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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
20.08.2026journal-article

JDR Clinical & Translational Research

Nonlinear Association between Density of Dental Clinics and Dental Visits among Older Japanese

K. Honda, S. Kiuchi, K. Takeuchi, T. Kusama, K. Osaka, J. Aida

Objectives: Correcting clinic maldistribution is key to universal health care. The imbalance in dental clinic supply, characterized by both oversupply and undersupply, remains underexplored, and few studies link geographic distribution with patient utilization patterns. This study examined the association between the density of dental clinics and dental visits among the older Japanese population. Method: This repeated cross-sectional study used data from 3 waves (2016, 2019, and 2022) of the Japan Gerontological Ev …

20.08.2026journal-article

Biological Research For Nursing

Association Between Serum BDNF and S100 B Levels in Community-Dwelling Older Adults

Ryuzo Orihashi, Takumi Shiraishi, Toru Murakawa-Hirachi, Hiroshi Tateishi, Yutaka Kunitake, Hiroko Kunitake, Yoshito Mizoguchi

Population aging has made the maintenance of cognitive function and mental health in older adults a major public health priority. Brain-derived neurotrophic factor (BDNF) and S100 calcium-binding protein B (S100 B) are biomarkers of brain health, reflecting neurotrophic support and neuroinflammatory activity, respectively. The objectives of this study were to examine the association (a) between serum BDNF and S100 B levels and (b) between these biomarkers and cognitive function and depression in community-dwelling …

20.08.2026journal-article

International Journal of Environmental Research and Public Health

Facing Dementia in Primary Care: A Process Evaluation of a Multicomponent Practice Change Intervention to Improve Dementia Diagnosis in General Practice

Mark Yates, Caroline Gibson, Constance Dimity Pond, Stephanie Daly, Jessica Jebramek, Sharon Daniel, Lyn Phillipson, Kate Laver, Meredith Gresham, Edwin Tan, Henry Brodaty, Jamie Swann, Shahana Ferdousi, Annica Barcenilla-Wong, Nora Wong, Lee-Fay Low

Dementia is a leading cause of disability and death worldwide, yet diagnosis in primary care remains substantially lower than expected, delaying access to treatment, support and future care planning. The Facing Dementia Together Practice Change Program was developed as a co-designed, multicomponent intervention to improve dementia diagnosis in Australian general practice. A mixed-methods process evaluation used the RE-AIM framework with the addition of Appropriateness. The intervention included Primary Health Netwo …

20.08.2026journal-article

ACS Applied Energy Materials

Mechanism of Capacity Loss of Zinc Anodes during Calendar Aging

Ze Chen, Qiang Fu, Congxin Xie, Xianfeng Li

Abstract Zinc-based flow batteries (ZBFBs) hold significant promise for low-cost and safe large-scale energy storage; however, there has been a lack of focus on calendar aging and the corresponding strategies to mitigate capacity decay. Herein, we systematically examined the factors affecting the calendar aging of zinc anodes, identifying current density and dissolved oxygen (DO) as key contributors to capacity loss. Low interfacial impedance and deposition overpotential in oxygen-free electrolytes, especially at l …

20.08.2026journal-article

Frontiers in Medicine

Sarcopenia in older adults admitted to acute medical unit: a prospective observational study of feasibility and clinical outcomes

Vicky Kamwa, Zaki Hassan-Smith, Thomas Jackson, Elizabeth Sapey

Background Sarcopenia, the loss of skeletal muscle mass and function, has recently emerged as a significant health concern. It is common in older adults and linked to poor outcomes. It is dynamic and can improve or deteriorate over short periods of time. We aimed to determine its prevalence and changes during hospital admission and explore associations with clinical outcomes. Methods This was a Prospective, Observational Cohort, Feasibility Study. Older Adults (>65 years old) with an unplanned admission to an AMU i …

20.08.2026journal-article

Frontiers in Public Health

Cancer prevention and screening for people with intellectual disabilities in Europe: a systematic review and recommendations for policy and practice

Vladimir Vukovic, Peter Knapp, Kate Sykes, Margaret Denny, Oliwia Kowalczyk, Suzanne Denieffe, John Wells, Maarten Cuypers, Barrie Tyner, Kálya Yasmine Lima, Adela Elena Popa, Dalia Ismail Ibrahim, Rebecca Hansford, Trine Allerslev Horsbøl, Dragana Milutinović, Bilge Güvenç Tuna, Eda Başustaoğlu Şahin, Ayşegül Ilgaz, Amina Banda, Elif Sarac, Soner Doğan, Seda Cansu Yeniğün Akbulut, Bahar Aksoy, Dušanka Tadić, Mohammed A. Merzah, Pınar Soylar, Aysenur Doğan, Dragana Simin, Jasmin Mušanović, Damla Altin, Merve Sena Topkaya, Fatima Kassymbekova, Vladimir Trajkovski, Edanur Tar Bolacali, Louise Lynch, Eilish Burke, Martin McMahon

Introduction People with intellectual disability experience inequalities across the cancer care continuum, including lower screening participation, later-stage diagnosis, and higher cancer related mortality. Whether European cancer prevention and screening policies explicitly address this population has not been systematically mapped. Methods This review aimed to identify and synthesise European national and international policy frameworks, guidelines, and recommendations for cancer prevention and screening that ad …

20.08.2026journal-article

Working with Older People

Managing complex needs amidst limited formal care: informal support, reciprocity and loneliness among older adults in Vietnam

Anh Nu Nguyet Nguyen, Binh Huu Nguyen, Anh Xuan Nguyen

Purpose This study aims to examine how older adults in Vietnam manage complex care needs where formal care is limited and how informal support, reciprocity and loneliness intersect within these arrangements. Design/methodology/approach This paper draws on 90 semi-structured interviews with older adults, family carers and local stakeholders at urban and rural sites in southern Vietnam, conducted in 2024. Older-adult interviews formed the primary analytic data set, while carer and local-stakeholder accounts were used …

20.08.2026journal-article

Frontiers in Health Services

Supporting continuous glucose monitoring for people with serious mental illness and type 2 diabetes: a co-design study for a structured intervention

Jennifer V. E. Brown, Olivia Matthias, Jessica Hendon, Ramzi A. Ajjan, Najma Siddiqi, Ian Kellar, Peter A. Coventry

Introduction Individuals with serious mental illness (SMI), such as schizophrenia or bipolar disorder, are at a two- to threefold increased risk of developing type 2 diabetes and face significant health inequalities, including reduced life expectancy. Diabetes self-management in this population is challenging, and existing interventions are poorly suited to their needs. Continuous glucose monitoring (CGM) offers potential benefits but remains underused. This study aimed to co-design a logic model and programme theo …

20.08.2026journal-article

Frontiers in Aging Neuroscience

Acceptability and feasibility of an adapted Portuguese folk dance–based therapy in older adults with moderate-to-severe dementia and balance impairment

Ana Almeida, Vasco Caveirinha, Joana Felício, Rui Fontes, Patrícia João, Tânia Libório, Ana Piedade, Carlos Família, Catarina Godinho, Júlio Belo Fernandes

Introduction Population ageing has increased the prevalence of dementia, often accompanied by mobility impairments. It is essential to develop effective interventions and promote adherence among people with dementia. Culturally meaningful activities may enhance motivation, engagement, and rehabilitation outcomes. Methods A mixed-methods pilot study was developed to evaluate the acceptability and feasibility of an adapted Portuguese folk dance–based intervention among older adults with moderate to severe dementia an …

20.08.2026journal-article

Drug and Alcohol Review

High Awareness, Low Clarity: Knowledge of the Australian Capital Territory's Multi‐Drug Decriminalisation Reform Among People Who Use Illicit Drugs

Rachel Sutherland, Connor Graham, Caitlin Elizabeth Hughes, Anna Olsen, Chris Gough, Cate King, Amy Peacock

ABSTRACT Introduction In October 2023, the Australian Capital Territory became the first Australian jurisdiction to decriminalise possession of small quantities of multiple illicit drugs by law, introducing an alternative, legislated pathway enabling police to divert individuals to a health education and information session or issue a $100 expiation fine. This study examined awareness and understanding of this reform among two populations of people who regularly use illicit drugs in Canberra. Methods Cross‐sectiona …

20.08.2026journal-article

Healthcare

Effects of a Fully Immersive Virtual Reality Exercise Game on Fear of Movement, Pain, and Disability in People with Chronic Non-Specific Low Back Pain: A Pilot Randomized Controlled Trial

Hana Alsobayel, Kholoud Almufaireej, Dalia Alimam, Hamad Alduaij, Afaf Shaheen, Hend Al-Khalifa

Background/Objectives: Low back pain (LBP) is a leading cause of disability worldwide, and exercise-based rehabilitation is recognized as an effective management strategy. However, adherence to exercise remains challenging. Fully immersive virtual reality (VR) exercise interventions may enhance engagement and clinical outcomes. This study aimed to examine the effect of a fully immersive VR exercise game on pain, fear-avoidance beliefs, and disability in individuals with chronic non-specific LBP. Methods: A single-b …

20.08.2026journal-article

American Journal of Speech-Language Pathology

A Qualitative Evidence Synthesis of Communication Partner Training: Exploring the Experiences of Communication Partners and People With Acquired Brain Injury

Nicholas Behn, Iben Christensen, Ian Kellar, Leanne Togher, Katerina Hilari, Madeline Cruice

Purpose: This study aimed to explore the experiences of adult communication partners (CPs) of individuals with acquired brain injury (ABI) who received communication training and, where reported, the experiences of individuals with ABI who attended or participated in the training. Method: A qualitative evidence synthesis was conducted. Electronic searches were completed in CINAHL Ultimate, APA PsycInfo, APA PsycArticles, Medline, Embase, AMED, Scopus, NeuroBITE, and PubMed for studies published until August 2025. I …

20.08.2026journal-article

PLOS Biology

Social interactions between people of same and different generations shape longitudinal changes in interpersonal neural synchrony, loneliness, and social connection

Ryssa Moffat, Guillaume Dumas, Emily S. Cross

Loneliness is globally acknowledged as a severe and burgeoning health risk, fueling interest in helping people of all ages form meaningful social connections. One promising approach consists of intergenerational social programs. While behavioral and qualitative evidence derived from such programs promise health and wellbeing benefits, the physiological consequences of repeated intergenerational encounters remain unknown. Insight into physiological changes will shed light on the mechanisms of social connection. We c …

20.08.2026journal-article

Surface Review and Letters

Effect of combined PM and aging treatment on the microstructural evolution and corrosion resistance of NiTi alloys

Qusay Abdulsattar Mohammed, Sokhiba Israilova, Akanksha Mishra, Ripendeep Singh, F. Nie

Nickel–titanium alloys produced through powder metallurgy were subjected to controlled aging treatments to examine how thermal exposure influences microstructural evolution, oxide formation, and corrosion performance. Aging at 600 °C for 1–3 h progressively reduced porosity and promoted the development of intermetallic phases such as Ni 3 Ti, Ni 4 Ti3, and Ti 2 Ni, along with increasingly uniform TiO 2 surface layers. SEM, EDS, and XRD analyses confirmed enhanced oxide coverage and phase redistribution with longer …

20.08.2026journal-article

Widyariset

KOLOIMBA MITH AND THE INCHES RELATIONSHIP IN TOLAKINESS PEOPLE

Jamaluddin Muchtar

Indonesian society is rich in myths. However, there are contradictory views among the people who believe and do not believe it. The uncertain truth of a myth followed by human fear of the truth of the myth itself. Myth is not just a mere story, but also cultural phenomenons, a product of human imagination, contain some meanings and social fact believed by the supporters. By taking a case study of Koloimba myth in Tolaki community, Southeast Sulawesi, the study aims to analyze (1) the structure of the myth miteme as …

20.08.2026journal-article

Current Alzheimer Research

Structural and Ultrastructural Neuropathological Changes in Alzheimer's Disease: Biomarkers, Current Insights and Emerging Perspectives

Sreenivasulu Sura, Emmanuel Oshiogwe Okwuofu, Sowmya Ramakrishnappa, Saravanan Jagadeesan, Siti Saleha Binti Masrudin, Mohamad Aris Mohd Moklas, Krishna Chaitanya Reddy Dandala, John Paul Judson, Nurul Huda Mohd Nor

Abstract: Alzheimer's Disease (AD) involves progressive brain changes at both the structural and ultrastructural levels, which begin long before patients present with clinical symptoms. These changes relate to the complex processes of amyloid-β deposition, tau accumulation, synaptic damage, glial activation, impaired vascular function, and disruption of large-scale brain networks. Understanding these neurobiological changes is essential for improving diagnosis, biomarker development, and targeted therapy. We conduc …

20.08.2026journal-article

Pathogens

Patient-Level Discordance Between SCORE2 Cardiovascular Risk and PD-1/PD-L1 Checkpoint-Expression Profiles in People Living with HIV: A Secondary Cohort Analysis

Bogusz Aksak-Wąs, Karolina Skonieczna-Żydecka, Danuta Cembrowska-Lech, Miłosz Parczewski, Filip Lewandowski, Karol Serwin, Kaja Mielczak, Mateusz Bruss, Franciszek Lenkiewicz, Milena Rafalska-Kosior, Laura Lesiewska, Paulina Niedźwiedzka-Rystwej

Background: Conventional cardiovascular risk scores do not directly characterize immune checkpoint-expression phenotypes in people with HIV. We examined patient-level alignment between SCORE2 and PD-1/PD-L1 checkpoint expression in a secondary analysis of a previously characterized parent cohort. Methods: Data from 100 PWH followed at a single HIV center were analyzed. SCORE2, lipid parameters, systolic blood pressure, CD4+/CD8+ ratio, and flow-cytometric PD-1/PD-L1 expression on T-cell, B-cell, and NK-cell subsets …

20.08.2026journal-article

JAMA Otolaryngology–Head & Neck Surgery

TERT Promoter Variants, Older Age, and Prognosis in Papillary Thyroid Carcinoma

Vicente R. Marczyk, Sophie Li, Chia Chin Wu, Matthew A. Loberg, Ying Henderson, Meghan Martin, Sarah Hamidi, Steven Waguespack, Naifa Busaidy, Ramona Dadu, Priyanka Iyer, Mimi Hu, Victoria Banuchi, Anastasios Maniakas, Stephen Lai, Mark Zafereo, Michelle D. Williams, Sayed Mohsen Hosseini, Quanhu Sheng, George J. Xu, Eric C. Huang, Vivian L. Weiss, Maria Cabanillas, Jennifer R. Wang

Importance Older age at diagnosis is associated with worse outcomes in papillary thyroid carcinoma (PTC). The current American Joint Committee on Cancer tumor-node-metastasis staging system incorporates an age of 55 years or older as staging criteria. TERT promoter variants are also associated with aggressive disease. Objective To evaluate the interplay between age, TERT promoter variants, and survival outcomes in PTC. Design, Setting, and Participants This multi-institutional retrospective cohort study was conduct …

20.08.2026journal-article

Frontiers in Aging

Collagen-induced restructuring of astrocytes and vessels in organotypic mouse brain slices

Eva Steiner, Valentin Wolfgang, Christian Humpel

Introduction The brain exhibits high plasticity and responds to many forms of external stimuli, such as trauma, seizures, drugs, and biomaterials. Collagen is a non-toxic biocompatible protein that participates in the plastic reformation of the brain. In this study, we explored whether collagen can reconstruct astrocytes and brain vessels by using microcontact printing on organotypic mouse brain slices. Methods Organotypic brain slices from postnatal days 8–10 were prepared and connected to collagen microcontact pr …

20.08.2026journal-article

Frontiers in Psychology

The impact of therapeutic landscapes on the mental health of older adults: a systematic review

Yan Han, Bin Li, Yuxin Hou, Juan Zhang

Therapeutic landscapes, as an important form of health-promoting environmental intervention, provide a feasible approach to improving the mental health of older adults. However, their modes of action and underlying mechanisms require further clarification. Following the PRISMA guidelines, this study systematically searched Web of Science, Scopus, JSTOR, ScienceDirect, PubMed, and PsycINFO. Studies were selected according to the PICOS framework and assessed using the Crowe Critical Appraisal Tool (CCAT) and the JBI …

20.08.2026journal-article

npj Science of Food

Krill oil attenuates skeletal muscle atrophy during D-galactose-induced accelerated aging via an AMPK-dependent mechanism

Zi-Jian Wu, Xin-Yue Zhao, Yu-Hong Yang, Cheng-Cheng Wang, Yan Zheng, Shi-Xiang Wu, Cheng-Yu Yang, Han-Ni Wei, Qing-Yan Zou, Yu-Ming Wang, Lei Du

Abstract The global aging trend highlights the critical challenge of sarcopenia, which severely compromises both quality of life and overall survival time. This study aimed to investigate the effects of Antarctic krill oil (KO) on accelerated aging-induced skeletal muscle atrophy and its underlying mechanisms. An accelerated aging mouse model was established via daily intraperitoneal injection of 400 mg/kg D-galactose (D-gal) for 12 consecutive weeks. Concurrently, mice received oral gavage of KO or fish oil (FO) a …

20.08.2026journal-article

JMIR Formative Research

Performance of Two AI Approaches in ASReview Compared With Manual Screening for Dementia Care Literature Screening: Comparative Analysis

Dirk Steijger, Stella Thissen, Sil Aarts, Hilde Verbeek, Marjolein E de Vugt, Hannah Christie

Abstract Background Literature reviews rely on rigorous title and abstract screening by researchers, which is time-consuming. AI-assisted literature screening tools have been proposed to improve efficiency by prioritizing titles and abstracts with the highest likelihood of meeting the inclusion criteria, thereby reducing the need to screen all records. Objective This study aims to evaluate the performance of two AI-assisted screening approaches in ASReview (version 1.3; Department of Methodology and Statistics, Utr …

20.08.2026journal-article

Philosophical Transactions of the Royal Society B: Biological Sciences

How people use the peat swamp forests of the central Congo Basin

Cassandra Dummett, Ovide Emba Botuli, Shona J. Jenkins, Eustache Amboulou, Joe F. Langley, Jonas Ngouhouo-Poufoun, Corneille E. N. Ewango, Suspense Ifo, Simon Lewis

Abstract The central Congo Basin peatlands span 167 600 km2 and are the world's largest tropical peatlands. Hundreds of thousands of people live in the vicinity of the peatlands, but studies of how people use the peatlands do not, to our knowledge, exist. This article investigates people's use of peat swamp forests in three study sites in the Democratic Republic of Congo and the Republic of the Congo. Using participatory methods, we interviewed 407 people and learned that 100% of households use the peat swamp fores …

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20.08.2026journal-article

Journal of Materials Science: Materials in Engineering

Mechanical stability and degradation kinetics of a natural fiber biogeosynthetic composite from Typha domingensis and Boehmeria nivea under accelerated aging

Emersson Guedes da Silva, Luiz Diego Vidal Santos, Francisco Sandro Rodrigues Holanda, Alarico José da Silva Azerêdo, Renisson Neponuceno de Araújo Filho, José Joatan Rodrigues Júnior, Cicero Inácio da Silva Filho, Jémison Mattos dos Santos, Eliana Midori Sussuchi, Alceu Pedrotti

Abstract Lignocellulosic biocomposites offer a renewable alternative to petroleum-derived materials, yet their photodegradation behavior under accelerated weathering remains insufficiently characterized from a reliability standpoint. This study evaluated the mechanical performance and degradation patterns of a laminar biotextile–biogrid biocomposite intended as a biodegradable geosynthetic analogue for short- to medium-term erosion-control and soil-protection applications. The material was assembled from a Typha do …

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