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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Frontiers in Nutrition

The effects of maternal dietary fiber and short-chain fatty acids on the health of offspring: a mini review

Shaozhi Liu, Senling Feng, Zhongwen Yuan, Zhengrong Mei, Jinjin Yin, Lei Chen, Yongxia Zhang

Maternal nutrition during pregnancy is a critical determinant of offspring long-term health. Dietary fiber has emerged as a key modifiable factor. Through gut microbial fermentation, fiber is converted into short-chain fatty acids (SCFAs), primarily acetate, propionate, and butyrate. This mini review synthesizes current evidence from molecular, animal, and human studies on the role of maternal SCFAs in programming offspring metabolic and immune health. Mechanistically, SCFAs act via two complementary pathways: acti …

03.09.2026journal-article

Frontiers in Neuroscience

How physician relationships with neurotechnology companies impact clinical practice: interviews with physicians

Meredith V. Parsons, Judith M. Mwobobia, Erin D. Solomon, Michael Kudom-Agyemang, James M. DuBois, Tristan McIntosh

Introduction Physicians and neurotechnology companies each play a critical collaborative role when integrating neurotechnology into clinical practice. Physicians serve as gatekeepers and decision-makers in adopting neurotechnology, while companies often support the development, training, and maintenance of these devices. Relationships with industry require physicians to navigate complex clinical, ethical, and technological factors that affect their clinical roles. To understand physicians’ relationships with neurot …

03.09.2026journal-article

Frontiers in Medicine

Development and validation of an automatic machine learning-based myocardial contusion prediction model in rib fracture patients: a retrospective multicenter cohort study

Yan Yang, Ping Liu, Ni Jia, Yisha Xu, Peng Wu, Zhigang Zhang, Tingyong Han, Yan Jiang, Xianpeng Huang, Long Li

Objective This study aims to construct an automatic machine learning-based prediction model to accurately identify the risk of myocardial contusion in traumatic rib fracture patients, addressing the core limitations of insufficient sensitivity in traditional diagnostic methods and difficulties in clinical translation of existing prediction models. Methods A multicenter retrospective study design was adopted, including 1,038 rib fracture patients from 8 hospitals (training set: 808 cases; testing set: 230 cases) fro …

03.09.2026journal-article

Frontiers in Public Health

Declining trends but persistent disparities in cervical cancer mortality in the United States, 1999–2023

Jie Liu, Yonglin Liu, Yanjiao Jiang, Xuefeng Wang, Xianwei Zhou

Background Cervical cancer is largely preventable through effective screening and human papillomavirus (HPV) vaccination; however, mortality disparities remain a persistent public health challenge in the United States. This study aimed to examine long-term trends and socio-demographic and geographic inequalities in cervical cancer mortality. Methods We conducted a population-based study of cervical cancer mortality among U.S. women aged ≥25 years from 1999 to 2023 using national mortality data from the CDC WONDER d …

03.09.2026journal-article

Journal of Health Science and Medical Research

Successful Management of the Response to the COVID-19 Pandemic in the Bangkok Metropolitan Administration

Matanee Radabutr, Jureerat Kijsomporn, Payao Phongsakchat, Kanjana Anutariya

Objective: This research aimed to study the successful management of the response to the COVID-19 pandemic in the Bangkok Metropolitan Administration. Material and Methods: A mixed-methods convergent design was conducted. The qualitative component involved 30 semi-structured interviews with healthcare providers from three public health service centers in the Bangkok Metropolitan Administration, using seven open-ended questions until data saturation was reached. The quantitative sample, based on G*Power analysis, co …

03.09.2026journal-article

Journal of Anatolian Environmental and Animal Sciences

Clinical and Radiographic Evaluation of Stabilisation Using a Minimally Invasive Bridge Plate in Femur and Tibia Fractures in Dogs

Kamil Serdar İnal, Can Nacar, Elif Bağatır Kurban, Birsen Deniz Ersoy

Bridge plate fixation performed using a minimally invasive technique, the main fracture fragments are stabilised along the anatomical axis, rather than reducing small fragments, particularly in comminuted fractures. This retrospective study aims to evaluate the clinical and radiographic outcomes of stabilising traumatic femoral and tibial fractures in dogs using a minimally invasive bridge-plate technique. A total of 21 fractures (10 femoral and 11 tibial) from 20 dogs were included in the study. Cases were divided …

03.09.2026journal-article

Journal of Clinical Nursing

Staff Confidence and Barriers to Complex Clinical Communication in Nursing Homes: A Convergent Mixed‐Methods Study

Silvia Gonella, Eugenia Malinverni, Luciano Orsi, Filippo Laurenti, Stefania Chiodino, Monica Seminara, Simona Operto, Dario Cencio, Marina Sozzi, Giovanna Marsico, Francesca Paruzzo, Mariagrazia Imperato, Jacopo Olagnero, Maria Rivolta, Ilaria Lovetro, Luigi Stella, Valerio Dimonte, Sara Campagna

ABSTRACT Aim To describe all nursing home staff members' confidence in engaging in complex clinical communication with residents and family carers, and to explore factors affecting their attitudes. Methods A convergent mixed‐methods study used questionnaires ( n = 288) and 15 group‐based discussions involving 278 professionals across nine nursing homes between April and May 2025. Quantitative data were analysed descriptively, and qualitative data underwent inductive thematic analysis. Findings from the two strands …

03.09.2026journal-article

JMIR Formative Research

Real-World Impact of Remote Patient Management on Care Consumption and Care Time in Heart Failure: Retrospective Cohort Study

Wessel William Nieuwenhuys, Mayke Maria Christina Josephina van Leunen, Jeroen Albert Adrianus van de Pol, Frederique Jantine Hafkamp, Rudolph Ferdinand Spee, René Anton Tio, Mathias Funk, Hareld Marijn Clemens Kemps

Abstract Background Remote patient management (RPM) is a strategy to track daily health data in patients with heart failure (HF) to enable early detection and treatment of decompensation to prevent hospital readmissions. The implementation of RPM alters standard care and redistributes provider responsibilities. Although randomized controlled trials demonstrate positive clinical outcomes, the impact of implementing RPM on patients’ health care usage, as well as the care time and workload of health care providers in …

03.09.2026journal-article

Regenerative Biomaterials

pH-responsive hydrogel facilitates skin penetration of extracellular vesicle-like nanovesicles for enhanced atopic dermatitis therapy

Kaizheng Li, Mengnan Dai, Chao Xu, Zengjie Fan

Abstract Atopic dermatitis (AD) is a chronic inflammatory skin disorder, and the long-term use of topical corticosteroids is often limited by adverse effects and poor tolerability. Herein, we developed CAAM-G, a corticosteroid-free hydrogel platform composed of carboxymethyl cellulose, acrylamide, and acrylic acid and loaded with Gentiana macrophylla Pall.-derived extracellular vesicle-like nanovesicles (GELNs) and L-menthol. The hydrogel exhibited favorable mechanical properties, tissue adhesion, and swelling capa …

03.09.2026journal-article

Frontiers in Psychiatry

Motivational and emotional determinants of health goal progress in inflammatory bowel disease: a longitudinal study

Barbara Horvát, Anett Dávid, Viola Sallay, Beatrix Rafael, Sanela Njers, Kata Orbán, Tamás Molnár, Márta Csabai, Ádám Tóth, Tamás Martos

Background Self-management among patients with inflammatory bowel disease (IBD) is influenced by motivational and emotional factors. Although research has increasingly highlighted psychological support, it has underexplored interactions among goal-related emotions, motivation types, and progress in health-related behavior. Methods A total of 123 adults diagnosed with IBD participated in a longitudinal study, completing questionnaires at baseline (T1) and at follow-ups after three months (T2) and six months (T3). Me …

03.09.2026journal-article

Frontiers in Rehabilitation Sciences

Transfer effects of animal-assisted therapy on socioemotional skills in adult inpatient rehabilitation after acquired brain injury: a randomized controlled trial

Elena Pauli, Sophie Dubach, Carmina Haase, Anna Haefeli, Margret Hund-Georgiadis, Jan Hattendorf, Karin Hediger

Background People with acquired brain injury (ABI) often experience difficulties in social and emotional functioning, potentially affecting recovery and quality of life. Animal-assisted therapy (AAT) is increasingly used in rehabilitation to support socioemotional functioning. Objective This randomized controlled trial investigated whether the effects of AAT extend beyond therapy sessions in patients with ABI undergoing inpatient neurorehabilitation. We hypothesized that patients receiving AAT would demonstrate gre …

03.09.2026journal-article

Frontiers in Psychology

Academic self-perceptions and AI use among health professions students: the serial mediating roles of learned helplessness and academic-clinical learning loneliness

Pinar Ayyildiz

Objective This study inspected the direct and indirect relationships between academic self-perceptions and artificial intelligence (AI) use among health professions students. More specifically, it investigated if learned helplessness and academic and clinical learning loneliness independently and sequentially mediated the relationships of academic wellbeing, academic incompetence, impostor syndrome and overall academic self-perceptions with AI use. Methods A quantitative, cross-sectional, and correlational design w …

03.09.2026journal-article

PLOS Digital Health

Community-based malaria surveillance in Cambodia using a mobile reporting app for village malaria workers: An implementation case study

Pengby Ngor, Huy Rekol, Siv Sovannaroth, Po Ly, Eng Thyda, Sok Kimleng, Yoem Rattana, Ou Vunsokserey, Hem Vanna, Ran Sany, Chang Pumeoung, Steven Mellor, Rady Try, Pascal Ringwald, Richard J. Maude, Lisa J. White

To support malaria elimination, Cambodia implemented a locally developed, nationally integrated, community-based mobile digital surveillance system enabling real-time, case-based detection, reporting and response. This implementation case study describes the development, national deployment and operational performance of an Android-based mobile app used by Village Malaria Workers (VMWs) and Mobile Malaria Workers (MMWs) integrated within the national Malaria Information System (MIS). Developed collaboratively with …

03.09.2026journal-article

Journal of Clinical Medicine

Detection-Guided ROI-Constrained Diffusion for Weakly Supervised White Blood Cell Segmentation: A Retrospective Internal and External Dataset Evaluation

Julius Bamwenda, Mehmet Siraç Özerdem, Orhan Ayyildiz, Veysi Akpolat, İrem Akpolat

Background: Accurate white blood cell (WBC) segmentation is important for quantitative microscopic image analysis, but conventional supervised approaches depend on labor-intensive pixel-level annotations and may exhibit reduced robustness across datasets. This study proposes a detector-guided, region of interest (ROI)-constrained framework that combines automatic localization, pseudo-mask-based weak supervision, and diffusion-assisted segmentation. Methods: You Only Look Once version 13 Nano (YOLOv13-N) was used to …

03.09.2026journal-article

PLOS One

Physiological and psychological outcomes of a community-based Kurort Health Walking program: A before–after study

Saori Miura, Shinji Horikawa, Kana Morizono, Miyu Miyazaki, Hiroki Torii, Hiromi Kuroda, Emi Matsuura

Objective This study aimed to evaluate short-term physiological and psychological changes associated with participation in a community-based Kurort Health Walking program conducted in a forest environment. Patients and methods This study was conducted as part of a public health program in Saikai City, Nagasaki, Japan. A total of 90 participants who attended certified Kurort Health Walking courses between March 2024 and March 2025 were included. Physiological parameters, including systolic and diastolic blood pressu …

03.09.2026journal-article

Journal of Clinical Medicine

Clinical Comparison of 4D Phaco and Torsional Ultrasound Phacoemulsification Platforms: Association with Cumulative Dissipated Energy and Postoperative Inflammatory Response

Hisaharu Suzuki

Background/Objectives: Four-dimensional Phaco and torsional ultrasound represent distinct approaches to phacoemulsification, and both platforms are compatible with a hybrid polymer-coated tip designed to reduce posterior capsule contact risk. Clinical comparative data evaluating both ultrasound efficiency and postoperative inflammatory response remain limited. Methods: We retrospectively compared 149 eyes of 139 patients undergoing phacoemulsification with the UNITY (4D Phaco) or CENTURION (torsional ultrasound) pl …

03.09.2026journal-article

Healthcare

Willingness to Share Smartwatch-Generated Health Data Among a Sample of Adults in Riyadh, Saudi Arabia

Raniah N. Aldekhyyel, Leena M. Shagrani, Shoug M. Albattah, Basmah A. Alghamdi, Adwaa A. Alsalman, Shadin K. Alabbas, Haya E. Alkhlaiwi

Background/Objectives: Wearable devices, such as smartwatches, represent an emerging digital health tool that can enhance patient engagement, support patient-provider communication, and enable more personalized, patient-centered care. Understanding public willingness to share health-generated data with healthcare providers is essential for informing digital health implementation strategies that prioritize patient trust and active participation in the care process. This study aimed to address this gap by assessing t …

03.09.2026journal-article

JAMA Oncology

Neoadjuvant Anbenitamab and HB1801 in ERBB2 -Positive Breast Cancer

Junjie Li, Tong Liu, Ke-Da Yu, Huawei Yang, Zhen Huang, Yi Zeng, Peng Ji, Xiaoke Hou, Chunping Liu, Yiwen Zhang, Nanlin Li, Zhong Ouyang, Xiaobo Wu, Xiaorong Bai, Yanxiang Guo, Guohui Han, Shien Cui, Zhijun Zhu, Yu Zhang, Xiaobo Hu, Xiaopeng Ma, Peifen Fu, Jinhai Zhu, Yuan Dong, Tao Wu, Hongyan Jia, Fei Xu, Yu Ren, Jianyun Nie, Dai Bing, Qiang Mu, Tao Sun, Jing Luo, Zhenchuan Song, Xiangshun Kong, Hao Zhang, Zhiyong Wu, Zhihong Wang, Dong Song, Haiquan Jia

IMPORTANCE The combination of neoadjuvant taxanes with trastuzumab and pertuzumab remains the cornerstone treatment strategy in ERBB2 -positive breast cancer. Anbenitamab (a ERBB2 -biparatopic antibody that induces profound receptor clustering) and HB1801 (a solvent-free albumin-bound docetaxel), have shown promising antitumor activity and an acceptable safety profile in patients with breast cancer. OBJECTIVE To evaluate whether neoadjuvant anbenitamab combined with HB1801 could improve efficacy without increasing …

03.09.2026journal-article

BMC Public Health

Awareness level of cancer risk factors and warning signs among adults in Mansoura District, Egypt

Ahmed M. Eid, Abeer M. Kamal, Asmaa Elsayed, Rahma M. Almetwaly, Basma Kamel, Naira A. Shoman, Aya M. Abdelmohsin, Sara H. Elhendawy, Yasmeen A. State, C. A. collaboration team, Abdallah Gamal, Menna S. Sellow, Nourhan R. Elbatal, Mohamed A. Abdelaziz, Ahmad M. Gewili, Mariam B. Elbialy, Nouran K. Mashaly, Rania S. Omar, Abdelrahman M. Darweesh, Abdelsmad Elhalwaty, Hager S. Elhebeshy, Moustafa Y. Nassar, Hanin Fadl, Ahmed H. Maarouf, Omar M. Eid, Sama Mahmoud Abo Younis, Ashraf Alaziz, Mokhtar M. Elkerdawey, Ahmed Mohamed Zayed, Abdel-Hady El-Gilany

Abstract Background Cancer remains a leading cause of mortality worldwide, with prevention and early detection dependent on the public awareness of its risk factors and warning signs. However, knowledge of cancer-related symptoms and modifiable risk factors remains limited in many populations, particularly in low- and middle-income countries. Limited research exists examining general cancer awareness in Egypt's general population. Objective To assess public knowledge of cancer's early warning signs, risk factors, a …

03.09.2026journal-article

Journal of Intensive Care Medicine

Inferior Vena Cava Filters: Relevant Issues for Hospitalists and Intensivists

Joshua Valbuena, Eric vanSonnenberg, T. Gregory Walker

Inferior Vena Cava (IVC) filters are medical devices that are inserted into the IVC as a form of mechanical prophylaxis against pulmonary emboli (PE). Placement of IVC filters is controversial, as IVC filters can lead to complications, especially when left implanted for longer than the recommended time. In this review, IVC filter complications are divided into several categories: acute, long-term, and those associated with filter removal. Life-threatening complications of IVC filter use also are examined. Key facto …

03.09.2026journal-article

Borneo Nursing Journal (BNJ)

Hubungan Durasi Puasa Terhadap Kejadian Mual Muntah (PONV) Pada Pasien Elektif Post Operasi Dengan Anestesi Umum

Devi Ayu Putri Aryandani, Supono, Kissa Bahari, Tri Nataliswati

Puasa praoperasi merupakan prosedur standar untuk mencegah aspirasi selama anestesi umum. Namun, durasi puasa yang terlalu panjang dapat menimbulkan ketidaknyamanan dan meningkatkan risiko komplikasi pascaoperasi, salah satunya Postoperative Nausea and Vomiting (PONV). Penelitian ini dilakukan untuk mengetahui hubungan antara durasi puasa dengan kejadian PONV pada pasien elektif yang menjalani anestesi umum di RSI Aisyiyah Malang. Penelitian menggunakan desain analitik observasional dengan pendekatan cross-sectiona …

03.09.2026journal-article

Peace Economics, Peace Science and Public Policy

Introducing the Tactics and Resources Dataset: Resources, Sponsors and Escalation of Non-state Actors

Tom Konzack

Abstract To cut through inconsistent findings on non-state violence born of contested concepts and uneven data, I introduce the Tactics and Resources Dataset (TRD): a panel dataset on 649 violent and non-violent political non-state organisations. It focuses on their tactical choices and the types and origins of resources provided to them, alongside political, social, and economic indicators and key historical junctures. TRD offers a robust empirical foundation for studying how various types of resources and externa …

03.09.2026journal-article

Clinical Infectious Diseases

A Multistate Investigation of Serious Adverse Events, including Deaths, following Ceftriaxone Injections, September 2024–August 2025

Rebecca Pierce, Radhika Agarwal, Dumbani Kayira, Maribeth C Lovegrove, Nimalie D Stone, Kelly M Hatfield, Jennifer Lind Lyles, Melissa Morrison, Wes Stubblefield, Sherri L Davidson, Karen Landers, Scott Harris, Rachana Bhattarai, Theresa Dulski, Juliet Stoltey, Lauren Biehle, Josh Hoffner, Argentina Charles, JoAnna Wagner, Haley Beeman, Michael J Curran, Grace Lee, Riley Moore, Jacy Walters, Gargi Patel, Dat Tran, Jenna Sinkevitch, Marco Tori, Christopher Wilson, Simone Godwin, Shehzana Hussaini, Allison G Lafferty, Shaina Bernard, Shannon Ruelle, Catherine O Dasenbrock, Meredith Sheridan, Frank Wackes, Rachna Kapoor, Ramesh Gopalaswamy, Kiran M Perkins

Abstract Background Reports of ceftriaxone serious adverse events (SAEs), including deaths, from multiple jurisdictions during December 2024–January 2025 prompted a nationwide investigation to evaluate product safety, characterize SAEs, and assess for changes in baseline adverse event occurrence via national databases. Methods In February 2025, CDC issued a national call for cases, defined as SAEs involving death or CPR within six hours of ceftriaxone injection, not otherwise explained and occurring in non-ICU sett …

03.09.2026journal-article

Frontiers in Oncology

Clinical trial design for primary brain tumors: a problem-based framework for neuro-oncology practice

Diego Gómez-Puerto, Jesús Yaringaño, Antonio Di Muzio, Oriol Mirallas, María Vieito

Background Primary brain tumor trials may produce an uninterpretable or non-generalizable answer when biological mismatch, inadequate intratumoral exposure, restrictive eligibility, molecular rarity, unstable controls, and disease-specific endpoint ambiguity are addressed separately. The practical problem is not the absence of modern methods, but failure to select and combine them according to the dominant threat to the development decision. Methods We performed a practice-facing narrative synthesis of methodologic …