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23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Frontiers in Medicine

Fulminant group A streptococcal necrotizing fasciitis presenting as severe calf pain after pharyngitis in an adolescent: a case report

Lisa Roncoroni, Jan Kühle, Lampros Kousoulas, Katharina Müller-Peltzer, Dawid L. Staudacher

Background Invasive Group A Streptococcus (GAS) infection can rapidly progress to life-threatening conditions, including necrotizing fasciitis (NF) and streptococcal toxic shock syndrome (STSS). While typically associated with cutaneous breaches or underlying comorbidities, hematogenous seeding following primary pharyngeal infection is a rare but documented phenomenon. Early diagnosis is often complicated by subtle skin changes and the rarity of the disease. Case A previously healthy 17-year-old female presented wi …

03.09.2026journal-article

Wilderness & Environmental Medicine

Effects of Metal Climbing Gear and Lightning Safety Position During Simulated Lightning

Mathias Maurer, Wolfgang Lederer, Benjamin Treichl, Markus Isser, Sandra Bauchinger, Stephan Pack

Introduction When trapped in a climbing route during a thunderstorm, it is generally recommended that climbers should maintain a maximum distance from rock formations and water accumulations. It is common practice for climbers to untie themselves from the rope and deposit metal equipment a few meters away. Methods In an experimental study, the formation of upward leaders from metal gear attached to a climbing harness and the number of lightning strikes to rope, metal gear, and subject were evaluated. A lightning im …

03.09.2026journal-article

BMC Microbiology

First identification and characterization of a plasmid co-harbouring poxtA and cfr in a clinical linezolid-resistant Staphylococcus aureus isolate

Kang Xu, Kaixin Zhou, Linlin Xu, Qing Chen, Lianyan Xie, Feifei Gu, Aikuang Ma, Shuzhen Xiao, Jingyong Sun, Dongan Zhu

Abstract Background Linezolid remains an important treatment option for serious infections caused by Gram-positive pathogens; however, acquired oxazolidinone resistance genes carried by mobile genetic elements are an increasing clinical concern. In Staphylococcus aureus , cfr and poxtA have previously been reported together in the chromosomal mosaic transposon Tn 6349 , whereas complete plasmid-borne structures co-harbouring these genes remain poorly defined. Methods Isolate D2958 was identified by matrix-assisted …

03.09.2026journal-article

Microbial Drug Resistance

Using an Online Registry of Carbapenemase-Producing Gram-Negative Organisms to Report the Clinical Profile, Outcomes, and Phenotypic and Genotypic Resistances in Two Tertiary Level Hospitals in the Philippines (ORiGiN Study)

Cybele Lara R. Abad, Adrian Ronald A. Espino, Veil Maria T. Castro, Andrei Dominique Montero, Mark B. Carascal, Shanaia Esthelle Joy Daguit, Eariel Francisco, Lawrence S. Macalalad, Kim L. Cochon, Danice Faith Alombro, Benjo P. Ato, Jayson Lumasag, Ralph Bryan B. Hernandez, Anna Flor G. Malundo, Christel V. Gutierrez, Justin Allister Ong, Heather Gutierrez, Karl Abalajon, Marc Agnew M. Cajucom

Background: This study describes the clinical profiles, phenotypic and genotypic resistance mechanisms, and outcomes of patients with carbapenem-resistant infections (CRIs) using a registry. Methods: Hospitalized adults with CRIs in two tertiary institutions were included in this prospective study from January 1, 2023, to December 31, 2025. Results: A total of 411 patients were included. Half were male (207/411, 50.4%), with median age 59 (range 19–98) years. Hypertension (251, 65.5%), diabetes mellitus (150, 39.2% …

03.09.2026journal-article

Current Issues in Sport Science (CISS)

Digital Solutions in Exercise Therapy for Diabetes & Obesity: Using Smart Technology to Get People Moving

Othmar Moser

Physical activity and structured exercise are essential components of the management of diabetes and obesity (Moser et al., 2020)(Davies et al., 2022). Nevertheless, many people do not achieve recommended activity levels, and the translation of exercise recommendations into everyday life remains challenging. Digital solutions may help to overcome this gap by providing personalised guidance, continuous feedback and scalable support beyond traditional clinical settings (Moser et al., 2025). This keynote will explore …

03.09.2026journal-article

Journal of Intensive Care Medicine

Incidence and Risk Factors for Invasive Mechanical Ventilation Dependency in Japan: A Nationwide Retrospective Cohort Study

Hiroyuki Ohbe, Monique Daniels, Daisuke Kudo, Hiroki Matsui, Stef Groenewoud, Werner Brouwer, Hideo Yasunaga

Objectives To describe the incidence and risk factors for becoming dependent on invasive mechanical ventilation (IMV) in Japan. Design Retrospective cohort study using a nationwide inpatient database from April 1, 2014, to March 31, 2020. Setting More than 1500 acute care hospitals participating in the Diagnosis Procedure Combination Study Group Database, covering approximately 50% of all hospitalizations in acute care hospitals in Japan. Patients Adults (≥18 years), in whom IMV was initiated during hospitalization …

03.09.2026journal-article

European Journal of General Dentistry

Conservative Esthetic Approach for Crown Fracture with Pulp Exposure in a Young Male Patient: A Case Report with Mini-review

Naif N. Abogazalah

Abstract Traumatic dental injuries may hurt the social and psychological well-being of a young patient. Maxillary anterior teeth are the most affected teeth. In permanent dentition, the most common trauma involves clinical crown fractures, with or without pulp exposure. This article describes a case report of a 12-year-old male patient who exhibited dental trauma, which resulted in a complicated crown fracture with pulp exposure of tooth #11 (maxillary right central incisor). A partial pulpotomy was performed to pr …

03.09.2026journal-article

Journal of Imaging Informatics in Medicine

A Clinically Grounded Review of Medical Image Classification: Quantitative Insights into CNNs, Vision Transformers, and Hybrid CNN-ViT Models

Hamza Hussaini, Shahana Bano, Eyad Elyan, Carlos Francisco Moreno-Garcia

Abstract Medical image classification has advanced substantially with convolutional neural networks (CNNs), Vision Transformers (ViTs), and hybrid CNN–ViT architectures, yet clinical translation remains limited by dataset dependency, inconsistent evaluation practices, and insufficient external validation. This review provides a clinically grounded comparative synthesis of these model families across diverse medical imaging modalities. A structured literature review was conducted across PubMed, IEEE Xplore, Scopus, …

03.09.2026journal-article

Transplantologiya. The Russian Journal of Transplantation

A rare complication in a patient undergoing continuous ambulatory peritoneal dialysis

A. G. Yankovoy, V. A. Stepanov

Introduction. Continuous ambulatory peritoneal dialysis (PD) is one of the methods of treating patients in the structure of renal replacement therapy (RRT). The most common complications directly related to the peritoneal catheter usually occur during the first weeks and range from catheter dysfunction to dialysis peritonitis. Delayed intestinal perforation with a peritoneal catheter upon termination of peritoneal dialysis (PD) is extremely rare. Objective. The article describes a rare clinical case and successful …

03.09.2026journal-article

Journal of Clinical Medicine

Structural Deficit-Guided Reconstruction of an Extended Lower Eyelid–Bicanthal Defect

Zheng-Cai Wang, Zi-Chun Gu, Ying Hu, Jia-Qin Cai, Hua Li

Background/Objectives: Extended lower eyelid defects involving both lamellae and canthal supports require restoration of lining, support, vascularized coverage, and horizontal stability. We describe a two-stage reconstruction guided by structural deficits and available autologous tissues. Methods: A 63-year-old man underwent staged excision with frozen-section margin control for conventional-type basal cell carcinoma involving almost the entire right lower eyelid. A lengthened septal chondromucosal graft restored p …

03.09.2026journal-article

Toxins

Toxic Plants Potentially Impacting the Health Status of Livestock in St. Kitts—A Surveillance Study

Andras-Laszlo Nagy, Francesca Caloni, Regina Tose Kemper, Sofia Gonzalez Lleras, Heather Beigh, Christian DeJean, Maurice Matthew, Georgios Paraschou

Tropical regions are characterized by exceptional biodiversity, including extremely diverse flora. Many plants produce chemical compounds that function as defense mechanisms, some of which are toxic to mammals, including livestock species. However, documentation of toxic plants in the Caribbean region remains limited. The present study aimed to identify toxic and potentially toxic plant species affecting livestock on the island of Saint Christopher (St. Kitts) through surveys of a representative number of farms acr …

03.09.2026journal-article

Student's Journal of Health Research Africa

<b>Influence of at-risk gambling on the mental well-being of the youth in Nakawa Division, Kampala District, Uganda. A cross-sectional study.</b>

Albert Louis Elwa, Clesistom Ahimbisibwe, Frank Kiyingi, Robert Oluka

Background: The football pools are still around today and are, in fact, the source of inspiration for fixed odds on gambling. To assess the influence of at-risk gambling on the mental well-being of the youth in Nakawa Division, Kampala District, Uganda. Methodology: The study employed a cross-sectional survey research design. Quantitative data were analysed using a computerised data analysis program known as the Statistical Package for Social Sciences (SPSS) version 25. Results: There was a significant but negative …

03.09.2026journal-article

Chinese Medicine and Culture

China's Most Beautiful Imperial Illustration-Colored Manuscript :A History of the Overseas Dissemination and Global Circulation of Ben Cao Pin Hui Jing Yao (《本草品汇精要》Collected Essentials of Species of Materia Medica)

Hui Cao, Qing Wu

Abstract: Ben Cao Pin Hui Jing Yao (《本草品汇精要》 Collected Essentials of Species of Materia Medica ) is an official materia medica text that was compiled and revised by Tai Yi Yuan (太医院the Imperial Academy of Medicine), completed in the eighteenth year of the Hongzhi era (1505 AD) under Emperor Xiaozong (孝宗) in Ming Dynasty. As the last pharmacopoeia in ancient China, it was even earlier than the Nuremberg Pharmacopoeia issued by the European Nuremberg Senate in 1546 AD. However, the book was not published, because Emp …

03.09.2026journal-article

The Prison Journal

Pathways to Homicide: Trauma, Mental Health and Reintegration Challenges Among Incarcerated Women in India

Pooja Tyagi, Meenu Sharma, Rajni Sharma, Mehek Arora, Raj Ratan

This qualitative study examines the trauma histories, mental health profiles, socioeconomic circumstances and reintegration concerns of 50 women incarcerated for homicide in four North Indian prisons. Applying a feminist pathways framework, semistructured interviews were analysed using reflexive thematic analysis. Four themes emerged: cumulative victimisation, untreated psychological distress, structural entrapment and reintegration precarity, reflecting widespread domestic violence, psychological distress, poverty …

03.09.2026journal-article

Japan Journal of Nursing Science

Nurses' Visual Attention During Initial Observation of Patients With Suspected Pneumonia: An Observational Pupillometry Study

Shoya Kamijo, Shinji Matsutani, Eijun Nakayama, Naoya Ohtani

ABSTRACT Aim Observation requires selective attention to visual information acquired through gaze. Measuring pupil diameter, an index of attention, we examined skilled and novice nurses during the initial assessment of a patient urgently admitted with suspected community‐acquired pneumonia. Methods This observational study was conducted in a simulated environment. Participants comprised skilled nurses with advanced practice training and novice nurses. During a 120‐s initial assessment of a mock patient with suspect …

03.09.2026journal-article

BMC Medicine

Diagnostic accuracy of attended versus unattended automated blood pressure measurements compared to ambulatory blood pressure monitoring conducted by community health workers in rural sub-Saharan Africa

Ruth K. Lucinde, Modou Jobe, Alexander D. Perkins, Juliet O. Awori, Boniface Karia, Lamin Jobarteh, Robinson Oyando, Catherine Kalu, Sampa Sanneh, Clement Mwagwabi, Elminah Saru, Aurelia Brazeal, Samson Kinyanjui, Robert N. Peck, David A. Leon, Andrew M. Prentice, Benjamin Tsofa, Anoop S.V. Shah, Pablo Perel, Anthony O. Etyang, on behalf of the IHCoR-Africa Collaborators

Abstract Background Community Health Workers (CHWs) are increasingly being involved in screening for hypertension in rural sub-Saharan Africa. However the diagnostic accuracy of CHW-led attended (CHW present during procedure) and unattended (CHW absent) automated blood pressure (BP) in home settings has not been compared. Methods We conducted a cross-sectional, population-based diagnostic accuracy study in two health and demographic surveillance systems in Kenya and The Gambia. A random age-stratified sample of ind …

03.09.2026journal-article

Herz

Predicting LDL-cholesterol reduction variability on statin–ezetimibe therapy: insights from “Jena auf Ziel”

Umidakhon Makhmudova, Dieter Lütjohann, Franz Haertel, Anja Kerksiek, Robert Römer, Pellumb Haxhikadrija, Aurel Maloku, Beasat Samadifar, Sylvia Otto, P. Christian Schulze, Oliver Weingärtner

Abstract Background and aims Low-density lipoprotein cholesterol (LDL-C) is a causal risk factor for atherosclerotic cardiovascular disease (ASCVD). ESC/EAS guidelines recommend reducing LDL-C < 1.4 mmol/L and > 50% from baseline in patients with myocardial infarction. “Jena auf Ziel” (JaZ) is a prospective cohort study in which early combination therapy with atorvastatin 80 mg and ezetimibe 10 mg was initiated on admission in patients with ST-elevation myocardial infarction (STEMI) to reduce LDL‑C levels early and …

03.09.2026journal-article

Healthcare

From Intelligent Operating Room to Smart ICU: Digital Continuity, AI-Supported Decision-Making and CRRT as a Model of Pharmacokinetic Personalization in Critical Care

Leonard Azamfirei, Mirela Cecilia Oiaga, Mihai Claudiu Pui

Critically ill patients frequently move between the intensive care unit (ICU) and the operating room while remaining dependent on ventilatory, hemodynamic, antimicrobial, sedative, analgesic, and renal support. Although extensive perioperative data are generated, clinically relevant information may remain fragmented across devices and electronic systems. This narrative review synthesizes the literature published primarily between 2016 and 2026 on perioperative digital continuity, structured ICU–operating room hando …

03.09.2026journal-article

Journal of Pharmaceutical Research and Integrated Medical Sciences

Multimodal AI and Machine Learning for Predictive Risk Stratification, Early Detection, And Clinical Management of Pica: Integrating Etiological and Pathophysiological Biomarkers

Yash Srivastav, Stuti Verma, Kamini Prajapati, Sandeep Prakash, Rajeev Kumar, Anubha Dhuriya, Anup Kumar Sirbaiya, Shivani Singh

Pica is a clinically significant and often overlooked feeding and eating disorder in which individuals have a persistent urge to eat or chew non-nutritious or non-food items and is linked to nutritional, hematological, behavioral, and environmental issues. Human studies have regularly found links between pica and iron deficiency and anemia, as well as between changes in hematological parameters, decreased ferritin, and decreased zinc concentrations; toxic-element exposure may also be a part of certain behaviors (li …

03.09.2026journal-article

Frontiers in Cellular and Infection Microbiology

Absolute quantification by mouthwash testing screens severe periodontitis and tracks species-specific microbial response to periodontal therapy

Je-Hyun Eom, Mu-Yeol Cho, Ji-Won Kim, Yunwoo Kim, Jeehyun No, Jiyoung Hwang, Seokwon Kim, Dahye Lee, Hanseung Baek, Bae-Kyung Kim, Young-Youn Kim, Soo-Bok Her, Dong-Yub Ko, Inseong Hwang, Hye-Sung Kim

Background Non-invasive molecular tools that can both screen for severe periodontitis and quantify treatment-associated pathogen changes remain an unmet need. We evaluated a non-invasive multiplex quantitative polymerase chain reaction (qPCR) mouthwash panel providing absolute colony-forming-unit (CFU) quantification of five periodontal pathogens ( Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, Prevotella intermedia, Fusobacterium nucleatum ), and asked whether a single test can both screen fo …

03.09.2026journal-article

Frontiers in Psychiatry

Anxiety- and depression-related somatic symptoms and atlantoaxial disorders: potential mechanistic links and clinical implications

Shuxian Yang, Qianru Li, Wanying Shi, Xiaoyun Liu

Background Anxiety and depressive disorders often include pain, dizziness, headache, fatigue, nausea, and sleep disturbance. These symptoms may also occur in atlantoaxial disorders, but overlap does not establish a shared cause. Objective To examine whether clinical or mechanistic evidence supports an association between objectively defined atlantoaxial disorders and somatic symptom burden in people with anxiety or depression, while distinguishing direct evidence from inferences based on general neck-pain research. …

03.09.2026journal-article

Frontiers in Public Health

Mental disorders in the Black population: a scoping review

Rondinelli Salvador Silva, Yasmim Souza Rodrigues, Eduardo Sodré de Souza, Bruno Pereira da Silva, Luanda Ferreira Dias de Souza, Igor Hagedorn Reis, Ana Paula de Morais e Oliveira, Deivison Faustino Mendes, Patricia Lima Ferreira Santa Rosa

Introduction Mental disorders, psychiatric diagnosis, DSM/ICD classification, and mental health care represent major sources of global morbidity shaped by biological processes, social stressors, structural racism, inequities, and access barriers. In the Black population, racism, discrimination, social exclusion, and institutional bias may affect recognition, diagnosis, treatment, prognosis, and psychiatric outcomes. This scoping review aimed to map and summarize the available evidence on mental disorders in the Bla …

03.09.2026journal-article

Frontiers in Medicine

Development and validation of a nomogram prediction model for perioperative delirium in older patients with osteoporotic fractures based on LASSO regression and multiple parameters

Ni Hua, Hongmei Yuan, Yanhong Wei, Zhenqi Wei, Yanping Feng, Yong Liu, Tongguang Xu, Suliang Zhao, Li Zhang, Xiaohong He

Background Perioperative delirium (POD) is a severe postoperative complication in older patients with osteoporotic fractures. This study aimed to establish a nomogram prediction model incorporating multisystem stress, inflammation and frailty-related biomarkers for risk prediction. Methods This retrospective cohort study included 176 older patients (≥65 years) with osteoporotic fractures. Potential predictors, including the rate-pressure product (RPP), systemic inflammation response index (SIRI) and prognostic nutr …