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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
31.08.2026journal-article

ANNALS OF ABBASI SHAHEED HOSPITAL AND KARACHI MEDICAL & DENTAL COLLEGE

Cone Beam Computed Tomography in Oral Cancer: A Review of Bone Invasion Radiomics, and Artificial Intelligence

Bahaa Aldeen Hadi, Hussein Kadhim

Cone beam computed tomography (CBCT) is prevalent in maxillofacial imaging due to its high-resolution bone detail and quick, chairside operation that generally exceeds conventional CT in radiation dose efficiency. However, recent clinical claims about its effectiveness in oral squamous cell carcinoma (OSCC) are not fully supported by physics. Current verified literature (up to June 2026) clarifies that CBCT should be reserved for secondary purposes like bone invasion evaluation, surgical planning, and radiotherapy, …

31.08.2026journal-article

International Journal for Research in Applied Science and Engineering Technology

Evaluation of Complete Blood Count (CBC) among patients with Breast, Ovarian and Colon Cancer Patients Before and After Chemotherapy Administration at Shendi Oncology Center, Sudan- 2026

Wala Eldin Osman Elradi, Aisha A. S. Abdallatif, Alaa B. M. Abdrhman, Alaa G B Ibrahim, Ibtisam K. A. Anwar, Omer F A. Mohammed, Maab Shames AL-deen G. A, May A. M. Ashmaig

Background: Chemotherapy administrated to cancer patients as it toxic and aiming to confine cancer spread for normal organs has effects, it observed that changes in hematological parameters during anti-cancer drugs differ before starting treatment. To this study aimed to evaluate changes may occur among 3 different cancers’ patients attended to Shendi Oncology center- River Nile State. Method: The study was approved by Sudan International University-hospital administration as well as patients as they already consen …

31.08.2026journal-article

Gazi Sağlık Bilimleri Dergisi

CONCURRENT BLADDER TUMOR AND HERNIATION OF THE URINARY BLADDER INTO THE SCROTUM: CASE REPORT

Deniz Hoto, Şafak Ulutürk, Almira Gürcan

Bladder tumors rank second among urinary system cancers and fourth among the most common cancers in men. Bladder hernias constitute a small proportion (1–3%) of all hernias, and only a much smaller fraction of these are associated with bladder tumors. In treatment, the tumor is surgically excised and hernia repair is performed. In this case report, a 64-year-old male patient who presented to the general surgery outpatient clinic with complaints of inguinal swelling, pollakiuria, hematuria, and nocturia was evaluate …

31.08.2026journal-article

Endocrine Oncology

Current Evidence Across the Treatment Spectrum of Adrenocortical Carcinoma: A Comprehensive Scoping Review

Angélica María González-Clavijo, Luis F. Fierro-Maya, Diego F. Ballen, Deyanira González-Devia, Andrés Arturo Cuéllar-Cuéllar, Mauricio García-Mora, Diego M. González-Ramírez, Mireya Tapiero García, Alejandro Román-González, Marino Cabrera, Jesús O. Sánchez-Castillo, Sara Correa-Giraldo, Carlos E. Builes-Montaño

Abstract Adrenocortical carcinoma is a rare and aggressive malignancy for which high-quality evidence to guide clinical decision-making remains limited. This scoping review aimed to map and synthesise the extent, nature, and direction of evidence across five therapeutic domains in the management of adrenocortical carcinoma. Following Joanna Briggs Institute methodology and Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews guidance, MEDLINE, Embase, and the Cochrane Lib …

31.08.2026journal-article

Cancer Reports

Timeliness of Colorectal Cancer Care in Veterans: The Role of Travel Distance

Emma M. Bradley, Megan Shroder, Gretchen Edwards, Shannon McChesney, Colleen Kiernan, Robert S. Dittus, Christianne L. Roumie

ABSTRACT Background Rural patients experience healthcare disparities due to multiple factors including travel distance. However, the impact on colorectal cancer (CRC) care for Veterans remains undefined. Aims We aimed to describe the association between distance and timeliness of care for Veterans with CRC. Methods and Results We assembled a retrospective cohort of Veterans with Stage I–III CRC who underwent resection at a Veterans Affairs Medical Center (VAMC) between 2001 and 2018. Time from diagnosis to initiati …

31.08.2026journal-article

Clinical and Experimental Medicine

Cancer-associated fusion transcripts: mechanisms, functional roles, and clinical implications

Md Faruq Hossain

Abstract Fusion transcripts are hybrid RNA molecules generated through genomic rearrangements or RNA-level fusion mechanisms. They represent important molecular features of many cancers and can function as oncogenic drivers, diagnostic biomarkers, prognostic indicators, and therapeutic targets. Since the discovery of the BCR::ABL1 fusion in chronic myeloid leukemia, numerous cancer-associated fusion transcripts have been identified across hematologic malignancies and solid tumors. These fusion events encompass dive …

31.08.2026journal-article

Pathology & Oncology Research

Impact of p53 status on recurrence patterns and oncologic outcomes in non-invasive high-grade endometrial cancer

Eduardo Paulino, Thiago Branco, Guilherme Gomes de Mesquita, Andreia Cristina de Melo

Objective This retrospective study evaluated the impact of p53-abnormal (p53abn) status on recurrence patterns and outcomes among patients with non-invasive, high-grade endometrial cancer (EC) treated at the Brazilian National Cancer Institute (INCA) between 2010 and 2025. Methods Eligible patients had high-grade histologies—including endometrioid grade 3 (ECG3), serous (USC), clear cell (CC), carcinosarcoma (CS), mixed, or undifferentiated tumors—without myometrial invasion. Clinical, surgical, and pathological ch …

31.08.2026journal-article

Ophthalmologica Indonesiana

The Hidden Costs of Inpatient Glaucoma Treatment: Out-of-Pocket Burden at a Tertiary Care Hospital in Yogyakarta

Sang Ayu Putu Udara Pradnyadewi, Krisna Dwi Purnomo Jati, Meta Rahma An Nazzila, Tatang Talka Gani

Introduction and Objective: Glaucoma requires lifelong care, generating out-of-pocket (OOP) costs despite insurance coverage. This study assessed OOP expenditure among hospitalized glaucoma patients covered by Indonesia’s National Health Insurance (JKN). Methods: A hospital-based cross-sectional study included 40 purposively selected glaucoma inpatients from December 2024 to February 2025. Self-reported data were collected through structured interviews. Multiple linear regression examined associations between socio …

31.08.2026journal-article

Cancer Reports

Survival and Mortality Predictors in Prostate Cancer: A Retrospective Cohort of 10 556 Brazilian Patients

Wesley Rocha Grippa, Larissa Soares Dell'Antonio, Cristiano Soares Dell'Antônio, Luciane Bresciani Salaroli, Luís Carlos Lopes‐Júnior

ABSTRACT Background Prostate cancer (PCa) remains one of the most frequently diagnosed malignancies worldwide and represents a major contributor to premature mortality among men. This study aimed to estimate survival and investigate factors associated with PCa‐specific mortality among men treated within the oncology care network of a Brazilian state. Material and Methods Retrospective cohort study was conducted using data obtained from hospital‐based cancer registries linked to the state Mortality Information Syste …

31.08.2026journal-article

International Journal Of Community Medicine And Public Health

Can AI see what the surgeons see? Analyzing the accuracy of ChatGPT: publicly available multimodal AI for radiographic interpretation and treatment plan in oral surgery

Astha A. Jathar, Varsha S. Manekar, Akash M. Bakale, Komal Rewatkar, Ayush A. Jathar

Background: With the rise of AI, patients have been actively doing their own research. With emergence of easily accessible multimodal AI, such as ChatGPT-5 that can interpret images, there is a growing need to evaluate their accuracy, reliability, and potential clinical application. Therefore, this study aimed to evaluate the accuracy of radiographic diagnostics and surgical treatment planning of ChatGPT-5 in the context of oral and maxillofacial surgery. Methods: We conducted a cross-sectional study using ChatGPT- …

31.08.2026journal-article

International Journal Of Community Medicine And Public Health

Knowledge, attitude, practices and awareness of cervical cancer among female medical students at Faculty of Indigenous Medicine, University of Colombo: a cross-sectional study

Gunaseelan Savithri Sanjeewani, Mohammed Umar Ziard Noorul Farzana, Hasan Ali Afeefa Masha

Background: Cervical cancer, major health problem particularly in South Asia. While it is preventable via vaccination and screening, even were knowledge and practice gaps, among future health care providers. Study aimed to determine the knowledge, attitude, practice and awareness (KAP) regarding cervical cancer among the female medical students at faculty of indigenous medicine (FIM), University of Colombo (UoC). Methods: A descriptive cross-sectional study was conducted among 100 indigenous medical students at Fac …

31.08.2026journal-article

Drugs in Context

How to manage medullary thyroid carcinoma: current treatment strategies

Katerina Saltiki, Olga Karapanou, Marina Michalaki, Grigoris Effraimidis

Medullary thyroid carcinoma (MTC) is a rare thyroid malignancy, representing approximately 2–5% of all thyroid cancers. It develops from the parafollicular C cells of the thyroid gland. Calcitonin, produced by parafollicular C cells, is a highly reliable biomarker for both diagnosis and disease monitoring. MTC commonly spreads to cervical lymph nodes and can also lead to distant metastases. Approximately 25% of MTC cases are hereditary, occurring as part of multiple endocrine neoplasia syndromes. Inherited forms ar …

31.08.2026journal-article

Artefactum - revista de estudos interdisciplinares

WOMEN'S HEALTH CARE IN THE FAMILY HEALTH PROGRAM: PRE-PROFESSIONAL EXPERIENCE WITH AN EMPHASIS ON CERVICAL CANCER PREVENTION

Rosane Seeger da Silva, Seomara Espindola Weissheimer, Sabrina Hardt Torri, Débora Einloft, Maria Rozane Campanholo Coelho, Jodete Medianeira Niederauer Brasil, Roselaine Pinheiro Antunes

This study, conducted as a course completion project, aims to highlight the importance of administrative and care-related nursing activities within Family Health Program (PSF) units in a municipality in the interior of Rio Grande do Sul. It seeks to develop nursing competencies regarding women's health—specifically concerning cervical cancer—and to address health education issues by devising health promotion strategies tailored to the local context of this population. The methodology involved carrying out practical …

31.08.2026journal-article

Current Cancer Drug Targets

MicroRNAs and Their Crosstalk with Oncogenic Pathways in Gastric Cancer

Liushan Wei, Jia Yu, Yan Hu, Shijie Wu, Yuhui Feng, Shengsong Tang, Guiqin Li, Yuxuan Liang, Xiaoyong Lei, Xiaoyan Yang

Abstract: Gastric Cancer (GC) is the fifth most frequently diagnosed malignancy and the third leading cause of cancer-related mortality worldwide. The aggressive nature of GC, coupled with late clinical presentation and limited therapeutic options, underscores the urgent need for a deeper molecular understanding of its pathogenesis. In the past, microRNAs (miRNAs)—evolutionarily conserved, 19-25-nucleotide, non-protein-coding RNAs—have emerged as pivotal post- transcriptional regulators that simultaneously modulate …

03.09.2026journal-article

Journal of Surgical Case Reports

Spinal epidural calcified chondroid mesenchymal neoplasm mimicking epidural abscess: a case report

Joshua Estin, Dev Patel, Lawrence Kenyon, Islam Fayed, Karthik Madhavan

Abstract Calcified chondroid mesenchymal neoplasm (CCMN) is a rare chondroid matrix-producing tumour characterized by distinctive histopathology and recurrent FN1-receptor tyrosine kinase gene fusions. Reported cases have predominantly involved the distal extremities and temporomandibular joint, with no previously reported spinal cases. We present the first reported spinal epidural lesion morphologically consistent with CCMN. A 40-year-old male presented with progressive mid-thoracic back pain after a self-reported …

31.08.2026journal-article

International Journal of Innovative Technologies in Social Science

BIOLOGICAL TREATMENT OF SEVERE ASTHMA: A COMPARATIVE ANALYSIS OF TEZEPELUMAB, MEPOLIZUMAB, BENRALIZUMAB, AND DUPILUMAB

Agnieszka Filarecka, Piotr Przybyszewski, Emilia Przybyszewska, Julia Gatniejewska, Martyna Sienicka, Paulina Prudzic, Weronika Winiarska, Wiktoria Bełcikowska-Skowron, Aleksandra Siegmund, Marzena Chrapczyńska

Introduction: Bronchial asthma remains a significant clinical problem despite advances in pharmacological treatment. Approximately 5–10% of asthma patients suffer from a severe, uncontrolled form of the disease associated with frequent exacerbations, impaired lung function, reduced quality of life, and increased hospitalization rates. The introduction of biologic therapies targeting Th2-dependent inflammatory pathways has significantly improved treatment outcomes in this group of patients. Aim of the Study: The aim …

31.08.2026journal-article

The Korean Association For Persons With Autism

Comparing Gaze and Bodily Behaviors of Children with Autism Spectrum Disorder in Robot-Enhanced Therapy and Standard Human Treatment: A Secondary Analysis of the DREAM Dataset

Korean Association For Persons With Autism, Joungmin Kim

This study examined the differences in gaze and body behaviors of children with autism spectrum disorder (ASD) during robot-enhanced therapy (RET) and standard human treatment (SHT). Using the DREAM dataset, 2,234 intervention sessions conducted with 54 children (RET=28, SHT=26) were analyzed with linear mixed-effects models, controlling for task type, age, and autism severity. Compared with SHT, RET produced significantly greater horizontal gaze (β=.057, p

31.08.2026journal-article

Revista Brasileira Multidisciplinar

As marcas da desigualdade em mulheres negras com câncer de mama no Brasil:

Filipe Monteiro de Oliveira, Helder Matheus Alves Fernandes, Eric Wenda Ribeiro Lourenço, Marina Ferreira de Sousa, Jueme Nascimento dos Santos

Abstract: Black women's access to breast cancer treatment highlights significant inequalities in the health system, related to racial discrimination, socioeconomic barriers, and lack of information. In this context, health education strategies are essential to promote more inclusive care and reduce these disparities. Thus, this study seeks to understand the importance of discussions on ethnic-racial relations in Brazil, focusing on black women and the conditions that involve their access to treatment and prevention …

31.08.2026journal-article

Medicine Insights

A Discussion on Chronomedicine in the Treatment of Constipation Based on the Najia Method of Midnight-Noon Ebb-Flow Theory

Xiaoru Zhou, Jing Liu, Yaming Xu, Ruihui Wang

This paper systematically discusses the diagnostic and therapeutic principles of applying chronomedicine to the management of constipation from the perspective of the Najia method of midnight-noon ebb-flow theory. Also known as biological clock therapy, chronomedicine employs midnight-noon ebb-flow acupuncture to select acupoints according to the diurnal waxing and waning of qi and blood as well as the opening-closing rhythm of meridians, serving as an important component of traditional Chinese medicine chronoacupu …

31.08.2026journal-article

Journal of Gynecology and Reproductive Health

Bridging the Gap in Cancer Prevention: Impact of a Structured Cancer Awareness and Counselling on Cancer Knowledge, Risk Perception, and Screening Awareness Among Adult Women an Observational Pre-Post-Test Study

Sunita Ghike, Anand Pathak, Kamlesh Madankar, Jueely Pathak, Sharayu Chaoji, Pradnya Pathak, Narendra Ghike, Malini Joshi

Background: Cancer is a major global public health challenge, accounting for nearly 20 million new cases and 9.7 million deaths worldwide in 2022. In India, breast, cervical, and oral cancers constitute a substantial proportion of cancers among women. Despite the availability of effective preventive measures and screening programmes, awareness regarding cancer risk factors, early warning signs, hereditary cancer, genetic counselling, and screening remains inadequate, resulting in delayed diagnosis and poorer outcom …

31.08.2026journal-article

Journal of Mechanics in Medicine and Biology

MULTIPHOTON MICROSCOPY COMBINED WITH POLARIZATION IMAGING FOR EARLY DIAGNOSIS OF TUMOR TISSUE ABNORMALITIES

ZONGRU JIA, YUNFENG MA, WANG CHENG, YONG BAI, ZHE WANG, FANG BAI, ZHIXI ZHANG

Early-stage tumor tissues exhibit microstructural and optical property abnormalities, face challenges in achieving label-free, high-resolution, and accurate identification. Multiphoton microscopy (MPM) and polarization imaging can reflect tissue morphology, metabolism, and microscopic polarization characteristics, offering new approaches for early diagnosis of tumor abnormalities. This study aimed to investigate the application value of multiphoton microscopy combined with polarization imaging in the diagnosis of e …

31.08.2026journal-article

Current Opinion in Allergy & Clinical Immunology

Mechanisms and prospects of fecal microbiota transplantation in urticaria treatment via the gut skin axis

Xueli Yao, Keyang Wang, Ping Wang

Purpose of review This review focuses on fecal microbiota transplantation (FMT) for urticaria via the gut skin axis, highlighting its timeliness and clinical relevance as an emerging strategy for refractory urticaria. Recent findings Recent studies confirm that gut microbiota dysbiosis drives urticaria pathogenesis via immune regulation and mast cell activation, with preliminary clinical data showing FMT can alleviate symptoms and restore gut barrier function. Summary FMT holds promise as a novel therapeutic option …

31.08.2026journal-article

Cancer Immunology Research

A High Density of Impaired Tertiary Lymphoid Structures Is Associated with Higher Tumor Stage and Recurrence in Non–Muscle-Invasive Bladder Cancer

Sarah Péricart, Marie Tosolini, Mathieu Roumiguie, Axelle Saint, Laetitia Largeaud, Pauline Gravelle, Nathalie Van Acker, Pierre Brousset, Bernard Malavaud, Camille Laurent

Abstract Tertiary lymphoid structures (TLS) have emerged as critical immune niches within the tumor microenvironment across various cancers. However, their structural organization and functional roles in non–muscle-invasive bladder cancer (NMIBC) remain poorly characterized. In this study, we comprehensively characterized TLS in NMIBC using en bloc resected primary diagnostic specimens, which enabled high-resolution spatial mapping and quantitative histological assessment across a large cohort of primary tumors (97 …

31.08.2026journal-article

Thoracic Cancer

Delayed Occurrence of Lung Cancer Leptomeningeal Metastasis and Era‐Associated Post‐ LM Survival: A 14‐Year Single‐Center Cohort Study

Xiaoxing Gao, Jie Gao, Qiuyue Ye, Chen Wei, Qing Zhou, Xiaoyan Liu, Minjiang Chen, Jing Zhao, Hanping Wang, Xiaoyan Si, Wei Zhong, Yan Xu, Mengzhao Wang

ABSTRACT Introduction Leptomeningeal metastasis (LM) is a devastating complication of lung cancer. We investigated the clinical and molecular evolution of LM in the modern targeted‐therapy era and factors associated with post‐LM survival. Methods We retrospectively analyzed 201 patients with cytologically confirmed lung cancer LM diagnosed between November 2012 and May 2026. Patients were classified by LM diagnosis date (2012–2016 vs. 2017–2026). Intervals from lung cancer and Stage IV diagnosis to LM were compared …