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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
01.09.2026journal-article

International Journal of Athletic Therapy and Training

Neuromuscular Training Programs for Injury Reduction in Adolescent Female Running Athletes: A Critically Appraised Topic

Monica Queen, Emily Elgas, Nina German, Alexandra Green, Nicole Rogers, Kellie C. Huxel Bliven

Introduction : More females are competing at younger ages in running-intensive sports. Given their increased risk for sport-related lower-extremity (LE) injury, it is important to identify effective prevention programs at reducing injury rates in this population. Focused Clinical Question : Are neuromuscular exercise-based programs effective at reducing injury in adolescent females who participate in running-intensive sports compared to a conventional-based program? Summary of Findings : Three randomized controlled …

01.09.2026journal-article

مجلة ابن خلدون للدراسات والأبحاث

الأفعال الكلامية في ديوان "وحي الحرمان" لعبد الله الفيصل في ضوء نظرية أوستن: دراسة لسانية تداولية

رنا الرويلي, باسل الزعبي

هدفت الدراسة إلى تحليل الفعل التأثيري في ضوء نظرية الأفعال الكلامية عند أوستن في ديوان الأمير عبد الله الفيصل وحي الحرمان، والكشف عن الأثر الذي يُحدثه الخطاب الشعري في المتلقي من خلال مقاربة لسانية تداولية تستند إلى مستويات الفعل الكلامي: القولي، والإنجازي، والتأثيري. واعتمدت الدراسة المنهج الوصفي التحليلي، القائم على استقراء النصوص الشعرية في الديوان وتصنيفها وفق هذه المستويات، مع مراعاة السياقات اللغوية والمقامية التي وردت فيها. وتوصلت الدراسة إلى أن السياق يؤدي دورًا محوريًا في تحديد المقاصد الإنجازية للألفاظ ال …

01.09.2026journal-article

Journal of Cell Communication and Signaling

Mechanobiological feedback loops and quantitative decision thresholds in organ fibrosis: Translational principles for antifibrotic therapy

Amedeo Lonardo, Ralf Weiskirchen

Abstract Multiorgan fibrosis is a complex, maladaptive response to chronic injury, where the extracellular matrix (ECM) shifts from serving merely as a structural framework to becoming an active, sustained contributor to disease progression. We propose a unifying mechanobiological framework in which chronic injury promotes fibroblast activation and ECM remodeling, whereas the stiffened and remodeled ECM feeds back through integrins, mechanosensitive ion channels, collagen receptors, and Hippo‐YAP/TAZ signaling to s …

01.09.2026journal-article

Applied Psychophysiology and Biofeedback

Evaluating the Efficacy of Biofeedback in Pain Management and Rehabilitation of Sports Injuries: A Systematic Review of Randomized Controlled Trials

Andrei Mateus Delgado Viana, Neha Pirwani, Attila Szabo

Abstract To evaluate the effectiveness of biofeedback interventions for pain management and rehabilitation outcomes in athletes and individuals with sports-related injuries. Systematic review of randomized controlled trials. A systematic literature search was conducted in eight electronic databases: PubMed, Google Scholar, Web of Science, Scopus, ProQuest, PEDro, SPORTDiscus, and the Cochrane Central Register of Controlled Trials. Searches were completed in September 2024 and updated in November 2025. Randomized co …

01.09.2026journal-article

National Journal of Community Medicine

Quality of Life and Its Determinants among Patients on Vitamin K Antagonist Therapy in India: A Baseline Cross- Sectional Analysis

Janet Prameela Dsouza, Jyothi Chakrabarty, Padmakumar Ramachandran, Baby S Nayak, Elsa Sanatombi Devi, Vasudeva Guddattu, Judith Angelitta Noronha Noronha

Background: Vitamin K Antagonist (VKA) therapy has been extensively recommended for years to prevent thromboembolic disorders. The continued use of this treatment emphasizes its clinical importance across healthcare settings, particularly in resource-limited countries such as India. Chronic use of this therapy can impact patients’ QOL owing to treatment-related burden. Given that limited data are available related to the QOL of patients on VKA therapy at tertiary referral hospitals in the region, this study was und …

01.09.2026journal-article

Journal of Sport Rehabilitation

Sport Injury–Related Growth and Quality of Life Trajectories in Young Athletes After Anterior Cruciate Ligament Reconstruction: A Mixed Methods Study

Hana Marmura, Nicolette Garcia, Lesley Kukoly, Dianne M. Bryant, Julian A. Feller, Lachlan Batty, Kate E. Webster, Haydn Klemm, Jodie A. McClelland, Alan M.J. Getgood

Context : The purpose of this study was to describe young athletes’ trajectories of perceived quality of life (QOL) following anterior cruciate ligament injury and reconstruction, and to explore how athletes conceptualize QOL during recovery. Design : A mixed methods study integrating quantitative QOL trajectories with qualitative description of athletes’ individual experiences. Methods : Semistructured interviews were conducted with 13 Australian athletes (mean age: 21, 7 males and 6 females) 1-year after anterior …

01.09.2026journal-article

Nanotechnology

Targeted therapy of colon cancer with aptamer-functionalized albumin nanoparticles loaded with disulfiram

Yacong An, Zhen Yu, Ting Li, Xundou Li, Qiping Jiang

Abstract Chemotherapy remains the primary treatment for most patients with metastatic colorectal cancer (mCRC), yet its efficacy is often limited by severe adverse effects. Drug repurposing offers a promising strategy to accelerate oncology drug development. Disulfiram (DSF), a licensed anti-alcoholism agent, has demonstrated broad-spectrum anticancer activity in preclinical models. However, its clinical translation for oncology is hindered by poor aqueous solubility, rapid metabolism, and lack of tumor selectivity …

01.09.2026journal-article

Mediterranean Journal of Hematology and Infectious Diseases

Fatal disseminated fusariosis during induction therapy for adult acute lymphoblastic leukemia in a patient with prior multiple myeloma

Sara Alberti, Gianluca Cavallaro, Alessandra Tebaldi, Paola Tebaldi, Maria Chiara Finazzi, Anna Grassi, Monica Galli, Laura Paris, Paola Stefanoni, Francesca Valsecchi, Alessandro Rambaldi, Federico Lussana

Invasive fungal infections are a major cause of morbidity and mortality in patients with hematologic malignancies, particularly during prolonged neutropenia and intensive chemotherapy. In acute lymphoblastic leukemia (ALL), prophylaxis is challenging because mold-active azoles interact with vinca alkaloids and may increase hepatotoxicity with asparaginase, whereas provide incomplete coverage against Aspergillus spp. and rare molds such as Fusarium spp. We report a fatal case of proven cutaneous invasive fusariosis …

01.09.2026journal-article

Microbiology Spectrum

Clinical impact of metagenomic next-generation sequencing for pathogen identification and guided therapy in pediatric intensive care unit patients with severe pulmonary infections

Yuping Xu, Ruijuan Ren, Weiqing Liu, Ling Liu, Xinyan Cui, Jia Guo, Shujun Li

ABSTRACT To explore the diagnostic efficiency, clinical concordance, and precision treatment value of metagenomic next-generation sequencing (mNGS) for severe pulmonary infections in children in the pediatric intensive care unit (PICU), and to provide evidence for improving microbiological diagnosis and optimizing anti-infective strategies. A retrospective cohort study included 89 children with severe pneumonia in the PICU in 2024. All underwent routine microbiological testing and mNGS of bronchoalveolar lavage flu …

01.09.2026journal-article

Journal Human Research in Rehabilitation

Empathy and Ethics in Aesthetic Surgery: Between Medical Responsibility and Socially Constructed Beauty Ideals

Merima Kasumovic

Objective. To analyze the ethical, psychological, and social dimensions of contemporary aesthetic surgery, with particular emphasis on empathy in clinical decision-making, patient autonomy, body image disturbance, and the risks associated with unregulated practice. Narrative review. This manuscript is based on a qualitative narrative review of the literature in plastic surgery, bioethics, psychology, and public health, including professional guidance documents and selected epidemiological reports. Available evidenc …

01.09.2026journal-article

Journal Human Research in Rehabilitation

Exploring the Experiences of Novice Teachers in Kosovo in the Process of Entering the Teaching Profession

Selim Mehmeti, Arafat Shabani, Demush Bajrami

This qualitative descriptive case study explored the experiences of novice teachers at the beginning of their teaching careers in Kosovo, focusing on their professional support, adaptation to school culture, and teaching practice in real classroom settings. The study also examined the perceived contribution of pre-service teacher education programs and the institutional support needed during the first year of teaching. Data were collected through interviews with 15 novice teachers and an analysis of official docume …

01.09.2026journal-article

Journal Human Research in Rehabilitation

The Use of AI in Students’ Research Work: The Attitudes of Professors from Faculties of Education

Shqipe Avdiu-Kryeziu, Bahtije Gërbeshi Zylfiu

The purpose of this study is to gather the attitudes of professors from the Faculty of Education regarding their experiences with students’ use of artificial intelligence during research work. The study aims to identify the benefits, challenges, impacts on quality and academic integrity, ethics, privacy, perspectives, and the role of AI in the future of higher education. The research was conducted using a qualitative approach; the sample for this study is purposive, comprising a total of 20 university professors fr …

01.09.2026journal-article

Stroke

Ischemic Postconditioning in Patients With Acute Stroke With Successful Recanalization After Endovascular Therapy: A Pilot Randomized Controlled Trial

Yongbo Xu, Bohao Zhang, Shuling Liu, Xiao Jiang, Chen Cao, Qin Wang, Zhihong Xu, Shuai Liu, Kangjie Du, Sifei Wang, Leilei Luo, Xinran Qin, Marc Fisher, Xiaoguang Tong, Xunming Ji, Ming Wei

BACKGROUND: Ischemia-reperfusion injury contributes to continued infarct growth despite successful recanalization. Ischemic postconditioning (IPostC) reduces infarct size in preclinical models, but its therapeutic effect as an adjunct to endovascular thrombectomy remains uncertain. We investigated whether IPostC performed after successful recanalization reduces infarct growth in patients with acute ischemic stroke. METHODS: This single-center, prospective, randomized, open-label trial with blinded end point assessm …

01.09.2026journal-article

International Journal of Sports Physical Therapy

Adductor-Related Athletic Groin Pain: A Clinical Commentary

Derrick Larkins, Robert Rowland, Michael Zarro, Odessa Addison

Adductor-related athletic groin pain (ARAGP) is a common condition in athletes participating in multidirectional, high-intensity sports. It is challenging to diagnose and manage due to complex regional anatomy and overlapping clinical presentations. ARAGP represents the most frequently reported subtype of athletic groin pain and contributes substantially to time loss from play and performance limitation. This clinical commentary synthesizes current evidence related to the anatomy, risk factors, pathomechanics, imag …

01.09.2026journal-article

International Journal of Sports Physical Therapy

Acute Effects of Contract–Relax PNF With and Without Neuromuscular Electrical Stimulation on Hamstring Flexibility and Jump Performance in Adolescent Soccer Players: A Randomized Controlled Trial

Carlos Salvador-Huerta, Pedro Azanon-Nogueira, Eloi Suárez-Pazos, Valeria Betancourt-Cabeza, Irene Lazcano-Nogueira, Andrea Porcu, Ángel Manuel de la Hera-Sastre, Juan J. Amer-Cuenca, Juan Francisco Lisón

Background The additional value of neuromuscular electrical stimulation (NMES) during contract–relax proprioceptive neuromuscular facilitation (PNF-CR) stretching remains unclear, particularly in adolescent athletes. It is also unknown whether combining PNF-CR with motor-threshold NMES improves hamstring flexibility more than a sensory-threshold comparator without impairing vertical jump performance. Purpose To compare the acute effects of PNF-CR combined with motor-threshold NMES versus sensory-threshold NMES on h …

01.09.2026journal-article

American Journal of Critical Care

Effect of a Machine Learning Algorithm to Guide Goal-Directed Therapy After Cardiac Surgery

Amanda Rea, Alexandra Deasel, Clifford Edwin Fonner, Rawn Salenger

Background Goal-directed therapy allows clinicians to optimize perfusion and volume status in patients postoperatively. Objective To evaluate the effect of a machine learning algorithm to guide postoperative goal-directed fluid therapy in cardiac surgery patients. Methods A goal-directed fluid therapy program was implemented in a single center for coronary artery bypass patients with ejection fraction greater than or equal to 45% (implementation period: May 15, 2023, to May 31, 2024). Patient outcomes were compared …

01.09.2026journal-article

EDUCATOR : Jurnal Inovasi Tenaga Pendidik dan Kependidikan

PENGARUH KONSELING RATIONAL EMOTIVE BEHAVIOR THERAPY (REBT) TERHADAP KONTROL DIRI SISWA KELAS XI DI SMA NEGERI 1 GERUNG

Nanda Salsabilla Syaqinah, Hariadi Ahmad, M. Najamuddin

ABSTRACT Self-control is an individual's ability to regulate thoughts, emotions, and behaviors in accordance with goals and applicable norms, which plays an important role in students' academic success and social adjustment. This study was motivated by the identification of several eleventh-grade students at SMA Negeri 1 Gerung who demonstrated low self-control, as indicated by frequent lateness to class, becoming easily angry when reprimanded, noncompliance with school rules, and conflicts with peers. This study a …

01.09.2026journal-article

JMIR Cardio

Co-Creation and Usability Testing of a Digital Cardiac Rehabilitation Program (eCardiacRehab): Design and Development Study

Oda Karin Nordfonn, Kristin Johnsen Ramstad, Trond Roed Pettersen, Nina Hjertvikrem, Inger-Lise Aamot Aksetøy, Alf Johannes Agcaoili Borge, Eva Gerdts, Jan Gunnar Hesthammer, Torstein Hole, Irene Instenes, Anita Isaksen, Ole Andreas Krumsvik, Merethe Landaas, Christian Moltu, Svein Rotevatn, Jan Schjøtt, Cathrine Horn Sommersten, Jan Ove Tryti, Tone Merete Norekvål

Abstract Background Cardiac rehabilitation (CR) is a class IA–recommended treatment and secondary preventive strategy for people with coronary artery disease. eHealth solutions show promise in providing accessible CR. However, few provide a comprehensive and multimodal CR program, and most programs are developed without input from end users. Objective The aim of this study was to provide a detailed description of the multidisciplinary co-creation process used to develop a person-centered, multimodal digital CR prog …

01.09.2026journal-article

JIHAD : Jurnal Ilmu Hukum dan Administrasi

Criminalization of Hate Speech in Indonesian Positive Law: A Proportionality Analysis of Restrictions on Freedom of Expression

Alfred Ariyanto, Aryono Aryono, Muhammad Habib

The rapid development of information and communication technology has expanded freedom of expression while simultaneously increasing the dissemination of hate speech through digital media. This phenomenon has prompted the state to criminalize hate speech in order to protect public order, human dignity, and the rights of vulnerable groups. However, the regulation of hate speech in Indonesian positive law continues to raise concerns regarding legal certainty and the risk of excessive restrictions on freedom of expres …

03.09.2026journal-article

Pediatric Pulmonology

CFTR Modulator Therapy and Aerobic Fitness Changes in Aerobic Fitness Following Initiation of CFTR Modulator Therapy: A Systematic Review and Meta‐Analysis

Ingrid Silveira de Almeida, Fernanda Maria Vendrusculo, Mariana Severo da Costa, Márcio Vinícius Fagundes Donadio

ABSTRACT Introduction Cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy has led to relevant clinical advances in people with cystic fibrosis (pwCF). However, its effects on aerobic fitness are unclear. Objective To evaluate the effects of CFTR modulator therapy on aerobic fitness in pwCF through a systematic review and meta‐analysis. Methods This systematic review (CRD420251066602) was conducted by searching major databases without date or language restrictions. Analytical studies evaluat …

01.09.2026journal-article

International Journal of Public Health Science (IJPHS)

Association between occupational NO₂ exposure and hypertension risk: a PRISMA-based systematic review with risk-of-bias assessment

Ayudhia Rachmawati, Morrin Choirunnisa Thohira, Muhammad Aidil Fitrah, Vivi Filia Elvira

Nitrogen dioxide (NO₂) is a major air pollutant generated from fossil fuel combustion in transportation and industrial activities and is associated with adverse health effects. Prolonged exposure to NO₂ may induce chronic inflammation and endothelial dysfunction, which contribute to the development of hypertension. This study aimed to systematically review the association between NO₂ exposure and the incidence of hypertension among workers. The review was conducted in accordance with PRISMA guidelines, with literat …

01.09.2026journal-article

Current Oncology

Post-Treatment Trajectories of Retained Totally Implantable Venous Access Ports After Anticancer Therapy: A Conditional Landmark Cohort Study

Zeyang Fan, Tiantian Li, Kai Yang

Background: Retained totally implantable venous access ports (TIVAPs) pose a clinical management challenge after completion of intravenous anticancer therapy, particularly when future treatment needs remain uncertain. We aimed to characterize longitudinal post-treatment TIVAP trajectories after a day-90 conditional landmark, with elective removal prespecified as the primary first event. Methods: This retrospective cohort study included patients who were alive and event-free, retained the original TIVAP, had no docu …

01.09.2026journal-article

Journal Human Research in Rehabilitation

Technology and Inclusive Education: Opportunities and Challenges for Students with Special Educational Needs

Vjosa Thaqi, Luljeta Shala, Biljana Cvetkova Dimov, Daniela Andonovska Trajkovska

This study investigates the role of technology in supporting inclusive education for students with special needs in lower secondary schools in Kosovo. Using a mixed-methods approach, data were collected through interviews with 26 students (15 from regular classes and 9 with special needs) and 9 parents. The findings show that technology enhances motivation, independent learning, collaboration, and active participation. Students reported frequently using tablets, computers, interactive applications, and multimedia r …

01.09.2026journal-article

Journal of Instrumentation

A novel rotating gantry for heavy-ion therapy

Y.J. Zheng, J.C. Yang, Y.X. Pang, L.N. Sheng, Y.B. Lang, H.J. Lu, G. Wang, S. Ruan, L. Zhang, P.F. Liu, X.D. Zhang, Y.P. Wan, Y.B. Zhang, X.W. Xu, Y.Q. Yang, Z.E. Yao

Abstract Heavy-ion therapy is a widely utilized technology for cancer treatment worldwide. Conventional treatment facilities typically adopt either fixed beamlines or rotating gantries to enable multi-angle irradiation. In order to realize different irradiation angles, the fixed beamlines are designed to be quite long, resulting in a large footprint and high costs. Traditional rotating gantry has been commonly used in proton therapy and have proven highly effective. However, there are significant challenges for app …