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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Frontiers in Medicine

Case Report: Soft endoscopic treatment of Herlyn–Werner–Wunderlich syndrome: an innovative clinical procedure for hymen preservation

Yonghua Tian, Wei Fu, Yan Geng

Background Herlyn–Werner–Wunderlich syndrome (HWWS) management typically requires hymenotomy. We describe the fully endoscopic, hymen-sparing septotomy in a patient with no history of sexual intercourse. Case presentation A 20-year-old patient with no prior sexual intercourse and progressive dysmenorrhea was diagnosed by MRI with HWWS, presenting as uterus didelphys, obstructed right hemivagina, and left renal agenesis. A 9-mm flexible gastroscope and endoscopic submucosal dissection (ESD) knives were introduced th …

03.09.2026journal-article

Frontiers in Neurology

Pediatric stroke in inborn errors of metabolism: clinical characteristics, neuroimaging features, and short-term outcomes

Javeria Raza Alvi, Areeba Wasim, Saher Gul Ahdi, Tipu Sultan, Muhammad Zia-ur-Rehman, Khalid Al-Thihli, Fathiya Al Murshedi, Amna Al Futaisi

Introduction Pediatric stroke has a broad etiological spectrum, with inborn errors of metabolism (IEM) increasingly recognized as an important and potentially treatable cause. This study aimed to characterize the clinical, radiological, and electroencephalographic features of IEM-related pediatric stroke and to evaluate short-term functional outcomes. Methods This prospective cohort study was conducted at The Children’s Hospital Lahore, Pakistan, and Sultan Qaboos University Hospital, Muscat, Oman (January 2024–Dec …

03.09.2026journal-article

BANKING LAW

LEGAL REGULATION OF INFORMATION QUALITY IN BANKING AND PUBLIC ADMINISTRATION

Oksana V. Shmaliy, Artem A. Oliferenko

The article analyzes the legal significance of information quality for banking activities in the context of credit institutions’ use of official information, state data, derivative datasets and anonymized information. It is shown that such information is used for client identification, banking risk assessment, fraud detection and the application of algorithmic models. Insufficient quality of the information basis may affect the correctness of banking decisions, the reliability of automated processing and the verifi …

03.09.2026journal-article

Culture: Management, Economics and Law

Archaeological Heritage Sites: On the Balance of Private and Public Interests

Yulia S. Zubenko

The article examines the actual problem of the balance of private and public interests related to the protection and use of archaeological heritage sites. The author analyzes the legal mechanisms governing the interaction of private owners and the state in the field of historical heritage preservation. Judicial practice is discussed, illustrating the complex legal and ethical issues that arise when applying legislation on archaeological heritage sites. The article also focuses on the need to improve legal regulatio …

03.09.2026journal-article

An Idea Health Journal

Factors Associated the Perceived Effectiveness of Seven-Jumps Problem with Based Learning Tutorials among Nursing Students: A Mixed-Methods Study

Ika Purnamasari, Candra Dewi Rahayu, Anisa Ell Raharyani

Background: Seven-Jumps Problem-Based Learning (PBL) tutorials are commonly implemented in nursing education to foster active learning, critical reasoning, and collaborative problem-solving. However, evidence on factors influencing students’ perceptions of tutorial effectiveness remains limited in Indonesian nursing education. Methods: An explanatory sequential mixed-methods design was employed. The quantitative phase included 70 fourth-semester undergraduate nursing students and utilized the Tutorial Group Effecti …

03.09.2026journal-article

Revista de Ciencias Tecnológicas

Análisis de riesgo a la salud humana por ingesta de arsénico presente en agua purificada en Zinapécuaro, Michoacán: Un enfoque probabilístico

Alexis Calderón Herrera, Marco Antonio Martínez Cinco, José Leopoldo Mendoza Lagunas, Laura Nelly Rodríguez Cantú, María Mercedes Meza Montenegro, María del Mar Navarro Farfán, Jesús Ávila Guzmán

El arsénico (As) como elemento tóxico se encuentra de manera natural regiones geotérmicas de México. En el área de Zinapécuaro, ubicado en Michoacán se han detectado concentraciones que superan la norma de salud de 10 μg/L, particularmente en las aguas subterráneas y de manantial. En este estudio se realizó el muestreo en 6 diferentes negocios de recarga de agua para determinar las concentraciones de arsénico inorgánico presente. El objetivo del trabajo es evaluar el riesgo para la salud humana, particularmente en …

03.09.2026journal-article

Frontiers in Public Health

Staff-mediated doll therapy in Chinese residential dementia care: an exploratory pilot and feasibility mixed-methods cluster randomized clinical trial

Zhenti Cui, Rongrong Guan, Tianrui Xue, Yongchang Sun, Maw Pin Tan, Mas Ayu Said, Yingdong Cao

Background Doll therapy is a person-centered intervention for behavioral and psychological symptoms of dementia, but evidence from Chinese nursing homes and information about implementation, medication use, and ethical acceptability remain limited. Methods We conducted an exploratory pilot and feasibility mixed-methods cluster-randomized clinical trial in six nursing homes in Zhengzhou, China. Homes were randomized 1:1 to a staff-mediated doll-therapy care package plus routine care or routine care alone. Residents …

03.09.2026journal-article

Frontiers in Public Health

Physical activity perceptions, barriers, and needs among nursing home residents: an explanatory sequential mixed-methods study

Jung-A. Kim, Haeyeon Kim, Hye-Young Jang

Background/objectives Physical activity is essential for maintaining health and preventing functional decline among older adults residing in nursing homes. However, engagement in physical activity remains suboptimal in this population due to multifactorial influences. This study aimed to examine the perceptions, barriers, and needs related to physical activity among nursing home residents. Methods An explanatory sequential mixed-methods design was employed from September to December 2024. In the quantitative phase, …

03.09.2026journal-article

Frontiers in Medicine

Clinical efficacy of the Galdakao-modified supine Valdivia position vs. the lithotomy position in FANS-UAS-assisted IPC-RIRS for renal calculi

Qiuhua Zhu, Yunxia Cai, An Wang, Jiansheng Xiao, Leming Song, Tairong Liu, Hua Chen

Objective To evaluate the clinical efficacy and safety of a modified Galdakao-modified supine Valdivia (GMSV) position combined with a flexible and navigable suction ureteral access sheath (FANS-UAS) in intelligent pressure-controlled retrograde intrarenal surgery (IPC-RIRS) for the treatment of renal calculi. Methods This single-center retrospective cohort study included 158 patients with renal calculi who underwent FANS-UAS-assisted IPC-RIRS between June 2023 and June 2025. Patients were categorized into the GMSV …

03.09.2026journal-article

Frontiers in Cardiovascular Medicine

Novel predictors of late recurrence after catheter ablation for atrial fibrillation: from biomarkers to artificial intelligence models

Chiyu Chen

Atrial fibrillation (AF) is the most common sustained arrhythmia, and catheter ablation is an established rhythm-control strategy. However, late atrial arrhythmia recurrence remains common, limiting long-term procedural benefits. This review provides a structured and critical overview of current evidence on the predictors of late recurrence after AF catheter ablation across four domains: circulating biomarkers, imaging and electrophysiological substrate markers, genetic susceptibility, and artificial intelligence a …

03.09.2026journal-article

Frontiers in Oncology

Case Report: Iparomlimab and Tuvonralimab-based therapy for epithelioid malignant peritoneal mesothelioma: a three-case series

Zhijin Xu, Lehe Zhu, Ying Fang, Yiyan Jiang

Background Epithelioid malignant peritoneal mesothelioma (EMPM) is a rare and aggressive malignancy of serosal origin. Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy is generally reserved for carefully selected patients in whom adequate cytoreduction appears feasible, while evidence supporting systemic immunotherapy remains limited for patients with unresectable disease or those unable to tolerate intensive treatment. Iparomlimab and tuvonralimab (QL1706) is a fixed-ratio anti-PD-1/an …

03.09.2026journal-article

Frontiers in Public Health

The need for measurable targets in national action plans on antimicrobial resistance: opportunities for action

Uswa H. Shafaque, Arne Ruckert, Samuel Orubu, Kayla Strong, Suzanne Garkay Naro, Susan Rogers Van Katwyk, Mathieu J. P. Poirier

Antimicrobial resistance (AMR) represents a significant global health challenge that defies simple solutions and requires multisectoral coordination and interdisciplinary collaboration. National action plans (NAPs), which are built on the template of the World Health Organization’s Global Action Plan on AMR, offer a critical framework for addressing AMR. However, the lack of measurable targets within many NAPs hinders progress in mitigating AMR and setting up accountability and monitoring frameworks for tracking im …

03.09.2026journal-article

Frontiers in Oncology

The expression and clinical significance of SIRT5, H2A and TOP2A in cervical cancer

Fenghu Li, Xue Tian, Fan Mei, Yanjun Du, Lili Hu, Jiehui Li, Shengfa Su, Bing Lu

Objective To analyze the correlation between the expression of lysine deacetylase 5 (SIRT5), histone H2A and topoisomerase IIα (TOP2A) protein with clinical stage and survival in cervical cancer. Methods The expression levels of SIRT5, H2A and TOP2A proteins were detected by immunohistochemical two-step method in paraffin-embedded tissue blocks from 65 patients with cervical cancer (21 cases of stage IB, 9 cases of stage IIA and 35 cases of stage IIIC1p). The expression distribution and positive rate of SIRT5, H2A …

03.09.2026journal-article

Health Promotion Journal of Australia

Food Processing Knowledge in Relation to Healthiness and Self‐Reported Understanding of the Health Star Rating in Australia

Jacqueline Penney, Tailane Scapin, Adrian J. Cameron, Christine M. White, David Hammond, Clara Gomez‐Donoso

ABSTRACT Issue Addressed This study aimed to examine Australians' food processing knowledge in relation to food healthiness and self‐reported understanding of the Health Star Rating (HSR), their association, and sociodemographic differences. Methods An online survey was completed by 3760 adults in Australia as part of the 2021 International Food Policy Study. Participants rated the healthiness of foods across four categories (grains, meat, dairy, fish), with three products presented per category representing increa …

03.09.2026journal-article

Emergency Medicine Australasia

Criteria for Safe Hospital Discharge in Bronchiolitis: A Systematic Review

Meredith L. Borland, Kate Loveys, Franz E. Babl, Elizabeth Cotterell, Libby Haskell, Sharon O'Brien, Ed Oakley, Emma J. Tavender, Catherine L. Wilson, Stuart R. Dalziel, the Paediatric Research in Emergency Departments International Collaborative (PREDICT) Network

ABSTRACT Bronchiolitis is the leading cause of hospital presentation and admission for infants in Australasia. We aimed to synthesise current evidence on the effect of discharge criteria for infants (aged < 12 months) who are presenting to or are admitted to hospital with bronchiolitis, to inform a binational guideline recommendation update. Systematic searches were conducted on MEDLINE, EMBASE, PubMed, Cochrane Library and CINAHL (last search 19 February 2025) for non‐randomised studies evaluating hospital dischar …

03.09.2026journal-article

Frontiers in Digital Health

Hardware-aware knowledge-distilled CNN for real-time classification of plaque-associated angiographic findings on FPGA

Nazarkar Pravalika, Jabeena Afthab, Vetriveeran Rajamani

Coronary artery disease (CAD) is one of the leading causes of global mortality, necessitating accurate assessment of coronary artery stenosis and plaque-associated angiographic findings from coronary angiography images. Although deep learning-based diagnostic models have demonstrated high predictive capability, their deployment on resource-constrained embedded platforms remains challenging because of computational complexity and memory requirements. To address these limitations, this study proposes a knowledge-dist …

03.09.2026journal-article

Frontiers in Psychology

When chatbots are perceived as “understanding”: a study on how virtual agent persona styles and affective interaction promote mental health acceptance

Qi Wu, Shizhu Lu, Yuqi Yan, Lin Liu, Xiaojie Peng

Introduction Mental health challenges among university students have become increasingly prevalent, while existing digital interventions often struggle to sustain user engagement and provide meaningful emotional support. Although previous studies have proposed various explanations for the limited acceptance of AI-based mental health chatbots, the role of affective experience remains insufficiently understood. This study proposes an affect-centered framework to examine how different virtual agent persona styles (Lis …

03.09.2026journal-article

Clinical Chemistry and Laboratory Medicine (CCLM)

Toward harmonized reporting of Alzheimer’s disease biomarkers in clinical practice

Luisa Agnello, Andrea Pilotto, Lorenzo Gaetani, Giovanni Bellomo, Valentina Bessi, Marco Bozzali, Annachiara Cagnin, Angelo Labate, Federico Massa, Fabio Moda, Roberto Monastero, Giulia Musso, Tommaso Piccoli, Giulia Sancesario, Lucilla Parnetti, Alessandro Padovani, Marcello Ciaccio

Abstract Cerebrospinal fluid biomarkers, and more recently blood-based biomarkers, are playing a pivotal role in reshaping the clinical management of neurodegenerative diseases, supporting early detection, biological diagnosis, patient stratification, prognostic assessment, therapeutic decision-making, and longitudinal disease monitoring. To effectively support clinical decision-making, biomarker measurements must be communicated in a standardized, transparent, and clinically interpretable manner. Despite internati …

03.09.2026journal-article

International Journal of Legal Medicine

Hypothermia and cold injuries – rare but severe manifestations of child abuse and neglect

L. Küppers, S. Ritz, L. M. König

Abstract Background While thermal injuries caused by heat are well-recognized in cases of child maltreatment, injuries resulting from cold exposure (hypothermia and local cold injury) appear to be rare in this context. Although hypothermia and cold injuries related to child abuse and neglect pose a significant threat to affected children, systematic data on this topic are currently lacking. The goal of this article was to better understand the frequency, forms and contexts of child maltreatment involving cold expos …

03.09.2026journal-article

Clinical and Experimental Dermatology

Uncommon benign tumour of the scalp

Peter Robinson, Sam Cook, Stephanie Ball, Fraser Charlton, Neil Rajan

A 37-year-old male (Fitzpatrick skin type III) presented with a 10-month history of an enlarging nodule on the right parietal scalp. There was a paternal history of melanoma, but no family history of similar skin lesions. Physical examination revealed an ill-defined, pink, round, non-tender, mobile nodule measuring 15 x 15 mm. A second similar papule measuring 6 x 5 mm was found at the right scalp apex.

03.09.2026journal-article

European Geriatric Medicine

Improving diabetes management in older adults with cancer: a quality improvement project to enhance monitoring during steroid-based systemic anti-cancer therapy

Evelyne Liuu, Rose Evans, Nathanael Bassas-Letissier, Gitanjali Amaratunga, Sarah Compton, Alexandros Georgiou, Tania Kalsi, Yuk-Fun Liu, James Maguire, Clare Nottage, Hannah L. Rush, Carly Welch

Abstract Purpose Older adults undergoing systemic anti-cancer therapy (SACT) with steroids are at high risk of developing steroid-induced hyperglycaemia (SIH). However, monitoring and management remain inconsistent. This quality improvement project (QIP) involved developing and evaluating the GOLD diabetes enhanced monitoring pathway, a multidisciplinary, age-adapted initiative for older patients at intermediate SIH risk. Methods The pathway was implemented at Guy’s and St Thomas’ NHS Foundation Trust between Febru …

03.09.2026journal-article

Frontiers in Public Health

Understanding the needs of employees with non-communicable diseases regarding physical activity-related workplace health promotion programs: a qualitative study

Andrea Schaller, Lena Katharina Spanio, Martin Lange

Introduction The prevalence of non-communicable diseases (NCD) is rising and increasingly affects people of working age. Thereby, NCD burden those affected and challenge society, welfare systems and companies in many different ways. Workplace Health Promotion (WHP) is considered promising to improve and maintain employee health and physical activity (PA)-related WHP programs constitute a main area of action. This study aimed to better understand the needs employees with NCD have with regard to PA related WHP progra …

03.09.2026journal-article

Frontiers in Cardiovascular Medicine

A clinical prediction model for post-procedural hemolysis after transcatheter VSD closure in children

Jingyi Tian, Xinru Gan, Dan Yin, Huichao Sun, Ping Xiang, Mi Li

Background Transcatheter closure has been widely used for the treatment of ventricular septal defect (VSD) in children. However, post-procedural hemolysis remains a clinically relevant complication, and its underlying mechanisms and risk factors have not been systematically investigated. Methods In this single-center retrospective cohort study, children who underwent transcatheter VSD closure at the Children's Hospital of Chongqing Medical University between June 2015 and June 2024 were included. Perioperative clin …

03.09.2026journal-article

Ege Tıp Dergisi

Clinical correlates of follow-up discontinuation in adult psychiatric outpatients: A retrospective cohort study

Deniz Alçı, Sevda Yıldız Saray

Aim: This study aimed to compare treatment continuation and follow-up discontinuation in adult psychiatric outpatients and to evaluate the clinical variables associated with discontinuation.Materials and Methods: In this retrospective, single-center, observational study, patients aged 18 years and older who were evaluated and started on treatment at the Psychiatry Outpatient Clinic of Balıkesir University Faculty of Medicine Hospital between January 1, 2024 and December 31, 2024 were reviewed. One hundred patients …