EUVIMEDEuropean Health Evidence
Uhr 10/10Sources Journal Tree
Easy Demo

EUVIMED Themenbrowser · Alter & Demenz · Seite 98

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
13.08.2026journal-article

Frontiers in Aging

Intelligent health promotion system-based construction and implementation of exercise intervention for older adults with frailty and prefrailty

Mengya Liu, Li Zhang, Qin Huang, Xiaoli Zhu, Yu Wang, Lin Zhu

Background Frailty in the elderly population is increasing, and the development of high-quality clinical practice guidelines or consensuses can guide medical staff to better provide health services for frail elderly individuals. In recent years, scholars at home and abroad have actively explored exercise intervention management in elderly individuals with frailty or prefrailty. How to rapidly generalize interventions with “known and definite effects” for the community-dwelling frail elderly population is the core i …

13.08.2026journal-article

Public Health Challenges

Proceedings of the Global Health Focus Youth Conference 2025: The Role of Young People in Advancing Global Health Education, Research, and Leadership

Zhinya Kawa Othman, Don Eliseo Lucero‐Prisno, Mohamed Mustaf Ahmed, Olalekan John Okesanya, Aniekan Michael Ekpenyong, Jerico Bautista Ogaya, Goodness Ogeyi Odey, Adriana Viola Miranda, Yasir Ahmed Mohammed Elhadi, Yusuff Adebayo Adebisi

ABSTRACT Youth represent the largest and most interconnected generation but remain underserved by traditional and global health structures. In Africa alone, nearly 60% of the population is under the age of 25, and the continent's youthful population is projected to reach almost 1 billion by 2050. This narrative synthesis draws on proceedings from the 2025 Global Health Focus Youth Conference in Kigali, Rwanda, and triangulates them with recent peer‐reviewed evidence to discuss how young professionals contribute to …

13.08.2026journal-article

American Journal of Lifestyle Medicine

The Association of Diet and Lifestyle Factors With Quality of Life and Self-Rated Health in Older Adults: The Loma Linda Longevity Study

Luiz Fernando Sella, Alaa Alabadi-Bierman, Michael Paalani, W. Lawrence Beeson, Hildemar Dos Santos

Introduction: Subjective health predicts mortality in older adults. We examined associations of vegetarian diet, adherence duration, and a Healthy Lifestyle Index with quality of life (QoL) and self-rated health (SRH) in adults ≥75 years. Methods: We analyzed cross-sectional data from 421 Loma Linda Longevity Study participants using ordinal logistic regression. Three hierarchical models were estimated: M1 (diet + sociodemographic covariates), M2 (M1 + diet duration + Healthy Lifestyle Index), and M3 (final fully a …

13.08.2026journal-article

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz

Präventive Hausbesuche als Intervention zur Gesundheitsförderung älterer Menschen

Britta Blotenberg, Anne Gebert

Zusammenfassung In diesem Diskussionsbeitrag werden Präventive Hausbesuche (PHB) als niedrigschwellige, aufsuchende Beratungs- und Unterstützungsangebote zur Gesundheitsförderung älterer Menschen diskutiert. PHB können dazu beitragen, Risiken wie Sturzgefahr, soziale Isolation oder Ernährungsmängel frühzeitig zu erkennen, die Gesundheits- und Versorgungskompetenz zu stärken und selbstständige Lebensführung im häuslichen Umfeld zu unterstützen. In Deutschland existiert eine wachsende Zahl von Projekten, deren Konzep …

13.08.2026journal-article

Brain Sciences

Development and Validity Study of a Mobile Corsi Block Test for Visuospatial Working Memory in Community-Dwelling Older Adults

Dahye Ham, Eunyoung Cho, Sungwon Choi

Background/Objectives: The Corsi Block Tapping Test (CBTT) is a widely used measure of visuospatial working memory; however, its traditional paper-and-pencil administration is limited by inter-examiner variability in procedure and restricted accessibility. To address these limitations, the present study developed a Korean mobile version of the CBTT and examined its reliability and validity among community-dwelling older adults. Methods: The CBTT was administered to 120 Community-Dwelling older adults. Participants …

13.08.2026journal-article

Frontiers in Aging Neuroscience

Potential effects of β-hydroxy-β-methylbutyrate and exercise on brain aging and age-related disorders: implications for immunometabolic regulation and muscle–brain–immune crosstalk

Boyuan Shi, Zheng Han

β-Hydroxy-β-methylbutyrate (HMB), a bioactive leucine metabolite, has emerged as a potentially valuable nutritional compound with effects extending beyond skeletal muscle metabolism toward systemic immunometabolic regulation. This review summarizes evidence from 24 experimental and clinical studies regarding the potential relevance of HMB to brain aging and age-related disorders, with emphasis on mitochondrial regulation, inflammatory signaling, redox homeostasis, and exercise-associated adaptations. Most studies r …

13.08.2026journal-article

Sensors

Brain Activity and Connectivity in Fatigued People with Multiple Sclerosis During a Static Balance Task: An fNIRS Study

Davide Cattaneo, Alessandro Torchio, Augusto Bonilauri, Chiara Corrini, Nora E. Fritz, Francesca Baglio, Elisa Gervasoni

Fatigue and balance disorders are common in people with multiple sclerosis (PwMS), but the neural mechanisms linking them during postural control remain unclear. This cross-sectional study aims to examine associations between fatigue, balance impairment, and task-evoked cortical hemodynamics/connectivity. Sixteen PwMS (relapsing-remitting MS; EDSS < 3.5) and 19 healthy controls (HC) were enrolled. Based on the Modified Fatigue Impact Scale (MFIS), PwMS were classified as fatigued (f_PwMS, MFIS ≥ 38; n = 10) or non- …

13.08.2026journal-article

Frontiers in Aging Neuroscience

The molecular mechanisms of Guizhi Fuling Pills in ameliorating Alzheimer’s disease-like cognitive impairment: insights from transcriptomics, metabolomics, and gut microbiome

Lan Ma, Jing Wang, Zhenghao Xu, Zuxiu Huang, Kelong Chen, Xiaoqiong Teng, Miao Chen, Shuyang Lin, Rong Zhou

Background Alzheimer’s disease (AD)-like cognitive impairment, as a major type of cognitive disorder, has witnessed a sharp rise in prevalence. Therefore, there is an urgent need to develop effective therapeutic intervention measures. Guizhi Fuling Pills (GFP), a classical Traditional Chinese Medicine (TCM) formula, has been shown to exert protective effects on cognitive function. However, its underlying mechanisms remain unclear. Objective To investigate the effects of GFP on AD-like cognitive impairment and eluci …

13.08.2026journal-article

Advanced Engineering Materials

Effects of Aging Heat Treatment and Pore Architecture on the Microstructure and Compressive Behavior of Porous 17‐4PH Stainless Steel

Ting‐Yu Kuo, Yu‐Chih Tzeng, Chien‐Hsin Yao, Tzu‐Hung Ma

This study investigates the combined effects of aging heat treatment and pore architecture on the microstructure, compressive behavior, and energy absorption performance of porous 17‐4PH stainless steel. Homogeneous, mixed pore‐size, stepwise gradient, and layered porous structures with a fixed porosity of 50% were fabricated using pressureless slurry sintering. Microstructural analyses reveal that aging at 480 °C promotes the formation of fine nanoscale Cu‐rich precipitates (CRPs) within the martensitic matrix, th …

13.08.2026journal-article

Journal of Alzheimer’s Disease

Mental illness among persons with and without dementia in continuing care: A multi-jurisdictional, repeated cross-sectional study

Joey Champigny, David B. Hogan, Ruth Ann Marrie, Jin Luo, Xueyi Chen, Okechukwu Ekuma, Randy Walld, Erind Dvorani, James M. Bolton, Zahra Goodarzi, Ping Li, Dallas Seitz, Andrea Gruneir, Matthias Hoben, Nathan Herrmann, Luke Mondor, Colleen J. Maxwell, on behalf of the EMHLTH-CC Research Team

Background Limited epidemiologic data exists for mental illnesses among at-risk home care (HC) and residential long-term care (LTC) recipients. Objective To estimate the annual prevalence (April 1, 2012-March 31, 2023) of various mental illnesses among HC and LTC populations (versus matched comparators) with and without dementia in the Canadian provinces of Ontario, Alberta, and Manitoba. Methods Parallel repeated cross-sectional studies were conducted in each province using linked health administrative data. HC an …

13.08.2026journal-article

Cell Death & Disease

Neuronal AIMP2–α-synuclein synergy drives endogenous tau and amyloid-β pathologies and neurodegeneration in a mechanistic model of Lewy body dementia

Doeun Kim, Heejeong Kim, Ji Hun Kim, Hyojung Kim, Joo-Ho Shin, Han Seok Ko, Eunyoung Moon, Hee-Seok Kweon, Yunjong Lee

Abstract Lewy body dementia (LBD), encompassing Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB), is defined by widespread α-synuclein (αSyn) aggregation and frequently exhibits coexistent tau and amyloid-β (Aβ) pathologies. However, whether αSyn pathology is sufficient to drive endogenous tau and Aβ aggregation has remained unclear due to a lack of in vivo models that recapitulate the full spectrum of LBD-associated proteinopathies and neurodegeneration. AIMP2, a parkin substrate that accumul …

13.08.2026journal-article

Advanced Electromagnetics

Positive Effects of Solution-Focused Short-Term Therapy Combined with Routine Nursing Care on the Psychological State and Quality of Life of Patients with Geriatric Syndromes

W. J. Ye, Q. Li, Q. Wang, Z. L. Liu

Patients with geriatric syndromes often show limited improvement in psychological state and quality of life after routine care alone. This study applies a structured solution-focused brief therapy intervention combined with routine nursing care, guiding patients to focus on personal strengths and achievable goals through six standardized sessions. The intervention is implemented by uniformly trained nursing staff according to an operating manual, ensuring procedural consistency and scalability. At the 4-week follow …

13.08.2026journal-article

American Journal of Hematology

Development and Validation of a Novel Geriatric Risk Score for Prognostication in Older Patients With Hodgkin Lymphoma: A Multicenter Retrospective Study

Peiqi Zhao, Yihan Wang, Min Bai, Chen Huang, Jiesong Wang, Yajun Li, Yanan Jiang, Ganggang Wang, Feng Zhu, Shu Zhao, Wei Guo, Shukai Qiao, Jianxia He, Ji Ma, Yanyan Zhang, Lei Zhu, Li Li, Wenyue Yu, Shaozhen Chen, Junqing Xu, Ou Bai, Hui Zhou, Qingyuan Zhang, Liping Su, Yuanlin Xu, Huilai Zhang

ABSTRACT Outcomes in older patients with Hodgkin lymphoma (HL) are compromised by the interplay of patient frailty and disease aggressiveness; however, current stratification tools, including the International Prognostic Score (IPS) and Comprehensive Geriatric Assessment (CGA), lack sufficient prognostic discrimination in the older HL population. We developed and validated a prognostic model integrating metabolic tumor burden and geriatric assessment. In this retrospective study across 14 centers in China between 2 …

13.08.2026journal-article

International Journal of Molecular Sciences

Duration of Caloric Restriction Modulates Brain Redox Adaptation and Frailty During Aging

Desanka Milanovic, Sladjan Pavlović, Milica Prvulovic, Slavica Borković Mitić, Srdjan Sokanovic, Smilja Pracer, Aleksandra Mladenovic

Caloric restriction (CR) is among the most effective nutritional interventions for promoting healthy aging, yet the influence of intervention duration and age at initiation on its efficacy remains incompletely understood. This study investigated the effects of short-term caloric restriction (STCR) and long-term caloric restriction (LTCR) on frailty and brain redox homeostasis in male Wistar rats. Animals were maintained under ad libitum (AL) feeding, or subjected to LTCR initiated at 6 months of age or STCR initiat …

13.08.2026journal-article

JMIR Formative Research

Understanding the Prospective Acceptability of a Fall Prevention Exercise App Among Canadians Aged 50 Years and Older Living in the Community: Mixed Methods Study

Maria Fernanda Fuentes Diaz, Kathryn May Sibley, Chinasa Obiageri Trinitta Ugwuegbulem, Kim Delbaere, Danielle R Bouchard

Abstract Background Falls are a major public health concern due to their impact on individuals and the health system. StandingTall (Ylva Health Pty Ltd) is a digital balance exercise app that has demonstrated strong adherence and fall-reduction effects in Australia. Before considering implementation in Canada, its acceptability must be assessed. Objective This study aimed to explore the prospective acceptability of the StandingTall app among Canadian community-dwelling adults aged 50 years and older with varying le …

13.08.2026journal-article

Physiological Measurement

Comparison of activPAL and ActiGraph measured moderate to vigorous physical activity in people with COPD

Jung Yoen Son, Katelyn Webster-Dekker, Deanna J Marriot, She’Lon Tucker, Janet L Larson

Abstract Objective. ActiGraph accelerometers are commonly used to assess moderate-to-vigorous physical activity (MVPA), but there are concerns about missing data due to compliance issues with hip-worn devices. ActivPAL devices are worn 24 h d −1 on the anterior thigh, minimizing missing data, but activPAL software does not directly estimate MVPA. This study aimed to evaluate the agreement between MVPA derived from activPAL (using five methods) and ActiGraph data (using two methods) among individuals with chronic ob …

13.08.2026journal-article

Frontiers in Psychiatry

Study on multi-modal feature fusion machine learning classification model of Chinese and Western medicine for depressive symptoms in middle-aged and older patients with chronic low back pain

Bo Jin, Juan Gao, Chenying He, Xiaohong Lei

Objective To construct a machine learning classification model integrating multi-modal features of Chinese and Western medicine for screening the risk of depressive symptoms in middle-aged and older patients with chronic low back pain (CLBP). Methods A cross-sectional design included 370 CLBP patients aged ≥45 years admitted to our hospital from January 2022 to June 2024. Based on PHQ-9 scores, they were classified into depression (≥10) and non-depression (<10) groups. Chinese and Western medicine characteristics w …

13.08.2026journal-article

Journal of Applied Gerontology

Social and Physical Activity Participation Among Older Adults With Disability: The Interplay of Senior Housing and Perceived Social Cohesion

Byeongju Ryu, BoRin Kim, Sojung Park, Jihye Baek

Residential environments are critical factors influencing activity participation among older adults with disabilities. We examined whether living in senior housing (i.e., retirement communities or independent living) is associated with participation in social and physical activities and whether this association varies by perceived social cohesion. Data came from 3317 respondents in the 2019 National Health and Aging Trends Study who reported difficulty with self-care, mobility, or household tasks. Weighted logistic …

13.08.2026journal-article

Jurnal Ekonomi & Keuangan Islam

What drives people to invest in cash waqf linked sukuk with trust mediation?

Erny Arianty, Syanni Yustiani, Iin Indrawati, Muhammad Iqbal Balative

Purpose – This study aims to examine the factors influencing Indonesians’ investment intentions toward cash waqf-linked sukuk (CWLS).Methodology – This study adopted a quantitative research design using structural equation modeling (SEM). Data were collected from Indonesian respondents who met the predetermined eligibility criteria, resulting in 106 valid response. The proposed model examines the determinants of investment intention toward cash waqf-linked sukuk (CWLS), with religiosity incorporated as a moderating …

13.08.2026journal-article

Jurnal Biologi Tropis

Vascular Cognitive Impairment and Vascular Dementia: A Literature Review

Azka Fadila Latifa, Annisa Fitria Zahra AS, Muhammad Fatih Ma'ruf, Novad Sawelly, Dini Suryani, Herpan Syafii Harahap

Vascular Cognitive Impairment and Dementia (VCID) is a spectrum of cognitive disorders associated with cerebrovascular disease and is a major cause of cognitive decline and dementia in older adults. This study aimed to review the etiology, risk factors, pathophysiology, diagnostic evaluation, and management of VCID to support early detection and appropriate intervention. A literature review was conducted using relevant scientific publications and clinical guidelines addressing VCID. The findings indicate that VCID …

13.08.2026journal-article

Diabetes Care

Housing Instability Associated With Cost-Related Nonadherence and Financial Toxicity in People With Uncontrolled Diabetes

Victoria H. Davis, Roshanak Mehdipanah, Minal R. Patel

OBJECTIVE To assess the prevalence of housing instability and its associations with cost-related nonadherence and financial toxicity among adults with uncontrolled diabetes. RESEARCH DESIGN AND METHODS We analyzed baseline randomized controlled trial data from 600 adults with uncontrolled diabetes and cost-related barriers to care. Logistic and linear regression assessed associations of housing instability with cost-related nonadherence and financial toxicity. RESULTS Half (n = 298) reported housing instability, wh …

13.08.2026journal-article

The Milbank Quarterly

Public Policies in Historical Context and the Association Between Education and US Older Adults’ Health

MARK D. HAYWARD, MATEO P. FARINA

Policy Points Improving population health while reducing inequality is possible, but it depends on broad institutional investments whose benefits extend across the socioeconomic distribution rather than accruing primarily to the advantaged. The education–health gradient is sensitive to the race between technology and education. Recent advances have disproportionately benefitted college‐educated persons, and differential automation risk and unequal access to therapeutics, such as GLP‐1 agonists, may widen these gaps …

13.08.2026journal-article

Materials Research Express

Moisture, aging, and interfacial microstructure of dry-process modified stone mastic asphalt: MA-CK and MA-123 benchmarked against SBS

Ali Almusawi, Ceren Keleş

Abstract Stone mastic asphalt (SMA) conventionally relies on wet-process Styrene–Butadiene–Styrene (SBS) modification to meet demanding rheological requirements, yet the specialized blending infrastructure this entails has sustained interest in dry-process alternatives. This study presents an independent, standards-based comparative evaluation of SMA mixtures modified with two commercially available dry-process polymer composites, MA-CK and MA-123 (PROpolymer, Ruschemicals Group), benchmarked against SBS at their m …

13.08.2026journal-article

European Journal of Ageing

Determinants of life expectancy with unmet needs in the Chinese older population (revision 1)

Hui Wang, Bo Hu

Abstract This study investigates the determinants of and disparities in life expectancy (LE) with unmet long-term care needs among older people in China. The data come from four waves of the China Health and Retirement Longitudinal Study (CHARLS), a nationally representative survey conducted between 2013 and 2020 (N = 42,480). Continuous time multi-state Markov modelling is combined with the life table approach to estimate the total life expectancy and life expectancy with met and unmet needs. Chinese older people …