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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Developmental Medicine & Child Neurology

Risk factor profiles in infants born preterm and at term with cerebral palsy in Argentina: Findings from the Argentine Cerebral Palsy Register

M. Mercedes Ruiz Brunner, Carla Gil, María Elisabeth Cieri, Ana Laura Condinanzi, L. Johana Escobar Zuluaga, Federico Sanchez, Gulam Khandaker, Israt Jahan, Nadia Badawi, Eduardo Cuestas

Aim To describe the patterns of co‐occurrence between previously documented risk factors and gestational age in infants with cerebral palsy (CP) registered in the Argentine Cerebral Palsy Register (Registro Argentino De Parálisis Cerebral [RAR‐PC]). Method This register‐based, cross‐sectional study analysed data from individuals with confirmed CP registered in the RAR‐PC. Family interviews and medical record reviews were conducted. The variables analysed included CP characteristics, a predefined set of prenatal, pe …

03.09.2026journal-article

Journal of Travel Medicine

Orthopaedic Injuries among International Travellers in Nepal

Abhishek Shrestha, Ishwor Ghimire Padhya, Jasmine Shrestha, Pratigya Aryal, Prativa Pandey

Highlight/Teaser International travellers in Pokhara experience a considerable burden of orthopaedic injuries. This study describes their injury patterns, management, and outcomes, providing evidence to strengthen preventive advice, trauma preparedness, and clinical services in popular adventure-travel destinations.

03.09.2026journal-article

PLOS One

Trends, patterns, determinants and socio-economic inequality of high-risk fertility behavior (HRFB) among Bangladeshi women: Evidence from Bangladesh Demographic and Health Surveys

Raisha Binte Islam, Syed Toukir Ahmed Noor

Background Globally and in Bangladesh, high-risk fertility behavior (HRFB) continues to be a significant public health issue, contributing to negative health outcomes for both mothers and children. Therefore, this study aimed to evaluate the trends, prevalence, determinants, and socio-economic inequalities associated with HRFB among presently married women of reproductive age by utilizing data from the Bangladesh Demographic and Health Survey (BDHS). Methods We analyzed data from 19,060 currently married women aged …

03.09.2026journal-article

Frontiers in Surgery

When microsurgery is not an option: staged delayed reverse sural artery flap with ischaemic preconditioning for limb salvage in an elderly patient with chronic post-traumatic osteomyelitis—a case report

Zhun Shen Tan, Adzim Poh Yuen Wen, Farzana Ansarutheen, Mohd Yazid Bajuri

Lower extremity reconstruction in elderly patients with post-traumatic osteomyelitis presents a formidable challenge. We report a 70-year-old female with hypertension, dyslipidaemia, and bilateral knee osteoarthritis who sustained a Gustilo-Anderson type IIIB open right ankle fracture with exposed calcaneus following a fall. The course was complicated by chronic osteomyelitis, managed with partial talectomy and total calcanectomy, antibiotic-impregnated cement spacer placement, cement exchange and prolonged culture …

03.09.2026journal-article

Frontiers in Natural Products

Antifungal and antibiofilm activity of crude hydroalcoholic extract and fractions of Myrcia neoobscura leaves against a clinical isolate of Candida krusei

Leticia Bachmann, Eduarda Rensi Botelho, Patrícia Helena Arrabal, Pâmela Elise Munzlinger, Patryne Luana da Silva Dantas, Larissa Mascarenhas Krepsky, Lucas Ferriolli Mariotto, Michele Debiasi Alberton, Tatiani Karini Rensi Botelho

Infections caused by biofilm-forming Candida sp. Are responsible for high morbidity and mortality rates. With the scarcity of therapeutic options and the increase in resistance to antifungal drugs, new treatment options are needed. Myrcia neoobscura is a tree endemic to the Atlantic Rainforest, belonging to the genus Myrcia , several of whose species have demonstrated important antifungal activities. The aim of this study was to evaluate the antifungal and antibiofilm activity of the crude hydroalcoholic extract an …

03.09.2026journal-article

Frontiers in Medicine

Case Report: Electrode perforation with normal pacemaker parameters leading to hemorrhagic shock: a rare case report of the “penetration-exit-re-entry” phenomenon

Zuoan Qin, Jian Yang, Li Luo, Shi Chen, Fei Yang

Background Permanent pacemaker implantation via subclavian vein puncture may induce rare but life-threatening iatrogenic vascular injury. Vascular perforation with pacing lead penetration-exit-re-entry trajectory accompanied by normal intraoperative pacing parameters is reported extremely rarely, which greatly increases the risk of missed diagnosis. Case presentation A 70-year-old female patient with complete atrioventricular block received dual-chamber pacemaker implantation. All intraoperative lead electrical ind …

03.09.2026journal-article

Frontiers in Cardiovascular Medicine

Perfluorooctanoic acid–associated complement factor B upregulation and atrial fibrillation–related molecular alterations: integrated network toxicology, Mendelian randomization, molecular dynamics, and HL-1 cell analyses

Dan Li, Chuanfeng Bai, Jinping Zhao

Background Perfluorooctanoic acid (PFOA) is a persistent environmental pollutant associated with cardiovascular dysfunction, but the molecular links between PFOA exposure and atrial fibrillation (AF) remain unclear. We aimed to prioritize a candidate mediator connecting PFOA with AF and examine its associated molecular effects in atrial cardiomyocytes. Methods PFOA-associated or computationally predicted genes from CTD, STITCH, and SwissTargetPrediction were integrated with AF-associated genes. Complement factor B …

03.09.2026journal-article

Frontiers in Psychology

Animal-assisted resilience in space exploration: a human factors approach to astronaut behavioral health

David W. Kim

Space science has been developed through past and current missions of the International Space Station (ISS) and Artemis (I and II) in low Earth orbit and on the lunar surface. Numerous missions have used animals on test flights to better understand the physiological dangers of space flight for humans. A contemporary focus of space exploration is long-duration crewed travel to establish a Moon station and reach Mars. The astrotechnology of the human-less spaceflights (USA, Russia, ESA, UAE, China, and India) launche …

03.09.2026journal-article

Frontiers in Medicine

Case Report: A cluster of cases with rash associated with Chlamydia pneumoniae infection

Tianyi Wu, Gang Wang, Nannan Xu, Ke Xu, Gonghai Chen

We report a case of clustered rashes among teenagers associated by Chlamydia pneumoniae (CP) infection. Most patients only presented with rashes without significant fever or other respiratory tract symptoms. Metagenomic next-generation sequencing (mNGS) of blood samples identified the culprit - the nucleic acid sequence of CP was detected in the peripheral blood of the index case. The results of targeted next-generation sequencing (t-NGS) of throat swabs further supported the presence of CP. After antibiotic treatm …

03.09.2026journal-article

Frontiers in Cardiovascular Medicine

Combined assessment of carotid intima–media thickness and epicardial fat thickness for cardiovascular risk stratification in asymptomatic South Indian adults

Ramesh Sankaran, Dolly Agarwal, Rahul Mittal, Shankar Srinivasan, Nagendra Boopathy Senguttuvan, Alex Karev, Sadhanandham Shanmugasundaram, Balasubramaniyan Jayanthi Venkata, Vinod Kumar Balakrishnan, Preetam Krishnamurthy, Sadagopan Thanikachalam, Murthy Jayanthi Satyanarayana

Background Carotid intima-media thickness (cIMT) and epicardial fat thickness (EFT) are non-invasive imaging markers associated with cardiovascular risk. This study evaluated the associations between cIMT, EFT, individual cardiovascular risk factors, cumulative cardiovascular risk-factor burden in asymptomatic adults undergoing routine cardiovascular health assessment. Methods A cross-sectional study was conducted in 925 asymptomatic adults aged ≥18 years undergoing routine cardiovascular health evaluations. Partic …

03.09.2026journal-article

El-Mal: Jurnal Kajian Ekonomi & Bisnis Islam

The Effect of Workload, Professionalism, Incentives and Work Motivation on Health Worker Performance

Minarni Purnaningsih, Istiatin Istiatin, Oong Ridhoi

This study aims to analyze the influence of workload, professionalism, incentives, and work motivation on the performance of health workers at Dr. RM. Soedjarwadi Regional Mental Hospital, Central Java Province, both partially and simultaneously. This study uses a quantitative approach with a survey method. The research sample is 25% of all health workers directly involved in patient care at Dr. RM. Soedjarwadi Regional Mental Hospital, excluding medical personnel (doctors), with an incidental sampling technique. D …

03.09.2026journal-article

Journal of Feline Medicine and Surgery Open Reports

EXPRESS: Use of subconjunctival cyclosporine implants for treatment of feline eosinophilic keratoconjunctivitis: a case report

Lynn Willems, Jordan Kay Roberts

Case summary A 5-year-old neutered male domestic shorthair cat was presented for evaluation of chronic bilateral eosinophilic keratoconjunctivitis (EK). The patient had a history of recurrent corneal plaques and conjunctivitis that were initially managed with systemic and topical immunosuppressive therapy. Long-term disease control was limited by poor tolerance of topical ophthalmic medications, resulting in inconsistent treatment and repeated disease recurrence affecting both eyes. Over several years the cat was t …

03.09.2026journal-article

Borneo Nursing Journal (BNJ)

Pengaruh Pemberian Terapi Titik Tekan (Akupresur) Dalam Mengurangi Post Operative Nausea And Vomiting (PONV) Pada Pasien Dengan Anestesi Spinal Di RSI Sultan Agung Semarang

Nur Andriani Ningsih, Anita Setyowati, Ratih Kusuma Dewi

Background: Postoperative Nausea and Vomiting (PONV) is one of the most commoncomplications following surgical procedures performed under spinal anesthesia. This conditioncan cause discomfort, delay recovery, and increase the risk of postoperative complications. Onenon-pharmacological intervention that may help reduce PONV is acupressure therapy,particularly stimulation of the Pericardium 6 (P6) acupressure point. Objective: This study aimsto determine the effect of acupressure therapy on reducing the incidence of …

03.09.2026journal-article

Biomedical Informatics and Smart Healthcare

Advanced Architectures in Preventive Health Informatics: A Hybrid Clinical Decision Support System for Early Endocrine and Metabolic Risk Screening

Rahul Sharma

Contemporary medicine is shifting from reactive, symptom-based treatment toward proactive, preventive intervention, yet endocrine and metabolic disorders frequently progress through subtle, subclinical phases that are overlooked during routine primary-care encounters, delaying diagnosis and increasing the longitudinal cost of care. This paper presents EndocrineAI, a full-stack, high-integrity clinical decision support system (CDSS) for early-stage endocrine and metabolic risk screening. The platform adopts a hybrid …

03.09.2026journal-article

Journal of Health Psychology

Development and psychometric evaluation of the illustrated hospital fear scale for preschool children

Tülay Kuzlu Ayyıldız, Kübra Akgün Emiroğlu, Musa Özsavran

Hospital-related fear is a significant source of distress for preschool children, yet existing assessment tools are not adequately suited to their developmental level. This methodological study aimed to develop the Illustrated Hospital Fear Scale for Preschool Children and evaluate its psychometric properties. The study was conducted with 300 preschool children aged 4–6 attending educational institutions in western Türkiye. Scale development proceeded through four stages: item generation, expert review, pilot testi …

03.09.2026journal-article

Public International and Private International Law

Tax Sovereignty and International Legal Guarantees for the Protection of Foreign Investments: Synergy or Competition?

Yulia A. Krokhina

Taxation is traditionally considered a key manifestation of state sovereignty, as it is through tax mechanisms that the state ensures the formation of public finances, the redistribution of resources, and the implementation of socio-economic functions. Changes in tax legislation and aggressive tax administration can affect the property interests of investors so significantly that they raise the question of whether they qualify as indirect expropriation of capital. Based on a study of international arbitration pract …

03.09.2026journal-article

Journal of Associated Medical Sciences

Impact of self reflection training using Kawa model on quality of life and Academic performance among occupational therapy students

Associate professor, Saveetha College of Occupational Therapy, Saveetha Institute of Medical and Technical Sciences , Chennai, Tamilnadu, India., Punitha P, Sofia Williams, Occupational therapist, Saveetha College of Occupational Therapy, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamilnadu, India.

Background: Self-appraisal and reflection are crucial for occupational therapy students (OT) and practitioners, fostering learning and professional growth. The Kawa model, typically used clinically, may aid self-reflection by helping students recognize their strengths and challenges. However, while the model has been extensively studied in clinical settings, research on its application as a self-reflection tool for OT students remains limited. Objectives: This study aimed to evaluate the impact of self-reflection t …

03.09.2026journal-article

Journal of Risk and Financial Management

Professional Judgment and AI Disclosure Governance in Audit and Sustainability Assurance: Public Evidence from the UK Big Four

Radosveta Krasteva-Hristova

Artificial intelligence (AI) is entering audit workflows while sustainability reporting expands the evidence subject to professional evaluation. This exploratory study examines how the UK Big Four publicly describe safeguards that keep AI-assisted work human-led, reviewable and accountable. The complete 2024 transparency-report cross-section was coded against seven pre-specified dimensions and summarized in an AI–Judgment Governance Disclosure Index (AI-JGDI). The index measures AI disclosure governance—the complet …

03.09.2026journal-article

Clinical Research in Cardiology

Gaps in lipid management among high-risk patients without prior MI or stroke: the VESALIUS-REAL global study

Queenie Chan, Jaimini Cegla, Ulrich Laufs, Jan H. Cornel, Gaetano M. De Ferrari, Emil Hagström, Huei-Kai Huang, José Lopez-Miranda, Suna Avcil, Corinne Brooks, Thomas Cars, Adrienne Y. L. Chan, Celine S. L. Chui, Michael Duxbury, Edward Chia-Cheng Lai, David Neasham, Andreas Ochs, James O’Kelly, Gabriel Paiva da Silva Lima, Naomi Reimes, Swati Sakhuja, Shih-Chieh Shao, Ju-Young Shin, Mahendra Sibartie, Ilona Verburg, Matthew J. Budoff, Kyung Woo Park, Kenichi Tsujita, Kai Hang Yiu, Nafeesa Dhalwani, Ian C. K. Wong

Abstract Background Real-world evidence on lipid-lowering therapy (LLT) use and low-density lipoprotein cholesterol (LDL-C) control in patients at high cardiovascular (CV) risk without prior myocardial infarction (MI) or stroke remains limited. We evaluated LLT use, treatment intensification, LDL-C monitoring, and LDL-C goal attainment across North America, Europe, and Asia-Pacific. Methods VESALIUS-REAL is a retrospective observational study using a common protocol across 11 databases between 2017 and 2022. Eligib …

03.09.2026journal-article

Clinical Microbiology Reviews

Human vascular pythiosis: pathogenesis, diagnosis, and evidence-informed management

Nitipong Permpalung, Sadeep Medhasi, Pattama Torvorapanit, Rongpong Plongla, Navaporn Worasilchai

SUMMARY Human vascular pythiosis is a rare, life-threatening angioinvasive infection caused predominantly by the oomycete Pythium insidiosum . Unlike ocular or cutaneous pythiosis, the vascular form is defined by arterial wall invasion, long-segment thrombosis, limb ischemia, aneurysmal complications, and high risks of amputation and death. Although P. insidiosum is broadly distributed in freshwater environments, reported human vascular disease remains concentrated in Thailand, indicating that exposure alone is ins …

03.09.2026journal-article

European Journal of Clinical Microbiology & Infectious Diseases

Diagnosis of pneumococcal pneumonia using quantitative PCR targeting lytA and piaB in adult patients with community-acquired pneumonia

Nienke Paternotte, Willem R. Miellet, Tessa Nieuwenhuijsen, Rob Mariman, Wil A. van der Reijden, Wouter Rozemeijer, Elisabeth A.M. Sanders, Dominic Snijders, Cornelis H. van Werkhoven, Marc J.M. Bonten, Krzysztof Trzciński, Wim G. Boersma

Abstract Purpose Accurate diagnosis of pneumococcal pneumonia remains challenging due to suboptimal sensitivity of conventional microbiological methods. Molecular techniques may improve Streptococcus pneumoniae detection, but their clinical utility remains uncertain. Methods In this prospective observational study, we compared conventional diagnostics with qPCR-based detection of lytA and piaB genes in nasopharyngeal, oropharyngeal, saliva, and sputum samples collected from adults with community-acquired pneumonia …

03.09.2026journal-article

Academic Bulletin of Mental Health

Disulfiram-Induced Catatonia Following a Disulfiram–Alcohol Reaction: A Case Report

Satyasmita Jena, Rakesh Kumar Jangde, Rachana Chandekar, Priyansh Dubey

Disulfiram is commonly used in the management of alcohol dependence. Although generally safe, it may rarely lead to neuropsychiatric adverse effects such as catatonia. We report a case of a 32-year-old male with alcohol dependence who developed acute catatonic symptoms following a disulfiram–alcohol reaction after unsupervised use of disulfiram. Such cases, though previously reported, remain uncommon in clinical practice, particularly in settings like Chhattisgarh where unsupervised disulfiram use and limited aware …

03.09.2026journal-article

Journal of Clinical Medicine

Association Between DLCO and Echocardiographic Right Ventricular–Pulmonary Arterial Coupling in Idiopathic Pulmonary Fibrosis

Francesca Coppi, Susan Darroudi, Giulia Renda, Alessandra Lodeserto, Arianna Maini, Damiano De Cesare, Youssef Othman, Martina Mercati, Dalia Caleffi, Filippo Gozzi, Francesco Marangi, Dario Andrisani, Federica Andolfi, Alessio Baccarani, Daniela Aschieri, Anna Vittoria Mattioli, Francesco Fedele, Enrico Clini, Stefania Cerri, Gianluca Pagnoni

Background: Idiopathic pulmonary fibrosis (IPF) is frequently complicated by pulmonary vascular involvement and right ventricular (RV) dysfunction, both of which adversely affect prognosis. The relationship between impaired gas exchange and echocardiographic indices of RV function, particularly the TAPSE/PAPs (tricuspid annular plane systolic excursion/systolic pulmonary artery pressure) ratio as a marker of RV–pulmonary arterial (RV–PA) coupling, has not been fully characterized. Methods: We retrospectively evalua …

03.09.2026journal-article

Journal of Clinical Medicine

The Association of SARIFA with Poor Prognosis and Aggressive Tumor Phenotypes in Cancers: A Meta-Analysis

Jiaqi Lao, Guangwei Tian, Lin Guan

Background: SARIFA (Stroma Areactive Invasion Front Areas) is an emerging histopathological biomarker defined by direct tumor–adipocyte contact at the invasive front. Preliminary studies suggest its association with poor prognosis, but evidence remains fragmented across cancer types. This meta-analysis aims to systematically evaluate the prognostic value of SARIFA for overall survival (OS) and its correlation with aggressive tumor phenotypes. Methods: Following PRISMA guidelines, we searched PubMed, Embase, Web of …