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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Digital Bisnis: Jurnal Publikasi Ilmu Manajemen dan E-Commerce

Pengaruh Perceived Organizational Support terhadap Adaptive Performance

Ferdiansyah Maulana, Enjang Suherman, Flora Patricia Anggela

This study aims to examine the influence of Perceived Organizational Support on the Adaptive Performance of employees at PT. Glico Wings Karawang. Employees require adaptability to adjust to workplace changes, technological advancements, and organizational expectations. This quantitative study employed a survey-based approach, with a sample of 100 respondents selected via purposive sampling. IBM SPSS Statistics software was used to conduct validity and reliability tests, classical assumption tests (including normal …

03.09.2026journal-article

Frontiers in Public Health

Maternal per- and polyfluoroalkyl substances exposure and the co-occurrence of gestational diabetes mellitus and preeclampsia/eclampsia: a nested case–control study

Nana Li, Lu Li, Ying Deng, Meixian Wang, Yuting Li, Zhen Liu, Hong Kang, Jun Zhu, Ping Yu, Yanping Wang

Objective Few studies have investigated the relationship between maternal exposure to per- and polyfluoroalkyl substances (PFAS) and the co-occurrence of gestational diabetes mellitus (GDM) and hypertensive disorders of pregnancy, particularly preeclampsia/eclampsia (PE/E). The present study aimed to explore whether PFAS exposure is associated with the co-occurrence of GDM and PE/E. Methods This study enrolled 333 pregnant women diagnosed with both GDM and PE/E, and 360 healthy controls. First-trimester plasma conc …

03.09.2026journal-article

Frontiers in Surgery

Clinical outcomes of flap reconstruction following lower extremity soft tissue sarcoma resection: a single-center retrospective experience

Xinxin Guo, Jianpeng Li, Jingyu Zhang, Yongcheng Hu

Background Soft tissue sarcomas (STSs) represent a diverse category of tumors with a propensity for the lower limbs. Wide surgical resection is the primary therapeutic approach, often requiring immediate flap reconstruction with or without perioperative adjuvant therapy. This study aims to share our clinical experience and assess the efficacy of customized flap reconstruction designed according to the precise defect area after lower extremity STS resection. Methods This retrospective analysis reviewed 15 cases of l …

03.09.2026journal-article

Journal of Fish Health

Potential of Local Microalgae from Lembar Bay Waters for Climate Change Mitigation: Insights from Photosynthetic Assimilation Index

Damai Diniariwisan, Alis Mukhlis, Bagus Dwi Hari Setyono, Awan Dermawan, Rizky Regina Kawirian, Sri Hikmah Wulandari

Climate change mitigation requires innovative approaches to reduce atmospheric carbon dioxide (CO₂) through efficient and sustainable carbon fixation. Microalgae are promising biological agents because of their photosynthetic capacity to assimilate inorganic carbon into biomass. This study aimed to assess the potential of local microalgae communities in Lembar Bay waters, West Lombok, as carbon assimilation agents based on the relationship between chlorophyll-a, net primary productivity (NPP), and assimilation inde …

03.09.2026journal-article

INTERNATIONAL JOURNAL OF EDUCATION AND EVALUATION

Impact of Artificial Intelligence–Assisted Learning Tools on Academic Performance and Study Habits Among Secondary School Students in Nigeria

Tsoho Abraham Aliyu

The integration of Artificial Intelligence (AI)–assisted learning tools into educational environments has transformed students’ learning experiences globally, yet empirical evidence on their impact within the Nigerian secondary school context remains limited. This study investigated the effect of AI-assisted learning tools, such as ChatGPT and similar digital platforms, on academic performance and study habits among secondary school students in Nigeria. The study adopted a descriptive survey research design. A samp …

03.09.2026journal-article

Journal of Comparative Effectiveness Research

US population-level model of clinical impact of lorlatinib treatment on ALK+ metastatic non-small cell lung cancer outcomes

Adam Kasle, Devin Abrahami, David Veenstra, Robert Morlock, Priya Ramachandran, Lindsay Stansfield, Raymond Mak

Aim: Lorlatinib and alectinib are next-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) approved for the treatment of ALK-positive (ALK+) advanced/metastatic non-small cell lung cancer (NSCLC) after demonstrating superior efficacy over crizotinib (first-generation ALK TKI) in the CROWN and ALEX trials, respectively. This analysis estimated the US population-level clinical impact of first-line (1L) lorlatinib versus alectinib treatment for ALK+ advanced/metastatic NSCLC. Materials & meth …

03.09.2026journal-article

Healthcare

A Multi-Indicator Concentration Index for Primary-Care Reimbursement Analytics: Evidence from the Albanian Health-Insurance System

Tomi Thomo, Gjergji Koja, Bujar Elezi

Background: Public payers must regularly decide which prescribers to look at more closely, with records covering thousands of doctors per quarter and review capacity for only a fraction. How that choice is made bears on equitable access to reimbursed medicines as well as on public funds. Methods: We propose a multi-indicator concentration index scoring each prescriber 0–100 as the sum of nine weighted sub-scores, each measuring the doctor’s deviation from their primary-care centre median on one indicator from the p …

03.09.2026journal-article

International Journal of Computer Science and Mathematical Theory

Emerging Trends in Artificial Intelligence: A Review of Transformative Technologies and Applications

Dahiru Haruna Usman

The current trends in Artificial Intelligence technologies continually transform multiple business sectors while changing how humans connect with machines. Contemporary technology views AI as its essential component instead of remaining as a separate specialized study field. A review of primary AI trends coupled with applications and obstacles in modern AI research served as the focus of this academic paper. Healthcare decision transparency integrates with financial needs to enable smart infrastructure deployment b …

03.09.2026journal-article

Egyptian Rheumatology and Rehabilitation

Hand grip strength: age- and gender-stratified normative data in Egyptian population-based study by the Egyptian Academy of Bone and Muscle Health

Yasser El Miedany, Maha Elgaafary, Walaa Elwakil, Rahma A. Elziaty, Reem Sadek, Reem H. Abd Alrahman, Sarah Hossam Abdelrahman, Mohamed Eldaramlly Omar, Abdelrahman Rashwan Radwan, Waleed Hassan, Marwa Yahia, Olfat Gamal Elsaeid, Asmaa Elbanhawy, Marwa Abdrabo, Mohamed El Koumy, Israa Qutob, Bassant Samir, Safaa Mahran

Abstract Objective This study aimed to establish age- and gender-stratified normative data for hand grip strength (HGS) in a population-based sample of healthy Egyptian adults and to analyze its relationship with various socio-demographic and anthropometric parameters. Methods This cross-sectional study evaluated 2,247 healthy Egyptian participants (900 men, 1,347 women). HGS was measured in kilograms (kg) using a digital hand dynamometer following a standardized bilateral protocol. Anthropometric data (including B …

03.09.2026journal-article

Nutrition Today

Gut Microbiome Testing: From Laboratory Methods to Clinical Meaning

Lauren Cornell

As direct-to-consumer (DTC) gut microbiome testing continues to move into mainstream nutrition and medical practice, clinicians are increasingly confronted with reports built on laboratory methods that sound sophisticated but vary widely in what they can realistically deliver. This second article in a 2-part series is designed to demystify the science behind these tests by clearly explaining the primary methodologies they rely on, including 16S rRNA sequencing, quantitative polymerase chain reaction (qPCR), shotgun …

03.09.2026journal-article

Journal of Patient-Reported Outcomes

Identifying risk of prescription analgesic misuse in chronic pain: screening utility and clinical cut-offs of the Japanese PROMIS Rx Misuse 7a in a low-opioid prescribing environment

Keiko Yamada, Tomohiko Nishigami, Takashi Kimura, Kenta Wakaizumi, Miho Nakanishi, Noriyo Takahashi, Takao Setsu, Takeru Shiroiwa, Kazuhiro Yoshiuchi

Abstract Background Most screening tools for prescription analgesic misuse were developed in high-opioid prescribing contexts. This study evaluated the measurement properties and screening utility of the Japanese version of the PROMIS Prescription Pain Medication Misuse–Short Form 7a (PROMIS Rx Misuse 7a) in a strictly regulated, low-opioid prescribing environment. Methodology A cross-sectional web-based survey was conducted among 500 Japanese adults with chronic pain who were currently prescribed analgesics. The s …

03.09.2026journal-article

Frontiers in Oncology

Clinical trial design for primary brain tumors: a problem-based framework for neuro-oncology practice

Diego Gómez-Puerto, Jesús Yaringaño, Antonio Di Muzio, Oriol Mirallas, María Vieito

Background Primary brain tumor trials may produce an uninterpretable or non-generalizable answer when biological mismatch, inadequate intratumoral exposure, restrictive eligibility, molecular rarity, unstable controls, and disease-specific endpoint ambiguity are addressed separately. The practical problem is not the absence of modern methods, but failure to select and combine them according to the dominant threat to the development decision. Methods We performed a practice-facing narrative synthesis of methodologic …

03.09.2026journal-article

Clinical Infectious Diseases

A Multistate Investigation of Serious Adverse Events, including Deaths, following Ceftriaxone Injections, September 2024–August 2025

Rebecca Pierce, Radhika Agarwal, Dumbani Kayira, Maribeth C Lovegrove, Nimalie D Stone, Kelly M Hatfield, Jennifer Lind Lyles, Melissa Morrison, Wes Stubblefield, Sherri L Davidson, Karen Landers, Scott Harris, Rachana Bhattarai, Theresa Dulski, Juliet Stoltey, Lauren Biehle, Josh Hoffner, Argentina Charles, JoAnna Wagner, Haley Beeman, Michael J Curran, Grace Lee, Riley Moore, Jacy Walters, Gargi Patel, Dat Tran, Jenna Sinkevitch, Marco Tori, Christopher Wilson, Simone Godwin, Shehzana Hussaini, Allison G Lafferty, Shaina Bernard, Shannon Ruelle, Catherine O Dasenbrock, Meredith Sheridan, Frank Wackes, Rachna Kapoor, Ramesh Gopalaswamy, Kiran M Perkins

Abstract Background Reports of ceftriaxone serious adverse events (SAEs), including deaths, from multiple jurisdictions during December 2024–January 2025 prompted a nationwide investigation to evaluate product safety, characterize SAEs, and assess for changes in baseline adverse event occurrence via national databases. Methods In February 2025, CDC issued a national call for cases, defined as SAEs involving death or CPR within six hours of ceftriaxone injection, not otherwise explained and occurring in non-ICU sett …

03.09.2026journal-article

Journal of Clinical Ultrasound

Ultrasonographic Evaluation of Cavum Septum Pellucidum Dimensions and Morphology in the Second Half of Pregnancy: A Prospective Cross‐Sectional Study

Somayeh Shirazinezhad, Somayeh Khanjani, Sonia Rostami Ghorbani, Mohammadreza Elhaie

ABSTRACT Objective To determine normative ultrasonographic dimensions, morphology, and visualization rate of the cavum septum pellucidum (CSP) in structurally normal singleton fetuses between 19 and 40 weeks of gestation and to assess correlations with gestational age and fetal biometric parameters. Methods This prospective cross‐sectional study enrolled 600 consecutive singleton pregnancies with normal fetal anatomy at Beheshti Hospital, Isfahan, Iran (2024–2025). Transabdominal ultrasound was performed in standar …

03.09.2026journal-article

Journal of Microscopy and Ultrastructure

Hyalinization in Dentistry: Pathogenesis, Mechanisms, and Clinical Implications

Roja Lakshmi Karri, Hasini Nelakurthi, Amrutha Rudraraju, NavaratnaSowmya Chinta

Abstract Hyalinization is a key histological feature that provides valuable insights into various dental and systemic conditions. It refers to the deposition of a glass-like, homogenous substance in tissues, often signaling tissue damage, necrosis, or abnormal collagen dynamics. In dentistry, hyalinization is observed in periodontal disease, orthodontic treatments, and dental pulp health, as well as in systemic conditions. During orthodontic treatment, excessive forces can induce ischemia in the periodontal ligamen …

03.09.2026journal-article

British Journal of Sports Medicine

Digital therapeutic combining exercise and cognitive–behavioural therapy reduces pain in patients with chronic patellofemoral pain: a multicentre randomised controlled trial

Jae-Young Park, Sanghee Lee, Jong-Min Kim, Sang Hak Lee, Moon Jong Chang, Kyu Sung Chung, Man Soo Kim, Seong Hwan Kim, Dong Jin Ryu, Tae Hyun Park, Chi-Hyun Choi, Chan Yoon, Chong Bum Chang, Jin Goo Kim

Objectives To evaluate whether an 8-week smartphone-based multidisciplinary digital therapeutic (DTx) combining exercise and cognitive–behavioural therapy reduced usual knee pain at 8 weeks compared with education and exercise instruction in chronic patellofemoral pain (PFP). Methods This multicentre, parallel-group randomised controlled trial included 216 participants with chronic PFP, defined as anterior or retropatellar pain lasting at least 3 months with activity-related provocation, recruited from orthopaedic …

03.09.2026journal-article

British Journal of Sports Medicine

Resistance training and depressive symptoms in subcortical vascular cognitive impairment: secondary results of a randomised clinical trial

Ryan S Falck, Cindy K Barha, Ryan G Stein, Sofia Grant, Alexis Bullock, Ken M Madden, Jennifer C Davis, Roger Tam, Teresa Liu-Ambrose

Objectives Cerebral small vessel disease (CSVD) is associated with depressive symptoms. Exercise may reduce depressive symptoms for people with CSVD. We examined the effects of progressive resistance training (PRT) on depressive symptoms among adults with CSVD and mild cognitive impairment (ie, subcortical vascular cognitive impairment (SVCI)). Methods A single-site, 12-month, parallel group, secondary analysis of a randomised controlled trial (ClinicalTrials.gov identifier: NCT02669394 ). Community-dwelling adults …

03.09.2026journal-article

JAMA Network Open

Regional Variation in Bladder Cancer Clinical Trial Availability in the US

Koral U. Shah, Salvador Jaime-Casas, Ruchi Agarwal, George Zhang, Xiaochen Li, Vitor Abreu de Goes, Daniela V. Castro, Benjamin Mercier, Ruth Simon, Samuel Dickter, Lily M. Lau, Jaya Goud, Akasha Dukkipati, Jadon Fann, Lauren Lau, Joshua Lee, Kyra Shah, Ethan Swarat, Miguel Zugman, Nazli Dizman, Ali Moradi, Regina Barragan-Carrillo, Abhishek Tripathi, Charles B. Nguyen, Alex Chehrazi-Raffle, Sumanta K. Pal

Importance Geographic disparities in cancer clinical trial access are well described in the US, but patterns in bladder cancer remain poorly defined. Objective To evaluate bladder cancer trial availability across US counties and its associations with epidemiologic and socioeconomic factors. Design, Setting, and Participants This cross-sectional study of completed, open, or active bladder cancer clinical trials from June 1, 2019, to June 1, 2025, on ClinicalTrials.gov used data on county-level incidence, mortality, …

03.09.2026journal-article

BMC Medical Informatics and Decision Making

Development and preliminary evaluation of a WeChat mini-program-based mobile pharmacy management assistance system in a Chinese women and Children’s hospital

Jianhui Yang, Zhida Hong, Tianquan Lin, Wubin Lin, Wei Zhuang, Xiuxian Lin, Wanlong Lin

Abstract Background Traditional pharmacy management, which relies on paper- and computer-based methods, is often inefficient and inflexible. There is an urgent need to develop support tools to address these challenges. The WeChat mini-program has been applied in multiple fields because it is readily accessible within the WeChat ecosystem. Its use in pharmacy management may support more accessible and flexible workflows. Objective To develop and evaluate a WeChat mini-program-based Mobile Pharmacy Management Assista …

03.09.2026journal-article

Journal on Innovation and Sustainability RISUS

Transformational leadership and knowledge infrastructure as enablers of digital readiness

Muhammad Saqib Iqbal, Muhammad Fawad Khan, Zulhasni Abdul Rahim, Hamza Iftikhar, Mommin Arshad Durrani, Qudrattullah Omerkhel

This study investigates how transformational leadership enhances digital readiness among Malaysian micro, small, and medium enterprises (MSMEs) by mediating knowledge infrastructure. It addresses the managerial question of how leaders’ decisions translate into technological preparedness in resource-constrained contexts. Drawing on Transformational Leadership Theory, Dynamic Capabilities Theory, and the Knowledge-Based View, this study proposes and tests the Leadership–Knowledge Infrastructure Readiness Model (LKIRM …

03.09.2026journal-article

JMIR Research Protocols

Patient-Centered Clinical Decision Support for Recommended Screenings in French Primary Care: Protocol for a Multicenter Mixed Methods Feasibility Study

Pierre-Yves Meunier, Laurent Magaud, Romain Varnier, Emmie Goetz, Melinda Bekaddour, Ludivine Albert, Inès Khati, Ilhem Bensekka, Julie Haesebaert, Denis Maillet, Julien Péron, Laurent Letrilliart

Background Primary care professionals (PCPs) are responsible for identifying eligibility and supporting patient decisions for a wide range of recommended screenings. However, the number of recommendations (42 for adults in France), complex eligibility criteria, limited consultation time, and competing priorities hinder their systematic delivery. Clinical decision support systems (CDSSs) with patient decision aids may help structure prevention-focused consultations and support shared decision-making, but their feasi …

03.09.2026journal-article

Medical Technology and Public Health Journal

An Analysis of Emergency Drills in Enhancing Self-Readiness and Emergency Preparedness Behavior Among Employees at Taman Dolan Tourist Site

Rachmy Rois, Anita Sulistyorini, Dian Puspitaningtyas Laksana

Natural tourism areas are highly vulnerable to disasters, making employees a crucial factor in ensuring visitor safety. One important mitigation strategy is the implementation of emergency drills, also known as emergency response exercises. However, the effectiveness of training in improving employee preparedness remains uncertain. This study aimed to analyzed the effect of emergency drills on self-readiness and emergency preparedness behavior among employees at Taman Dolan Nature Tourism, Batu City. A quantitative …

03.09.2026journal-article

Electronics

A Hybrid VMD–GWO–BiLSTM–Attention Framework for Accurate State-of-Health Prediction of Lithium-Ion Batteries Under Complex Degradation Dynamics

Chenglin Ding, Hui Liu, Enze Hu, Xuesheng Wang

Accurate State-of-Health (SOH) prediction for lithium-ion batteries is essential for the safe and stable operation of Battery Management Systems (BMSs). However, achieving high-precision estimation remains challenging due to the complex interplay of non-stationary degradation characteristics, observation noise, and bidirectional temporal dependencies. This study proposes a robust hybrid temporal prediction framework integrating Variational Mode Decomposition (VMD), Bidirectional Long Short-Term Memory (BiLSTM) netw …

03.09.2026journal-article

Review of Clinical Pharmacology and Pharmacokinetics

Therapeutic landscape for diabetic macular edema: durable strategies with a focus on aflibercept 8 mg

Martín Roberto Basile-Alvarez, Erick André Escalante-Buendía, Karen A. Palacios-Aguirre, Alejandro Ortega Desio, Omar Yaxmehen Bello-Chavolla

To evaluate current therapies for diabetic macular edema (DME), with emphasis on durability, safety, access, and the evidence supporting aflibercept 8 mg. An expert-selected narrative synthesis of primary clinical trials, pharmacologic studies, regulatory documents, and selected real-world evidence published from January 1, 2000, through August 8, 2026, was performed. Anti-vascular endothelial growth factor therapy remains first-line treatment for most center-involved DME with visual impairment, but observation or …