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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
31.08.2026journal-article

International Journal of Science and Research Archive

FACTORS ASSOCIATED WITH ADHERENCE TO ANTIRETROVIRAL THERAPY AMONG THE YOUTH RECEIVING LONG-TERM ART IN SELECTED HEALTH CENTRE IVS IN ISINGIRO DISTRICT, UGANDA

Kalega William, Otwine Tweheyo Anne, Jordan Amanyire

Introduction: Optimal adherence to antiretroviral therapy (ART) is essential for viral suppression, yet the factors driving adherence among youth in rural Ugandan settings remain incompletely documented. This article, drawn from a wider study, examined the factors associated with ART adherence among youth receiving long-term ART in selected Health Centre IVs in Isingiro District, Uganda. Methods: A cross-sectional design employing a mixed-methods approach was used. Quantitative data were collected from 243 youths a …

31.08.2026journal-article

AIDS

LDL-C target achievement in people living with HIV: impact of combination lipid-lowering therapy. A retrospective cohort analysis

Marcella Manicardi, Jovana Milic, Giuseppe Esposito, Marianna Menozzi, Giuseppe Mancini, Gian Luca Cuomo, Lorenzo Benassi, Elisabetta Delmonte, Severino Ambrosio, Cristina Mussini, Giuseppe Boriani, Giovanni Guaraldi

Background: Real-world low-density lipoprotein cholesterol (LDL-C) target attainment remains low in people with HIV (PWH). Updated ESC/EAS 2025 guidelines underscore the need to reassess treatment patterns in clinical practice. Methods: Retrospective observational longitudinal study including PWH ≥40 years, evaluated twice between 2020 and 2025 at the Modena HIV Metabolic Clinic, with complete laboratory and clinical follow-up data. Objective was to evaluate the real-world use and effectiveness of different lipid-l …

31.08.2026journal-article

Bioinformation

Photodynamic therapy response of Filifactor alocis and Fretibacterium fastidiosum: Diabetic versus nondiabetic chronic periodontitis patients

Jitendra Jasutkar

Chronic generalized periodontitis is associated with emerging periodontal pathogens, posing greater challenges for microbial control in patients with diabetes. Therefore, it is of interest to evaluate the prevalence of Filifactor alocis and Fretibacterium fastidiosum in healthy individuals and diabetic and non-diabetic patients with chronic generalized periodontitis. Thirty patients underwent clinical and microbiological assessment before and after scaling and root planing with adjunctive photodynamic therapy. Adju …

31.08.2026journal-article

The Indonesian Journal of Occupational Safety and Health

Communication, Procedures, and Risk Perception on the Driving Behavior of Forklift Operators

Dr. Dewi Kurniasih, S.KM., M.Kes, Ahmad Fatihul Azzam, Farizi Rachman, Desi Tricahyaningati

Introduction: Forklifts play an important part in supporting loading and unloading operations within the fleet. Based on the company’s 2024 near-miss records, they account for the highest proportion of incidents, with 9 near misses—representing 69%—mainly attributed to human error. These human errors among forklift operators are categorized as unsafe behaviors. Methods: The goals of this study is to present an analysis of the impact of communication and procedures, as well as risk perception, on driver behavior; to …

31.08.2026journal-article

Current Cancer Therapy Reviews

Retraction Notice to "Emerging Translational Approaches for Lung Cancer Therapeutics"

Ishpreet Singh Bedi, Pushpendra Jain

It has come to the publisher’s attention that an identical version of this article was previously published in the International Journal of All Research Education & Scientific Methods (IJARESM) under the following link: "https://www.ijaresm.com/ uploaded_files/document_file/Jain_Pk_2tsi0.pdf". As duplicate publication violates ethical publishing standards, the publisher has informed the authors and has decided to retract the article from Current Cancer Therapy Reviews. Bentham Science apologizes to the readers of t …

31.08.2026journal-article

Jounral of Educational Therapist

The Effects of Generative AI-based Gratitude Journaling on Adolescents’ Life Satisfaction, School Satisfaction, Self-esteem, and Anger

THE KOREAN SOCIETY OF EDUCATIONAL THERAPY, Chae-hee Lee, Su-Keun Yu, Juyeol Ryu, Na Young Shin

This study investigated the effects of generative AI-based school-life gratitude journaling on life satisfaction, school-life satisfaction, self-esteem, and anger among middle school students. Participants in the gratitude journaling group (N = 23) recorded at least three things they were grateful for regarding their school life using a generative AI application every weekday afternoon for four weeks. The wait-list control group (N = 26) received no intervention during the study period. All participants completed t …

31.08.2026journal-article

Physiotherapy Canada

An Environmental Scan of Canadian Physiotherapy Dry Needling Regulations

Nadine Crocker, Eric Parent

Abstract Purpose: Dry needling (DN) regulations among the Canadian physiotherapy colleges were compiled to make recommendations toward a national guideline. Method: DN regulatory data extracted from regulatory body websites using an environmental scan framework was checked by an independent reviewer. Colleges were contacted to fill gaps identified from the web. Extracted content was compared to recommendations from two Canadian DN reviews to identify gaps in regulation. Results: DN regulation is done through legisl …

31.08.2026journal-article

Physiotherapy Canada

Ankle Muscle Power and Balance Performance in Older Adults

Dominique Arsenault, Tanya D. Ivanova, S. Jayne Garland

Abstract Purpose: This cross-sectional descriptive study sought to determine the influence of ankle power on balance performance. Method: Twenty healthy older adults (≥ 70 years; 11 men, 9 women; mean age of 76.6 [SD 5.5] years) with no prior debilitating injuries, neurological disorders, or respiratory diseases participated. Ambulatory balance was assessed using the Community Balance and Mobility Scale (CB&M, out of 96) – a performance-based functional outcome measure. Average power about the ankle joint was measu …

31.08.2026journal-article

Ophthalmic Surgery, Lasers and Imaging Retina

Effect of Hormone Replacement Therapy on Risk of Age-related Macular Degeneration Among an Aggregate Health Record Cohort

Charles W. Guo, Alison H. Zhao, David Kaelber, Rishi P. Singh, Katherine E. Talcott

Background and Objective: Estrogen in hormone replacement therapy (HRT) exerts anti-inflammatory effects believed to oppose age-related macular degeneration (AMD) pathogenesis, but whether HRT can be protective against AMD is contested. The aim of the study was to evaluate the association between HRT use and the risk of development and progression of AMD in postmenopausal women. Patients and Methods: This was a retrospective cohort study utilizing ICD-10 codes for HRT usage and rates of AMD development and progress …

31.08.2026journal-article

American Journal of Speech-Language Pathology

An Individualized Approach to Augmentative and Alternative Communication for Cortical Visual Impairment: One Family's Progression Toward an Accessible Language System

Tara V. McCarty, Lynn Elko, Melanie Cozad, Dawn J. Sowers, Krista Wilkinson

Purpose: Speech-language pathologists report a desire for guidance to develop and maintain augmentative and alternative communication (AAC) supports that are customized and visually accessible for individuals with cortical visual impairment (CVI; Boster et al., 2021). In 2023, Wilkinson et al. introduced the “CVI/AAC Framework” that offered initial evidence-based considerations and data collection prompts to address this clinical challenge. The current article was written to illustrate the process of the clinical a …

31.08.2026journal-article

Journal of Speech, Language, and Hearing Research

Respiratory–Swallow Training in Head and Neck Cancer: Impact on Swallowing Safety and Efficiency

Bonnie Martin-Harris, Kate Davidson, David McFarland

Purpose: This review article provides a programmatic translational synthesis of a research program investigating respiratory–swallow coordination as a modifiable physiologic target underlying swallowing impairment and safety, with a focus on individuals treated for head and neck cancer (HNC). The purpose is to synthesize physiologic evidence, clinical trial outcomes, and translational advances supporting respiratory–swallow training (RST) as a mechanism-based intervention. Method: Evidence is drawn from a series of …

31.08.2026journal-article

Advanced Functional Materials

Transdermal STING Degradation Reprograms Innate‐Adaptive Immunity Crosstalk for Relapse‐Free Psoriasis and Comorbid Arthritis Therapy

Mengchao Ding, Zhenhai Pan, Ihsan Ullah, Ye Liu, Songke Shen, Mohamed E. El‐Khouly, Youyong Yuan

ABSTRACT Psoriasis is a chronic inflammatory disorder in which current therapies provide only transient symptomatic relief by suppressing pathogenic immune responses, while the restoration of immune homeostasis and prevention of relapse or comorbid arthritis remain unaddressed. Here, we present a microneedle‐based transdermal platform incorporating reactive oxygen species (ROS)‐responsive self‐immolative polymers (SIPs) to encapsulate a proteolysis‐targeting chimera (PROTAC) for selective degradation of stimulator …

31.08.2026journal-article

Laser Therapy

Fractional picosecond laser-induced optical breakdown in dermatology: from controlled microinjury and molecular repair pathways to clinical endpoints and post-procedural care

Stefan Bigge, Bianca Bigge

Fractional picosecond lasers have expanded the clinical use of ultrashort-pulse devices from tattoo and pigment removal to non-ablative rejuvenation, scar remodeling, enlarged pores, dyschromia and selected photoaging indications. Their distinctive tissue effect is not conventional fractional coagulation or ablation, but focal photomechanical disruption mediated by laser-induced optical breakdown (LIOB) and associated laser-induced cavitation (LIC), with vacuolization in epidermal and dermal tissue planes. This rev …

31.08.2026journal-article

Stem Cell Research & Therapy

Dual properties of PEGDA-GelMA scaffold: good long-term cerebral biocompatibility but limited potential for brain regeneration

Maylis Combeau, Vincent Lanternier, Adrien Brilhault, Julien Clauzel, Lorenne Robert, Nina Colitti, Melissa Parny, Carla Cirillo, Isabelle Raymond-Letron, Franck Desmoulin, Isabelle Loubinoux

Abstract Background Acute brain injuries pose a significant clinical challenge, as current therapeutic strategies are insufficient to promote tissue regeneration or fully restore lost neurological functions. In this context, biomaterials have shown promise in promoting tissue repair. Methods This study introduces an innovative strategy involving the 3D Digital Light Processing (DLP) printing of a degradable scaffold composed of polyethylene-glycol diacrylate (PEGDA) and gelatin methacryloyl (GelMA). The neuro-impla …

31.08.2026journal-article

Archiv Euromedica

BIOLOGIC AGENTS AND CAR T-CELL THERAPY IN SYSTEMIC LUPUS ERYTHEMATOSUS: CURRENT EVIDENCE AND CLINICAL PERSPECTIVES - NARRATIVE REVIEW

Filip Chodań, Estera Sośniecka, Olga Klimczak, Adam Miler, Dagmara Laufer, Krystian Domeracki

Background Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease in which persistent activity, organ damage, glucocorticoid dependence, and treatment toxicity remain challenges. Advances in SLE immunopathogenesis have enabled pathway-targeted therapies, but their evidence and clinical readiness varies. Aim To review established and emerging targeted therapies for SLE, including CAR T cell therapy, with emphasis on mechanisms, efficacy, safety, regulatory status, and clinical roles. Materials and …

31.08.2026journal-article

Cancer Medicine

Prognostic Impact of Arterial Phase Hyperenhancement After Proton Beam Therapy for Untreated Solitary Hepatocellular Carcinoma

Hikaru Niitsu, Masashi Mizumoto, Yinuo Li, Masahiko Harada, Takuya Sawada, Masaaki Goto, Taisuke Sumiya, Keiichiro Baba, Takeshi Fujisawa, Masatoshi Nakamura, Toshiki Ishida, Takashi Iizumi, Takashi Saito, Haruko Numajiri, Kei Nakai, Yoshiko Oshiro, Hideyuki Sakurai

ABSTRACT Purpose To evaluate the significance of persistent arterial‐phase hyperenhancement (APHE) on contrast‐enhanced CT/MRI at 6 and 12 months after proton beam therapy (PBT) for hepatocellular carcinoma (HCC). Methods We retrospectively analyzed 108 patients with solitary HCC without vascular invasion who underwent definitive PBT as initial treatment between January 2008 and December 2020. APHE was assessed on contrast‐enhanced CT/MRI at approximately 6 and 12 months. Overall survival (OS), local control (LC), …

31.08.2026journal-article

Small

H 2 S‐Responsive Carbon Dot‐Poly(α‐Lipoic Acid) Nanodrug Delivery Platform for Multimodal Antibacterial Therapy

Hongbo Juan, Xin Wang, Shan Sun, Kelly Kexin Lin, Jingxin Ma, Kefeng Zhou, Mingyan Zhao, Jianping Yang

ABSTRACT The overuse and misuse of antibiotics have accelerated the global antimicrobial resistance crisis, while the therapeutic efficacy of conventional antibiotics remains severely limited by dense biofilm barriers and the complex infectious microenvironment. To address these challenges, we developed an H 2 S‐responsive nanodrug delivery platform (PIP@CDs‐PαLA) based on multifunctional carbon dots (CDs) and poly(α‐lipoic acid) (PαLA), enabling efficient encapsulation of the broad‐spectrum antibiotic piperacillin …

31.08.2026journal-article

Journal of Clinical Microbiology

Evaluation of time to antibiotic therapy after implementation of an updated rapid diagnostic test for gram-negative bacteremia

Rawan Hussein, Leslie Lee, Rajat Nog, Donald Chen, Vishnu Chaturvedi, Nicholas Feola

ABSTRACT Rapid pathogen identification optimizes antibiotic therapy in bacteremia and can be achieved through molecular-based diagnostic tests. This study assesses the clinical impact after the implementation of an updated multiplex PCR panel (BIOFIRE Blood Culture Identification 2, BCID2). This single-center, retrospective, quasi-experimental study compared outcomes in adult patients with gram-negative bloodstream infections (GN-BSIs) pre and post BCID2 implementation. Data were collected from 1 March 2022 to 1 Ma …

31.08.2026journal-article

Physiotherapy Canada

Can Mechanomyography and Heart Rate Be Used to Guide Neuromuscular Electrical Stimulation Delivery in the Non-Responsive Patient? A Cross-Sectional Study in Healthy Adults

Nicholas Markakos, Brittany Wu, Deor Bektashi, Rebecca Campbell, Sabrina Dasouki, Roxana Juan Ding, Sunita Mathur, Jane Batt, Maryam Davoudpour, Vlad Porcila, Alireza Sadeghian, Adriana Ieraci, Sharon Gabison

Abstract Purpose: Neuromuscular electrical stimulation (NMES) may be used to prevent ICU-acquired weakness. Heart rate variability (HRV), mechanomyography (MMG), and pain objectively assess patient experience and muscle response during NMES, which may facilitate its delivery in non-responsive patients. This study investigated the associations between the secondary outcomes of MMG and HRV with the primary outcomes, quality of contraction (QoC), and pain during NMES. Method: Using a cross-sectional design, an NMES pr …

31.08.2026journal-article

Physiotherapy Canada

Return to Sport Guidelines Following Total Knee Arthroplasty: A Scoping Review

Casey Goheen, Travis Goettl, Julien Trapeau, Pulak Parikh, Jennifer Van Bussel, Heather Gillis, Laura Churchill

Abstract Purpose: Our scoping review aimed to explore available evidence on health care providers’ recommendations for return to sport (RTS) after total knee arthroplasty (TKA), particularly in the context of increasing demand among younger patients to restore function, enhance quality of life, and resume sports participation. Method: We searched MEDLINE, CINAHL, Embase, Scopus, and SPORTDiscus for diverse study designs, published between January 1, 1990, and March 30, 2023, that focused on health care provider rec …

31.08.2026journal-article

Annals of Rehabilitation Medicine

Predictors of Paid Employment Status Among Individuals With Spinal Cord Injury in South Korea: An Exploratory Study Using Random Forest Analysis

Kyungah Song, Jincheol Lim, Onyoo Kim

Objective: To explore factors affecting the paid employment of individuals with spinal cord injury (SCI) in South Korea.Methods: Data collected from previously and currently community-dwelling adults with SCI (n=538) who responded to the 125-item self-reported International Spinal Cord Injury Survey questionnaire were analyzed using random forest and decision tree modeling.Results: In total, 75.1% responders were male, 53.9% were unmarried, 90.1% lived with family, and 84.8% received daily living assistance; the mo …

31.08.2026journal-article

BMC Medical Education

Self-reported AI literacy and AI anxiety as correlates of AI attitudes among speech-language therapy students in Türkiye: a cross-sectional study

Şaziye Seçkin Yılmaz, Namık Yücel Birol

Abstract Background Self-reported artificial intelligence (AI) literacy and AI anxiety may be associated with how future speech-language therapists evaluate AI, but evidence specific to this population is limited. Methods This cross-sectional survey examined the independent associations of the observed self-reported AI-literacy composite and AI anxiety with positive and negative attitudes toward AI among 313 fourth-year undergraduate speech-language therapy students from 24 departments in Türkiye. The two dimension …

31.08.2026journal-article

Acute and Critical Care

Korean clinical practice guidelines for rehabilitation in critically ill patients and post-intensive care syndrome

Chi Ryang Chung, Hye Ju Yeo, Eunjeong Choi, Jong Geol Do, Yoonju Na, Jiyeon Kang, Jeong-Yi Kwon, Hyun Jung Kim, Jinyoung Park, Hak-Jae Lee, Myung Hun Jang, Seung-Tak Kang, Kyung Hyup Koo, Young Seok Kim, Won Kim, Tae-Yoon Kim, Jiyoun Park, Jaewon Beom, Kyung Cheon Seo, Hyun-woo Sun, Woochul Son, Myung-Jun Shin, So Young Ahn, Song I Lee, Min-Hyung Rhee, Yu Hui Won, Myungeun Yoo, Yu Jin Im, Sun Ju Chang, Ye Rim Chang, Mi-Kyeong Jeon, Jin Hee Jung, Yumi Ha, Sung Eun Hyun, Suk-Kyung Hong, Gee Young Suh

Background: Survivors of critical illness commonly experience persistent physical, cognitive, and psychological impairments, collectively known as post–intensive care syndrome. Although intensive care unit (ICU) rehabilitation is now recognized as an important part of recovery after critical illness, rehabilitation practices remain inconsistent, and clinical practice guidelines adapted to the Korean healthcare context have not been available.Methods: These clinical practice guidelines were developed de novo by a mu …

31.08.2026journal-article

Canadian Pharmacists Journal / Revue des Pharmaciens du Canada

Personalizing an offer of pharmaceutical care services according to the expectations of youth and stakeholders in a youth rehabilitation centre: The POSER Study

Oumaïma Mahriche, Sandrine Lamy, Ammy Meunier, Tasfia Rahman, Josée Duchesneau, Rachel Rouleau

Abstract Background: Polypharmacy in pediatrics is a growing concern among youth living in residential care centres, where medication use is higher than in the general population. Despite this issue, pharmacists are not currently part of multidisciplinary teams. The POSER study aimed to explore the expectations regarding pharmaceutical care among youth and staff at the centre. Methods: A mixed-methods study was conducted at the Val-du-Lac Youth Rehabilitation Centre (YRC) from June 10 to September 20, 2025. The qua …