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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Frontiers in Public Health

Fitness for work and the aging workforce: medical assessment as a de facto mechanism of retirement in the United Kingdom after the abolition of the default retirement age

Alida Langlois

Background Fitness for work is the judgement that a person is medically able to perform a role safely. This review considers the concept to have been shaped for a younger workforce expected to leave employment at a fixed retirement age. As populations have aged and mandatory retirement ages have been abolished, it is the instrument that remains available for questions it was not designed to answer. Methods This review traces the origins of the concept and examines what fitness for work means when applied to an agin …

03.09.2026journal-article

European Review of Aging and Physical Activity

Predictive value of physical activity and walking time for dual cognitive-physical decline: a multinational cohort study using temporal deep learning and explainable AI

Zhenhao Lin, Haonan Liu, Young-Je Sim, Dong Li, Zhonghua Sun, Jingbo Zhang, Yuwen ShangGuan, Litao Yan

Abstract Objective To develop an interpretable deep-learning framework to identify risk factors for dual cognitive-physical decline in older adults and evaluate the impact of physical activity (PA) on functional trajectories. Methods Using HRS ( n = 11,574) for discovery and ELSA ( n = 3,810) for external validation, we employed a Temporal Attention Network (TAN) to screen 15 core variables. Six conventional machine-learning algorithms and TAN were compared, with SHAP used to interpret the best-performing model. PA …

03.09.2026journal-article

Journal of Human Hypertension

Effects of combined exercise training with or without nutritional counseling on cardiovascular risk factors in older adults with hypertension: a pragmatic randomized trial

Vinícius Mallmann Schneider, Laura de Lima Silva, Gabriel Carvalho, Gabriel Lemes, Dalva Muniz Pereira, Rodrigo Ferrari

Abstract High blood pressure and elevated glycemia increase cardiovascular risk in older adults. Physical activity and diet are cornerstone non-pharmacological strategies to manage these risk factors. However, interventions in community settings focusing on the combination of exercise and nutrition are scarce. This pragmatic randomized controlled trial compared combined exercise training with versus without nutritional counseling on fasting blood glucose (primary outcome), blood pressure, body composition, and card …

03.09.2026journal-article

PLOS Global Public Health

The impact of social protection interventions on treatment and socioeconomic outcomes of tuberculosis-affected people and households in low income, high burden settings: A systematic review and meta-analysis

Mollie Hudson, Heather Todd, Talemwa Nalugwa, Ann Schraufnagel, Canice Christian, Delia Boccia, Tom Wingfield, Priya B. Shete

Tuberculosis (TB) is the leading cause of death due to infectious disease worldwide. Social protection interventions can benefit TB-affected households. We conducted a systematic review and meta-analysis to quantify the effectiveness of social protection on TB treatment and socioeconomic outcomes. We identified articles published from January 2012 to December 2025 by searching PubMed (includes MEDLINE), Embase, and Web of Science. We included studies that described at least one social protection intervention and re …

03.09.2026journal-article

PLOS One

‘My dog is my life’: One Health approaches to healthcare for people and their companion animals experiencing homelessness in the United Kingdom

Rebekah Sullivan, Andrew Gardiner, Glen Cousquer

Around one in ten people seeking shelter from homelessness in the United Kingdom have a companion animal, most commonly a dog. Dog ownership when homeless can pose a barrier to accessing healthcare and accommodation, and may force individuals to sleep on the streets. People experiencing homelessness with a dog are therefore a stigmatised minority within a minority, often invisible to support services and hard to reach. The bond between human and canine in these situations is usually strong; the dog is often the mos …

03.09.2026journal-article

Environmental Health Perspectives

Associations of Green Space and Air Pollution Mixture with Heterogeneous Biological Aging Patterns

Guoqiang Ma, Jing Xu, Yishu Li, Yuefei Wu, Qian Li, Xuan Cao, Zitong Zhao, Jingyan Gao, Lijun Gao, Lina Yan, Xiaolin Zhang

Abstract Evidence on associations between green space, air pollution mixture, and heterogeneous biological aging patterns remains limited. We investigated the opposing effects of green space and air pollution mixture on biological aging patterns using an accelerated longitudinal design based on repeated-measures data from 11,760 adults (aged 20–65 years) in a high-pollution Chinese city. Biological age acceleration (BAA) was derived via the Klemera-Doubal method. Group-based trajectory modeling identified three sta …

03.09.2026journal-article

The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences

Association between physical activity bout length and physical functioning in older adults using absolute and relative intensity thresholds: A longitudinal cohort study

Matti Hyvärinen, Antti Löppönen, Timo Aittokoski, Soren Brage, Tomas Gonzales, Taina Rantanen, Laura Karavirta

Abstract Background Defining moderate-to-vigorous physical activity (MVPA) relative to individual capacity, instead of absolute intensity cut-points, may provide a more meaningful representation of physical activity in relation to age-related decline in physical functioning. We examined whether associations between MVPA energy expenditure (MVPAEE) and changes in physical functioning differ when MVPA is defined using absolute versus relative intensity cut-points, and whether bout length modifies these associations i …

03.09.2026journal-article

Frontiers in Endocrinology

Endocrine regulation of uromodulin in aging

Kerim Mutig, Prim B. Singh, Svetlana Lebedeva

Uromodulin (Umod) is the most abundant urinary protein produced by the thick ascending limb (TAL) and distal convoluted tubule (DCT) of the kidney. Its physiological functions range from the protection against urinary tract infections (UTIs) and prevention of urinary stones to the modulation of ion transport along the distal nephron. Apart from the apical release into urine, Umod is delivered to the renal interstitium and serum via basolateral secretion to fulfil immunoregulatory tasks. Mutations and polymorphisms …

03.09.2026journal-article

Current Issues in Sport Science (CISS)

Opportunities and challenges associated with the participation and involvement of people with disabilities in sport events

Christoph Kreinbucher-Bekerle, Sophie Tatzer

Introduction & Purpose Participation in sport events can support social inclusion and belonging, yet may be limited by accessibility, organisational, informational and social barriers (Kiuppis, 2018; Elipe-Lorenzo et al., 2025). Besides taking part as an athlete, the possibility as volunteering in events is a chance to enhance the inclusion of people with disabilities in the field of sports (Jobst & Kreinbucher-Bekerle, 2025). This ÖSG supported participatory project investigates perceivedbarriers and facilitating …

03.09.2026journal-article

Current Journal of Applied Science and Technology

Integration of Battery Aging into the Energy Management of Hybrid Vehicles

Yahouza Chaibou Chapi, Noma Talibi Soumaïla, Attoumane Kosso Mamadou Moustapha, Insa Issoufou Moussa, Issaka Ango Mahaman Noura, Boureima Seibou

Hybrid electric vehicles use coordinated thermal and electrical power sources to reduce fuel consumption, but battery ageing progressively limits the electrical contribution to propulsion. This study integrates battery ageing into the energy management of a parallel hybrid electric vehicle controlled by an equivalent consumption minimisation strategy (ECMS). The strategy prioritises the battery as the principal power source and updates the equivalence factor using battery state-of-charge feedback. Battery ageing is …

03.09.2026journal-article

Frontiers in Aging Neuroscience

Sex hormones in the nucleus incertus: a novel perspective on sex/gender differences in memory and mood dysfunction in Alzheimer’s disease

Camila de Ávila, Ayanabha Chakraborti, Andrew L. Gundlach, Lisa Y. Maeng

About 60% of the individuals living with Alzheimer’s disease (AD) in the United States are women. Increasing evidence points to a role for sex hormones, especially estrogen, in making women more vulnerable to AD than men. Several brainstem signaling pathways, as well as multiple neuropeptide modulators and their receptors, are implicated in AD pathology and therapeutic possibilities. However, there is limited research evaluating how the modulatory effects of sex hormones on mood and cognition interact with these br …

03.09.2026journal-article

Asia Pacific Economic and Management Review

People before Perimeters: Employee Awareness as the Primary Driver of Zero-Trust Architecture Adoption in Banking

Deogratius Mathew Lashayo

Financial institutions face increasing exposure to sophisticated cyber threats, prompting a shift from traditional perimeter-based security toward Zero-Trust Architecture (ZTA), a model built on continuous verification and least-privilege access. Despite growing global adoption, empirical evidence on the determinants of ZTA adoption within African, and more specifically Tanzanian, banking institutions remains scarce. This study examines the factors influencing ZTA adoption at NMB Bank PLC, Tanzania, using an extend …

03.09.2026journal-article

Energies

Nonlinear Fatigue Damage Assessment for Transformer Windings Under Thermal Aging and Repeated Short-Circuit Loading

Chunyan Zang, Peng Li, Feng Jiang, Ruijuan Tan, Ke Wang, Dandan Zhang, Peng Chen, Xiangyue Longhe

Transformer winding failures are driven by the cumulative degradation from repeated short-circuit shocks rather than a single extreme event. Current standards rely on static strength checks using as-manufactured material properties, ignoring both thermal aging and load-history effects. To address this gap, we propose a nonlinear fatigue cumulative damage framework that couples a long-term thermal-aging spectrum, converted into an equivalent aging duration and a global property correction, with a micro-spectrum of i …

03.09.2026journal-article

South Asian Journal of Cancer

AsiaPacific Geriatric Oncology Society (AGOS; virtual tumour board no 9) real world consensus for management of endometrial cancer with multiple co-morbidities and polypharmacy in the older patient

Purvish M Parikh, Nikhil Ghadyalpatil, Dharshitha Varigonda, TVSVGK Tilak, Bipinesh Sansar, Karishma De, Mosale Venkatesha Chandrakant, VenkataSampath Vankamamidi, Steve Paul Manjaly, Athika Shaik, Madhusudhan Perumandla

The AsiaPacific Geriatric Oncology Society (AGOS) conducts a monthly virtual tumour board. One of the cases discussed was a 70-year-old female with Stage IIIA endometrial cancer, multiple co-morbidities and polypharmacy. A group of experts discussed the challenges in the real world with specific reference to improving Timed Up and Go (TUG) score, managing the effect of co-morbidities, preventing risk due to drug-drug interactions and evaluating the risk of delaying anti-cancer therapy in an attempt to improve patie …

03.09.2026journal-article

Journal of Medical Internet Research

Proximal Effects of a Transdiagnostic, Ecological Momentary Intervention for Enhancing Resilience in Help-Seeking Young People (EMIcompass): Findings From a Secondary Analysis of an Exploratory Randomized Controlled Trial

Jessica Gugel, Christian Rauschenberg, Isabell Paetzold Jaehme, Anita Schick, Eva Wierzba, Dusan Hirjak, Jan Rasmus Boehnke, Benjamin Boecking, Ulrich Reininghaus

Abstract Background Ecological momentary interventions (EMIs) offer a promising strategy for targeting putative mechanisms of mental health problems by delivering real-time, tailored intervention components that adapt to person, moment, and context based on data collected using ecological momentary assessment (EMA). However, most research to date focuses on effects on distal outcomes, at the person level, whereas exploration of processes at the microlevel, that is, proximal effects of EMI components on putative mom …

03.09.2026journal-article

Journal of Midwifery & Women's Health

Characteristics Associated With Tub Entry and Birth in Water Among People Planning a Waterbirth

Emily Malloy, Amanda Luff, Jessica J.F. Kram, James Adefisoye, Marie Forgie, Valerie Oliver, MaryAnne Scherer, Cara Wolf, Devika Chakrabarti, Lisa Hanson

Introduction Waterbirth is a pain relief option and a comfort measure not widely available in US hospitals. This study presents a secondary analysis of a randomized control trial of waterbirth examining participants’ entry into the tub and final location of birth (water or non‐water) to determine characteristics associated with successful waterbirth. Methods We analyzed data from a hospital‐based waterbirth study that was conducted at a large, urban, midwestern medical center. Among those planning a waterbirth who …

03.09.2026journal-article

Eurosurveillance

First year of ongoing invasive Haemophilus influenzae type b outbreak among middle-aged people who use drugs and people who experience homelessness in Hamburg, Germany, September 2024 to August 2025

Silja Bühler, Vanessa Piechotta, Martin Noldt, Christine-Maria Hartog, Caroline Peine, Cornelius Rau, Claudia Siffczyk, Katja Kajikhina, Ole Wichmann, Iris Meier, Maja V Nielsen, Melanie Lang, Amra Arif, Emma Edel, Jennifer Gabbert, Claudia Ruscher, Alexandra von Reiswitz, Jenny Schreiber, Somayyeh Sedaghatjoo, Silver A Wolf, Torsten Semmler, Heike Claus, Viktoria Schönfeld, Thiên-Trí Lâm

We report an ongoing outbreak of invasive Haemophilus influenzae type b (Hib) disease among people who use drugs (PWUD) and people experiencing homelessness (PEH) in Hamburg, Germany. Between 1 September 2024 and 31 August 2025, 20 adult Hib cases were reported. The cases were either residents of Hamburg (16/20) or stayed in Hamburg during the exposure period (4/20). Whole genome sequencing identified a link between 18 cases (median age 50 years (range 26–77); six female, 12 male, three died). An epidemiological li …

03.09.2026journal-article

Applied Sciences

Emotional Design Strategies for Enhancing the User Experience of Hand Rehabilitation Robots for Older Adults

Yansheng Ren, Kangheui Cha, Chao Zhou

As a result of population ageing, rehabilitation assistive products for older adults increasingly need to meet long-term user requirements in terms of usability, comfort, and interactive experience. Although existing hand rehabilitation robots (HRRs) are capable of supporting hand training tasks, they still exhibit deficiencies in experience-oriented design, which in turn affect user acceptability and continued use. This study aimed to identify and prioritize user requirements for HRRs and, based on their relative …

03.09.2026journal-article

Sustainability

The Livelihood of Coastal Community People in a Changing Climate and the Possible Adaptation Strategies in Bangladesh

Md. Shamsuzzoha, Mohammad Golam Kibria, Md. Hosenuzzaman, Umma Habiba, Indrajit Pal, Sanjida Hossain Setu, Md. Anwarul Abedin

The phenomenon of climate change has exerted an escalating degree of pressure on coastal livelihoods in Bangladesh. In this region, communities find themselves confronted with a dual challenge, being exposed to both rapid-onset hazards, including cyclones, storm surges, and floods, and slow-onset stresses, such as salinity intrusion and sea-level rise. These hazards have ramifications for agriculture, aquaculture, food security, and livelihood sustainability. However, extant studies frequently examine individual ri …

03.09.2026journal-article

The International Journal of Aging and Human Development

Construction and Validation of the Gendered Ageism Scale (GAS)

Cristina Curcio, Anna Rosa Donizzetti

Population aging and increasing longevity have radically transformed social dynamics. Older women experience “double discrimination” known as gendered ageism and linked to the intersection of age and gender. Despite the relevance of this construct, no measurement scale for it currently exists. The aim of the research was to construct and validate the Gendered Ageism Scale (GAS). In a first study ( N = 410), an initial set of items was developed; factor analyses were conducted; reliability and convergent validity we …

03.09.2026journal-article

Buildings

Age-Friendly Regeneration of Historic Urban Districts: Psychological Pathways Linking Spatial Resources to Older Adults’ Walking

Jingrong Yang, Bart Julien Dewancker, Yi Yang, Chao Nai, Peng Chen

Age-friendly regeneration of historic urban districts that focuses primarily on functional conditions such as streets, facilities, and accessibility may overlook place-based resources and experiences relevant to older adults’ everyday walking. Taking the Cuihu Historic and Cultural District in Kunming, China, as a case study, this study developed a Spatial Resource Index (SRI) comprising historical spatial resources, walking support resources, public cultural resources, and restorative environmental resources. GIS- …

03.09.2026journal-article

AVANCA | CINEMA

Entre o Controle e a Ruptura: Representações acerca do Envelhecimento na Distopia do filme O Último Azul

Liliane Maria Macedo Machado, Marcus Vinicius Azevedo de Mesquita

This article analyzes Gabriel Mascaro’s film The Blue Trail (O Último Azul, 2025) through the lens of the social representations of female aging, employing an intersectional approach that articulates gender, social class, and age. The authors investigate how the film constructs its narrative within a dystopian world and challenges stereotypes traditionally associated with older women, who are often portrayed as fragile, unproductive, and socially invisible. Drawing on feminist and gender studies scholars such as Na …

03.09.2026journal-article

Dementia

“Like a Prisoner”: Stories From Evergreen Manor

Erica MacTavish, K. Aly Bailey, Kimberly J. Lopez, Sherry Dupuis

Stigmatizing accounts of dementia emphasize tragedy, constructing people living with dementia as ‘unagentic’ and ‘failed’ aging subjects, and cognitive changes as a loss of self. This stigma has significant consequences for people living with dementia in all aspects of their lives. For example, coupled with the biomedical culture in many long-term care settings, recreation and leisure is often focused on targeting therapeutic goals or managing “difficult behaviours,” rather than on life enrichment. A social citizen …

03.09.2026journal-article

Frontiers in Nutrition

Combined effects of resistant dextrin and inulin on the reduction of harmful metabolites during in vitro fecal fermentation in older adults

Kazuma Yoshida, Takeshi Matsubara, Shunsuke Morita, Yasuyuki Sakata, Hirofumi Sonoki, Kazuhiro Miyaji

Background/objectives Aging-related dysbiosis is associated with increased production of harmful gut-derived metabolites. Reducing these metabolites by modulating the gut microbiota is important for maintaining health in older adults. This study aimed to investigate whether a combination of resistant dextrin and inulin suppresses the production of harmful metabolites in the gut microbiota of older adults using in vitro fecal fermentation and a metabolomics approach. Methods Fecal samples from eight older adults wer …