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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
02.09.2026journal-article

Practice Nursing

Chikungunya in older people: a guide for primary care nurses

Victoria Browne, Nicky Longley, Jessica Manson, Anna M Checkley

Chikungunya is a mosquito-borne viral infection with an expanding global spread, driven by climate change and increased international travel, leading to more older people and people with long-term health conditions travelling abroad. Chikungunya is characterised by sudden-onset fever and severe joint pain; however, older adults may present atypically, with milder or absent fever and non-specific symptoms, increasing the risk of delayed diagnosis. Pre-travel advice, vaccination and mosquito bite avoidance are key fo …

02.09.2026journal-article

Revista Ibero-Americana de Humanidades, Ciências e Educação

P-TAU217 COMO BIOMARCADOR SANGUÍNEO NO DIAGNÓSTICO PRECOCE DA DOENÇA DE ALZHEIMER: UMA REVISÃO DA LITERATURA

Paulo Eduardo Macedo de Moraes Filho, Victor Monteiro Campos, Ana Carolina de Moraes Bueno, Maria Eduarda Monteiro Pereira da Silva, Maria Aparecida de Almeida Souza Rodrigues

A doença de Alzheimer (DA) é uma enfermidade neurodegenerativa progressiva cuja fisiopatologia envolve, entre outros mecanismos, o acúmulo cerebral de β-amiloide, associado a alterações da proteína tau, sua hiperfosforilação e formação de emaranhados neurofibrilares, contribuindo para a disfunção sináptica e a perda neuronal. Essas alterações podem ocorrer anos antes do surgimento das manifestações clínicas, reforçando a necessidade de estratégias capazes de identificar a doença em estágios iniciais. Nesse contexto …

02.09.2026journal-article

F1000Research

Clinical Phenotype of Apoe Ɛ4 Carriers In Patients With Vascular Dementia: A Cross-Sectional Study From Indonesia

Siti Giranti Ardilia Gunadi, Yusran Ady Fitrah, Gita Vita Soraya, Alfi Raudatil Jannah, Andi Weri Sompa, Muhammad Iqbal Basri, Lilian Triana Limoa, Norikazu Hara, Akinori Miyashita, Takeshi Ikeuchi, Muhammad Akbar

Background Vascular dementia (VaD) is the second most common cause of dementia and exhibits substantial heterogeneity in cognitive, functional, and radiological manifestations. Despite the observed differences in clinical presentation, the factors responsible for this variability have not been clearly identified. While the apolipoprotein E ( APOE ) ε4 allele is widely known to increase the risk of Alzheimer’s disease, its contribution to the manifestation of VaD symptoms remains inadequately explored, particularly …

02.09.2026journal-article

Applied Sciences

Hybrid Decorative Elements Inspired by Textile Heritage for Furniture: Design and Influence of Coating on the UV-Accelerated Aging Behavior

Antonela Lungu, Maria Cristina Timar, Camelia Coșereanu, Marta Modi

Integrating traditional textile heritage into contemporary furniture design offers an innovative way to preserve cultural identity through modern materials and decorative techniques. This study investigates the color stability of hybrid decorative plywood panels fabricated using mechanical perforation and sewing techniques inspired by traditional textile motifs. The samples were evaluated using UV-induced artificial aging, alongside color measurements before and after exposure, microscopic analysis, and Fourier Tra …

02.09.2026journal-article

npj Dementia

Psychosocial interventions in childhood dementia: a call for action

Mustafa Atee, Rebecca Lloyd, Kristina L. Elvidge, Gail Hilton, Thomas Morris

Abstract Childhood dementia (CD) is a complex, rare, often under-recognised, and incurable neurogenetic group of disorders with neuromotor-behavioural symptoms and poor survival outcomes. Despite profound impacts, CD remains neglected and underfunded compared to other paediatric diseases. Psychosocial and rehabilitation interventions, widely recognised as valuable in adult dementia, are underexplored in CD. Integrating these supports into policy, expanding research investment and formally recognising CD are critica …

02.09.2026journal-article

Bulletin of the National Research Centre

Hepatitis B virus seroprevalence, associated factors, and liver fibrosis burden among people living with HIV in Uganda: a systematic review

Henry Kenric Kinene, Raha Zihindula, Tambwe Patrick Rodrigue, Bigabwa Baharanyi Dominique

Abstract Background Hepatitis B virus (HBV) and HIV coinfection remains an important cause of liver-related morbidity and mortality in sub-Saharan Africa. Uganda carries a substantial burden of both infections, yet evidence on HBV seroprevalence, associated factors, and liver fibrosis among people living with HIV (PLHIV) has not been comprehensively synthesized. This systematic review aimed to summarize available evidence from Uganda on HBV seroprevalence, correlates of HBV infection, and liver fibrosis burden amon …

02.09.2026journal-article

Revista DCS

CHALLENGES DURING ADOLESCENCE FOR PEOPLE WITH AUTISM SPECTRUM DISORDER

José Orlando da Silva Queiroz, Natanael Barros Gonçalves, Danyely Almeida Lopes Pinto, Naiana Ribeiro Azevedo, Luiz Carlos Gomes Sousa da Silva, Ana Célia dos Anjos Oliveira, Keyla Suellen Rocha Neves, Amanda Cristina Medeiros da Silva, Ayres Fran da Silva e Silva, Elenson Gleison de Souza Medeiros, Priscilla Andrade Silva

Adolescence in Autism Spectrum Disorder (ASD) is a phase that can present specific challenges, as characteristics of the spectrum — Such as difficulties with social communication, sensitivity to sensory stimuli, and repetitive behavior patterns — can affect adaptation to the environment. The objective of this study on adolescence in ASD is to understand how this developmental phase affects young people with ASD, considering the physical, emotional, social, and cognitive changes characteristic of this period. The st …

02.09.2026journal-article

BMC Health Services Research

What characterizes first-time use of eldercare? A SNAC Stockholm Eldercare registry-based study of older people’s health and care needs in Sweden

Pernilla Alencar Siljehag, Åsa von Berens, Bettina Meinow, Carin Lennartsson, Janne Agerholm

Abstract Background As populations age, it is becoming more important than ever to understand how older people’s care needs can be met and to ensure that local care providers are coordinated effectively. Describing older adults’ demographic characteristics, functional status, health status, and patterns of healthcare use leading up to their first-time use of eldercare provides valuable knowledge. This can facilitate the mobilization of expertise and methods in eldercare and healthcare and contribute to the joint pl …

02.09.2026journal-article

The Family Journal

Cracks in the Foundation: Childhood Violence Exposure and Romantic Relationships Among Partnered Older Adults

Sean Sorrick, Kassie R. Terrell, Hanadi Y. Hamadi, Alexa Mejido

The consequences of adverse childhood experiences on children, adolescents, and young adults are well documented; however, a gap exists in the literature regarding the relationship between childhood adversity and romantic relationships among older adults. The purpose of this study was to examine the relationship between childhood violence exposure and later-life romantic relationships; this included assessing relationship happiness, partner reliance, relational functioning, and communication among partnered older a …

02.09.2026journal-article

The Learning Organization

Extending the people-process-technology triade in knowledge management: a cognitive perspective on multilevel knowledge flow

Hala Sibari, Asmae Houmid Bennani

Purpose This paper aims to reconceptualize knowledge management (KM) tools by integrating sociotechnical systems theory with insights from cognitive psychology. Design/methodology/approach This conceptual paper is grounded in a Critical Interpretive Synthesis (CIS) of an analytical corpus of 85 peer-reviewed studies retrieved from Scopus and Web of Science (documented through a preferred reporting items for systematic reviews and meta-analyses-inspired flow diagram), complemented by 54 theoretical and contextual so …

02.09.2026journal-article

Journal of Surgical Oncology

Morbidity and Mortality of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in Patients Aged 70 Years and Older: A Two‐Center 10‐Year Experience

Ali Ediz Kıvanç, Mehmet Oduncu, Pırıltı Özcan, Özgül Düzgün, Neşet Köksal

ABSTRACT Background and Objectives Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is established for peritoneal surface malignancies, but its use in older patients is debated. We assessed CRS‐HIPEC morbidity and mortality in patients aged ≥ 70 years using a cohort of younger patients as a comparator. Methods We retrospectively reviewed consecutive patients aged ≥ 70 and

02.09.2026journal-article

Diabetology

Baseline Eating Behaviors and Responsiveness to TelePhysio in Older Patients with Type 2 Diabetes: An Exploratory Secondary Analysis of the TelePhysioT2D Trial

Hiroaki Kataoka, Takuo Nomura, Hiroyuki Oka, Yukio Ikeda

Background/Objectives: Telerehabilitation for physiotherapy programs (TelePhysio) has been shown to improve knee extension force (KEF) in older patients with type 2 diabetes mellitus (T2DM), but factors associated with responsiveness remain unclear. This exploratory secondary analysis investigated whether baseline eating behaviors modified the effectiveness of TelePhysio in KEF. Methods: This secondary analysis included 74 older patients with T2DM enrolled in a randomized controlled trial. The participants were ass …

02.09.2026journal-article

KVM Research Journal

Electronic Financial Capabilities Influence on Investment Decision of People: DataDriven from Nepal

Rajesh Singh Bist

This Article analyze the influence on investment decision of people made by modern electronic financial literacy within socio-economic areas of Nepal. 358 respondents were surveyed for this research work. Comparative research design was applied in shaping investment decision by electronic literacy. For statistical task, appropriate sampling was used to collect wide range of viewpoint. The response of respondent collected by providing simple questionnaire through multiple networks. Participants privacy and identity …

02.09.2026journal-article

Asia Pacific Economic and Management Review

Impact of Medical Insurance Type on Healthcare Utilization among Older Adults: An Empirical Analysis Based on CHARLS Data

Jiani Chen

Using 2018 CHARLS data, this study examines how medical insurance types affect healthcare utilization among older adults through Logit and negative binomial regression models, along with heterogeneity and robustness tests. The results show a structural interaction between basic and commercial health insurance: commercial insurance promotes outpatient care for Urban Employee Basic Medical Insurance (UEBMI) enrollees but encourages inpatient care for Urban and Rural Resident Basic Medical Insurance (URRBMI) enrollees …

02.09.2026journal-article

Humanities and Social Sciences. Bulletin of the Financial University

The Impact of Volunteer Work on the Development of Professional Skills and Career Aspirations of Young People

A. V. Bredikhin, D. A. Trofimov

This article analyzes the impact of volunteerism on the development of professional competencies and the career trajectory of today’s youth. Using an interdisciplinary approach, this paper explores the theoretical aspects of volunteering as an informal educational institution, the functional mechanisms for transferring soft skills to the professional environment, and the correlation between volunteer experience and the career aspirations of university and college graduates. Particular attention is paid to the parad …

02.09.2026journal-article

Healthcare

Turkish Cross-Cultural Adaptation of the BRIEF-MPI in Older Adults with Cancer: Convergent and Discriminative Validity Compared with the G8 and Clinical Frailty Scale

Sercan On, Haydar Cagatay Yuksel, Semih Sergen Semerci, Ecem Ozdemir, Mustafa Kagan Ozdel, Fatma Ozge Kayhan Kocak

Background: Older adults with cancer represent a heterogeneous population with varying levels of frailty and multidimensional vulnerability. Rapid screening tools are needed to identify patients who may benefit from comprehensive geriatric assessment (CGA). This study aimed to translate and culturally adapt the Brief Multidimensional Prognostic Index (BRIEF-MPI) into Turkish and evaluate its performance in older adults with cancer. Methods: This cross-sectional methodological study included 177 patients aged ≥65 ye …

02.09.2026journal-article

Metallurgical and Materials Transactions A

Dynamic Strain Aging in Single Crystal Vanadium: Material Characterization and Dislocation-Based Crystal Plasticity Framework

Thao Nguyen, Saryu J. Fensin, James A. Valdez, Lauren J. Beesley, Darby J. Luscher, John S. Carpenter

Abstract In this study, we investigate the mechanical behavior of single-crystal vanadium and introduce an enhanced dislocation-based crystal plasticity framework to model its response under various loading conditions. Our experiments, conducted over a wide range of temperatures and strain rates on single-crystal vanadium samples, reveal progressive thermal hardening at low strain rates and elevated temperatures. This behavior is indicative of dynamic strain aging (DSA), a phenomenon previously observed in polycrys …

02.09.2026journal-article

Current Opinion in Nephrology & Hypertension

Displaced people and kidney health

Sanjib Kumar Sharma, Urza Bhattarai, Arun Gautam

Purpose of review The number of displaced people worldwide continues to rise because of conflict and disasters-related crises. Kidney disease is increasingly recognized as an important contributor to morbidity among displaced populations, yet it remains under-prioritized in humanitarian responses. This review summarizes current evidence on the burden, risk factors, barriers, and management of kidney disease in displaced settings. Recent findings Recent literature highlights multiple risk factors linking displacemen …

02.09.2026journal-article

Orthopaedic Surgery

Global Alignment and Proportion ( GAP ) Score in Predicting Mechanical Complications After Long‐Segment Fixation for Chinese Geriatric Patients With Adult Degenerative Scoliosis: A Mid‐Term Comparative Study

Xiangyao Sun, Jiang Huang, Yuqi Liu, Siyuan Sun, Li Cao, Juyong Wang, Shibao Lu

ABSTRACT Objectives The predictive value of the global alignment and proportion (GAP) score in the Chinese geriatric population, which has unique demographic and degenerative characteristics, has not been validated. Given the high incidence of mechanical complications in this specific cohort, a dedicated mid‐term evaluation is essential to guide surgical planning. To address this gap, this study aimed to analyze the accuracy and characteristics of the GAP assessment system in predicting mechanical complications fol …

02.09.2026journal-article

Journal of Autism and Developmental Disorders

The Transition to Mental Health Services From the Perspectives of Neurodivergent Young People, Caregivers and Mental Health Professionals: A Constructivist Grounded Theory Approach

Kim Tang, Robert Wells, Craig Thompson, Elizabeth Hill, Elizabeth Pellicano, Bronwyn Myers

Abstract Purpose The prevalence of mental health conditions is increasing globally, with mental health difficulties the leading cause of disability for young people aged 12 to 25 years. Neurodivergent young people are up to three times more likely to develop a co-occurring mental health condition, requiring formal support from childhood to adulthood. They also experience delayed access to adult mental health care once they have been discharged from child mental health services. This study aimed to investigate what …

02.09.2026journal-article

Cells

The Paradox of Tau and RNA-Binding Proteins: How Adaptive Stress Granule Regulation Becomes Pathological with Aging

Benjamin Wolozin, Merci Best, Madhav Ellini, Yuran Ma, Sojung Bok, Dylan Hwang, Carolina Filipponi

RNA-binding proteins (RBPs) are a large class of proteins that form biological condensates to facilitate their functions. Chronic stress, such as occurs in neurodegenerative diseases, stimulates persistent accumulation of particular RBP condensates as part of the translational stress response, termed stress granules (SGs). These persistent SGs serve as a nidus for aggregation of RBPs to form pathologies that appear in neurodegenerative diseases, such as the occurrence of Tar DNA Binding Protein (TDP-43) in Amyotrop …

02.09.2026journal-article

Alternative Law Journal

Fare evasion by young people in New South Wales: Time to decriminalise?

Julia Quilter, Grace Bowles

Fines for fare evasion are the most commonly issued penalties to young people in New South Wales (NSW). Public transport is fundamental to a young person’s growing independence as well as to access education, employment and maintain social ties. This article reports on high volumes of fines issued to young people up to the age of 25 for fare evasion in NSW and patterns of fine issuance by police and transit officers. Too many young people are still punished for their inability to pay for fares. We advocate for refo …

02.09.2026journal-article

Nature Aging

Reframing the epidemiological transition as increasing returns to tackling aging-related diseases

Julian Ashwin, David E. Bloom, Naomi Lee, Peter Piot, Andrew J. Scott

Abstract Global life expectancy has risen since 1973 from 58 to over 73 years, while the share of people aged 65 years and older has doubled to 10% and is projected to reach 21% by 2073. This shift is linked to an epidemiological transition from infectious to chronic disease. Here, using Global Burden of Disease data, we reframe this transition by statistically grouping diseases on the basis of their impact over the life cycle, yielding four clusters: infant, early-adult, later-adult and aging-related. We show agin …

02.09.2026journal-article

Polymer Engineering & Science

In Situ FTIR Analysis of Bond‐Scale Degradation Behaviors in HTPB Elastomers Under Multi‐Field Coupled Aging

Xiaoru Wang, Guoxuan Ma, Li Zhou, Lipeng Sang, Shuang Li, Jianru Wang, Bo Yuan, Xueren Wang, Chunxiang Li

ABSTRACT Changes in chemical bonds driven by combined thermo‐oxidative aging and mechanical loading directly influence the structural integrity of hydroxyl‐terminated polybutadiene (HTPB) propellants. Due to uncertainties surrounding the chain scission mechanism of HTPB subjected to thermo‐oxidative aging, and the confounding effects of concomitant cross‐linking and chain scission on experimental measurements and data interpretation, the present work identifies urethane cross‐links as characteristic recognition sit …