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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
28.08.2026journal-article

Frontiers in Nutrition

Data-driven dietary patterns in relation to psychological distress and psychological quality of life among community-dwelling older adults in Shanghai, China: a cross-sectional study

Haonan Shi, Zuowei Wang, Jia Zhu, Miqiong Li, Wang Li, Weiyun Xu, Ziyi Sun, Cheng Chen, Chuan Zhang, Tingting Wang, Xuan Yao

Objectives: Evidence linking overall dietary patterns with psychological health in older adults remains inconsistent, particularly in urban China. We derived dietary patterns among community-dwelling older adults in Shanghai and examined their associations with multiple psychological outcomes. Methods We analyzed cross-sectional baseline data from adults aged ≥60 years recruited at two community health service centers in Shanghai. Previous-month diet was assessed using a modified quantitative 25-item food-frequency …

28.08.2026journal-article

Foods

Six Bioactive Small Molecules from Tremella fuciformis with Potential for Healthy Aging

Feifei Wang, Yuxuan Duan, Ziying Cai, Shidong Lin, Lingjun Yu, Yongbiao Zheng

Six representative small-molecule constituents were isolated and structurally characterized from the edible mushroom Tremella fuciformis: cis-oleic acid (1), 1-oleoylglycerol (2), cerevisterol (3), a cerebroside (4), trans-homoaconitic acid (5), and uridine (6). Compound 5, a tricarboxylic acid derivative, is reported for the first time as abundantly accumulated in this fungus. Aging-relevant assays showed that 1 potently inhibited α-glucosidase (IC50 = 0.02 mM, surpassing acarbose) and moderately inhibited acetylc …

28.08.2026journal-article

Health Medicine and Therapeutics

Cultural Sensitivity in Geriatric Care: An Exploratory Mixed-Methods Study

Sen Yang, Minerva De Ala

The global demographic shift towards an aging population underscores the critical need for effective and culturally appropriate geriatric care. Existing healthcare models frequently overlook the diverse cultural backgrounds of older adults, potentially leading to communication barriers, patient dissatisfaction, and suboptimal health outcomes. This research investigates how cultural beliefs and practices shape the experiences and preferences of older adults receiving geriatric care, and examines the implications for …

28.08.2026journal-article

Working with Older People

AI acceptance and trust among family caregivers as surrogate decision-makers

Suraj Kumar, Lasya KR, Dara Vijaya Lakshmi, Sangeetha R, Shrinivas K, Rashmi BH

Purpose This study aims to explore the joint influence of all four factors (performance expectancy, perceived risk, facilitating conditions and trust in AI), along with the remaining two factors (behavioral intention and caregiver health literacy), on caregiver AI acceptance. Design/methodology/approach To test both net-effect paths and configurational pathways, a cross-sectional survey of family caregivers was analyzed using partial least squares structural equation modeling and fuzzy-set qualitative comparative a …

28.08.2026journal-article

Frontiers in Surgery

Four eras of geriatric femoral neck fracture surgery: a bibliometric analysis of half-century research evolution and emerging frontiers

Da-Wei Zhang, Hai-Ting Hong, Liang-He Lin, Zhen-Xin Fu

Background The core clinical decision in geriatric femoral neck fracture—internal fixation vs. arthroplasty—has remained contested for half a century. Although landmark trials such as FAITH, HEALTH, and WHiTE 5 have profoundly reshaped clinical practice, no bibliometric study has systematically mapped the complete research architecture and knowledge evolution trajectory of this field from 1975 to the present. This study aimed to characterize the global research landscape and knowledge evolution of surgical treatmen …

28.08.2026journal-article

Journal of Clinical Medicine

Visual and Semiquantitative Assessment of 123I-Ioflupane SPECT in Probable Dementia with Lewy Bodies and Its Association with Autonomic Dysfunction: A Retrospective Study

Tahmina Arslan, Recep Bekiş, Mehmet Selman Ontan, Ahmet Turan Isik

Background/Objectives: Dementia with Lewy bodies (DLB) is a clinically heterogeneous neurodegenerative disorder characterized by cognitive, neuropsychiatric, motor, and autonomic manifestations. Reduced striatal dopamine transporter availability on 123I-ioflupane single-photon emission computed tomography (SPECT) is an established indicative biomarker of DLB. However, the associations among expert visual interpretation, regional semiquantitative dopamine transporter measurements, autonomic manifestations, and demen …

28.08.2026journal-article

Journal of Nondestructive Evaluation, Diagnostics and Prognostics of Engineering Systems

A Method for Assessing the X-Ray Equipment Aging Factor to Correct the Film Exposure Time

Héctor Salazar-Fonseca, Kevin Marroquín, Luis Salazar-Fonseca, Santiago Camacho, Veronica Sotomayor, Wilson Guachamín-Acero

Abstract Good-quality radiographic images are essential for accurate medical diagnosis and reliable defect detection in welds. As X-ray equipment ages, the radiographic spatial resolution decreases because the focal spot area (FSA) enlarges, increasing geometric unsharpness and degrading image quality. To compensate for this degradation, operators often increase the film exposure time based on personal experience. This article introduces a method for the systematic assessment of a dimensionless aging correction fac …

28.08.2026journal-article

The Gerontologist

“Not for Our Age”: Self-Ageism in Older Adults’ Dementia Screening Decision

Jiahui Jin, Benjamin Junting Li, Yin-Leng Theng

Abstract Background and Objectives To explore age-specific insights into how older adults understand and decide about health screening, using dementia screening as a critical case. Research Design and Methods Participants were 44 community-dwelling older adults in Singapore (ages 64–87). Six focus group discussions (FGDs) were conducted. Audio recordings were transcribed, standardized into English, and verified through independent bilingual checks. Data were analyzed using a hybrid inductive–deductive thematic anal …

28.08.2026journal-article

The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences

Unequal Embodiment: Racial and Ethnic Heterogeneity in the Predictors and Age-Related Health Outcomes Associated with Accelerated Biological Aging

Mariela Villalba Madrid, Francisco Ríos Casas, Mateo P Farina

Abstract Background This study investigates whether life-course socioeconomic exposures are similarly associated with accelerated biological aging across racial and ethnic groups, and whether accelerated biological aging predicts health outcomes equivalently across groups. Methods Data came from the Health and Retirement Study (2016-2022). Accelerated biological age was derived from 22 blood-based biomarkers from the 2016 Venous Blood Study. We used linear regression models with interactions between race/ethnicity …

28.08.2026journal-article

Cancer Medicine

Type 2 Diabetes Risk Among Older Asian, Native Hawaiian and Pacific Islander Patients With Head and Neck Cancer in the United States

Chun‐Pin Esther Chang, Sarah M. Drejet, Jason P. Hunt, Marcus Monroe, Mia Hashibe

ABSTRACT Diabetes is one of the most prevalent comorbidities among patients with head and neck cancer (HNC), and its burden is disproportionately higher in Asian American, Native Hawaiian, and Pacific Islander (ANHPI) populations. However, the incidence and risk factors for diabetes among ANHPI HNC patients remain unknown. The aim of our study was to examine the incidence and risk factors of developing Type 2 diabetes among older (≥ 66 years of age) ANHPI HNC patients in the United States, as well as differences ac …

28.08.2026journal-article

Medicine

Sex‑specific associations between multiple hormone axes and dynapenic obesity in middle‑aged and older patients with type 2 diabetes

Di Yu, Qin Ou, Bo Xie, Yinghao Li, Kun Liao, Rong Li, Mei Mei, Bo Zhou

Accumulating evidence indicates that hormones play a critical role in the pathogenesis of dynapenic obesity (DO), although the precise relationships and underlying mechanisms remain elusive. This study aimed to investigate sex-stratified associations between multiple hormones and prevalence of DO in type 2 diabetes mellitus (T2DM) populations. In this cross-sectional study of 557 T2DM patients, body composition was assessed by dual-energy X-ray absorptiometry, and hormones from pituitary-target gland axes and the v …

28.08.2026journal-article

Journal of Innovations in Materials and Manufacturing Engineering

Influence of Heat Treatment and Thermal Aging on the Fatigue Performance of LPBF Fabricated AlSi10Mg Alloy

Edel Arrieta, Luis A. Marquez, Lawrence E. Murr, Diego A. Ariza, Mark Benedict, Jason Thomas, James Carney, Francisco Medina

This investigation explores fatigue performance of laser powder bed fusion (LPBF)-fabricated AlSi10Mg alloy subjected to various post-processing treatments: stress relief (SR), Hot Isostatic Pressing (HIP), and HIP + T6, all followed by prolonged thermal aging at 177 °C for up to 1000 h. Microstructural evolution, hardness, density, and uniaxial fatigue performance, including SEM fractography, were examined to recommend practical service life thresholds. Microstructural analysis confirmed that HIP and HIP + T6 trea …

28.08.2026journal-article

Multiple Sclerosis Journal

Affective reserve in older adults with and without multiple sclerosis: A residual-based approach

Elizabeth S. Gromisch, Frederick W. Foley, Mark E. Wagshul, Roee Holtzer

Background: The concept of affective reserve has been proposed, but not operationalized, as a buffer designed to regulate mood and behavior in response to adverse events. This study derived a residual-based metric of affective reserve and evaluated whether it mediated associations between having multiple sclerosis and subjective well-being in older adults. Methods: Sociodemographics and brain pathology metrics were regressed against a composite mood, extraversion, and consciousness variable to derive affective rese …

27.08.2026journal-article

The Journal of Chemical Physics

Physical aging and molecular dynamics in poly(4-alkylstyrene)

Koji Fukao, Akira Goda, Airi Kawano, Ryo Ueyoshi, Kohei Nishi, Ryo Iguchi, Jun Yoshioka, Satoru Matsushima, Saya Yamada, Atsushi Takano

To elucidate the relationship between physical aging and molecular dynamics in poly(4-alkylstyrene), three types of measurements were performed: capacitive dilatometry (CD), differential scanning calorimetry (DSC), and dielectric relaxation spectroscopy (DRS). Using CD and DSC, we successfully observed volume and enthalpy relaxation processes during isothermal aging in the glassy state. DRS measurements revealed four dynamical processes: the α-process, β-process, γ-process, and a slower process, in addition to the …

27.08.2026journal-article

Eng

Effect of Different Metal Oxide/Montmorillonite Nanocomposites on Aging Resistance of SBS-Modified Asphalt

Guangye Si, Genfu Liang, Gen Li, Chongzheng Zhu

To improve the aging resistance of SBS-modified asphalt (SBSMA), this study prepared two metal oxide/montmorillonite nanocomposites, TiO2/montmorillonite (TM) and CeO2/montmorillonite (CM), and investigated their effects on the rheological properties and microstructure of SBSMA before and after long-term aging. The performance differences between the two nanocomposites under different aging modes were also compared. Conventional physical property tests, dynamic shear rheometer tests (temperature sweep and linear am …

27.08.2026journal-article

Frontiers in Neuroinformatics

Interpretable AI for neural signal decoding in dementia: an EEG ensemble approach to differential diagnosis

Fawad Muhammad, Irfan Ahmed Usmani, Muhammad Aamir, Mai Alduailij, Mehrez Marzougui, Rab Nawaz

Introduction The differential diagnosis between Alzheimer’s disease (AD) and frontotemporal dementia (FTD) presents a significant clinical challenge due to overlapping early-stage symptom profiles. Conventional resting-state EEG provides limited sensitivity to the impaired neural plasticity and lateralized cortical degeneration frequently observed in FTD. Methods We developed a domain-informed heterogeneous ensemble framework incorporating dynamic neural reactivity and hemispheric asymmetry metrics from 19-channel …

27.08.2026journal-article

Frontiers in Aging

Grip strength as a systems biomarker of aging: neuromuscular junction constraints and biomarker decoupling in gene therapy

Patrick E. Sewell, Christopher Jensen

Grip strength has emerged as one of the most robust predictors of mortality, disability and healthspan across populations. Yet its predictive validity rests on an often-unstated assumption: that grip strength serves as a passive readout of systemic biological integrity rather than an isolated measure of forearm function. Here we propose that grip strength derives its prognostic power from its position as a convergent output of multiple aging-sensitive physiological systems—including neuromuscular, vascular, metabol …

27.08.2026journal-article

TEM Journal

Application of an Electronic Cane for Blind People - Analysis and Evaluation

Denitsa Dimitrova, Aneliya Manukova, Iovan Stoev

This study examines various methods, criteria, and technological approaches used to evaluate parameters associated with the mobility of individuals with disabilities, with particular emphasis on the development of an electronic guidance and monitoring system integrated into a cane for visually impaired users. The proposed engineering solution includes an electronic module based on an ESP32-S3 microcontroller, tested in laboratory and real conditions. Methods for determining distance and signal processing have been …

27.08.2026journal-article

Journal of Ambulatory Care Management

Formative Evaluation of a Pharmacist-Led Area Agency on Aging Community Care Transition Initiative: A Qualitative Interview Study From Staff Perspectives

Hao-Ping Chiang, Brigid Rowell, Karen B. Farris, Nathaniel Bergman, Antoinette B. Coe

Objectives: The Michigan Region VII Area Agency on Aging (AAA) conducted a community care transition initiative (CCTI) for rural, low-income older adults to reduce hospital readmission rates. The AAA CCTI included a community health worker (CHW) home visit, pharmacist telehealth comprehensive medication review, and follow-up after discharge. Our study aimed to conduct a formative evaluation of the AAA CCTI to identify areas for program refinement. Identified strategies for program refinement add to the development, …

27.08.2026journal-article

Inquiry@Queen's Undergraduate Research Conference Proceedings

Music and Movement Program for Older Adults in a Hospital Setting

Olivia Pellarin

Background: The SWAY program was a pilot project designed to explore the benefits and feasibility of implementing an art-based program in a hospital setting to support selfhood and well-being among older adults. Due to the rapid aging population in Canada, it is crucial to identify effective approaches to support the well-being of older adults. Research in Community Arts consistently highlights the positive outcomes of singing and movement-based programs for older adults. Specifically, singing and dancing have been …

27.08.2026journal-article

Healthcare

Effects of a Nurse-Led Web-Based Fall Prevention Program on Fall Risk and Fear of Falling Among Older Adults: A Randomized Controlled Trial

Nur Sema Kaynar Demirel, Selda Secginli

Objectives: This study aimed to evaluate the effects of a nurse-led Web-Based Fall Prevention Program (Web-FPP) on fall risk, fear of falling, fall-preventive behaviors, and the number of falls among community-dwelling older adults aged 65 years and older. Methods: A single-blind, stratified randomized controlled trial was conducted with 72 older adults (36 intervention, 36 control) in Türkiye. The Web-FPP was delivered over six weeks and included educational content, video-based exercises, and home safety strategi …

27.08.2026journal-article

HIV Medicine

Wellbeing of trans and gender‐diverse people with HIV in the United Kingdom: Results from Positive Voices 2022

H. Kitt, C. Kelly, A. Aghaizu, M. Ross, F. C. Lampe, C. J. Smith, V. Martin, C. Humphreys, A. Brown, A. Sparrowhawk, M. Kall, J. Sewell, E. Wainwright, V. Delpech, G. Davis, A. Farah, A. Fasanya, A. J. Rodger, T. Đuretić, PV2022 Study Group

Abstract Objectives This national cross‐sectional observational study aimed to assess mental health, quality of life, supportive network, experiences of HIV‐related stigma in healthcare and unmet service need among trans and gender‐diverse people with HIV, compared to cisgender people with HIV. Methods Positive Voices 2022 is a questionnaire survey of people accessing HIV care in England, Scotland and Wales carried out in 2022 and 2023 that included measures of depression and anxiety symptoms and suicidal ideation …

27.08.2026journal-article

Astronomy & Astrophysics

Radio spectral properties and aging of two tailed radio galaxies in a galaxy group at z=0.35

P. Vulić, V. Smolčić, A. Finoguenov, G. Gozaliasl, H.S.B. Algera, I. Delvecchio

We present a study of two tailed radio galaxies located in the core of a massive, dynamically young galaxy group, previously identified as an early group-group merger. Using broadband VLA 3 GHz and 1.4 GHz, MeerKAT 1.35 GHz, and GMRT 610 MHz and 325 MHz observations, we investigate the radio spectral properties as well as the spectral and dynamical ages of both sources. The radio morphologies show clear evidence of an interaction with the intragroup medium (IGM). One galaxy is a wide-angle tail (WAT) source with we …

27.08.2026journal-article

Lechaschi Vrach

Senolytics: a new perspective on connective tissue aging prevention and osteoarthritis therapy

O.A. Shavlovskaya

Background. Aging processes affecting all organs and systems of the body, including connective tissue, supporting joints and spine, significantly reduce the quality of life of patients of elderly and senile age. Senescent cells are resistant to apoptosis, they have increased metabolic activity, without suppression of which the accumulation of senescent cells occurs, and leads to chronic inflammation and connective tissue dysfunction. Senescent cells have a powerful senescence-associated secretory phenotype, which c …