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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
02.09.2026journal-article

Environment & Health

Proteomic Signatures of Multiple Environmental Exposures and the Risk of COPD

Yiqun Zhu, Yao Wu, Yan Tan, Zhuanxing Zhu, Huaying Liang, Qinyu Chang, Fengyu Lin, Dianwu Li, Jun Cheng, Pinhua Pan, Yan Zhang, Yuming Guo

Abstract Environmental factors such as air pollution, ambient temperature, and socioeconomic status are associated with chronic obstructive pulmonary disease (COPD), yet the potential role of proteomic alterations remains unclear. We aim to identify circulating proteomic signatures related to distinct environmental exposures and evaluate their associations with incident COPD. We analyzed 42,445 participants from the UK Biobank with baseline plasma proteomic profiling and 21 environmental exposure assessments. Expos …

02.09.2026journal-article

Annals of Global Health

Implementation and Access Gaps in Infectious Disease Screening for Migrants in Europe: A Structured Review with Thematic Synthesis From the ESGITM Group

Rosa Buonamassa, Nikolaos Markou-Pappas, Alberto Matteelli, Ferenc Balázs Farkas, Muhammad Asaduzzaman, Luisa Frallonardo, Botond Lakatos, Annalisa Saracino, Alba Cuxart-Graell, Nathan Bertelsen, Christian Wejse, Alexandre Raphael Meduri, Giacomo Guido, Irene Losada, Pietro Locantore, Roberta Iatta, Caroline Rönnberg, Francesco Di Gennaro

Background: Infectious disease screening is widely recommended for migrants in Europe, yet implementation remains inconsistent across countries and settings. While guidance has focused on which infections to screen for, less attention has been paid to how screening is delivered, accessed, and linked to care. This structured review with thematic synthesis aimed to synthesize evidence on implementation gaps, barriers, and facilitators, with particular attention to differences across the migratory cycle. Methods: A st …

02.09.2026journal-article

International Journal of Molecular Sciences

NLRP3 Regulation in Neonatal Hypoxic–Ischemic Encephalopathy—Focus on Microglial Activation

Hannah Burkard, Maria Eugenia Bernis, Anna-Sophie Bremer, Elke Maes, Jonas Walter, Felix Meissner, Hemmen Sabir

Neonatal hypoxic–ischaemic encephalopathy (HIE) is a major cause of neonatal mortality and long-term neurological disability, affecting 1–3 per 1000 live births in developed countries and occurring at substantially higher rates in developing countries. Neuroinflammation is a key contributor to disease progression, with growing evidence implicating the activation of the NLR family pyrin domain containing 3 (NLRP3) inflammasome following hypoxic–ischaemic (HI) injury. In this study, we investigated the role and regul …

02.09.2026journal-article

Pediatrics

Measurement Properties of Delirium Tools in Pediatric Intensive Care: A Systematic Review

Max Zilezinski, Natascha-Elisabeth Denninger, Martin Müller, Antje Tannen, Jan Kottner

CONTEXT Delirium is common in pediatric intensive care units. Reliable tools are needed, but evidence on measurement properties remains fragmented. OBJECTIVES To identify pediatric delirium tools and evaluate their measurement properties and certainty of evidence. DATA SOURCES MEDLINE, EMBASE, PsycINFO, CINAHL, Cochrane Library, and Web of Science were searched without language or date restrictions. STUDY SELECTION Original observational, cross-sectional, and validation studies evaluating at least 1 measurement pro …

02.09.2026journal-article

BMC Medical Ethics

From creation to dissemination: a lifecycle-based evaluation of AI guidance policies in health-related journals

Yifan Zhu, Jin Zhang, Ye Chen, Yanyan Wang, Yuehua Zhao

Abstract Background The rapid integration of generative artificial intelligence into health sciences research has prompted major advisory bodies to establish ethical guidelines governing AI use in scholarly publishing. However, practical implementation at the journal level remains inconsistent, with considerable incongruence observed between individual journal policies and overarching publisher mandates. This study conducts a comprehensive analysis of AI guidance policies in international health-related journals to …

02.09.2026journal-article

International Journal of Medicine and Health

Association Between Ultra-Processed Food Consumption and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Adults

Lila Amila, Kurnia Agustina Sitompul, Maretha Primariayu, Dalilah Salsabila Salma, Siti Aria Rahmani Novianto, Marsha Zahrani, Nadia Mardiana Hudan

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease globally, but its association with ultra-processed food (UPF) consumption under the new diagnostic framework has not been systematically synthesized. We systematically searched PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science for observational studies examining habitual UPF intake (NOVA classification) and MASLD/NAFLD in general adult populations using validated outcome ascertainment. Qualit …

02.09.2026journal-article

Journal of Public Health and Preventive Medicine

Remote and Hybrid Work and Sedentary Behaviour Among Working Adults: A Scoping Review of Behavioural Evidence and Cardiometabolic Research Gaps

siying qiu, hanyu du, Yuexian Tao

Background: Remote and hybrid work arrangements may improve autonomy and reduce commuting, but may also reduce routine movement and promote prolonged sitting. Evidence on sedentary behavior in these settings has expanded, whereas direct evidence on cardiometabolic outcomes remains limited. Objective: To map behavioral evidence on sedentary exposure in remote and hybrid work, describe its measurement and distribution across work arrangements, and characterize cardiometabolic outcomes as an evidence gap. Methods: We …

02.09.2026journal-article

Community Health Equity Research & Policy

Lessons learned from community approaches to COVID-19 prevention: a qualitative study with transgender adults in the United States

Robynn Ashenden, Eunice Okumu, Dee Adams, Carter Brown, Marissa Miller, Sari Reisner, Andrea L. Wirtz, Tonia Poteat

The COVID-19 pandemic prompted widespread public health measures, including non-pharmaceutical (NPIs) and pharmaceutical interventions (PIs). This study explores the prevention strategies adopted by transgender individuals and examines how structural and attitudinal factors shaped their uptake within trans-specific healthcare and social contexts. As part of the LITE Connect mixed-methods study (N = 2,092), 30 participants engaged in qualitative, semi-structured interviews between October 2021 and June 2022. Content …

02.09.2026journal-article

Scientific Reports

Efficacy of a self-guided online resilience intervention for improving mental health among university students: A randomized controlled trial

Sonja Bartelt, Tabea Werner, Lisa von Boros, Sarah K. Schäfer, Friederike Koehler, Benedikt E. Wirth, Klaus Lieb, Oliver Tüscher, Michèle Wessa

Abstract Epidemiological data indicates that university students are an at-risk population for the development of mental disorders. Online interventions have been proposed as promising tools for reducing barriers to treatment and establishing easily accessible health-care services promoting mental health and resilience. This study investigated the efficacy of a Learning Management System (LMS)-based self-guided online resilience intervention. 216 university students took part in a randomized controlled trial with a …

02.09.2026journal-article

Journal of Nursing, Midwifery and Allied Health Sciences

Providers’ Perceived Benefits and Implementation Challenges of Midwife-Led Continuity of Care at Primary Health Facilities in Rivers State, Nigeria

Patience Ibe, Eunice Osuala, Samuel Onuoha, Chinemerem Eleke

Midwife-led continuity of care (MLCC) is globally recognized for improving maternal and neonatal health outcomes through continuous and personalized care. This study examined the perceived benefits and implementation challenges of MLCC among healthcare providers in selected health facilities in Rivers State, Nigeria. A parallel convergent mixed-methods design was employed. The study was conducted in four primary healthcare centres: Orogbum, Ozuoba, Aluu, and Omoku. For the qualitative component, 16 key healthcare p …

02.09.2026journal-article

Frontiers in Digital Health

Multimodal medical diagnosis: a mini review of LLM–vision fusion models in low-resource healthcare settings

Kahakashan Ashraf, Md. Hamid Hosen, Nuzhat Tabassum Farah, Md Kishor Morol, Tze Hui Liew, Dip Nandi, Mashiour Rahman, Abdullah Al Jubair

Recent advances in large language models (LLMs) and vision transformers have enabled multimodal systems that integrate clinical text with medical imaging for diagnostic decision-making. While these systems show promising results on benchmark datasets in well-resourced research settings, their applicability in low-resource healthcare environments where diagnostic disparities are most severe remains limited and poorly understood. This mini review synthesizes key developments in LLM–vision fusion architectures from 20 …

02.09.2026journal-article

JTH: Journal of Technology and Health

SPIRITUALITY IN PATIENTS WITH ACUTE CORONARY SYNDROME (ACS): A LITERATURE REVIEW

Husnul Khotimah, Luthfiyyah Khanuun

Beyond its physical impact, Acute Coronary Syndrome (ACS) significantly disrupts a patient's psychological equilibrium. Incorporating spirituality into patient care offers a potential avenue for coping and facilitating holistic rehabilitation. This study synthesized current evidence regarding how spiritual factors and targeted spiritual care influence psychological and clinical outcomes in ACS cohorts. Following PRISMA 2020 protocols, a systematic search of PubMed, Scopus, and Google Scholar yielded 11 eligible ori …

02.09.2026journal-article

Clinical Journal of the American Society of Nephrology

Associations of Plant- and Animal-Sourced Ultra-Processed Foods and Incident CKD in the Cardiovascular Health Study

Courtney M. Hill, Alyssa Feinberg, Casey M. Rebholz, Rozenn Lemaitre, Amanda M. Fretts, Kerri L. Wiggins, Nona Sotoodehnia, James S. Floyd, Benjamin Lidgard, Nisha Bansal, Bruce M. Psaty, Hyunju Kim

Background: Ultra-processed foods (UPFs) are associated with adverse health. Plant foods can be highly processed. It is not clear whether plant- and animal-sourced UPFs are associated chronic kidney disease (CKD) risk. Methods: Data came from the Cardiovascular Health Study, a prospective cohort of 2,661 older adults (≥65 years). The exposure was UPF intake, classified as plant- or animal-sourced in servings/day using the Nova framework from food frequency questionnaires (1989-1990, 1995-1996). The outcome was inci …

02.09.2026journal-article

International Journal of Environmental Research and Public Health

Sustaining Mana in Mate Wareware Care: Whānau Perspectives

Kirsten Robertson (Kāi Tahu), Tui Kaitai-Martin (Kāi Tahu), Rob Thomson, Diane Ruwhiu (Ngā Puhi), Maree Thyne

Māori experience inequities in the recognition of mate wareware and in access to dementia and aged care support in Aotearoa New Zealand. Less is known about how whānau experience supporting a whānau member with mate wareware, what support they find helpful, and what they consider important for mate wareware-friendly communities. This kaupapa Māori qualitative study involved a co-design phase with seven kaumātua, which informed the study questions and whānau hui guide, followed by ten in-depth whānau Māori hui invol …

02.09.2026journal-article

Africa Journal of Nursing and Midwifery

Exploring Psychological Support Systems in Mental Health Units: An Interpretive Phenomenological Study of Nurses’ Post-traumatic Clinical Incident Lived Experiences

Magdalena Karomo, Dr Daniel Opotamutale Ashipala

Background: Nurses often face traumatic events in clinical settings, leading to significant psychological, physical and professional consequences. Understanding their lived experiences, coping strategies, and institutional support is essential for designing effective, culturally sensitive interventions that protect their well-being and promote safe patient care. Objective: The objective of this study was to explore the lived experiences of nurses exposed to a traumatic clinical incident, focusing on its psychologic …

02.09.2026journal-article

Journal of Tropical Health

Prevalence of Gastroesophageal Reflux Disease and Its Impact on Quality of Life Among Medical Undergraduates at the University of Jaffna, Sri Lanka

Manori Vijaya Kumari

Introduction: Gastroesophageal reflux disease (GERD) may affect student well-being and daily functioning. Medical undergraduates may be vulnerable to GERD because of academic stress, irregular meal patterns, and lifestyle factors. However, limited data exist on its prevalence and its impact on the quality of life in this group. This study aimed to determine the prevalence of GERD and its impact on the quality of life among medical undergraduates.Methods: A cross-sectional study was conducted among medical undergrad …

02.09.2026journal-article

Developmental Medicine & Child Neurology

Maternal depression as a mediator of preterm birth and child development

Ashish KC, Miriam Sophia Meier, Jaya Chandna, Lea Kreyenbaum, Carin Andrews, Omkar Basnet

Abstract Aim To assess the causal pathway between preterm birth and infant neurodevelopmental delay, with maternal depression as the mediator using a counterfactual mediation framework. Method A prospective cohort of 1253 mother–infant pairs were enrolled and followed up until 6 months in Nepal. Preterm birth was assessed using medical birth register; maternal depression and infant neurodevelopmental delay were assessed using maternal interview. Causal mediation analysis was performed using logistic regression mode …

02.09.2026journal-article

Revista Interdisciplinar de Estudos em Saúde

Judicialização da saúde e perfil de usuários hipossuficientes na Fronteira Oeste do RS: Um Estudo Transversal Censitário

Thiago Gargaro Zamarchi, Amanda Fontoura de David, Augusto Renner Muller, Aline Kruger Batista, Letícia Silveira Seerig, Lenise Menezes Seerig

Compreender o perfil epidemiológico, as principais motivações e quantificar o número de usuários que buscam a Defensoria Pública (DP) nas demandas judiciais ligadas à saúde considerando a seguinte questão de pesquisa: qual o perfil epidemiológico dos usuários que recorrem à DP em demandas relacionadas à saúde e qual a participação da instituição na garantia do direito à saúde? Trata-se de um estudo transversal, descritivo, tipo censo, baseado em dados secundários das ações ajuizadas na DP de um município da Frontei …

02.09.2026journal-article

Nutrition and Health

Preconception nutritional supplementation and behavioral interventions and their association with maternal and neonatal health: A systematic review and meta-analysis

Salima Meherali, Yared Asmare Aynalem, Saba Nisa, Megan Kennedy, Zohra S. Lassi

Background Preconception health influences pregnancy outcomes, with poor nutrition and health-related behaviors linked to anemia, preeclampsia, and fetal growth restriction. Despite increasing attention to these adverse outcomes, evidence on preconception nutritional and behavioral interventions remains limited, fragmented, and inconsistently synthesized. Objectives To synthesize evidence on the role of preconception nutritional supplementation and behavioral interventions in supporting maternal and neonatal health …

02.09.2026journal-article

Rehabilitation Oncology

Parental Awareness of Preventive Health Practices and Health-Related Quality of Life in Children with Cancer

Müberra Tanriverdi, Güleser Güney Yilmaz, İrem Nur Usluer, Hafize Reyhan Çalikuşu, Fatma Betül Çakir

Background: This study aimed to examine parents’ awareness of health promotion and preventive care in childhood cancer and to investigate whether children’s HR-QoL (Health-Related Quality of Life) differs according to parental awareness items. Methods: This prospective cross-sectional study included 76 parents of children aged 0 to 18 years diagnosed with cancer and followed at a pediatric hematology/oncology clinic. Parents completed a Demographic Information Form, the Barratt Measure of Social Status, the Pediatr …

02.09.2026journal-article

Perspectives of the ASHA Special Interest Groups

Decolonizing the Child Language Curriculum for Speech-Language Pathologists: A Framework for Transformative Practice

Mershen Pillay, Sarah Spencer, Aydan Suphi, Lindsey Thiel, Dharinee Hansjee, Harsha Kathard

Purpose: Speech and language therapy education has traditionally relied on Euro-American-centric theories of child development. This tutorial examines how child language acquisition curricula can be transformed through decolonization frameworks to better prepare practitioners for culturally responsive practice. Method: Drawing on critical conversations methodology and international collaborative experiences across the United Kingdom, New Zealand, and South Africa, we propose practical recommendations for curriculum …

02.09.2026journal-article

Natural Resources for Human Health

Phytochemical Profiling, Optimization of Extraction Methods, and Biological Activities of Buxus sempervirens Leaves

Muskan Bhardwaj, Garima Garg, Brij Mohan Sharma

The leaves of Buxus sempervirens contain numerous phytochemical compounds such as alkaloids, flavonoids, and tannins that possess significant medicinal properties and have industrial uses as well. This study was conducted to identify optimum conditions for extracting bioactive compounds from the plant and to assess their biological activities. In the current study, bioactive compounds were extracted from the leaves of B. sempervirens using the Soxhlet extraction method employing ethanol and methanol as solvents. Fo …

02.09.2026journal-article

Natural Resources for Human Health

Formulation and In Vitro Evaluation of Meloxicam-Loaded Transdermal Patches: Effect of Polymeric Blends on Drug Release and Kinetics

Ameen M. Alwossabi, Imad M. Taj Eldin, Ahmed M. Al-Ghani, Mohammed Abdelrahman, Ahmed Ashour, Wadah Osman, Mohammed Hamed Alqarni, Ahmed I. Foudah, Mohamed Abdel-Monem El- Sakhawy, Reham M. Samra

Meloxicam taken orally is linked to adverse reactions in the gut and varying bioavailability because of first-pass metabolism. Because they allow for prolonged drug release and increased therapeutic efficacy, transdermal drug delivery systems (TDDS) offer a promising alternative. Using various polymeric blends, the current work sought to create and assess meloxicam-loaded transdermal patches in order to maximize their physicochemical characteristics and drug release behavior. Polyvinyl alcohol or polyvinylpyrrolido …

02.09.2026journal-article

Healthcare

Self-Reported Knowledge and Awareness of Musician-Related Disorders Among Music Educators and Pre-Service Music Teachers in Higher Education Institutions in Türkiye: An Occupational Health Literacy Perspective

Rıza Akyürek, Ayşe Şevval Dinçer

Background/Objectives: Musicians face occupational health risks from repetitive movement, sustained posture, and intensive practice. This study examined self-reported knowledge of musician-related disorders, physical complaints, and selected health practices among music educators and pre-service music teachers, using occupational health literacy (OHL) as an interpretive framework. Methods: A cross-sectional survey included 432 participants from public higher education institutions in Türkiye (83 educators; 349 pre- …