EUVIMEDEuropean Health Evidence
Uhr 7/7Sources Journal Tree
Easy Demo

EUVIMED Themenbrowser · Therapie & Reha · Seite 29

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

Themen erkunden

Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
31.08.2026journal-article

Frontiers in Pediatrics

Association of depressive symptoms with sweat chloride variability and medication possession ratio during long-term Elexacaftor/Tezacaftor/Ivacaftor therapy in adolescents and young adults with cystic fibrosis

Michael Lorenz, Mariya Pavlova, Katja Erler, Anika Nader, Anne Moeser

Introduction Elexacaftor/tezacaftor/ivacaftor (ETI) sustainably improves lung function (FEV₁), quality of life and sweat chloride (SC) levels in people with cystic fibrosis (pwCF). Psychological comorbidities may impair treatment adherence. This study assessed ETI adherence using SC and medication possession ratio (MPR) and evaluated the impact of depressive symptoms. Methods In this retrospective observational study, 34 pwCF aged 12–21 years (median 17.3) initiating ETI between 2020 and 2022 were included. SC and …

31.08.2026journal-article

Journal of Veterinary Emergency and Critical Care

Use of Intralipid Therapy and Therapeutic Plasma Exchange in the Management of Cholecalciferol Rodenticide Exposure in a Dog: A Case Report

Tanvi A. Kamat, Kara D. Altman, Emma Donnelly, Neus Elias Santo‐Domingo

ABSTRACT Objective To describe the presentation and outcome of a case of suspected cholecalciferol rodenticide intoxication managed with both intralipid emulsion (ILE) and therapeutic plasma exchange (TPE). Case Summary A 3‐year‐old, neutered female, crossbreed dog presented for acute‐onset vomiting and lethargy after suspected exposure to cholecalciferol rodenticide. Severe hypercalcemia was observed without other identifiable causes found upon investigation. Standard therapy for hypercalcemia was initiated, but r …

31.08.2026journal-article

TAMADDUN NURI JURNALI

ЦИФРОВАЯ СРЕДА ДЛЯ СВОБОДНОЙ РЕЧИ: АВТОРСКАЯ ПЛАТФОРМА “ГОВОРИ-КА” В ОБУЧЕНИИ РУССКОМУ ЯЗЫКУ

Гулчехра Жабборова

The article presents the author’s digital “Speak Up” platform designed to develop fluent, confident, and accurate Russian speech. The platform is based on the principle of moving from knowledge of language rules to independent speech production. The article describes the author’s model for organizing a digital speech environment that integrates lexical, grammatical, and communicative practice through the sequence “understand → try → speak → correct → engage in communication”.

31.08.2026journal-article

Journal of Cognitive Psychotherapy

Development and Pilot Testing of Internet-Delivered Cognitive Behavioral Therapy for Anxiety and Obsessive-Compulsive Disorders in Autistic Adolescents

Jessica Szu-Chi Cheng, Jolie B. Held, Callie G. Murphy, Ogechi “Cynthia” Onyeka, Andrew G. Guzick, David B. Riddle, Leandra N. Berry, Robin P. Goin-Kochel, Marianna C. Messerli, Jeffrey A. Carter, Mariana Vazquez, Erika S. Trent, Peter J. Boedeker, Troy Quast, Eric A. Storch

Anxiety disorders are prevalent in autistic adolescents, yet barriers to treatment access exist. The current article describes (a) the development of an internet-delivered, therapist-assisted cognitive behavioral therapy protocol adapted for autistic adolescents with co-occurring anxiety and/or obsessive-compulsive disorder and (b) preliminary feasibility, acceptability, and effectiveness data. Ten autistic adolescents between the ages of 11 and 17 were enrolled. Based on qualitative feedback and quantitative data …

31.08.2026journal-article

Journal of Inherited Metabolic Disease

Phase 3 Randomized Trial Results of DTX401 AAV Gene Therapy for the Treatment of GSDIa

John J. Mitchell, Jose E. Abdenur, Foekje de Boer, Monica Boyer, Margo Sheck Breilyn, María‐Luz Couce, Diva D. De Leon, Terry G. Derks, Areeg El‐Gharbawy, Andrea B. Haijer‐Schreuder, Karen Loechner, Nicola Longo, Allan M. Lund, Miguel Angel Martinez Olmos, Shawn E. McCandless, Bibiana Mello de Oliveira, Malaya Mount, Nicole Muschol, Kristina Pytlak, Kadakkal Radhakrishnan, Rebecca Riba‐Wolman, David F. Rodriguez‐Buritica, Alessandro La Rosa, Alessandro Rossi, Heather Saavedra, René Santer, Brian Shayota, G. Peter A. Smit, Carolina F. Moura De Souza, Melanie M. van der Klauw, David A. Weinstein, Joseph I. Wolfsdorf, Anne Blake, Andrew A. Grimm, Deepali Mitragotri, Syeda Rahman, Diane M. Turner‐Bowker, Richard Collis

ABSTRACT Glycogen storage disease type Ia (GSDIa) is a rare, life‐threatening inherited carbohydrate metabolism disorder caused by biallelic pathogenic G6PC gene variants resulting in deficiency of glucose‐6‐phosphatase. DTX401 is an investigational AAV8 vector containing the human G6PC gene. DTX401‐CL301 is a pivotal, phase 3, double‐blind, randomized, placebo‐controlled trial of DTX401 in patients ≥ 8 years with GSDIa. The primary endpoint was percent change from Baseline to Week 48 in daily cornstarch intake for …

31.08.2026journal-article

Medicina

Prognostic Value of the Modified Glasgow Prognostic Score in Patients with Metastatic Renal Cell Carcinoma Receiving Nivolumab as Second-Line Therapy: A Multicentre Retrospective Cohort Study

Sedat Biter, Ertuğrul Bayram, Tolga Köşeci, Mehmet Cihan İçli, Ahmet Melih Arslan, Faruk Recep Özalp, Nadiye Sever, Ahmet Ünsal, Nargiz Majidova Altuntaş, Mustafa Seyyar, Gülhan Dinç, Mahmut Büyükşimşek, Mehmet Türker, Şendağ Yaslıkaya, Mehmet Mutlu Kıdı, Yasemin Aydınalp Camadan, Umut Kefeli, Mehmet Uzun, Hasan Çağrı Yıldırım, Hüseyin Salih Semiz, Mustafa Erman, İsmail Oğuz Kara

Background and Objectives: The modified Glasgow Prognostic Score (mGPS)—a composite of serum C-reactive protein (CRP) and albumin—simultaneously reflects systemic inflammatory activity and nutritional reserve. Its specific prognostic role in patients with metastatic renal cell carcinoma (mRCC) treated with nivolumab in the second-line setting has not previously been examined in a large multicentre cohort. The aims of this study are to determine whether baseline mGPS independently predicts overall survival (OS) and …

31.08.2026journal-article

Natural and Life Sciences Communications

Occupational Health Risks from Pesticide Exposure: Evidence from Thai Farmers

Pronrumpa Kanjanasingh, Thittaya Ngamsang, Preechaya Tajai

Several pesticides are widely used in agriculture, yet many farmers lack adequate knowledge and protective practices, increasing risk of exposure and related health effects. This study aimed to screen health risks and analyze the factors affecting pesticide exposure among farmers in Chachoengsao Province, Thailand. Cross-sectional study was performed. Data were collected from 177 farmers who volunteered to participate. For pesticide exposure, 81.92% of farmers currently use pesticides, 57.25% sprayed pesticides the …

31.08.2026journal-article

Nano Letters

An Oral Biomimetic Hydrogel for Colon-Localized and Tumor-Targeted Sonodynamic Therapy of Colorectal Cancer

Zeyang Tian, Jie Yang, Ya-Xuan Zhu, Han Lin, Jianlin Shi

Abstract Oral drug delivery systems show great promise for colorectal cancer (CRC) therapy but are limited by poor gastrointestinal stability, insufficient colon localization, and low tumor targeting. Here, we report an oral biomimetic hydrogel platform, SAM/Au-TiO2@Gel, for colon-localized and tumor-targeted sonodynamic therapy of CRC. Au deposition enhances the sonodynamic reactive oxygen species (ROS) generation capability of TiO2, while Staphylococcus aureus membrane (SAM) coating improves tumor targeting and u …

31.08.2026journal-article

Journal of Basic and Clinical Physiology and Pharmacology

Emulgel preparation from ethanol extract of red ginger rich in 6-shogaol as therapy for diabetic neuropathy pain: targeting TRPV-1 down-style

Fifteen Aprila Fajrin, Diana Holidah, Fransiska Maria Christianty, Ika Puspita Dewi, Arief Nurrochmad, Heni Nurhidayah

Abstract Objectives Painful diabetic neuropathy is a long-term complication of diabetes mellitus. However, the limitations of topical drug therapies have led to the development of plant-based treatments, such as red ginger. This study aimed to investigate the effectiveness of a red ginger extract emulgel (RGEE) for PDN. Methods Mice were divided into seven groups: normal, PDN, positive control using capsaicin cream, and four treatment RGEE at 1 %, 2%, 3%, and 4 %. Mice were induced diabetic using streptozotocin 120 …

31.08.2026journal-article

Jurnal Psikologi Sains dan Profesi

Mandala Art Therapy untuk Menurunkan Kecemasan pada Remaja SMPN X Kabupaten Bantul

Fadhillah Zahra Widafina, Innes Yonanda

Kecemasan merupakan permasalahan psikologis yang umum dialami remaja pada masa tran sisi perkembangan, hal ini dapat mengganggu fungsi akademik maupun sosial apabila tidak ditangani secara adaptif. Penelitian ini bertujuan mengkaji efektivitas intervensi kelompok berbasis mandala art therapy dalam menurunkan kecemasan pada remaja SMP, dengan membandingkan skor kecemasan subjek penelitian sebelum dan sesudah rangkaian intervensi. Subjek dalam penelitian ini adalah enam siswa kelas VII SMP X di Kabupaten Bantul yang …

31.08.2026journal-article

Frontiers in Pediatrics

Virtual reality for rehabilitation and engagement in pediatric intensive care: a systematic review of feasibility, safety and outcomes

Insu Choi, Hwa Jin Cho, Kibum Kim, Sunyong Yoo, Min-Keun Song

Children admitted to pediatric intensive care units (PICUs) are at risk of acquired weakness, delirium, and long-term functional and neurocognitive morbidity. Although early rehabilitation is recommended to mitigate these adverse outcomes, its delivery remains challenging. Virtual reality (VR) has been proposed as a means of enhancing engagement in rehabilitation in this setting. This systematic review evaluated the feasibility, safety, and outcomes of VR delivered to children during routine pediatric intensive car …

31.08.2026journal-article

Archives of The Medicine and Case Reports

Green-Laser-Flanged Intrascleral Fixation of a Secondary Intraocular Lens in Aphakia with Reduced Endothelial Reserve: Rapid Visual Rehabilitation, a +1.00 Dioptre Prediction Error, and a Minimum Reporting Data Set

Ade John Nursalim, Yovita

Background: Aphakia without capsular support is decided largely by the state of the corneal endothelium. Objective: To present the result with a structured audit of the record and a numbered minimum data set for reporting laser-flanged intrascleral fixation. Methods: A 60-year-old man was referred twelve months after left phacoemulsification complicated by posterior capsule rupture, with no lens implanted. Best-corrected acuity with a +10.00 D aphakic spectacle was 20/200 (1.00 logMAR), uncorrected acuity was count …

31.08.2026journal-article

Annals of Rehabilitation Medicine

Comparing the Values of Tissue Fluid Accumulation Using Tissue Dielectric Constant and Bioimpedance Analysis in Healthy Volunteers

Min Kyung Park, Chang Hyun Lee, Su-Hong Choi, In Joo Kong, Jin A Yoon

Objective: To quantitatively assess short-term, intervention-associated changes in tissue water distribution using tissue dielectric constant (TDC) and bioimpedance analysis (BIA) in healthy volunteers, and to explore correlations between the two modalities.Methods: Thirty-one healthy participants underwent a lymphedema-related intervention on their dominant arm, which included pumping and clearing of the terminus, manual lymphatic drainage, and low-level laser therapy. TDC and BIA were measured before and after th …

31.08.2026journal-article

Trials

Efficacy and cost-effectiveness of Internet-delivered cognitive-behavior therapy for children and adolescents with body dysmorphic disorder: study protocol for a randomized controlled trial

Lorena Fernández de la Cruz, Anita Birovecz, Per Andrén, Karin Melin, Kristina Aspvall, Matti Cervin, Erik Andersson, Maria Silverberg-Mörse, Martina Gumpert, Frida Wickberg, Matteo Bottai, Eva Serlachius, Daniel Rautio, David Mataix-Cols

Abstract Background Body dysmorphic disorder (BDD) is a prevalent and impairing mental disorder that typically onsets in adolescence. Cognitive-behavior therapy (CBT) may be effective for adolescent BDD, although the supporting evidence is currently limited. CBT for BDD is a highly specialized treatment, creating a considerable gap in access to care for young people. Therapist-guided Internet-delivered CBT (ICBT) may help bridge this gap. The primary aim of this study is to determine the efficacy of a therapist-gui …

31.08.2026journal-article

Sustainability

A Systematic Review of Integrative Approaches for the Multidimensional Analysis of Sustainable Soil Rehabilitation

João Teixeira e Costa, Maria Cristina Vila, Maria Manuela Carvalho

Soil contamination represents a pervasive and multifaceted threat to environmental integrity, public health, and sustainable land use. In response to this challenge, this systematic review synthesizes recent advancements in sustainable soil remediation techniques, with an emphasis on bioremediation, nature-based solutions (NBSs), innovative physicochemical methods, and multidimensional assessment frameworks. Utilizing the adapted PRISMA methodology, 3222 peer-reviewed articles published between 2015 and 2025 were i …

31.08.2026journal-article

The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy

Beta-1,3/1,6-D-Glucan Extracted from Ganoderma lucidum as Adjunct Therapy in Ulcerative Colitis: A Case Series

Saskia Aziza Nursyirwan, Marcellus Simadibrata, Rabbinu Rangga Pribadi, Virly Nanda Muzelina, Hasan Maulahela, Amanda Pitarini Utari, Enrik John Aguila, Ardhia Fefrine Indarta

The management of ulcerative colitis is primarily focused on the prevention of complications, remission sustenance, and enhancement of overall quality of life. However, long-term use of various pharmacological therapies can be associated with several side effects, including myelosuppression, hepatitis, lupus-like syndrome, and an increased risk of malignancy. These limitations have led to the search for safer therapeutic options, including bioactive compounds such as Beta-1,3/1,6-D-Glucan with immunomodulatory prop …

31.08.2026journal-article

Clinical Case Reports

Rhabdomyolysis Associated With Heated Massage Therapy in a Patient Without Major Trauma: A Case Report

Ashani Ratnayake, Sayomi Warnakula, Yasitha Handapangoda, Udara Rathnayake, Lasanthika Athapaththu, Sanduni Rupasinghe

ABSTRACT A 29‐year‐old professional dancer developed rhabdomyolysis after distal radial fracture fixation complicated by laryngospasm, negative pressure pulmonary oedema, suxamethonium use, and ICU admission. Creatine phosphokinase (CPK) peaked at 36,429 U/L with dark urine and hyperkalaemia. Recent prolonged heated massage‐bed use, with minor trauma and suxamethonium, may have contributed. Biopsy confirmed skeletal muscle necrosis.

31.08.2026journal-article

Bioinformation

Prevalence of untreated dental caries requiring endodontic therapy among rural and urban populations in India: A cross-sectional study

Kamil Shahnawaz

Dental caries is a major public health concern. If it is not treated in time, it can result into abscess and tooth loss. Therefore, it is of interest to determine and compare the frequency of unfilled caries that need root canal therapy among rural and urban adults in India. A cross-sectional study was carried out on 452 persons (226 rural, 226 urban). Clinical examination was done according to WHO oral health assessment criteria. Rural populations exhibit a higher burden of advanced dental caries requiring endodon …

31.08.2026journal-article

Psychiatry and Clinical Neurosciences

From public preferences to clinical tasks in anti‐amyloid therapy for Alzheimer's disease

Kyohei Otani

Tajika and colleagues found that, among Japanese respondents willing to consider lecanemab, the median smallest worthwhile difference exceeded the absolute benefit used in their study scenario. This commentary argues that this expectation–efficacy gap should be translated into concrete clinical tasks across the anti‐amyloid care pathway, including expectation assessment, biomarker and eligibility counseling, shared decision‐making, treatment monitoring, support for non‐initiation or discontinuation, and continuing …

31.08.2026journal-article

Journal of Craniofacial Surgery

Thermoformed Aligner Therapy for Presurgical Orthodontic Preparation in a Cleft Lip and Palate Patient With Multiple Sclerosis

Cynthia Dabed, Ignacio Fuentes, Gabriela La Valle

We present a 15-year-old female with a complete right unilateral cleft lip and palate (UCL/P), no prior alveolar bone graft, and multiple sclerosis (MS) requiring periodic MRI monitoring, in whom metallic fixed appliances were contraindicated. A sequence of 18 thermoformed aligners per arch achieved dentoalveolar expansion, alignment, leveling, torque correction, and preparation of the alveolar cleft site over ~10 months, including strategic extraction of a palatal supernumerary tooth 3 months before grafting. MRI …

31.08.2026journal-article

Cerrahpaşa Medical Journal

Local versus Spinal Anesthesia for Endovenous Ablation Therapy: A Comparative Study

Berk Arapi, Çiğdem Tel Üstünışık, Ozan Onur Balkanay, Elif Çiftçi, Nevzat Cem Sayılgan, Serkan Burç Deşer, Deniz Göksedef, Suat Nail Ömeroğlu, Gökhan İpek

Objective: Endovenous thermal ablation techniques such as endovenous laser ablation (EVLA) and radiofrequency ablation (RFA) are widely used in the treatment of chronic venous insufficiency. These procedures can be performed under different anesthesia techniques, most commonly local or spinal anesthesia. However, comparative data regarding their perioperative outcomes remain limited. This study aimed to compare the clinical outcomes of endovenous ablation performed under local anesthesia vs. spinal anesthesia in pa …

31.08.2026journal-article

Bioinformation

Biological susceptibility to root resorption in clear aligner therapy: A mini review

Mariana Lourdes Barrionuevo

External apical root resorption (EARR) persists in clear aligner therapy and reflects individual biological susceptibility more than appliance type. Polymorphisms in inflammatory and vitamin D pathway genes, including IL1B, RANK and VDR, shift individual EARR risk. Gingival crevicular fluid biomarkers, such as interleukin-6, interleukin-8 and matrix metalloproteinase-8, track the active resorptive phase. AI-assisted three-dimensional imaging quantifies apical loss objectively, near 0.6 to 0.8 mm and comparable to f …

31.08.2026journal-article

Journal of Pastoral Care & Counseling: Advancing theory and professional practice through scholarly and reflective publications

Comparing the Art of Midwifery Practice to Spiritual Care: Common Characteristics Emerging from Theoretical Models and Field Work

M-N Bélanger-Lévesque, S Crowther

This article offers an original comparative analysis of spiritual care providers and midwives using two theoretical models, the “art of midwifery practice” and “practiced spirituality”. The analysis draws on interview data from ten New Zealand midwives. Focusing on presence, guardianship, intuition, confidence/courage, and human relationship, the analysis reveals shared yet distinct ways of enacting care, illuminating overlooked dimensions of spiritual care practice, and opening new avenues for interdisciplinary re …

31.08.2026journal-article

International Journal of Advanced Research

ACUTE OCCUPATIONAL HYDROGEN SULFIDE POISONING IN A CONFINED SPACE: REPORT OF TWO CASES

ArmelB ArmelB, El Rhabali G, Benabbdellah I, Belhacene A, Zarouali H, Sebbata O, El Moussaoui R

Hydrogen sulfide (H2S) is a highly toxic gas commonly encountered in sanitation systems and certain industrial settings [1,2]. Acute poisoning occurs mainly in occupational settings and constitutes a medical emergency due to the rapid onset of neurological and respiratory complications, whose severity depends on gas concentration and exposure duration [3,5]. We report two cases of accidental H2S poisoning in confined spaces among sanitation workers. Both patients were admitted to the emergency department with alter …