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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
02.09.2026journal-article

Frontiers in Nutrition

Flavonoids: biological activities, nutritional and immunological aspects, therapeutic potential, food applications, and human health benefits—A comprehensive review

Mohamed T. El-Saadony, Ahmed M. Saad, Mohamed A. Fahmy, Dina Mostafa Mohammed, Dina Khodeer, Esmael M. Alyami, Samar Sami Alkafaas, Mthokozisi Dladla, Soumya Ghosh, Mohammad A. A. Al-Najjar, Synan F. AbuQamar, Khaled A. El-Tarabily

The global burden of infectious and non-communicable diseases presents a critical challenge, highlighting the urgent need for novel, safe, and effective therapies. Bioactive compounds from medicinal plants, especially flavonoids, offer a promising resource for drug discovery due to their diverse and potent pharmacological effects documented in preclinical studies. This comprehensive review summarizes current knowledge of flavonoids, including their classification into 14 main groups and their production via biosynt …

02.09.2026journal-article

Journal of Nervous & Mental Disease

A Comparison of Tardive Dyskinesia With First- and Second-Generation Antipsychotics in Postmarket Surveillance Data

Joyce Hanyue Gu, Mark Samarneh

Introduction: Tardive dyskinesia (TD) is a known adverse drug reaction (ADR) of first-generation and second-generation antipsychotics. While second-generation antipsychotics are believed to pose a lower TD risk, evidence remains mixed. This study compares TD risk between first- and second-generation antipsychotics using postmarket ADR data. Study Type: Observational cross-sectional pharmacovigilance analysis. Methods: We conducted a disproportionality analysis of the FAERS database from 2012 to 2024, calculating th …

02.09.2026journal-article

Smart Materials and Structures

Direct ink writing of flexible strain gauges for IoT-enabled structural health and usage monitoring of aerospace composites

Marilyne Philibert, Yuhang Pan, Ferri M.H Aliabadi, Zahra Sharif Khodaei

Abstract Structural health and usage monitoring of aerospace structures requires scalable, lightweight, and minimally intrusive sensing solutions capable of supporting real-time digital twin frameworks for individual aircraft life management. This work presents the development and characterization of flexible printed strain gauges as a core sensing component of the IoT sensing skin developed within the H2020 AVATAR project, dedicated to developing a digital twin framework for real-time health and usage monitoring o …

02.09.2026journal-article

REVISTA SISTEMÁTICA

ASPECTOS PSICOSSOCIAIS E EDUCACIONAIS DA SAÚDE MENTAL

Betijane Soares de Barros, Bernard Pereira Almeida, Joselito Araújo Silva, Lucilia Maria da Silva Soares Barbosa, Maria de Lourdes Pessoa Alves, Ivaci Bomfim Pinheiro, Ingrid Francinne Accioly Lira, Pauliana Oliveira dos Santos

A saúde mental no ensino superior constitui um desafio complexo e urgente na atualidade. O objetivo deste artigo é analisar os impactos dos aspectos psicossociais e educacionais na saúde mental de estudantes universitários, identificando os principais fatores de risco e de proteção presentes no ambiente acadêmico. A metodologia adotada consiste em uma revisão de literatura, realizada por meio do levantamento e análise de artigos científicos indexados em bases de dados nacionais e internacionais. Os resultados apont …

02.09.2026journal-article

PLOS Global Public Health

Impact of a long-term mentorship program for childbirth providers on quality of care: A cluster randomized controlled trial

Lujia Zhang, Rajet Vatsa, Wei Chang, Sharon Akinyi, Sarah Little, Catherine Gakii, John Mungai, Cynthia Kahumbura, Sathyanath Rajasekharan, Anneka Wickramanayake, Margaret McConnell, Jessica Cohen

Maternal and neonatal mortality rates remain high in sub-Saharan Africa despite increased facility-based childbirth, reflecting persistent gaps in quality of care. We evaluated the impact of MENTORS, a facility based nurse mentorship and training program, on provider knowledge and childbirth care quality. In an unblinded parallel-arm cluster randomized controlled trial conducted between November 2021, 40 health facilities in Kenya were randomized to receive continuing medical education lectures, simulation-based dr …

02.09.2026journal-article

Global Health Cases

Cholera in Zambia: Evaluating Emergency Response and the Limits of Reactive Public Health Systems

Juliet Mwale, Lissa Ceolin

Abstract Cholera remains a recurrent public health challenge in Zambia, with repeated outbreaks disproportionately affecting low-income urban and peri-urban populations, particularly in Lusaka Province. Seasonal rainfall and flooding intensified by climate change repeatedly overwhelm sanitation systems and contaminate water sources. This is particularly true where pit latrines and shallow wells coexist in Lusaka and other flood-prone areas. This case study summarizes the epidemiology and factors associated with cho …

02.09.2026journal-article

Journal of Nursing, Midwifery and Allied Health Sciences

Measurement Equivalence between Pidgin English and Igbo Versions of the Birth Satisfaction Scale–Revised among Postpartum Women in Owerri, Nigeria

Anne Chidinma Nwogu, Ayishetu Musa-Maliki, Yarhere Iroro, Joy Chiamaka Samuel, Josephine Nonye Amadi

Birth satisfaction is an indicator of the quality of intrapartum care, yet evidence on measurement equivalence of birth satisfaction instruments across Nigerian languages remains limited. In multilingual settings such as Nigeria, where Nigerian Pidgin is widely used alongside indigenous languages such as Igbo, establishing cross-language equivalence of patient-reported outcome measures is essential to ensure valid comparison of maternal birth experiences. This study assessed measurement equivalence between the Nige …

02.09.2026journal-article

Healthcare

Digital Health Revolution in Saudi Arabia: A Narrative Review of Healthcare Transformation

Mahmoud Abdel Hameed Shahin

Digital transformation (DT) is a strategic priority for healthcare systems seeking to improve the quality of care, patient safety, and operational efficiency. In Saudi Arabia, DT is central to Vision 2030; however, evidence regarding its effects on healthcare quality and safety remains dispersed across technologies and healthcare settings. This narrative review aimed to examine the impact of digital transformation on healthcare quality and patient safety in Saudi Arabia and to identify the principal implementation …

02.09.2026journal-article

European Journal of Nutrition & Food Safety

Next-generation Probiotics for Human Health: A Critical Narrative Review of Mechanisms, Clinical Translation, Safety and Precision Microbiome Therapeutics

Sandhya Dhyani, Himani Belwal, Neetu Dobhal

The term next-generation probiotic (NGP) is increasingly used for health-associated gut commensals and rationally engineered microorganisms developed from microbiome science rather than from the historical food-fermentation route that produced most conventional probiotics. This expansion has created a translational opportunity, but also a recurrent evidential problem: taxonomic association, mechanistic plausibility, preclinical efficacy, human safety and clinical benefit are often treated as if they formed a single …

02.09.2026journal-article

Transgender Health

Alterations in Breast Tissue Morphology and Androgen Receptor Expression Following Masculinizing Gender-Affirming Hormone Therapy in Transgender Men

Poonpissamai Suwajo, Thawin Techapongsatorn, Adiluck Pisutpunya, Kasama Nilprapha, Jiraroch Meevassana, Apichai Angspatt, Kroonpong Iampenkhae, Saranpong Pornsinsirirak

Purpose: This study aimed to evaluate histological alterations and androgen receptor (AR) expression within breast tissue associated with masculinizing gender-affirming hormone therapy (GAHT) exposure of different duration in transgender men. Methods: A retrospective review of breast histopathological specimens obtained from 81 transgender men following gender-affirming mastectomy between 2017 and 2023 was conducted. Histological features and AR expression were compared between individuals with and without prior GA …

02.09.2026journal-article

Journal of Crop Health

Atmospheric Dynamics and Diversity of Alternaria and Fusarium in a Common Wheat (Triticum aestivum L.) Crop in NW Spain

Kenia C. Sánchez Espinosa, Esperanza Duarte-Escalante, María Fernández-González, María del Rocío Reyes-Montes, Francisco Javier Rodríguez-Rajo

Abstract This study investigated the diversity of Alternaria and Fusarium species in atmospheric aerosols and plant tissue in a common wheat crop in NW Spain. The relationship between atmospheric fungal spore concentrations and weather conditions was analysed. To this end, non-viable and viable aerobiological monitoring methodologies were combined with isolates from plants showing symptoms of fungal infection. The isolates were identified by morphological characterisation and phylogenetic analysis of the 1‑alpha el …

02.09.2026journal-article

Natural Resources for Human Health

Ethnobotany of the Carob Tree (Ceratonia siliqua): Nutritional, Medicinal, and Ecological Significance

SABOUR ALAOUI SANAA

The carob tree (Ceratonia siliqua), a leguminous species native to the Mediterranean basin, holds a prominent place in regional ethnobotany due to its multifaceted uses in traditional diets, natural medicine, and agroecological systems. Belonging to the Fabaceae family, this fruit-bearing tree is appreciated for its nutritional richness: its pulp is high in natural sugars, the seeds contain valuable fats, and the pods are a source of essential minerals such as potassium, calcium, and phosphorus. Moreover, its leave …

02.09.2026journal-article

Discover Public Health

Identifying social structural factors associated with HIV community based organization service use and community participation among women living with HIV in Metro Vancouver

Sagar Pannu, Eva Oberle, Mark Gilbert, Kate Shannon, Colleen Thompson, Desire King, Wiebke Bartels, Haoxuan Zhou, Sherri Pooyak, Kathleen Deering

Abstract Background HIV Community-Based Organizations (CBOs) remain underfunded, limiting programming and support, with limited research examining factors influencing women’s engagement with HIV CBOs. Therefore, social-structural factors associated with HIV CBO service use and community participation were investigated among women living with HIV to inform engagement strategies that optimize resource allocation amid funding constraints. Methods Data were drawn from the Sexual Health and HIV/AIDS: Women’s Longitudina …

02.09.2026journal-article

PLOS One

Retinopathy of prematurity as a clinical marker of developmental vulnerability in preschool children: A nationwide Korean Health Screening study

Tae-Eun Kim, Hye Won Park, Sanghyun Park, Hyun Jin Shin

Purpose To determine the Retinopathy of prematurity (ROP) and its association with developmental delay in Korean preschool children. Methods We conducted a nationwide cohort study using the Korean National Health Insurance Service and National Health Screening Program for Infants and Children (NHSPIC). The study included 808,536 children born 2014–2018 who completed the 7th NHSPIC screening at 54–60 months. Development assessed by the Korean Developmental Screening Test (K-DST) in six domains (self-care, cognition, …

02.09.2026journal-article

British Journal of Healthcare and Medical Research

Associations of Musculoskeletal Pain with Sociodemographic, Health Related, Reproductive Related, Pain Related, Treatment Seeking Pattern and Outcome Among Postmenopausal Women From Dhaka City

Rojina Akter, Abu Sayed Mohammad Giasuddin, Jasim Uddin, Md. Raisul Hassan

Background: The associations (correlations) of Musculoskeletal pain (MSP) with the presenting characteristics in postmenopausal women from Dhaka City are not known; Objectives: To determine the statistical significance of the associations of MSP with the presenting characteristics in postmenopausal women from Dhaka City; Materials & Methods: Statistically further analyses were done for associations of MSP with the presenting features reported in our descriptive cross-sectional study. The SPSS version 22.0 was used …

02.09.2026journal-article

British Journal of Community Nursing

Beyond substitution: advanced primary care nursing for population health

Nia Boughton

Advanced practice roles in primary care have often emerged in response to workforce pressures and service instability, with medical substitution acting as an initial driver. While these origins are important to acknowledge, focusing on substitution alone risks under representing the contributions that advanced primary care nursing makes towards contemporary healthcare challenges. This article argues that advanced primary care nursing has evolved into an integrative, system level form of practice, shaped by populati …

02.09.2026journal-article

The Open Psychology Journal

Investigation of C-reactive Protein (CRP) in Never-Treated Depressed Patients

Hanan Hany Elrassas, Ahmed Saad Mohamed, Nermin Mahmoud Shaker, Marwa Abdel-Rahman Sultan, Tamer Mohamed Sedky Zeidan, Mai Seif ElDin Abdeen

Introduction The relationship between inflammatory markers and depression has been widely debated. C-reactive protein (CRP) is a candidate biomarker for studying such an association. We aim to measure the CRP levels of treatment-naive major depressive disorder (MDD) patients and compare them with those of previously treated MDD patients. Methods This is a cross-sectional study. We recruited 120 patients with MDD; 47 (39.2%) were medication-naïve, while 73 (60.8%) had a history of receiving medication. High-sensitiv …

02.09.2026journal-article

Prävention und Gesundheitsförderung

Von der Ottawa-Charta zur künstlichen Intelligenz

Kevin Dadaczynski, Hajo Zeeb, Orkan Okan

Zusammenfassung Hintergrund Die digitale Transformation ist für die Entwicklung der Gesundheitsförderung und Prävention nicht folgenlos geblieben. Internetbasierte Informations- und Kommunikationstechnologien prägen heute den Alltag von Menschen und eröffnen neue Möglichkeiten zur Förderung von Gesundheit, zur Prävention von Krankheiten sowie zur Unterstützung gesundheitsbezogener Entscheidungen. Ziel und Methode Der Beitrag verfolgt das Ziel, die Entwicklungslinien der digitalen Gesundheitsförderung und Prävention …

02.09.2026journal-article

Journal of Psychosexual Health

Comprehensive Sexuality Education (CSE) in India: Decoding Parental Views and Understanding

Likith R S, Vigneshwaran Subbiah Akkayasamy

Objectives: To explore parental attitudes toward comprehensive sexuality education (CSE), assess their willingness to discuss sexuality-related topics with their children, and generate evidence to support policy advocacy for age-appropriate CSE in Indian schools. Method: A cross-sectional quantitative study was conducted among 113 parents from rural and urban India using a self-administered questionnaire. Descriptive analysis was performed. Results: Parents generally expressed positive attitudes toward CSE; however …

02.09.2026journal-article

Health Services Research

Delivery Timing, Out‐Of‐Pocket Maternity Costs, and Postpartum Care Utilization: An Instrumental Variable Analysis Among Commercially Insured Women

Rebecca A. Gourevitch, Jessica L. Cohen, Tara Shakley, Sung Min Park, Mary Beth Landrum, Meredith B. Rosenthal, Mark W. Friedberg, Anna D. Sinaiko

ABSTRACT Objective To examine whether out‐of‐pocket costs during pregnancy and delivery affect use of postpartum care. Study Setting and Design Because health insurance deductibles and limits reset annually, the timing of childbirth within that year quasi‐randomly assigns people to different levels of cost‐sharing during pregnancy+delivery versus postpartum. We use a novel instrumental variable approach that leverages this variation to analyze whether higher maternity spending due to delivering early in the plan ye …

02.09.2026journal-article

Environmental Science and Pollution Research

Integrated physical-chemical remediation and human health risk assessment of multi-metal contaminated industrial soils

Lucia Marsich, Alessio Ferluga, Luca Cozzarini, Paolo Bevilacqua

Abstract This study presents an integrated remediation strategy and human health risk assessment for multimetal-contaminated industrial soil. The sequential treatment combined mechanical screening, high-intensity magnetic separation (HIMS), and chemical extraction using ethylenediaminetetraacetic acid (EDTA). Initial characterization revealed extreme contamination levels, with cadmium and thallium posing significant noncarcinogenic risks, particularly for children (hazard index = 169.4). Physical separation proved …

02.09.2026journal-article

Natural Resources for Human Health

Rosa multiflora Thunb.: Chemical composition, potential pharmaceutical applications, and future research directions

Le Pham Tan Quoc, Pham My Hao, Pham Thi Quyen, Lam Bach Bao Phuong

<i>Rosa multiflora</i> Thunb., is a widely distributed plant species of the Rosaceae family and used in traditional medicine in many Asian countries. In recent years, this species has attracted increasing attention in the field of medicinal research due to its high content of bioactive compounds. This article aims to systematically evaluate the morphological characteristics, secondary chemical constituents, and major biological activities of <i>R. multiflora</i>, such as antioxidant, antibacterial, and anti-inflamm …

02.09.2026journal-article

Health Physics

Measurement of Radon Levels and Radiological Risk Assessment of Borehole Water in Oil-Producing Area of Ukwuani, Southern Nigeria

Augustine Onyema Nwabuoku

A number of communities in Ukwuani Local Government Area of Delta State are known to host several crude oil companies with exploration activities ongoing and may be responsible for the presence of high radon levels in drinking water. Radon ( 222 Rn) has emerged as a major health concern due to its radiotoxic effects and radiation dose to internal organs. Therefore, this work aimed to measure radon levels in borehole water and assess the radiological risk. Thirty water samples were collected from borehole sources in …

02.09.2026journal-article

Scandinavian Journal of Public Health

Wellbeing, mastery and work participation: Effects of the Five Ways to Wellbeing course—a randomized controlled trial

Maja Eilertsen, Nikolai O. Czajkowski, Tone K. Omsland, Espen Røysamb, Ragnhild Bang Nes

Background: Rising ill health, declining wellbeing, and absenteeism threaten societal sustainability amid an ageing population. Promoting health, wellbeing and work participation is essential. The Five Ways to Wellbeing course is a six-week programme designed to enhance wellbeing through five core activities: connecting, being active, taking notice, learning, and giving. A digital, shorter version has shown effectiveness in the general population, but the physical course has not been evaluated by randomized control …