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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
02.09.2026journal-article

The American Journal of Tropical Medicine and Hygiene

A Sustainable Treatment Protocol for Organophosphate Poisoning in Rural Kenya for Facilities without Intensive Care Units and Where Transfer Is Not Possible

Jerome Koleski, Sommer Aldulaimi, Jonathan Nthusi

ABSTRACT. Organophosphate poisoning is a common method of attempting suicide in developing countries, particularly in rural areas. The current WHO protocols emphasize intubation and transfer to a facility with intensive care. Both recommendations are beyond the resources of many rural hospitals in developing countries and their poor patients. Because organophosphate poisoning is a commonly seen condition in Kenya and because intubation is beyond the equipment and training of many rural hospitals, a protocol involvi …

02.09.2026journal-article

The American Journal of Tropical Medicine and Hygiene

Arbovirus Circulation among Patients with Acute Encephalitis: West Nile Virus Infection among Humans in Bangladesh, 2022

Syeda Tasnuva Maria, Mallick Masum Billah, Quazi Ahmed Zaki, Sharmin Sultana, Francisco Averhoff, Gavin Cloherty, Nick Walsh, Tahmina Shirin

ABSTRACT. West Nile virus (WNV) is an emerging infectious disease causing neuroinvasive diseases, including meningitis and encephalitis. Although infection has been documented in birds in Bangladesh, WNV has not been detected in humans. Since 2007, the Institute of Epidemiology, Disease Control and Research in Bangladesh has conducted hospital-based acute encephalitis syndrome (AES) surveillance to monitor Japanese encephalitis (JE), which is typically detected in 2% to 3%. Our study aimed to determine the presence …

02.09.2026journal-article

Critical Pathways in Cardiology: A Journal of Evidence-Based Medicine

Contemporary Evaluation and Management Strategies for Tricuspid Regurgitation

Sajjad Ahmadi-Renani, Stephan von Haehling, Constanze Schmidt, Sepideh Taghavi, Marzieh Mirtajaddini, Razieh Omidvar, Nasim Naderi

Background: Tricuspid regurgitation (TR) is a common but historically under-recognized valvular heart disease. Although mild to moderate TR was long considered benign, accumulating evidence indicates that clinically significant TR is associated with right ventricular failure, hepatic congestion, recurrent hospitalization, and increased mortality. Aims: This review aims to provide a comprehensive overview of contemporary evaluation and management strategies for TR across its clinically relevant spectrum, with partic …

02.09.2026journal-article

Chronic Illness

How organizational conditions shape development and assessment of patient-Centered lifestyle interventions targeting hard-to-reach patients with cardiac disease or type 2 diabetes

Sanne Lykke Lundstrøm, Karin Burns, Nana Folmann Hempler, Nina Ingemann Christensen, Ulla Toft, Ole Snorgaard, Louise Meinertz Jakobsen

Objectives This study explores how organizational conditions affect the development and implementation of dialogue-based methods for patients with cardiac disease or type 2 diabetes, focusing on hard-to-reach groups. Methods Utilizing audio recordings, transcripts, and field notes from 2018-2019, we applied the Theoretical Domains Framework to analyze how individual and group processes influenced the development and implementation of initiatives. Results The study identified five key themes: environmental context a …

02.09.2026journal-article

Pharaonic Journal of Science

Comparative Evaluation of 2D Digital Intraoral Radiography and Cone Beam Computed Tomography (CBCT) in Assessing Peri-Implant Marginal Bone Loss: A Clinical and Diagnostic Accuracy Study

Sarmad Hamozi

Periodic measurement of MBL allows for the timely recognition and treatment of peri-implantitis. Despite the wide availability of two-dimensional digital intraoral radiography, which also provides a low radiation dose, the impossibility of assessing the buccal and lingual cortical plates is a serious limitation in diagnosing the condition. Cone-beam computed tomography provides a three-dimensional image and gives an opportunity to assess the bone defects in multiple planes. This work evaluates the diagnostic effect …

02.09.2026journal-article

Journal of Public Health and Preventive Medicine

Remote and Hybrid Work and Sedentary Behaviour Among Working Adults: A Scoping Review of Behavioural Evidence and Cardiometabolic Research Gaps

siying qiu, hanyu du, Yuexian Tao

Background: Remote and hybrid work arrangements may improve autonomy and reduce commuting, but may also reduce routine movement and promote prolonged sitting. Evidence on sedentary behavior in these settings has expanded, whereas direct evidence on cardiometabolic outcomes remains limited. Objective: To map behavioral evidence on sedentary exposure in remote and hybrid work, describe its measurement and distribution across work arrangements, and characterize cardiometabolic outcomes as an evidence gap. Methods: We …

02.09.2026journal-article

Clinical Journal of Sport Medicine

The Lifetime and One-Year Prevalence of Concussion in Male and Female High School Students in Alberta

Amanda M. Black, Jocelyn H. McCallum, Paul H. Eliason, Brent E. Hagel, Carolyn A. Emery

Objective: To examine the lifetime and one-year prevalence of concussion, including suspected and medically diagnosed, among high school students (ages 14-19 years) in Alberta, Canada. Design: Cross-sectional survey. Setting: High schools across Alberta, Canada. Participants: Grade 10 to 12 students from 24 schools. Independent Variables: Students completed an anonymous and validated online survey during class (October 2018-March 2019), including their sex and participation in sport and recreational activity. Main …

02.09.2026journal-article

Frontiers in Digital Health

Multimodal medical diagnosis: a mini review of LLM–vision fusion models in low-resource healthcare settings

Kahakashan Ashraf, Md. Hamid Hosen, Nuzhat Tabassum Farah, Md Kishor Morol, Tze Hui Liew, Dip Nandi, Mashiour Rahman, Abdullah Al Jubair

Recent advances in large language models (LLMs) and vision transformers have enabled multimodal systems that integrate clinical text with medical imaging for diagnostic decision-making. While these systems show promising results on benchmark datasets in well-resourced research settings, their applicability in low-resource healthcare environments where diagnostic disparities are most severe remains limited and poorly understood. This mini review synthesizes key developments in LLM–vision fusion architectures from 20 …

02.09.2026journal-article

Frontiers in Pharmacology

Clinical application of sugammadex in renal impairment: pharmacokinetics and pharmacodynamics

Hao-Wei Lee, Pao-Shan Chen, Min-Jia Li, Chih-Shung Wong

Sugammadex, a modified γ-cyclodextrin, rapidly and predictably reverses aminosteroid neuromuscular blockade by directly encapsulating rocuronium and vecuronium, thereby avoiding the cholinergic adverse effects associated with acetylcholinesterase inhibitors. Because both free sugammadex and the sugammadex–rocuronium complex are eliminated predominantly through renal excretion, the use of sugammadex in patients with severe renal impairment remains a topic of debate. This review summarized current evidence on sugamma …

02.09.2026journal-article

JAMA Network Open

Care Navigation for Methamphetamine Use Disorder

Alia Al-Tayyib, Deborah J. Rinehart, Karina G. Duarte, Aiden Gilbert, Chris Newton, Ryan Loh, Emily Bacon, Scott A. Simpson

Importance Stimulant-involved deaths continue to increase in the US, and methamphetamine use remains a weighty public health concern. Treating methamphetamine use disorders is complicated. Contingency management has demonstrated the best effectiveness but is not widely implemented. Objective To examine the effectiveness of dedicated care navigation in linking patients to treatment. Design, Setting, and Participants This prospective randomized clinical trial was conducted at an integrated safety-net health system in …

02.09.2026journal-article

Clinical Journal of the American Society of Nephrology

Associations of Plant- and Animal-Sourced Ultra-Processed Foods and Incident CKD in the Cardiovascular Health Study

Courtney M. Hill, Alyssa Feinberg, Casey M. Rebholz, Rozenn Lemaitre, Amanda M. Fretts, Kerri L. Wiggins, Nona Sotoodehnia, James S. Floyd, Benjamin Lidgard, Nisha Bansal, Bruce M. Psaty, Hyunju Kim

Background: Ultra-processed foods (UPFs) are associated with adverse health. Plant foods can be highly processed. It is not clear whether plant- and animal-sourced UPFs are associated chronic kidney disease (CKD) risk. Methods: Data came from the Cardiovascular Health Study, a prospective cohort of 2,661 older adults (≥65 years). The exposure was UPF intake, classified as plant- or animal-sourced in servings/day using the Nova framework from food frequency questionnaires (1989-1990, 1995-1996). The outcome was inci …

02.09.2026journal-article

Medicina

Absorbable Synthetic Meshes in Implant-Based Breast Reconstruction After Subcutaneous Mastectomy: A Systematic Review with Clinical and Economic Considerations

Aurimas Dobilinskas, Loreta Pilipaitytė

Background and Objectives: Implant-based breast reconstruction following subcutaneous mastectomy is widely performed; however, the optimal strategy for implant support remains controversial. Absorbable synthetic meshes have emerged as lower-cost alternatives to acellular dermal matrix (ADM), yet their clinical and economic value remains incompletely defined. Materials and Methods: A systematic review was conducted in accordance with PRISMA guidelines using PubMed, Scopus, and Web of Science databases. Studies evalu …

02.09.2026journal-article

Chinese Medicine

Ivangustin, a sesquiterpene lactone from Inula japonica Thunb., attenuates neuroinflammation through covalent inhibition of ubiquitin-conjugating enzyme UBE2L3

Mengyuan Qiao, Hanyue Gan, Yuying Shi, Shan Yang, Ting Liu, Xiaofei Shen, Wenbin Wu

Abstract Background Neuroinflammation is a key driver and an important therapeutic target of neurodegeneration. Dysregulated nuclear factor-κB (NF-κB) signaling plays a central role in neuroinflammation and depends on M1 and K63 ubiquitination of NF-κB essential modulator (NEMO). Ivangustin (IVA) is a sesquiterpene lactone isolated from Inula japonica Thunb., a traditional Chinese medicine has been used to treat inflammatory diseases. But its anti-neuroinflammatory effects and molecular targets remain unclear. Purp …

02.09.2026journal-article

Africa Journal of Nursing and Midwifery

Exploring Psychological Support Systems in Mental Health Units: An Interpretive Phenomenological Study of Nurses’ Post-traumatic Clinical Incident Lived Experiences

Magdalena Karomo, Dr Daniel Opotamutale Ashipala

Background: Nurses often face traumatic events in clinical settings, leading to significant psychological, physical and professional consequences. Understanding their lived experiences, coping strategies, and institutional support is essential for designing effective, culturally sensitive interventions that protect their well-being and promote safe patient care. Objective: The objective of this study was to explore the lived experiences of nurses exposed to a traumatic clinical incident, focusing on its psychologic …

02.09.2026journal-article

International Journal of Computer Information Systems and Industrial Management Applications

ADAPTIVE CONTEXT-AWARE MULTIMODAL TRANSFORMER FRAMEWORK FOR ROBUST RESPIRATORY DISEASE DIAGNOSIS

R. SARADHA, M. SUNDARA RAJAN

Early detection and accurate diagnosis of respiratory diseases are remaining critical for the timely clinical interference and treatment. Many of the conventional diagnostic systems are relying on the unimodal datasets or static multimodal fusion strategies that tends in limiting the ability in capturing the respiratory diseases. Despite the success of recent multimodal learning approaches, where the practical limitations are remaining unresolved. This study proposes an Adaptive Context-Aware Multimodal Transformer …

02.09.2026journal-article

Clinical and Experimental Neuroimmunology

Bidirectional Neuro‐Immune Interactions of the Orexin/Hypocretin System: A Systematic Review With Conceptual Synthesis

Jean Claude Hakizimana, Zephyrin Izukwizabigenza, Marie Gorette Kampire, Joseph Mucumbitsi, Abdullateef Isiaka Alagbonsi

ABSTRACT Background Beyond regulating sleep, the orexin/hypocretin system participates in bidirectional neuro‐immune interactions that may influence neurodegenerative diseases (NDs) and chronic inflammatory conditions. This systematic review aimed to conceptually synthesize evidence on these interactions and their clinical implications. Methods Following PRISMA 2020 guidelines, a comprehensive search was performed in PubMed, Embase, Web of Science, Scopus, and PsycINFO. Studies were included if they reported origin …

02.09.2026journal-article

Problems of Gathering Treatment and Transportation of Oil and Oil Products

INNOVATIVE TECHNOLOGY FOR MAIN PIPELINE OVERHAUL BY INSULATION COATING REPLACEMENT

V.A. Ivanov, A.V. Aksenov, V.A. Rybin, Ya.M. Kurbanov, E.L. Chizhevskaya, N.A. Borisov, T.G. Ponomareva

Main pipelines are one of the principal methods for hydrocarbon raw materials transportation over long distances. The majority of these pipelines are laid underground. This, in turn, has a number of advantages and disadvantages. For example, when performing certain technological operations aimed at maintaining the operability of an underground pipeline, additional time is required for excavation work, specifically, uncovering the pipeline from the backfill soil that is trapping it. Maintaining the required reliabil …

02.09.2026journal-article

Journal of Clinical Medicine

Days Alive and out of Hospital at 30 Days After Curative Gastrectomy for Gastric Adenocarcinoma: Complication-Severity Gradient and Readmission Burden

Adem Ozcan, Gizem Gunes, Ali Bal, Abdulkadir Unsal

Background/Objectives: Days alive and out of the hospital at 30 days (DAOH30) integrates survival, index hospitalization, and readmission. We characterized DAOH30 after gastrectomy, assessed its complication-severity gradient and readmission burden, and explored its association with an index-cancer-excluded Charlson Comorbidity Index (CCI). Methods: This single-center retrospective analysis included adults undergoing R0 total gastrectomy or subtotal distal gastrectomy for non-metastatic gastric adenocarcinoma betwe …

02.09.2026journal-article

Scientific Reports

Latent profile analysis of benefit finding in maintenance hemodialysis patients and its association with treatment adherence

Xianghao Chen, Wenli Cai, Xiaodan Lin, Haidan Xie, Jialian Huang, Huifeng Song, Xiaozhou Zhou

Abstract Maintenance hemodialysis (MHD) patients experience prominent negative emotions, and dialysis outcomes/prognosis rely heavily on treatment adherence. Few studies have explored the relationship between latent Benefit Finding (BF) categories and adherence. This study aims to identify BF’s latent characteristics in MHD patients and analyze their link to adherence for targeted interventions. From Oct. 2024 to Mar. 2025, 250 MHD patients were convenience-sampled from 2 tertiary hospitals in Guangzhou. Measuremen …

02.09.2026journal-article

International Journal of Medicine and Health

Association Between Ultra-Processed Food Consumption and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Adults

Lila Amila, Kurnia Agustina Sitompul, Maretha Primariayu, Dalilah Salsabila Salma, Siti Aria Rahmani Novianto, Marsha Zahrani, Nadia Mardiana Hudan

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease globally, but its association with ultra-processed food (UPF) consumption under the new diagnostic framework has not been systematically synthesized. We systematically searched PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science for observational studies examining habitual UPF intake (NOVA classification) and MASLD/NAFLD in general adult populations using validated outcome ascertainment. Qualit …

02.09.2026journal-article

Journal of Clinical Medicine

Excessively High Maternal Total Cell-Free DNA Concentration and Fetal Growth Restriction in Singleton Pregnancies: A Retrospective Cohort Study

Lingling Xing, Xiaosha Jing, Ting Bai, Sha Liu, Jianlong Liu, Cechuan Deng, Tianyu Xia, Yunyun Liu, Xiang Wei, Yuan Luo, Quanfang Zhou, Qian Zhu, Hongqian Liu

Background/Objectives: Noninvasive prenatal screening (NIPS) fails in approximately 0.2% of cases due to high maternal plasma total cell-free DNA (t-cfDNA) concentration (≥0.6 ng/µL) confirmed after two DNA extraction attempts. The clinical implications of this quality control metric for fetal growth restriction (FGR) remain unknown. Methods: This retrospective cohort study, conducted in a major prenatal diagnosis center in China, involved pregnant women who underwent noninvasive prenatal screening (NIPS) between 2 …

02.09.2026journal-article

Journal of the Heart Valve Society

Impact of Preoperative COVID-19 Infection on Myocardial Injury and Outcomes After Aortic Valve Surgery in the Pre-Vaccination Era

Mohammed Hashem, Payam Haftbaradaran Esfahan, Daniel Daher, Anders Franco-Cereceda, Magnus Bäck

Objectives To determine whether preoperative COVID-19 infection before vaccine introduction was associated with postoperative myocardial injury and long-term adverse outcomes after surgical aortic valve replacement. Methods This prospective cohort study included patients undergoing surgical aortic valve replacement between July 2020 and May 2021. Preoperative COVID-19 infection status was determined by antibody testing. Baseline data were collected, and outcomes were identified through structured medical-record rev …

02.09.2026journal-article

Journal of Medical Humanities

Virtues and Narratives in Medicine: An Analysis and Collection of Virtue-Illustrating Stories in Medical Journals

Lauris C. Kaldjian, Brittany A. Bettendorf, Fabrice Jotterand

Abstract This paper draws from a framework of virtue ethics and narrative medicine to present a content analysis and teaching resource of virtue-illustrating stories found in medical journals. As acquired dispositions, virtues are cultivated not merely by listening to lectures but through reflection, experience, role-modeling, practice, and internalization. One way to encourage such cultivation is to use narratives to illustrate moral virtues in action. With this in mind, we identified a literature-based taxonomy o …

02.09.2026journal-article

Journal of Clinical Medicine

A Comparison of Medial and Lateral Ligament Balance in Functional Versus Simulated Mechanical Alignment in Total Knee Arthroplasty Across CPAK Phenotypes: A Single-Center Study

Anne Ruth van Meijeren, Daniëlle Langeloo, Hans-Peter van Jonbergen, Martin Stevens, Marrigje Floor Meijer

Background/Objectives: Despite the excellent long-term outcomes of total knee arthroplasty (TKA), up to 10% of patients remain dissatisfied. Robotic-assisted TKA enables individualized alignment strategies, such as functional alignment (FA). Proper alignment and soft tissue balance are considered key factors for positive clinical outcomes. This study compared medial and lateral ligament balance between simulated mechanical alignment (MA) and FA across different Coronal Plane Alignment of the Knee (CPAK) types using …