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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Frontiers in Organizational Psychology

The factors associated with workforce attrition and intention-to-leave among healthcare workers in New Zealand: a systematic literature review and meta-synthesis of qualitative research

Mia Clarke, Ben Stephen, Mike Frecklington, Irene Zeng, Matthew R Carroll, Richard J Siegert, Sarah Stewart

Despite growing concern about the stability of New Zealand's (NZ) health workforce, no prior synthesis has examined qualitative evidence on factors associated with attrition or intention-to-leave. This systematic review and meta-synthesis included 20 studies and followed the ENTREQ checklist to guide a content analysis of the literature. Seven themes were generated spanning organizational, professional, and personal levels: high workloads, unsupportive organizational culture, limited opportunities for career advanc …

03.09.2026journal-article

Frontiers in Health Services

Patient misidentification and data integrity risks in ultrasound imaging: a case report using multi-framework incident analysis

Benedicta Osei-Donkor, Abdallah Hassoun, Md Shafiqur Rahman Jabin

Background Digital imaging workflows depend on accurate scheduling, patient identity reconciliation, and reliable metadata continuity to ensure safe image storage and retrieval. Disruptions in these processes may not directly affect image acquisition but can delay access to imaging information and pose significant patient safety risks. Objective To examine a recurrent ultrasound workflow failure that compromised downstream image availability and to identify practical strategies for preventing recurrence. Methods A …

03.09.2026journal-article

Frontiers in Medicine

Global trends and thematic clusters in healthcare professional education, medical errors, and patient safety: a bibliometric analysis, 2000–2026

Birgit Hladschik-Kermer, Olena Litvinova, Michel-Edwar Mickael, Maima Matin, Ahmed Fatimi, Anass Belbachir, Mairim Russo Serafini, Maria Kletecka-Pulker, Atanas G. Atanasov, Thomas Wochele-Thoma

Background In the context of the active implementation of the World Health Organization’s Global Patient Safety Action Plan, there is a growing need for a comprehensive synthesis of scientific evidence reflecting the development of research in the field of healthcare professional education. Objective This study aims to conduct a bibliometric analysis of scientific publications addressing the relationship between healthcare professional education, medical errors, and patient safety over the period 2000–2026, based o …

03.09.2026journal-article

Journal of Clinical Medicine

The Impact of Glucagon-like Peptide-1 (GLP-1) Receptor Agonists on Body Composition in Individuals with Overweight and Obesity: A Systematic Review and Meta-Analysis

Miłosz Woźniak, Zofia Tarcz, Gabriela Pyczek, Julia Bogacka, Andrzej Diniejko, Alina Kuryłowicz, Artur Mamcarz, Daniel Śliż

Background/Objectives: Excess adipose tissue is associated with adverse changes in muscle metabolism and body composition. GLP-1 receptor agonists (GLP-1 RA) have transformed the treatment of obesity; however, concerns remain regarding the potential impact of treatment-associated weight loss on lean mass. This study aimed to evaluate the effects of GLP-1 RA on body composition in adults with obesity without type II diabetes mellitus (T2DM), with a particular focus on changes in lean mass. Methods: A database search …

03.09.2026journal-article

Healthcare

Association of Aspirin Use with In-Hospital Mortality in Patients with Radiation-Associated Acute Pneumonitis: Insights from the National Inpatient Sample Database

Akash Sharma, Shalini, Sowntappan Balasubramanian, Hamza Yousaf, Ankit Agrawal, Vrinda Vyas

Introduction: This study investigates the relationship between long-term aspirin use and mortality in patients experiencing acute radiation-induced pulmonary complications. Methods: We conducted a secondary analysis from the National Inpatient Sample from 2016 to 2020. Our cohort comprised patients diagnosed with acute pneumonitis secondary to chest radiation. We adhered strictly to the STROBE checklist, extracting various patient characteristics for analysis. Categorical variables were compared using Pearson’s chi …

03.09.2026journal-article

International Journal of Computer Science and Mathematical Theory

Mathematical Modelling of Epidemiological Infectious Disease Transmission Dynamics: Public Health Intervention Strategies

Christiana Nkuturum

This study explores the epidemiological infectious disease transmission dynamics with public health intervention strategies using nonlinear ordinary differential equations with four compartments in a mathematical modeling approach. The study identified two major public intervention strategies as preventive and treatment measures. The findings of this study are that the region D of the subset is a positively-invariant set mathematically and epidemiologically from the model equation (1) as a result of the two interve …

03.09.2026journal-article

Current Issues in Molecular Biology

Dynamic Changes in PD-L1, VEGF, and TILs Following Neoadjuvant Therapy in Residual Invasive Breast Cancer

Marina Bakula, Jasmina Rajc, Ana Kvolik Pavic, Slavica Kvolik

Background/Objectives: Neoadjuvant therapy (NAT) may remodel the breast-cancer microenvironment. We evaluated paired changes in programmed death-ligand 1 (PD-L1), vascular endothelial growth factor (VEGF), and tumor-infiltrating lymphocytes (TILs) before and after NAT, and associations with the residual cancer burden (RCB) and survival. Methods: This retrospective study included 102 patients with residual invasive breast cancer after NAT: 34 with luminal B-like/HER2-negative, 34 with luminal B-like/HER2-positive, a …

03.09.2026journal-article

Journal of Medical Clinical Case Reports

Digital Distrust: Patient-Centred Communication and the Calibration of Epistemic Reliance in the Era of Online Self-Diagnosis and AI Symptom Checkers

Nonye Tochi Aghanya, Osinakachi Akuma Kalu

Background: Patients are coming to consultations informed by search engines, social media and generative AI. Clinicians may characterize this as distrust of clinicians. Actualities are messier, and our language for talking about how communication breaks down is limited. Purpose: Operationalize the concept of digital distrust, disambiguate it from related concepts with which it is often confused, and report a communication framework grounded in theory for clinical practice. Methods: Methodology is an interpretive co …

03.09.2026journal-article

Frontiers in Dental Medicine

Curcumin as an adjunct in periodontal therapy: local effects, delivery systems, and clinical perspectives

Ana Carolina Aparecida Rivas, Mario Taba, Paola Gomes Souza

Curcumin, the active polyphenol in turmeric (Curcuma longa), is well-known for its anti-inflammatory, antioxidant, and antimicrobial properties, making it a promising therapeutic agent for a range of diseases, including neuroinflammatory conditions and periodontal disease. Periodontitis, a prevalent oral disease, is associated with chronic inflammation and bacterial infection. Curcumin has demonstrated antibacterial effects against periodontal pathogens such as Aggregatibacter actinomycetemcomitans, Porphyromonas g …

03.09.2026journal-article

Frontiers in Medicine

Time-Series modeling for predicting mortality risk in intensive care unit patients with pulmonary inflammation

Yihai Zhai, Ruixin Xu, Haisu Lu, Siying Lv, Liqin Mo

Objective This study aims to evaluate dynamic changes in pneumonia-related mortality risk among ICU patients using time-series models and develop interpretable predictive models for early mortality assessment. Methods Data were obtained from the MIMIC-IV and eICU Collaborative Research Database. The MIMIC-IV cohort was split into training and testing sets (7:3 ratio), with external validation conducted using the eICU cohort. Missing data were handled using forward filling and multiple imputation. LSTM was used to e …

03.09.2026journal-article

Frontiers in Medicine

Design, implementation, and evaluation of a programmatic assessment model in an emergency medicine residency: a mixed-methods study

İbrahim Ulaş Özturan, Dilek Kitapcioglu, Prattama Santoso Utomo, Cansu Alyesil Ozturan, Nurettin Özgür Doğan, Elif Yaka, Serkan Yılmaz, Murat Pekdemir, Levent Altıntaş

Background Programmatic assessment (PA) is widely endorsed in postgraduate medical education, but empirical accounts of real-world implementation in emergency medicine (EM) remain limited and are concentrated in North American settings. We piloted and evaluated the design, implementation, and outcomes of a PA model in an EM residency at a high-volume tertiary care center in Türkiye. Methods A mixed-methods study was conducted over an eight-month pilot (November 2024–June 2025). Program design and evaluation followe …

03.09.2026journal-article

Frontiers in Oncology

Analysis of clinical features and outcomes in a Chinese cohort with ALK fusion across pan-cancer: a retrospective study

Meng Zhang, Yi Feng, Xue Du, Changda Qu, Meizhu Meng, Meiying Ye, Min Liang, Ziran Yang, Wenjuan Gong, Xingyu Ma, Jialiang Guo, Wenmei Li, Shuqin Jia

Background ALK fusions are validated oncogenic drivers, yet their molecular heterogeneity and therapeutic implications remain poorly characterized. This study defined the landscape of ALK fusion partners, EML4-ALK variants, and co-mutations and their impact on treatment responses in a large Chinese pan-cancer cohort. Methods We retrospectively analyzed 16,335 consecutive pan-cancer patients via next-generation sequencing to identify ALK fusions. Clinical characteristics, fusion partners, co-mutations, and treatment …

03.09.2026journal-article

Indoor and Built Environment

Causes of PM 2.5 pollution in the atmospheric environment, health risks and economic losses in different geographical administrative regions

Yongbo Cui, Huihui He, Xiaoqing Zhou, Chengliang Fan

PM 2.5 has become a major pollutant in the atmospheric environment, posing a serious threat to people's health and seriously hindering the sustainable development of urban environments. However, there is still limited assessment of the health risks and economic losses associated with PM 2.5 pollution in megacities. Therefore, this study systematically analysed the spatiotemporal distribution characteristics, health risks and economic losses associated with PM 2.5 concentrations in seven typical Chinese cities. The …

03.09.2026journal-article

Nutrition and Health

Potential effects of kombucha on endoplasmic reticulum stress and weight regulation in a high-fat diet-induced obesity model

Didem Korkmaz, Ayşe Gül Mutlu

Background Obesity is increasingly recognized as a global metabolic disease, often accompanied by endoplasmic reticulum (ER) stress, which contributes to the development of metabolic disorders such as insulin resistance and type 2 diabetes. Kombucha, a fermented tea known for its health-promoting effects, has been associated with weight loss and lipid-lowering properties. Aim This study aimed to evaluate the potential effects of kombucha on ER stress in obese rats induced by a high-fat diet (HFD). Methods Fifty mal …

03.09.2026journal-article

Borneo Nursing Journal (BNJ)

Hubungan Tingkat Sosial Ekonomi Dengan Kejadian Food Neophobia Pada Anak Pra Sekolah Usia 3-6 Tahun

Eka Ageng Febriyanti, Khoirun Nisa Alfitri, Ibtidau Niamilah

Food neophobia adalah perilaku makan yang umum di antara anak-anak prasekolah dan dapat mengurangi keragaman pola makan serta kecukupan nutrisi. Status sosial ekonomi orang tua dianggap sebagai salah satu faktor yang memengaruhi perilaku makan anak. Studi ini bertujuan untuk menentukan hubungan antara status sosial ekonomi orang tua dan food neophobia pangan pada anak prasekolah usia 3-6 tahun di wilayah kerja Puskesmas Gamping 1, Kabupaten Sleman. Studi kuantitatif ini menggunakan desain analitik observasional den …

03.09.2026journal-article

Borneo Nursing Journal (BNJ)

Thought Stopping Dan Terapi Musik Klasik Terhadap Gangguan Persepsi Sensori: Halusinasi Pendengaran Pada Ny.S Dengan Skizofrenia Di Rumah Sakit Marzoeki Mahdi

Elisa Maulida Rahmawati, Tressia Febrianti

Skizofrenia merupakan gangguan jiwa kronis yang sering disertai halusinasi pendengaran sehingga memengaruhi kemampuan individu dalam membedakan realitas, mengendalikan perilaku, dan berfungsi secara sosial. Penerapan evidence-based nursing melalui kombinasi Thought Stopping dan terapi musik klasik dilakukan pada pasien skizofrenia dengan gangguan persepsi sensori: halusinasi pendengaran di Ruang Srikandi Rumah Sakit Marzoeki Mahdi menggunakan metode studi kasus dengan pendekatan proses keperawatan. Intervensi diber …

03.09.2026journal-article

Borneo Nursing Journal (BNJ)

Hubungan Self-Care Management Dengan Kualitas Hidup Pasien Hemodialisis

Dentha Aditiya, Agung Widiastuti, Musta'in

Background: A patient's quality of life remains significantly influenced by their ability to perform self-care management, although hemodialysis therapy can help maintain their function. This self-care management includes adherence to fluid restrictions, dietary adjustments, taking medications as prescribed, and undergoing regular hemodialysis.Objective: This study aimed to determine the relationship between self-care management ability and the quality of life of patients undergoing hemodialysis. Methods: This quan …

03.09.2026journal-article

Journal of Universal Science Research

THE IMPACT OF PRE-MARITAL MEDICAL EXAMINATION ON YOUTH REPRODUCTIVE HEALTH

Mahmudova E’zoza

The article analyzes the essence, purpose, and practice of the pre-marital (preconception) medical examination system established by law in the Republic of Uzbekistan. The role of pre-marital medical screening in preventing hereditary and congenital diseases, as well as in assessing the reproductive health of prospective spouses, is examined. At the same time, the strengths and weaknesses of the existing system, the attitude of young people toward this process, and proposals for its improvement are presented

03.09.2026journal-article

Buildings

Restorative Experiences Associated with Built Heritage Settings: The Role of Cognitive and Emotional Pathways in Public Mental Well-Being

Kai Zhu, Hui Tang

Built heritage environments are increasingly recognized as important components of the built environment that shape human experiences beyond their cultural and historical values. However, how heritage-related experiences are associated with restorative perceptions through cultural interpretations and human–place relationships remains insufficiently understood. This study examines the mechanisms underlying perceived restorativeness in built heritage environments by integrating heritage identity and place attachment. …

03.09.2026journal-article

Clinical Chemistry and Laboratory Medicine (CCLM)

Translating analytical performance into clinical misclassification risk: a probabilistic framework for HbA 1c interpretation

Lorenza Fagnani, Rita Tennina, Pierangelo Bellio, Patrizia Frascaria, Marco Rossi, Sabrina Viggioni, Moira Tucceri Cimini, Consuelo Scimia, Alessandra Piccirilli, Mariagrazia Perilli, Fabio Antonelli, Giuseppe Celenza

Abstract Objectives Using HbA 1c for diabetes diagnosis directly links analytical uncertainty to patient classification. Since traditional performance metrics provide limited insight into these clinical implications, we developed a probabilistic framework to translate HbA 1c concentrations and components of analytical uncertainty into clinically interpretable diagnostic risk. Methods The framework was applied to 100,472 HbA 1c results obtained from a real-world Laboratory Information System. Analytical bias, analyt …

03.09.2026journal-article

Sage Sphere International Journal

Cirugía laparoscópica versus cirugía robótica en la resección de tumores hepáticos: resultados y beneficios clínicos

Joel Sebastian Chango Yosa, Kelvin Alejandro Torres Quezada, Anthony Bryan Cevallos Falcones, Dana Isabel Morales Figueroa, Alonso Patricio Espinoza Ayala

Introducción: La resección hepática constituye el tratamiento principal de diversos tumores hepáticos. Los abordajes laparoscópico y robótico han ampliado las posibilidades de cirugía mínimamente invasiva, especialmente en procedimientos técnicamente complejos. Objetivo: Sintetizar la evidencia científica sobre los resultados y beneficios clínicos de la cirugía laparoscópica versus robótica en la resección de tumores hepáticos. Metodología: Se realizó una revisión bibliográfica narrativa mediante búsquedas en PubMe …

03.09.2026journal-article

Clinical Journal of the American Society of Nephrology

Predictive Value of Urine Tubular Biomarkers on Kidney Outcomes

Greco B. Malijan, William G. Herrington, Parminder K. Judge, Rebecca J. Sardell, Daniel Chapman, Michael Hill, Stewart Moffat, Doreen Zhu, Alfred K. Cheung, Dominik Steubl, Martin J. Landray, Christoph Wanner, Colin Baigent, Richard Haynes, Joachim H. Ix, Natalie Staplin, Michael G. Shlipak, on behalf of the EMPA-KIDNEY Collaborative Group

Background Urine tubular biomarkers have previously been associated with chronic kidney disease (CKD) progression independently of estimated glomerular filtration rate (eGFR) and albuminuria. We evaluated whether nine urine tubular biomarkers could improve prediction of kidney failure beyond serum creatinine and urine albumin-to-creatinine ratio among adults with CKD. Methods Among 5100 participants in EMPA-KIDNEY, a randomized trial which assessed the effects of empagliflozin 10 mg versus matching placebo among pa …

03.09.2026journal-article

Physical Therapy

Biomechanical Contributions to Alterations in Peak Metabolic Capacity and Efficiency Following Locomotor Training in Individuals After Stroke

T George Hornby, Abbey Plawecki, Jennifer K Lotter, Emily G Lucas, Devan Parrott, Christopher E Henderson

Abstract Importance Changes in peak metabolic capacity (Vo2peak) and gait efficiency at matched speeds (Vo2match) are often observed in individuals after stroke following locomotor training, although it is uncertain how those changes are achieved. Objective The objective of this study was to evaluate the effects of locomotor training on changes in Vo2peak and Vo2match in individuals after stroke and their associations with changes in locomotor kinematics and kinetics. Design This study was a secondary analysis of a …