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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Публічне управління і право: історія, теорія, практика

ПУБЛІЧНЕ УПРАВЛІННЯ У СФЕРІ СОЦІАЛЬНО-ПСИХОЛОГІЧНОЇ РЕАБІЛІТАЦІЇ ВІЙСЬКОВОСЛУЖБОВЦІВ І ВЕТЕРАНІВ ВІЙНИ: НОРМАТИВНО-ПРАВОВЕ ЗАБЕЗПЕЧЕННЯ

Оксана Лазор, Олег Лазор, Ірина Юник

Досліджено нормативно-правове забезпечення публічного управління у сфері соціально-психологічної реабілітації військовослужбовців і ветеранів війни в умовах повномасштабної збройної агресії проти України. Обґрунтовано актуальність удосконалення системи публічного управління, зумовлену стрімким зростанням кількості військовослужбовців і ветеранів війни, які потребують комплексної соціальної, психологічної, медичної та професійної підтримки. Проаналізовано конституційні засади публічного управління у сфері соціально- …

28.08.2026journal-article

Odovtos - International Journal of Dental Sciences

Effects of Surgical and Non-surgical Periodontal Therapy on Renal Function and Inflammatory Biomarkers and Mortality in Patients with Chronic Kidney Disease: An Umbrella Review

Anny Marcela Vivares-Builes, María Teresa Pertúz-Rondón, German Márquez-Toro, Carlos Pizarro-Herrera, Andrés Alonso Agudelo-Suarez, Carlos M. Ardila

Periodontitis and chronic kidney disease (CKD) share common pathophysiological mechanisms, with periodontitis acting as a chronic inflammatory comorbidity that exacerbates systemic inflammation in CKD patients. This study aimed to analyze the effect of surgical and non-surgical periodontal therapy on renal function, inflammatory biomarkers, and mortality in patients with CKD according to the available evidence. An umbrella review was conducted, including systematic reviews and meta-analyses from databases such as P …

28.08.2026journal-article

Applied Sciences

Comparative Development and Engineering Evaluation of Low-Cost Individualized Hand Rehabilitation Orthoses with Alternative Finger Actuation Mechanisms

Branko Štefanovič, Norbert Ferenčík, Jozef Živčák

Hand rehabilitation orthoses play an important role in restoring upper-limb function in individuals with impaired grasp ability; however, selecting an actuation mechanism that balances functional performance, manufacturing complexity, and production cost remains a significant engineering challenge. This study aimed to develop and compare three low-cost hand and forearm rehabilitation orthosis prototypes within a common subject-specific digital workflow based on three-dimensional (3D) scanning, computer-aided design …

28.08.2026journal-article

Glosains: Jurnal Sains Global Indonesia

Comparison of Low-Level and High-Intensity Laser Therapy Effects on Functional Outcomes in Knee Osteoarthritis

Fauzan Ahmad, Mohammad Barlian Nugroho, Djoko Witjaksono, Viera Wardhani

Background: Low-Level Laser Therapy (LLLT) and High-Intensity Laser Therapy (HILT) are widely used nonpharmacological interventions for patients with knee osteoarthritis (KOA). However, scientific evidence comparing the effectiveness of these two therapies on functional outcomes remains limited. Objective: To compare the effects of LLLT and HILT combined with quadriceps bench exercises on knee function, walking speed, and knee proprioception in patients with KOA. Methods: This randomized controlled trial used a pre …

28.08.2026journal-article

Journal of Mechanics in Medicine and Biology

ADAPTIVE IMPEDANCE CONTROL OF LOWER LIMB REHABILITATION ROBOT OPTIMIZED BY THE SPARROW SEARCH ALGORITHM FOR SPORTS FRACTURE REHABILITATION

HANG YIN, XI LING

Traditional lower limb rehabilitation robots suffer from low motion intention recognition accuracy and poor human-robot compliance, which may cause secondary injury to athletes with lower limb fractures. To solve this problem, this study proposes a hybrid control system combining the sparrow search algorithm optimized back propagation neural network (SSA-BP) and adaptive impedance control (AIC). The SSA-BP model is adopted to extract features from surface electromyography (sEMG) signals and recognize human motion i …

28.08.2026journal-article

Frontiers in Medicine

Early diagnosis and therapy of Chlamydia psittaci pneumonia: insights from chest CT, tNGS, and omadacycline in 34 cases

Qiuting Jiang, Xiaoli Zhao, Yuan Zhu, Xinmin Zhu, Shaohua Hu, Huajuan Zhou

Objective This study retrospectively analyzed the clinical characteristics and management strategies of 34 patients with Chlamydia psittaci pneumonia. We aimed to evaluate the diagnostic value of subpleural-predominant pulmonary CT manifestations combined with bronchoalveolar lavage fluid targeted next-generation sequencing (tNGS), and to assess the clinical efficacy and therapeutic advantages of omadacycline in this patient cohort. Methods Clinical data were retrospectively collected from patients diagnosed with C …

28.08.2026journal-article

Lombok Medical Journal

Virtual Reality Therapy as an Innovative Intervention in Mental Health: A Literature Review

Afra Ruchudinia Mufida, Aisyah Adinda Kurniawan, Diska Aprisa Lestari, Eprel Pranacinsa Tanagan, Azizatul Adni

The advancement of digital technology has driven innovation in mental health interventions, including Virtual Reality Therapy (VRT), a technology-based approach that enables patients to experience immersive and controlled three-dimensional environments. This literature review aims to examine the concepts and effectiveness of VRT in managing mental health disorders. The findings indicate that VRT is effective in reducing symptoms of anxiety, depression, post-traumatic stress disorder (PTSD), and substance use disord …

28.08.2026journal-article

Annals of Surgical Oncology

Prospective Clinical Trial on Expanding the Eligibility Criteria for Targeted Axillary Dissection after Neoadjuvant Systemic Therapy in Breast Cancers with Advanced Nodal Disease

A. J. T. Lee, B. H. H. Cheung, D. T. K. Suen, A. Kwong

Abstract Background Targeted axillary dissection (TAD) is an established axillary restaging approach in breast cancer after neoadjuvant chemotherapy (NAC), but evidence to date has focused largely on clinical N1 disease with limited nodal involvement. For higher nodal burden patients, axillary dissection (AD) is still frequently performed despite high axillary pathologic complete response (pCR) rates. We hypothesized that TAD is noninferior to AD for nodal staging in patients with advanced nodal disease. Patients a …

28.08.2026journal-article

Frontiers in Medicine

Clinical benefit without sweat chloride response after ETI therapy in an adult with cystic fibrosis bearing the L467F;F508del complex CFTR allele: a case report and the role of AI-assisted chest CT in longitudinal monitoring

Marcela Kreslova, Daan Caudri, Isabelle Sermet-Gaudelus, Aurelie Hatton, Punitkumar Makani, Vaclav Koucky, Malgorzata Libik, Hana Hrdinova, Libor Fila, Nela Stastna, Eva Furstova, Radka Bittenglova, Jan Baxa, Josef Sykora, Milan Macek

Background Elexacaftor/tezacaftor/ivacaftor (ETI) is the standard of care for most people with cystic fibrosis (CF) who carry at least one F508del allele. However, predicting responses to CFTR modulators in rare or complex CFTR genotypes is challenging. Sweat chloride concentration (SCC) and patient-derived functional assays assessing CFTR-mediated chloride transport are commonly used to classify modulator responsiveness. Carriers of the p.Leu467Phe;p.Phe508del (henceforward legacy nomenclature: L467F;F508del) comp …

28.08.2026journal-article

European Journal of Clinical Microbiology & Infectious Diseases

Selective statin therapy and nasal staphylococcal colonisation: a retrospective case-control study

Zahraa Abbas, Jeffery Hughes, Bruce Sunderland, Richard Parsons, Matthew Rawlins, Owen Robinson, Petra Czarniak

Abstract Background Nasal Staphylococcus aureus ( S. aureus ) colonisation is a key risk factor for serious infections. Statins, used for hypercholesterolaemia and cardiovascular disease prevention, have been linked to gut microbiome dysbiosis, but their impact on nasal bacterial colonisation remains unclear. Purpose To examine whether statin use, individual statins, and statin dose intensity are associated with nasal S. aureus colonisation, and whether associations differ between methicillin-sensitive S. aureus (M …

28.08.2026journal-article

Majalah Obstetri & Ginekologi

Difference between Javanese traditional music therapy and hypnopregnancy audio on improving sleep quality in third-trimester pregnant women

Efrila Antika Puji Lestari, Noviyati Rahardjo Putri, Luluk Fajria Maulida, Ratih Puspita Febrinasari, Atriany Nilam Sari

HIGHLIGHTS Both Javanese traditional music therapy and hypnopregnancy audio produce clinically meaningful improvements in sleep quality among third-trimester pregnant women, reinforcing the value of culturally adapted and non-pharmacological interventions in antenatal care. Multiple auditory-based relaxation approaches may offer comparable benefits, providing flexible options for integration into maternal health programs and supporting SDG 3 on maternal well-being. ABSTRACT Objective: This study aimed to compare th …

28.08.2026journal-article

Frontiers in Psychology

Relationship between sleep–wake patterns, occupational stress and sickness absence among nurses

Katarzyna Lisowicz, Katarzyna Tomaszewska, Dawid Makowicz, Marek Sobolewski, Krystyna Kowalczuk

Individual sleep–wake characteristics play an important role in daily functioning and adaptation to shift work. They are associated with alertness, sleep quality, cognitive performance, concentration, and the ability to cope with occupational demands. High levels of occupational stress and chronic fatigue have also been identified as factors associated with sickness absence among nursing staff. Objective The aim of the study was to assess the relationship between sleep–wake characteristics, occupational stress, and …

28.08.2026journal-article

Journal of Primary Care Dentistry and Oral Health

Chairside Direct Fabrication of Cheek Plumpers on an Existing Complete Denture for Facial Esthetic Rehabilitation: A Clinical Case Report

Guddolla Venkata Prasanna, Karukayil Amrutha Mohanbabu, Vinnakota Dileep Nag

Abstract Esthetic rehabilitation in completely edentulous patients involves restoration of function and facial appearance. Loss of buccal fat, muscular tone, and alveolar bone support may result in sunken cheeks and compromised facial esthetics. Cheek plumpers support the facial musculature but are commonly incorporated during fabrication of new dentures; however, some patients may be unwilling to replace well-fitting existing prostheses. This clinical case report describes the conservative management of a patient …

28.08.2026journal-article

Europe’s Journal of Psychology

Effectiveness of cognitive behavioural therapy on sleep outcome for patients with chronic fatigue syndrome in a routine clinical service

Chotiman Chinvararak, Olivia Sterry, Trudie Chalder

Objective We aimed to study the effectiveness of CBT for sleep difficulties in patients with chronic fatigue syndrome/myalgic encephalitis (CFS/ME). Method We conducted a retrospective cohort study at the Persistent Physical Symptoms Research and Treatment Unit, Maudsley Hospital, between 2014 and 2019. The primary outcome was sleep quality and other sleep parameters assessed by the Pittsburgh Sleep Quality Index (PSQI). The secondary assessments comprised the Chalder Fatigue Questionnaire (CFS), the Work and Socia …

28.08.2026journal-article

Journal of Clinical Medicine

Comparison of Rehabilitation Outcomes Between Surgical and Conservative Treatments for Incomplete Intertrochanteric Proximal Femur Fractures—A Retrospective Cohort Study

Cheuk Kin Kwan, Yu Hei Choi, Rossetti Hiu Yin Lam, Richard Ku, Tsz Hang Ma, Wing Hong Liu, Wing Hoi Cheung, Chaoran Liu, Sheung Wai Law, Ronald Man Yeung Wong

Background/Objectives: Incomplete intertrochanteric proximal femur fractures pose a management dilemma regarding the choice between surgery and conservative care. This study compared radiographic and functional outcomes between surgical fixation and conservative treatment and evaluated whether immediate full weight-bearing (FWB) can be performed by conservatively managed patients. Methods: This is a retrospective cohort study of consecutive patients aged ≥60 who presented with MRI-confirmed incomplete intertrochant …

28.08.2026journal-article

Current Signal Transduction Therapy

Molecular Insights into Signalling Pathways and Therapeutic Monitoring of Chronic Low-grade Inflammation-associated Obesity

Nidhi Singh, Avijit Mazumder, Priyanka Bansal

Introduction: Obesity has emerged as a major global public health concern. It is a multifactorial condition encompassing genetic, environmental, socioeconomic, and psychosocial factors. This narrative review aims to highlight the key pathophysiological processes associated with chronic low-grade inflammation (CLGI) in obesity. Methods: Data collection was performed using the PubMed, Scopus, Web of Science, and Google Scholar databases, using the search terms “chronic low-grade inflammation”, “pathophysiology of obe …

28.08.2026journal-article

Frontiers in Immunology

Recognition and management of early complications in CAR-T cell therapy and virus-specific T-lymphocyte therapy: a practical clinical reference

Marek Ussowicz, Ewa Jakubczyk, Tomasz Wróbel, Anna Czyż

Background Cellular immunotherapies—including chimeric antigen receptor T-cell (CAR-T) therapies and adoptive transfer of virus-specific T lymphocytes (VSTs) — have transformed the treatment of refractory hematological malignancies and post-transplant infectious complications. Eight products are currently authorized by the European Medicines Agency, encompassing seven autologous CAR-T products targeting CD19 or BCMA and tabelecleucel (Ebvallo), the first approved allogeneic off-the-shelf EBV-specific T-cell product …

28.08.2026journal-article

Malignant tumours

The Geriatric-8 (G8) screening questionnaire as a predictor of anticancer therapy toxicity in elderly patients: a comprehensive analysis of current data

A. B. Elmurzaev, I. N. Danilov, I. V. Rykov, G. A. Chizh, T. P. Nikitina, S. O. Kuzin, O. S. Lokotosh, V. A. Mirgorodskaya

Introduction. Treatment of elderly cancer patients is challenging due to high risk of adverse events. Comprehensive Geriatric Assessment (CGA) is the gold standard but time-consuming. The G8 screening tool rapidly identifies patients requiring CGA. Aim. To summarize current evidence on the predictive value of the G8 for chemotherapy toxicity, assess its diagnostic accuracy, compare it with other geriatric scales, and evaluate its applicability in the Russian population. Materials and methods . A systematic search o …

28.08.2026journal-article

International Journal of Molecular Sciences

Magnetic Mitohormesis as a Potential Non-Invasive Restorative Therapy for X-Linked Muscular Dystrophies

Jan Nikolas Iversen, Alfredo Franco-Obregón

Duchenne and Becker X-linked muscular dystrophies are no longer viewed as disorders arising solely from passive sarcolemmal fragility but as diseases that progress because of disruption of cellular mechanotransduction. Evidence is accumulating that the gating of TRPC1 and TRPC3 mechanosensitive channels is altered in the absence of dystrophin, resulting in a breakdown of sarcoplasmic calcium homeostasis and preferential loss of type II glycolytic muscle fibres, while type I oxidative fibres are spared. TRPC1-mediat …

28.08.2026journal-article

Journal of Endovascular Therapy

Endovascular Aspiration Thrombectomy of the Superior Mesenteric Artery for Treatment of Acute Mesenteric Ischemia: Results From the ENDO-SMA2MI Registry

Mario D’Oria, Sandro Lepidi, Paolo Spath, Mauro Gargiulo, Ciro Ferrer, Gioele Simonte, Stefano Gennai, Francesco Giurazza, Anna Maria Ierardi, Diego Visconti, Reinhold Perkmann, Raffaello Bellosta, Nicolò De Manzini, Cristiano Calvagna, Alan Biloslavo

Background/Objective. Acute mesenteric ischaemia (AMI) is a multidisciplinary emergency, requiring the involvement of different medical specialties for successful management. Endovascular aspiration thrombectomy (EAT) has entered the field leading to the possibility of treating acute arterial occlusions with a minimally invasive approach. The aim of the study was to provide contemporary data on results after use of EAT in AMI patients. Methods. The study was a retrospective, observational, multicentre study conduct …

28.08.2026journal-article

International Journal of Public Health and Medical Research

Study on the Effect of Scaffold Carriers on Tissue Repair and Rehabilitation in Cellular Environment

Yuwei Jiang

Scaffold carriers are three dimensional porous biomaterial structures that provide structural support, metabolic signalling and an appropriate cellular environment for tissue regeneration. This article covers the effects of scaffold carrier mechanisms on tissue healing and rehabilitation in three key tissue systems: bone and cartilage, skin and soft tissue and neural tissue. This review integrates principles of extracellular matrix (ECM) biomimicry, scaffold material classification frameworks and cell-scaffold mech …

28.08.2026journal-article

International Journal of Molecular Sciences

Cell Membrane-Coated Biomimetic Nanocarriers for Plaque-Targeted Atherosclerosis Therapy: Molecular Mechanisms, Inflammatory Microenvironments, and Translational Challenges

Ruiyu Zhang, Xujing Yuan, Jinpeng Sun, Yumiao Wei

Atherosclerosis (AS) is a lipid-driven chronic inflammatory disease and the principal pathological basis of coronary artery disease, ischemic stroke, and peripheral artery disease. Despite advances in lipid-lowering, antiplatelet, anti-inflammatory, and revascularization strategies, current treatments do not selectively modulate the heterogeneous cellular and inflammatory microenvironments within individual plaques. Cell membrane-coated nanoparticles (CMNs) have therefore emerged as biomimetic delivery platforms th …

28.08.2026journal-article

Respirology Case Reports

Long‐Term Recurrence‐Free Outcome After Doxycycline Pleurodesis With Pulmonary Rehabilitation and Nutritional Support in an Underweight Patient With COPD : A Case Report

Kemas Rakhmat Notariza, Prasenohadi Pradono, Siti Chandra Widjanantie, Elfina Rachmi, Agus Dwi Susanto

ABSTRACT Secondary spontaneous pneumothorax (SSP), a complication of chronic obstructive pulmonary disease (COPD), recurs more frequently in underweight patients. This case report describes a 63‐year‐old malnourished man with COPD presenting with recurrent left‐sided SSP shortly after hospital discharge for a previous episode. Following chest tube reinsertion and complete lung re‐expansion, chemical pleurodesis was performed using 1000 mg doxycycline in saline. Transient pleuritic pain was controlled with intraveno …

28.08.2026journal-article

Recent Patents on Nanotechnology

Chitosan-functionalized PLGA Nanoparticles: Exploring Recent Patents, Advanced Strategies for Controlled and Targeted Anticancer Therapy

Madhusudan Maity, Niranjan Panda, Subas Chandra Dinda, Bikash Ranjan Jena, Parameswar Patra, Chinmaya Keshari Sahoo

Introduction: Recent advances in the field of nanotechnology have accelerated the development of polymeric nanocarriers for cancer therapy, enabling high precision and improved therapeutic efficiency. Among these, poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) have gained significant attention, as PLGA is a U.S. FDA-approved polymer for various biomedical applications. Methods: PLGA has several important properties, including biodegradability, biocompatibility, sustained drug-release properties, and minim …