural anomalies. OMT is delivered by licensed professionals within their scope of practice. While some forms of oral motor therapy are passive and can be applied at any age, OMT is volitional and appropriate generally for c …

08.09.2026journal-article

Clinical and Experimental Dental Research

Association of Treatments With Prevalence and Incidence of Periodontitis

Anna Liisa Suominen, Tuomas Saxlin, Marja‐Leena Lamidi, Virva Vänttinen, Johanna Pasanen, Tiina Laatikainen

ABSTRACT Objectives The aim was to evaluate how treatment supplied in public oral health care services is associated with the prevalence and incidence of periodontitis. Methods The data for this study comprised patients aged 20 years or older who had visited publicly funded oral health care services in the Wellbeing Services County of North Karelia (Siun sote) during the years 2021–2022 ( N = 50,469). These patients were retrospectively followed in the patient register starting from 2014. Associations of treatments …

08.09.2026journal-article

Communications Medicine

Multi-omic profiling reveals antibody-drug conjugate targetability in ovarian cancer

Elsi Pöllänen, Taru A. Muranen, Alexandra Lahtinen, Kaiyang Zhang, Daria Afenteva, Anna Pirttikoski, Susanna Holmström, Yilin Li, Kari Lavikka, Jaana Oikkonen, Jenni Söderlund, Johanna Hynninen, Anni Virtanen, Sampsa Hautaniemi

Abstract Background Antibody-drug conjugates (ADCs) represent a promising precision medicine approach for difficult-to-treat cancers, yet the spatial, temporal, and cellular heterogeneity of clinically approved ADC targets in ovarian high-grade serous carcinoma (HGSC) remains incompletely defined. Methods We analyzed bulk RNA-sequencing, single-cell RNA-sequencing, and whole-genome sequencing data from 867 samples across 304 patients enrolled in the real-world, observational DECIDER cohort to systematically evaluat …

08.09.2026journal-article

System Dynamics Review

Using Systems Archetypes in Public Health: A Review Connecting System Dynamics Literature and Public Health Applications

Loes Crielaard, Luc Hagenaars, Jillian O'Mara, Mary Nicolaou, Wilma Waterlander, Karien Stronks

ABSTRACT Systems archetypes represent typical system structure‐behaviour combinations that can be “diagnosed” across different systems to identify potential leverage points. This review examined their history and value based on foundational system dynamics literature to reflect on public health applications. We found that archetypes help generate hypotheses about leverage points and unintended consequences of interventions, but two methodological considerations emerged. First, archetypes help systematise the formul …

08.09.2026journal-article

Annals of Clinical and Translational Neurology

Clinical Impact of MGMT Promoter Methylation in IDH ‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui

ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding. Methods A total of 558 patients with WHO grade 2–3 IDH‐mutant gliomas were retrospectively analyzed. MGMT promoter methylation was quantified by pyrosequencing. Survival outcomes were assessed using Kapla …

08.09.2026journal-article

International Journal For Multidisciplinary Research

Effectiveness of Sociodrama on Knowledge Regarding Good Touch and Bad Touch Among School Age Children in Selected Schools at Sultanpur, Uttar Pradesh Khushi Gupta¹, Swati Singh¹, Damini Gaur¹, Anshika Maurya¹, Anamika Singh¹, Dr. Mariamma c John2 ¹B.Sc. Nursing Final Year, Sultanpur Institute of Nursing and Paramedical Sciences, Sultanpur, Uttar Pradesh. 2Principal, Sultanpur Institute of Nursing and Paramedical Sciences, Saifullaganj, Sultanpur, Uttar Pradesh

Khushi Gupta, Swati Singh, Damini Gaur, Anshika Maurya, Anamika Singh, Mariamma John

Abstract Background of the Study: Child sexual abuse is a serious child-protection and public-health concern. Limited knowledge about personal safety and safe and unsafe touch may increase children's vulnerability. Interactive educational approaches such as sociodrama can provide opportunities for children to observe, discuss, practice, and respond to safety situations. The present study assessed the effectiveness of sociodrama on knowledge regarding good touch and bad touch among school age children in selected sc …

08.09.2026journal-article

Maternal-Fetal Medicine

Assessing the Uptake of the Core Outcome Set in Randomized Controlled Trial Registrations for the Treatment of Pre-eclampsia Before and After Its Publication

Kailibinuer Ailimu, Ziyan Wang, Wenqiang Li, Nanxi Jia, Kexin Cao, Lin Zeng

Abstract Objective: To analyze the uptake of the PE COS in randomized controlled trial (RCT) registrations before and after its publication and examined factors associated with its uptake. Methods: PE trials were retrieved from the World Health Organization International Clinical Trials Registry Platform. Two independent reviewers screened for inclusion and extracted data in a masked, duplicate fashion. Trial characteristics and outcomes listed in registry entries were retrieved by reviewing their original registra …

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Aktuelle Forschung nach Fachgebiet

Early Lean Tissue Loss and Nutritional Challenges Following Sleeve Gastrectomy in a Kidney Transplant Recipient: A Case Report

Baicalin Modulates Hepatic Lipid Metabolism and Improves Intestinal Health in White-Feathered Broilers

The Hospital Anxiety and Depression Scale in People Living With HIV: A Validity Study in a Hard‐to‐Reach Population

Greener Choices in Biliary Imaging: A Prospective Carbon Footprint Comparison of EUS versus MRCP for Intermediate-Likelihood Choledocholithiasis

Role of coronary artery calcium in the association between hormone therapy status and incident death and cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis

Evaluation of a Decision Mining Tool for Nursing Quality Improvement by Hospital Nurses: Theory-Guided Qualitative Study

Kinematic Alignment in TKA Using the Contralateral Healthy Knee as Reference: A Combined Finite Element and Clinical Analysis

USO INDISCRIMINADO DE ESTEROIDES ANABOLIZANTES E SUAS REPERCUSSÕES SOBRE A SAÚDE CARDIOVASCULAR EM ADULTOS JOVENS

Clinical Pregnancy and Live Birth Outcomes From 445 Vitrified Oocyte Cycles in Australia

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

Fluorine-18 fluorodeoxyglucose PET/computed tomography-based radiomics for predicting risk groups, tumor stage, and capsular and fat tissue invasion in thymomas

Hubungan Sikap Ibu Dengan Pemberdayaan Ibu Hamil Dalam Melakukan Deteksi Dini Kecemasan Pada Kehamilan Dipuskesmas Kombos Kota Manado

Nonlinear Response History Soil–Structure Interaction Studies on UCSF Health Helen Diller Hospital Building

Diagnostic performance of artificial intelligence in oral squamous cell carcinoma detection: a higher-order evidence synthesis through umbrella review and meta-meta-analysis

Extraskeletal Ewing Sarcoma Involving the Abdominal Cavity and Retroperitoneum on 18F-FDG PET/CT and 68Ga-FAPI-04 PET/CT

Real-world adherence, healthcare resource utilization, and costs following a transition to aripiprazole once every 2 months among patients diagnosed with bipolar I disorder in the United States

Mental Health of Healthcare Professionals: Working Conditions, Associated Factors, and Challenges for Care

Orofacial Myofunctional Therapy for Feeding and Swallowing in Children From Four to 12 Years: What Does the Evidence Show? A Systematic Review

Association of Treatments With Prevalence and Incidence of Periodontitis

Multi-omic profiling reveals antibody-drug conjugate targetability in ovarian cancer

Using Systems Archetypes in Public Health: A Review Connecting System Dynamics Literature and Public Health Applications

Clinical Impact of MGMT Promoter Methylation in IDH ‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Assessing the Uptake of the Core Outcome Set in Randomized Controlled Trial Registrations for the Treatment of Pre-eclampsia Before and After Its Publication