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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
02.09.2026journal-article

International Journal of Clinical Pharmacy

Evaluation of clinical interventions made by pharmacists, doctors and nurses in a hospital post-discharge telephone service: a retrospective cohort study

Kum Chuan Leong, Darshana Meanger, Philip Wu, Alex Wong, Wee Tjun Tee, Michelle Simango, Bianca Levkovich

Abstract Introduction Clinician-led post-discharge telephone follow-up programs are effective in resolving medication-related problems (MRPs) in older adults. Our hospital offers a post-discharge telephone service, Talk-To-You-Tomorrow (TTYT), to general medicine patients to support medication management following hospital discharge. However, little is known about the the types of interventions used to address MRPs between clinicians within post-discharge telephone services. Aim To compare the types of intervention …

02.09.2026journal-article

PLOS One

Plasma levels of antimicrobial peptide LL-37 as a biomarker of sleep quality in patients with obstructive sleep apnea: A clinical observational study

Takayuki Yamaguchi, Keisuke Hosokawa, Takenori Mineta, Rie Hosokawa, Shiho Odawara, Rie Chiba, Kazue Asanuma, Setsuko Toyomaki, Mitsuho Sato, Fumiaki Takahashi, Shigeru Sakurai, Kazuhiro Takahashi, Tsuguo Nishijima

Objectives Obstructive sleep apnea (OSA) is characterized by systemic inflammation, intermittent hypoxemia, and immune dysregulation and has been associated with increased susceptibility to viral infections. In this study, we aimed to evaluate plasma concentrations of the antimicrobial peptide cathelicidin LL-37 (pLL-37) in individuals with OSA. Methods The associations between pLL-37 levels, demographic characteristics, and polysomnographic (PSG) parameters were assessed in 58 individuals with OSA and 20 healthy c …

02.09.2026journal-article

Emergency Medicine Journal

Initial treatment of presumed pacemaker or implantable cardioverter defibrillator malfunctions: algorithm and rationale

Matthias Mueller, Christoph Weiser, Michael Pfeffer, Thomas Mitteregger

The increasing prevalence of permanent pacemakers (PPMs) and implantable cardioverter defibrillators (ICDs) has led to a rising number of device malfunctions, which can have painful or even life-threatening consequences. As device technology advances, emergency personnel frequently face uncertainty in the initial management of these complex patients, given limited access to device reprogramming or interrogation outside specialised cardiology settings. This paper presents practical algorithm-based approaches for the …

02.09.2026journal-article

npj Antimicrobials and Resistance

Treatment of Herpes simplex encephalitis with the helicase-primase inhibitor pritelivir in an immunocompromised patient

Catherina Lueck, Christina Rautenberg, Alexander Birkmann, Susanne Bonsmann, Alessandra Marini, Melanie Sumner, Thomas Schroeder, Sebastian Voigt

Abstract Pritelivir, a novel helicase-primase inhibitor, has successfully completed a global Phase 3 trial for refractory herpes simplex virus (HSV) infections in immunocompromised patients. This case report is the first clinical use of pritelivir in Herpes simplex encephalitis (HSE). An allogeneic hematopoietic cell transplant recipient developed HSE and was treated with acyclovir. After 1.5 months, while still on valacyclovir prophylaxis, HSE relapsed, confirmed by Magnetic Resonance Imaging (MRI) and HSV1 DNA de …

02.09.2026journal-article

Journal of Neonatal-Perinatal Medicine

Understanding and addressing bias in neonatal drug screening practices

Megan Kalata, Alexandra Van Cleave, Lillian Eason, Mary Kate Eiden, Amrita Purkayastha, Sun Young Guwn, Meghan Fries, Lauren Seger, Emily Callahan

Background Urine drug screening (UDS) is commonly utilized to identify substance use during pregnancy and facilitate timely interventions aimed at mitigating adverse parental and neonatal outcomes. Current literature has demonstrated that UDS among pregnant patients is not uniformly applied across populations but less is known about screening practices among neonates. This study aimed to evaluate the demographics, clinical indications, documentation and disclosure practices, and outcomes associated with neonatal dr …

02.09.2026journal-article

Perspectives of the ASHA Special Interest Groups

Ghanaian Speech-Language Pathologists and Stuttering Treatment: Changes in Knowledge and Confidence After Professional Development

Emmanuel Kwaku Addo, Rodney Gabel, Stephanie Lebsack

Purpose: Speech-language pathologists (SLPs) worldwide face challenges in treating people who stutter, often citing inadequate knowledge and confidence, particularly in assessment and intervention. This study explored the strengths and areas of need among Ghanaian SLPs in treating stuttering. A secondary aim examined changes in SLPs' self-rated knowledge and confidence levels before and after a 6-week asynchronous online stuttering professional development (PD) program. Method: A secondary data set comprising 34 re …

02.09.2026journal-article

Jurnal Kebidanan dan Kesehatan Tradisional

The Effect of THM (Traditional Herbal Medicine) On Reducing Blood Sugar Levels in Type 2 Diabetes Mellitus Patients in Indonesia: A Sytematic Review and Meta-Analysis

Ardini Syahrini, Arrafi Insani

Background: Diabetes is a global health issue that currently receives widespread attention. Indonesia, a tropical archipelagic nation and a hotspot for biodiversity, offers a rich array of natural resources, making the use of herbal plants or traditional medicine a popular treatment option among the public. This study aims to conduct a systematic review and meta-analysis regarding the effect of THM (traditional herbal medicine) on blood sugar reduction in patients with type 2 diabetes. Methods: This study aims to c …

02.09.2026journal-article

Journal of Small Animal Practice

Clinical findings and outcomes of juvenile‐onset chronic kidney disease of unknown aetiology in dogs: a retrospective study of 36 cases (2010‐2023)

H. Miyakawa, M. Nakano, M. Ishizaka, A. Miyagawa, Y. Miyagawa, N. Takemura

Objectives To describe the clinical findings and outcomes of juvenile‐onset chronic kidney disease of unknown aetiology in dogs. Materials and Methods This retrospective study included 36 client‐owned dogs under 3 years of age with chronic kidney disease. In the observational cohort study, the signalment and clinicopathology findings in the dogs ( n = 36) were described. A longitudinal analysis ( n = 28) was performed to investigate the time to chronic kidney disease progression and death. The risk of chronic kidne …

02.09.2026journal-article

Pharmacia

Post-treatment serum interleukin-6 is independently associated with disease progression in patients with advanced non-small cell lung cancer and coexisting COPD: a multicenter real-world cohort study

Akram Hasan Kareem, Samer Imad Mohammed, Ahmed Abdali Shihad

An observational multicenter cohort study involving 120 patients treated with chemotherapy alone or in combination with pembrolizumab or atezolizumab was conducted. Interleukin-6 (IL-6) levels were measured after six cycles, and response of tumor was estimated with the Response Evaluation Criteria in Solid Tumors (RECIST). Receiver operating characteristic (ROC) analysis was conducted. IL-6 levels were significantly reduced in the chemo-immunotherapy groups compared with the chemotherapy group ( p < 0.001). Patient …

02.09.2026journal-article

Frontiers in Bioengineering and Biotechnology

A breath of fresh air: the role of oxygen carriers in plastic surgery

Leon Guggenheim, Valeria Pruzzo, Francesca Bonomi, Ettore Limido, Andrea Weinzierl, Matthias W. Laschke, Yves Harder

Tissue hypoxia represents a major challenge in regenerative medicine because it may impair wound healing and contribute to tissue necrosis and eventually reconstructive failure. To overcome this problem, topically applied oxygen carriers have emerged as a promising strategy to enhance tissue oxygenation independently of vascular function. This narrative review summarizes the clinical evidence for the use of oxygen carriers in plastic, reconstructive and aesthetic surgery. Four principal categories were identified, …

02.09.2026journal-article

Journal of Clinical Medicine

Group 3 Pulmonary Hypertension: Mechanistic Insights, Clinical Challenges, and Evolving Therapies

Steven C. Liu, Madeline Ku, Priyanka Mohnani, Tanvi Borse, Bharat Bajantri

Group 3 pulmonary hypertension is a common and clinically significant complication of chronic lung disease and hypoxia that is associated with impaired functional capacity, right ventricular dysfunction, and increased mortality. Historically viewed as a consequence of underlying parenchymal lung disease, Group 3 pulmonary hypertension is now recognized as a complex disorder involving pulmonary vascular remodeling, dysregulated molecular signaling, and maladaptive cardiopulmonary interactions. Advances in translatio …

02.09.2026journal-article

Problems of Gathering Treatment and Transportation of Oil and Oil Products

EXPERIENCE WITH THE USE OF A SCALE I NHIBITOR IN HIGHLY CONCENTRATED AND ULTRA-CONCENTRATED BRINES

A.M. Kunakova

The problem of scale deposition becomes even more pressing in oilfields whose formation waters are classified as concentrated and highly concentrated brines. The salinity of such waters ranges from 100 to 500 g/L. The aim of this work is to systematize and critically review the experience of using scale inhibitors in oilfields of the Russian Federation and neighboring countries. The study is based on a comparative analytical review of scientific literature and patent documentation published between 2005 and 2025. I …

02.09.2026journal-article

Clinical Kidney Journal

Treating depression in dialysis patients: pharmacological and non-pharmacological approaches

Daniel Cukor, Christian Cornelius, Kate Dahl, Daniela Figueiredo, Helena Sousa, Ava Archey, Paul L Kimmel

Abstract Depression is relatively common in patients with kidney failure treated with hemodialysis, and the prevalence rate exceeds that of the general population. Depression should be treated in people maintained on dialysis, both due to depression’s inherent significance and its potential complications for kidney treatment. This paper reviews the relevant literature on reported pharmacological and non-pharmacological approaches. Although the evidence base is somewhat limited, recent clinical trials have allowed f …

02.09.2026journal-article

Molecular Psychiatry

Neurophysiological signatures of Stanford Neuromodulation Therapy in treatment resistant depression

Davide Momi, Derrick M. Buchanan, Masataka Wada, Andrew D. Geoly, Noriah J. Johnson, Eleanor J. Cole, Adi Maron-Katz, Claudia Tischler, Christopher C. Cline, Diego A. Pizzagalli, Manish Saggar, Daphne Voineskos, John D. Griffiths, Camarin E. Rolle, Corey J. Keller, Nolan Williams

Abstract Treatment-resistant depression (TRD) affects approximately 30% of patients with major depressive disorder. Stanford Neuromodulation Therapy (SNT), a high-dose intermittent theta-burst transcranial magnetic stimulation protocol, produces rapid antidepressant effects, but its neurophysiological mechanisms remain unclear. Here, we used longitudinal TMS-EEG to characterize the progressive neurophysiological changes induced by SNT, assess their site-specificity, and explore whether baseline neural markers are a …

02.09.2026journal-article

BMC Oral Health

Clinical and radiographic evaluation of autologous sticky bone versus PRF with OCP-coated deproteinized bovine bone graft in periodontal infrabony defect regeneration: a randomized controlled trial

Sakshi V. Kotecha, Priyanka Jaiswal, Shweta Bhagat, Pranjal Laturiya, Geeta Bhandari

Abstract Background Periodontal therapy aims to regenerate the attachment apparatus, including alveolar bone, periodontal ligament, and cementum. Infrabony defects are linked with periodontal progression if left untreated. To address limitations of conventional regenerative materials, Autologous Sticky Bone was developed, while Octacalcium Phosphate–Deproteinized Bovine Bone Material (OCP-DBBM) offers favorable conditions for capillary and osteogenic cell ingrowth. Methods Since comparative evidence is limited, thi …

02.09.2026journal-article

Acta Odontologica Turcica

Awareness and Clinical Practices on Implant Abutment Cleaning in Türkiye

Habibe Öztürk Ulusoy, Rüveyda İrem Şentürk, Süeda Kılıç, Şafak Çiçek

OBJECTIVE: There is no standard protocol for abutment cleaning before the final abutment–implant connection to minimize contamination-related risks that can be applied in the clinic. This research aims to determine whether Turkish dentists use any cleaning, disinfection, and/or sterilization procedures before connecting customized abutments to the implant and, if so, which procedures they apply. METHODS: This study was conducted between 15.12.2022 and 15.06.2023. A link to the survey consisting of four questions wa …

02.09.2026journal-article

Journal of Sustainable Mining

Microwave thermal pre-treatment to improve nickel extraction from lateritic ore

Johana Borda, Daniel Sosa, Robinson Torres

Two heat treatment processes for a nickeliferous laterite sample are presented, one by the conventional muffle route and the other by microwave. The heating was carried out in order to improve the dissolution of nickel in an acid medium. The study describes the changes observed in the mineral for the increase in temperature as a consequence of radiation in the microwave and in the muffle. The changes in the mineral crystalline phases were analyzed by X-ray diffraction. The leaching media consisted of a 1 M sulfuric …

02.09.2026journal-article

The Journal of Aging and Social Change

“Outside We May Become Wrinkly but Inside We Are Growing Crumbly”

Liana Winett, Louise Dalingwater

Women’s health in both the United States and the United Kingdom lags that of men in clinical understanding, options, and access. Even some phenomena that exclusively affect women and which represent a near-universal experience, such as menopause, have historically received less attention than their ubiquity might suggest. Given that the governments of both nations have material influence over how health is perceived and addressed, we wished to explore whether and how menopause has been perceived as a national polic …

02.09.2026journal-article

Ophthalmic Plastic & Reconstructive Surgery

WSOPRAS and ITEDS Consensus Statement on the Assessment and Management of Thyroid Eye Disease

Andrea L. Kossler, Ashok K. Grover, Antonio A.V. Cruz, Lelio Baldeschi, Michael Kazim, Timothy J. Sullivan

Purpose: To develop a globally applicable consensus statement for the assessment and management of thyroid eye disease (TED). Methods: The World Society of Ophthalmic Plastic Reconstructive and Aesthetic Surgery council selected a 6-member, geographically diverse TED task force to develop a consensus statement on the assessment and management of TED. Consensus was achieved through monthly meetings from January to July 2025, alongside an analysis of the literature in terms of relevance, level of evidence, and global …

02.09.2026journal-article

Annals of Plastic Surgery

Proximal-First Pedicle Approach for Prone Latissimus Dorsi Flap Harvest: Technical Refinement for Posterior Reconstruction

Yooseok Ha, Jeong Tae Kim, Seung Eun Hong, Youn Hwan Kim

Background: Reconstruction of posterior body defects often requires intraoperative repositioning, which increases operative time and disrupts surgical workflow. Although the latissimus dorsi (LD) flap is a reliable option for posterior reconstruction, prone-position LD harvest has been infrequently described outside of breast reconstruction. This study introduces a proximal-first pedicle approach for LD flap harvest in the prone position and evaluates its clinical applicability for posterior body reconstruction. Pa …

02.09.2026journal-article

International Journal of Innovative Technologies in Social Science

PHYSICAL ACTIVITY IN DEPRESSION MANAGEMENT: MECHANISMS, CLINICAL IMPLICATIONS, AND EXERCISE PRESCRIPTION - A NARRATIVE REVIEW

Katarzyna Zegadło, Katarzyna Jolanta Kuc, Maciej Dobrucki, Krzysztof Brzezicki, Patryk Jakubiak, Aleksandra Cieciora, Mateusz Cieciora, Małgorzata Kawiorska, Julia Surowiec, Wiktoria Ruta Bełcikowska-Skowron

Background: Depression is one of the top contributors to global disability and represents an important public health challenge. Studies show an increasing body of evidence that physical activity might be instrumental in both the prevention of and intervention with depressive disorders. Purpose of the investigation: This narrative review intends to summarize and synthesize current evidence pertaining to the antidepressant effects of physical activity, considering suggested mechanisms, clinical results, and prescript …

02.09.2026journal-article

PLOS One

Technology-Assisted Rehabilitation Gym for at-home Training (TARGeT) for stroke survivors: A study protocol for evaluating feasibility, safety, usability, clinical benefit, and costs

Simone Kager, Hsiao-Ju Cheng, Christopher Wee Keong Kuah, Tengiz Samkharadze, Hao Ping Lin, Chwee Yin Ng, Tegan Kate Plunkett, Sam Lee, Niranjana Devi, Filzah Sumartono, Isaac Lu, Ananda Sidarta, Eloise Lie, Irina Hungerbuehler, Daryl Chong, Anoop Kumar Sinha, Chi Onn Tang, David Matchar, Giada Devittori, Christoph Kanzler, Asif Hussain, Bernardo Noronha, Muhammad Azhar, Gabriel Aguirre-Ollinger, Roger Gassert, Karen Sui Geok Chua, Nicole Wenderoth, Olivier Lambercy

Stroke is a leading cause of long-term disability, with more than half of survivors experiencing persistent upper limb impairments. Despite clear evidence that high-dose, repetitive, task-specific training is essential for motor recovery, many stroke survivors do not receive a sufficiently high therapy dose – particularly in the outpatient phase. Limited therapist availability, high care costs, and travel burdens remain key barriers to accessing rehabilitation training. While technology-assisted rehabilitation has …

02.09.2026journal-article

Dental Nursing

Supporting patients through jaw surgery

Ibrahim Rana

Ibrahim Rana explores the dental nurse's role in the orthognathic surgery pathway. Aim: To provide dental nurses with an overview of the orthognathic surgery pathway, with a focus on their clinical responsibilities at each stage of treatment. Objectives: To define the clinical stages of the orthognathic pathway, from initial assessment through to post-treatment retention. To outline the responsibilities of the dental nurse within the multidisciplinary team at each stage of the orthognathic pathway. To reflect on co …

02.09.2026journal-article

Aesthetic Surgery Journal Open Forum

Temporal Histological Tissue Responses Following Fractional Non-Ablative 1470 nm Laser Exposure: A Pilot In Vivo Human Study

Paweł Kubik, Wojciech Gruszczyński, Aleksandra Pawłowska, Maciej Malinowski, Maria-Luiza Piesiaków, Brygida Baran, Agnieszka Pawłowska-Kubik, Łukasz Kodłubański, Dariusz Grzanka, Paulina Antosik, Bartłomiej Łukasik

Abstract Background Fractional non-ablative lasers enable controlled dermal heating while preserving epidermal integrity. The 1470 nm wavelength shows strong water absorption and moderate penetration, but in vivo human histological data on early tissue responses remain limited. Objectives To characterize early, time-dependent histological responses and assess short-term histologic tolerability of a fractional 1470 nm laser (LaserMe). Methods Eighteen healthy adults were enrolled and allocated to six treatment group …