Natural Resources for Human Health
Isoflavones in the Prevention of Photoaging: Antioxidant and Collagen-Regulating Mechanisms—An Integrative Review
Skin aging due to ultraviolet (UV) light exposure, known as photoaging, is a form of extrinsic aging characterized by increased oxidative stress, collagen degradation, and structural changes in the dermis. Chronic UV exposure triggers the formation of reactive oxygen species (ROS), activation of matrix metalloproteinases (MMPs), inflammation, and decreased tissue regeneration. Soy isoflavones, as natural phytoestrogens, offer potential as antiphotoaging agents through potent antioxidant mechanisms and stimulation o …