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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
19.08.2026journal-article

Frontiers in Artificial Intelligence

AI-mediated intergenerational skill transfer: enhancing ESG literacy and sustainable consumption among aging populations

Anuja Paul, Astle, Sujata Roy

As nations face two significant megatrends—demographic aging and digital transformation—there is a need to align technological innovation with overarching sustainability goals. This study examines the application of Artificial Intelligence (AI) to improve intergenerational skill transfer, thereby enabling aging populations to substantially contribute to the enhancement of Environmental, Social, and Governance (ESG) literacy and Sustainable Development Goal 12 (Responsible Consumption and Production). This examines …

19.08.2026journal-article

Frontiers in Aging

A minimal three-arm oral regimen for healthspan: mechanistic alignment with transcriptomic signals from a large parental-lifespan GWAS

Ngo Cheung

A large genome-wide association study of parental lifespan was reported in 2019. A later transcriptome-wide association study (TWAS) based on those summary statistics identified a set of transcriptional programs associated with longer genetically predicted survival, including increased brain NAD + salvage, especially NMNAT2, reduced glucose-stimulated insulin secretion, a shift toward synaptic pruning with less broad plasticity, and a glial pattern characterized by relatively greater microglial and lower astrocytic …

19.08.2026journal-article

Asia-Pacific Psychiatry

Prevalence and Incidence of Dementia for Schizophrenia and Other Primary Psychotic Disorders: A Systematic Review and Meta‐Analysis

Mengyi Gao, Minxiu Ji, Caidi Zhang, Shuying Wang, Chun Wang, Yikang Zhu, Xiaochun Qiu, Raymond C. K. Chan, Stefan Leucht, Xinyi Cao, Chunbo Li

ABSTRACT People with psychotic disorders have higher dementia risk. This study aimed to investigate the prevalence and incidence of dementia in this population. Data were synthesized through meta‐analysis (including subgroup and sensitivity analyses) and narrative synthesis. The pooled dementia prevalence was 24.3% (95% CI: 20.5%–28.5%, I 2 = 84.7%, p

19.08.2026journal-article

Journal of Financial Economic Policy

Empowering MENA’s future: how financial inclusion bridges the aging population and economic growth from public good theory

Ismail Khan, Haseeb Ur Rahman, Naveed R. Rehman, Mustafa Rehman Khan

Purpose Despite the growing body of literature on population age structure (PAS) and economic growth, empirical evidence on the role of financial inclusion (FI) in moderating the effect is quite scarce, particularly for the Middle East/North Africa (MENA) region. This study aims to investigate the moderating impact of FI on the relationship between PAS and economic growth from the perspective of public good (PG) theory in MENA countries. Design/methodology/approach Using a sample of 10 MENA countries (i.e. Algeria, …

19.08.2026journal-article

International Migration

Rethinking Mobile Ethnography: Spatial and Social Experiences of Older Migrants

Tuğçe Tezel, Basak Bilecen, Nardi Steverink

ABSTRACT Europe's ageing population includes a growing number of older migrants whose experiences of ageing in place require methods that capture mobility, place, and social participation. Mobile ethnography, particularly walking/go‐along interviews, offers valuable opportunities to examine how older migrants engage with everyday environments. Yet existing mobile research with older migrants has often focused on participants able to take part in walking interviews, leaving less attention to how mobile ethnography c …

19.08.2026journal-article

BMC Public Health

Impact of specialized mobility services on independent travel, economic outcomes, and well-being for people with low vision and blindness: an international survey

Maxime Bleau, Kopila Kafle, Min Wang, Soutongnoma Safiata Kaboré, Jorge Luis Cueva-Vargas, Yingzi Xiong, Joseph Paul Nemargut

Abstract Background Though independent mobility has a considerable impact on an individual’s quality of life, employability, and social participation, few studies have examined the impact of specialized mobility services for people with visual impairments (PVI) globally. This study examines the impact of these services on independent travel and how it relates to social determinants of health for adults with low vision and blindness. Methods PVI 18 years of age or older were recruited via social media platforms or a …

19.08.2026journal-article

BMC Geriatrics

Hearing loss, social isolation, and frailty-state transitions in older adults: a longitudinal multistate analysis of CHARLS and HRS

Hongbing Yu, Tong Wu, Shufen Li, Hongqun Jiang, Yuanping Xiong

Abstract Background Frailty is dynamic, but the relationships of hearing loss, social isolation, and their coexistence with transitions between frailty states remain unclear. We examined their associations with frailty progression, recovery, and death in two longitudinal ageing cohorts. Methods We included 4,068 China Health and Retirement Longitudinal Study (CHARLS) participants (mean baseline age, 72.0 years; baseline, 2011; median follow-up, 7.0 years) and 9,769 Health and Retirement Study (HRS) participants (me …

19.08.2026journal-article

OBM Geriatrics

Home Dental Care to Homebound Older Adults in Primary Healthcare: A Mixed-Method Study

Bubacar Embaló, Jhenyfer Amanda Ciriaco Canhete, Gabriel Schmitt da Cruz, Daniela de Rossi Figueiredo, Heloisa Godoi, Ana Lúcia Schaefer Ferreira de Mello

The study aimed to understand the provision of home dental care for homebound older adults within the context of primary healthcare. A mixed-methods, concurrent, parallel, and cross-sectional study was conducted. Quantitative data were collected from 123 homebound older adults through structured questionnaires and oral examinations and analyzed using descriptive and bivariate statistics. Qualitative data were collected through interviews with 37 homebound older adults and/or caregivers and eight primary healthcare …

19.08.2026journal-article

Journal of Applied Gerontology

Experiences of Family Caregivers Supporting Older Adults With Limited English Proficiency in Accessing Preventive Healthcare: A Qualitative Interpretive Study

Sara Imanpour, Victoria Williams, Elvis Junior Dun-Dery, Amamah Noor

This study explored how immigrant family caregivers support older immigrant adults with limited English proficiency (LEP) in using primary and preventive care and how these roles shape caregivers’ lives. A qualitative phenomenological study was conducted with 32 immigrant family caregivers of older adults with LEP in the United States, purposively recruited from prior LEP-focused studies. Participants completed one interview, and data were analyzed using an interpretative phenomenological, descriptive thematic appr …

19.08.2026journal-article

Advanced Healthcare Materials

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel

ABSTRACT Aging is a significant risk factor of neurodegenerative disorders (NDs) such as Huntington's, Alzheimer's, Parkinson's, amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS). Although several clinical, neuroimaging, and biomarker‐based diagnostic approaches are available for NDs, their limited sensitivity for early‐stage detection, disease specificity, and prediction of disease progression continue to present significant clinical challenges, often resulting in delayed diagnosis and therapeutic i …

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19.08.2026journal-article

Ulumuna

Tazkiyah al-Nafs and Digital Piety: Redefining Spiritual Practices among Older Muslim Women

Titin Nurhidayati, Rofiatul Hosna, M. Nafiur Rofiq

This study explores the redefinition of spiritual practices through the lens of tazkiyah al-nafs and digital piety among urban Muslim women in the domestic sphere. Amid spiritual marginalization and urban isolation, the research examines how technology serves as a spiritual mediator and a “virtual ṭariqah” that facilitates religious independence. Using an interpretive phenomenological design, data were collected from ten elderly Muslim women in Jember who integrate artificial intelligence (AI) and digital devices i …

19.08.2026journal-article

Cardiovascular Diabetology

Fatty liver index-defined hepatic steatosis and impaired fasting glucose differentially associate with incident diabetes and cardiovascular events in older adults: a nationwide cohort study

Young Sang Lyu, Minae Park, Hee Kyung Kim, Sojeong Park, Kyoung Hwa Ha, Youngmin Yoon, Jin Hwa Kim, Sang Yong Kim, Dae Jung Kim, Ho-Cheol Kang, Wonsuk Choi

Abstract Background Hepatic steatosis and prediabetes are increasingly prevalent among older adults; however, their respective impacts on cardiometabolic outcomes remain unclear. We aimed to evaluate the associations of hepatic steatosis and prediabetes with incident diabetes and cardiovascular outcomes in this population. Methods This nationwide cohort study included 142,518 adults aged ≥ 65 years without diabetes. Hepatic steatosis was defined using the fatty liver index (FLI ≥ 60), and impaired fasting glucose ( …

19.08.2026journal-article

Gazi Üniversitesi Fen Bilimleri Dergisi Part C: Tasarım ve Teknoloji

Effect of Saltwater Aging on the Mechanical Performance of Polyethylene Matrix Glass, Basalt, and Hybrid Fiber Reinforced Composites

Muhammed Hüseyin Güzel, Tuncay Ateş, Gürol Önal

In this study, the long-term mechanical performance of low-density polyethylene (LDPE) matrix composites reinforced with glass, basalt, and glass/basalt hybrid fibers in a marine environment was investigated. Composite specimens produced by the hot-press method were aged in a 3% NaCl saltwater solution for five months. Within the scope of the study, water absorption measurements were performed, and axial tensile and three-point bending tests were conducted. Experimental results showed that mechanical properties dec …

19.08.2026journal-article

SLEEP Advances

Novel sleep metrics derived from chest-worn accelerometers are associated with dementia risk: The ARIC Neurocognitive Study

Keran W Chamberlin, Lacey H Etzkorn, Adam P Spira, Kening Jiang, Lin Yee Chen, Ciprian Crainiceanu, Vadim Zipunnikov, Jennifer A Schrack

Abstract Study Objectives 1) To develop an open-source method to identify time in bed (TIB) and related sleep parameters from chest-worn accelerometers; 2) To quantify the associations between derived sleep parameters and dementia risk. Methods Sleep parameters were estimated using new methods applied to movement and posture information extracted from the Zio® XT onboard accelerometer worn on the chest by participants in the Atherosclerosis Risk in Communities (ARIC) Study (2016-2017). Methods were (1) calibrated b …

19.08.2026journal-article

The Kaohsiung Journal of Medical Sciences

Metabolic Syndrome and Dementia Risk in Older Adults: A Narrative Review

Hyojin Park, Mallika Chuansangeam, Yuan‐Han Yang

ABSTRACT Dementia is a major global health issue in aging societies. Metabolic syndrome (MetS), a cluster of metabolic abnormalities, has been proposed as a modifiable risk factor for dementia, although existing evidence remains inconsistent. This review examined recent studies on the association between MetS and dementia risk in older adults. We searched PubMed for original studies published between January 1, 2014, and July 15, 2024, using the keywords “metabolic syndrome” and “dementia.” Fourteen studies met the …

19.08.2026journal-article

Acta Psychiatrica Scandinavica

The Association Between Lithium Use and Physical Comorbidities Across Age Groups: A Cross‐Sectional Study From the Global Aging and Geriatric Experiments in Bipolar Disorder ( GAGE ‐ BD ) Project

Ni Xu, Orestes V. Forlenza, Peijun Chen, Soham Rej, Ariel G. Gildengers, Osvaldo P. Almeida, Hilary P. Blumberg, Annemiek Dols, James E. Emanuel, Lisa T. Eyler, Esther Jiménez, Federica Klaus, Jennifer B. Levin, Laura Montejo, Benoit Mulsant, Regan E. Patrick, Tarek K. Rajji, Shangying Tsai, Eduard Vieta, Sara Weisenbach, Sigfried Schouws, Joaquim Radua, Bartholomeus C. M. Haarman, Martin Alda, Tomas Hajek, Andrew Toyin Olagunju, Stephen Olamide Oluwaniyi, Beny Lafer, Kürşat Altınbaş, Antonio L. Teixeira, Izabela G. Barbosa, Jair C. Soares, Giovana B. Zunta‐Soares, Vicent Balanzá‐Martínez, Sonia Ll. Vidal‐Rubio, Christian Simhandl, Nicole Korten, Martha Sajatovic, Xin Yu, the GAGE‐BD initiative

ABSTRACT Introductions Lithium remains the first‐line maintenance treatment for bipolar disorder (BD), yet its safety in older‐age BD (OABD) is uncertain due to limited large‐scale data. OABD patients often experience more severe physical comorbidities compared to younger BD patients, but systematic evidence regarding lithium's association with these conditions is lacking. This study examined the association between lithium use and physical comorbidities across age groups using the international Global Aging and Ge …

19.08.2026journal-article

Frontiers in Bird Science

Raptors’ contributions to people and human–raptor conflicts worldwide: an expert assessment

Santiago Zuluaga, F. Hernán Vargas, Juan M. Grande

Wildlife provides a wide range of nature’s contributions to people (NCP). At the same time, while they provide beneficial contributions, several detrimental contributions and/or human–wildlife conflicts (HWC) may also arise, particularly for wild predators and scavengers. Thus, interdisciplinary approaches that explicitly address both beneficial and detrimental contributions can make wildlife conservation efforts more effective. Despite this, historically, there has been an overall lack of interdisciplinary researc …

19.08.2026journal-article

Frontiers in Microbiology

Molecular transmission network analysis of HIV-1 among older adults in Central China: a cross-sectional study in Shaodong City

Xiaobai Zou, Wei Liu, Jieyu Zhou, Jinghang Zhang, Jie Chen, Jingxin Li, Wenxiu Deng, Huan Chen

Objective The ageing population poses emerging challenges to HIV prevention, particularly in regions with high proportions of older adults. We conducted a cross-sectional study of 513 newly diagnosed HIV-infected individuals in Shaodong City, Hunan Province, China, between 2021 and 2025, with a focus on individuals aged ≥60 years. Methods HIV-1 pol sequences were amplified, sequenced, and analyzed for subtype distribution and transmitted drug resistance (TDR). Molecular transmission networks were constructed using …

19.08.2026journal-article

Geriatrics

Experience of Respite Care with Alternating Housing Among People with Dementia: A Mixed-Methods Study

Mirkka Söderman, Annelie K. Gusdal, Lena-Karin Gustafsson

Background: In line with international aging policies, most people with dementia receive care at home. Community-based respite services aim to relieve, support, or share caregiving responsibilities. More person-centered knowledge based on experiences from this group is needed to increase informed decisions about planning of qualitative respite care. The aim of this study is to describe how people with dementia experience respite care with alternating housing, i.e., living partly at home, partly in residential care, …

19.08.2026journal-article

International Journal Semiarid

O PAPEL CULTURAL DA DANÇA NYANGA: ÚNICA E AUTENTICA DOS POVOS NYUNGUE

Lucas Armindo Curalinho

This article aims to analyze the cultural role of Nyanga dance, an artistic expression practiced in the southern part of Tete Province, particularly in the districts of Changara and Marara and in the city of Tete. The study is part of the Government’s Five-Year Program (2020–2024), which promotes sociocultural research to value, preserve, and promote Mozambican cultural heritage. The relevance of this work lies in the unique cultural characteristics of Nyanga dance in the Southern African region and the risk of its …

19.08.2026journal-article

JMIR Rehabilitation and Assistive Technologies

Deep Learning–Based Automated Clinical Gait Assessment From Kinematic Data in People With Stroke: Development and Validation Study

Zhexuan Gu, Jiaqi Li, Wenbin Zhou, Kenneth N K Fong, Lin Wang, Eng Keong Lua, Patrick W H Kwong, Yancheng Yuan

Abstract Background Gait impairment is a prevalent sequela of stroke. Although observational gait analysis remains a standard clinical practice for assessing neuromotor impairments in people with stroke, it is prone to subjective bias. Consequently, objective assessment is required to inform effective rehabilitation protocols. Objective This study aimed to validate a deep learning framework for automating clinical gait assessment using kinematic data. Methods This study was conducted in a university-affiliated gait …

19.08.2026journal-article

Frontiers in Immunology

Integrated multi-omics profiling identifies aging-related molecular signatures and convergent interferon signaling in systemic lupus erythematosus

Hongwei Zeng, Donge Tang, Yong Dai, Qinxin Zhang, Wenhan Du, Jing Du, Haiyan Yu, Jiayu Gu, Wei Zhang

Background Systemic lupus erythematosus (SLE) is characterized by chronic immune activation and molecular alterations that overlap with aging-related biological processes. However, how these alterations are organized across molecular layers and whether they converge on shared regulatory networks remain incompletely understood. Methods We performed an integrative multi-omics analysis combining in-house proteomic and phosphoproteomic data from 130 patients with SLE and 90 healthy controls (HCs) and publicly available …

19.08.2026journal-article

European Journal of Nutrition

Synergistic effects of synbiotic, protein supplementation, and resistance training on inflammation, oxidative stress, and muscle strength in older adults with type 2 diabetes mellitus: a RCT triple-blinded study

Marta Ferreira Bastos, Priscila Larcher Longo, Guilherme Eustáquio Furtado, Joselma Rodrigues dos Santos, Ariana Tito Rodrigues, João Vitor Oliveira Carvalho, Adriana Machado Saldiba de Lima, Guilherme Carlos Brech, André Luis Lacerda Bachi, Marcelo Paes de Barros, Larissa Augusta de Sousa, Rodrigo Assunção de Oliveira, Carolina Rego Chaves Dias, Julia Maria D’Andrea Greve, Angelica Castilho Alonso

Abstract Background Population aging poses major challenges for the management of type 2 diabetes mellitus (T2DM), particularly because inadequate protein intake, physical inactivity, and gut microbial dysbiosis may contribute to systemic oxidative stress and chronic low-grade inflammation (inflammaging). The present study investigated the combined effects of protein supplementation (P), synbiotic plus protein supplementation (SP), and resistance training (RT) on physical performance, body composition, glycemic con …

19.08.2026journal-article

Manuscript

Orthodoxy as a factor in shaping the self-consciousness of the Russian people in the works of N. A. Berdyaev, I. A. Ilyin, and P. B. Struve: source-critical aspects

Iuliia Sergeevna Usacheva

The purpose of the study is to determine how deeply and comprehensively Orthodoxy is examined in the works of N. A. Berdyaev, I. A. Ilyin, and P. B. Struve as a key factor in shaping the self-consciousness of the Russian people, and to what extent these works can serve as a historical source not only on the mentality of the Russian people and the various factors of its formation, but also on the intellectual history of Russia in the first half of the 20th century. The article selects those works by N. A. Berdyaev, …