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European Health Evidence

The European alternative to PubMed

EUVIMED is the European alternative to PubMed: a central, multilingual research platform for medicine, nursing, life sciences and healthcare. It brings together international and European literature sources, study registries, open-access full texts, citations and retraction notices in one search. Unlike pure bibliographic databases, EUVIMED supports the entire research process – from discovery and appraisal with LIVIA and CLARA to traceable evidence synthesis. European in focus, transparent, interoperable and designed for science and healthcare.

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EUVIMED Themenbrowser · Medizin · Seite 153

Was ist neu im Gesundheitswesen?

Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
07.09.2026journal-article

Sinusitis

Hyperbaric Oxygen Therapy in Sinonasal Disease: A Narrative Review of Mechanisms, Clinical Evidence, and Multidisciplinary Perspectives on Invasive Fungal Rhinosinusitis and Post-Radiotherapy Injury

Daniele Salvatore Paternò, Luigi La Via, Antonino Maniaci, Mario Lentini, Adriana Cordalonga, Caterina Maria Testa, Francesco Piccitto, Enrico Provinzano, Paolo Tummino, Emilia Concetta Lo Giudice, Massimiliano Sorbello

Background: Hyperbaric oxygen therapy (HBOT) is proposed as an adjunct in two sinonasal conditions of high morbidity: acute invasive fungal rhinosinusitis (AIFRS) and post-radiotherapy injury. Methods: We conducted a narrative review and reported it against SANRA; PubMed/MEDLINE was searched (1980–2026; 1414 records screened, 589 retained), with Cochrane, society guidance and reference screening. Results: No randomised trial has tested HBOT against sinonasal endpoints in either indication. In AIFRS the dedicated ev …

07.09.2026journal-article

Journal of Clinical Laboratory Analysis

MicroRNA ‐Mediated Autophagy and Cardiovascular Diseases: Exploring the Crossroads of Atherosclerosis and Beyond

Sepehr Ebrahimi‐Dehkordi, Amir Hossein Barjasteh, Aida Zarei, Sina Bazmi, Sarah Vaseghi, Sara Ashna, Amirreza Solati, Ali Yousefzadeh, Bita Safarzadeh Nasrabad, Zahra Mohammadi, Hamed Haddad Kashani, Mohammad Hossein Pourhanifeh

ABSTRACT Background Atherosclerosis (AS) is a complex cardiovascular disease characterized by the accumulation of lipids, inflammatory cells, and fibrous materials within arterial walls. Autophagy plays a critical role in maintaining cellular homeostasis and regulating lipid metabolism in vascular cells. MicroRNAs (miRNAs), small non‐coding RNA molecules involved in post‐transcriptional gene regulation, have emerged as key modulators of autophagy and contributors to AS progression. Methods This review synthesizes c …

07.09.2026journal-article

Thrombosis and Haemostasis

Clinical Characteristics and Early Outcomes of Acute Pulmonary Embolism Presenting with Syncope

Marina López-Rubio, Victor Manuel Martínez-Castilla, Andrea Cobo-Bustamante, Lorena Sanz-Tejeiro, Rubén Alonso-Beato, Lucía Ordieres-Ortega, Crhistian-Mario Oblitas, Luis Antonio Álvarez-Sala Walther, Francisco Galeano-Valle, Pablo Demelo-Rodriguez

Abstract The prognostic significance of syncope in patients with acute pulmonary embolism (PE) remains uncertain. We assessed its association with early outcomes and explored whether distinct clinical phenotypes could be identified within this group. We analyzed a prospectively collected single-center cohort of patients with confirmed symptomatic PE diagnosed between 2010 and 2025, grouped by syncope at presentation. The primary outcome was a 30-day composite of all-cause mortality, major bleeding, and recurrent ve …

07.09.2026journal-article

The Clinical Journal of Pain

Pain Trajectories and Influencing Factors After Total Joint Arthroplasty

Xinru Liu, Xindie Zhou, Zhenzhen Du, Jiapei Yao, Shijie Jiang, Liangliang Wang, Zijuan Wu, Jingjing Shang

Objectives: This study aims to explore postoperative pain trajectories in patients undergoing total joint arthroplasty (TJA) and to identify patterns of pain change and their influencing factors. Methods: We used convenience sampling to select 374 patients with total joint arthroplasty at a Grade A tertiary hospital. Among them, 304 completed perioperative pain assessments from before surgery to postoperative day 90. Latent class growth model (LCGM) was used to distinguish subgroups of pain trajectories, and multiv …

07.09.2026journal-article

Frontiers in Microbiology

Analysis of gut microbiota and fecal/plasma short-chain fatty acids in non-dialysis renal anemia patients: associations with clinical parameters

Lin Yang, Lifen Liu, Pingping Kong, Wenwen Xu, Zhiyuan Wang, Siqi He, Jing Lou, Yanna Dou

Renal anemia is one of the most common complications of chronic kidney disease (CKD). This study investigated gut microbiota composition and fecal/plasma short-chain fatty acids (SCFAs) in 30 non-dialysis renal anemia patients and 20 healthy controls. Gut microbiota was assessed by 16S rRNA gene amplification sequencing and SCFAs were measured using gas chromatography-tandem mass spectrometry (GC–MS/MS). Compared with healthy controls, renal anemia patients showed distinct gut microbiota composition, including high …

07.09.2026journal-article

BMC Emergency Medicine

Development and internal validation of a simple EMS-based clinical score for predicting 24-hour mortality among older adult trauma patients: a retrospective single-centre cohort study

Thongpitak Huabbangyang, Pramote Papukdee, Adisak Nithimathachoke

Abstract Background Early prediction of short-term mortality among older adult trauma patients in prehospital settings remains challenging. This study aimed to develop and internally validate a simple emergency medical services (EMS)-based clinical score for predicting 24-hour mortality among older adult trauma patients using routinely available prehospital variables. Methods This retrospective, registry-based, single-center cohort study included 665 trauma patients aged ≥ 60 years who were transported by EMS to a …

07.09.2026journal-article

Transfusion

First molecularly characterized Para‐Bombay phenotype in Iraq: Clinical, serological and genetic insights with implications for transfusion safety

Dhargam Muhamed Aljebouri, Mohammed Aljadiri, Bassam Alshaikhli, Rawa Alattabi, Arwa Alkhamess, Sajjad Aldoori, Yousif Suleiman

Abstract Background H‐deficient states are important in ABO‐related transfusion practice. Patients may be misclassified as group O if testing stops at forward ABO typing. Anti‐IH may render group O units incompatible and increase hemolysis risk. Study Design and Methods A 70‐year‐old Iraqi man was referred for failure to obtain compatible blood before knee arthroplasty. ABO testing, crossmatching, antibody screening, anti‐H lectin testing, saliva inhibition and molecular analysis of fucosyltransferase 1 (FUT1) and …

07.09.2026journal-article

V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY

Clinical diagnosis of PTSD and the severity of comorbid symptoms in military personnel with combat experience

M. L. Baranov, Yu. A. Chaika

Background . In military personnel with combat experience, posttraumatic symptoms frequently co-occur with anxiety, depressive symptoms, and anger-related manifestations, making it difficult to distinguish PTSD from other stress-related disorders when relying solely on screening instruments. Clinical verification is therefore essential not only for evaluating the diagnostic utility of self-report measures, but also for clarifying the structure of comorbid emotional symptoms. Objective . To assess, in a clinically e …

07.09.2026journal-article

Journal of Behavioral Medicine

Maladaptive coping strategies mediate the relationship between perceived differential treatment and sleep health among women

Rupsha Singh, Symielle A. Gaston, Dale P. Sandler, Chandra L. Jackson

Abstract To investigate whether associations between perceived differential treatment based on race-ethnicity and sleep are mediated by coping strategies. We used data from the nationwide Sister Study. In 2008–2012, participants self-reported perceived lifetime differential treatment and completed adapted Coping Orientation to Problems Experienced Inventory (COPE)/Brief COPE questionnaires which assessed healthy/adaptive (e.g., using emotional support) and maladaptive (e.g., self-blame) coping. Sleep duration, poor …

07.09.2026journal-article

Journal of Hospital Medicine

Early clinical and laboratory indicators for differentiating infectious from autoimmune encephalitis in pediatric patients: A single‐center retrospective cohort study

Ruth Vela Sosa, Audrey Uong, Alvaro Coronado‐Muñoz

Abstract Background Pediatric encephalitis is associated with significant morbidity. Early recognition of autoimmune encephalitis (AE) is critical for timely immunotherapy and improved outcomes. Objectives To externally validate a previously published adult encephalitis prediction model in a pediatric cohort and identify predictors of pediatric AE. Methods This retrospective single‐center study included children 90 days to 21 years with encephalitis between January 2016 and September 2025. Clinical and laboratory d …

07.09.2026journal-article

Russian Journal of Transplantology and Artificial Organs

Kidney transplant program at the Chelyabinsk Regional Clinical Hospital

D. A. Altman, A. E. Poltorak, L. Yu. Zhuravleva, I. Ya. Bondarevsky, A. V. Gogolevskaya, B. H. Sarsenbaev, M. A. Poltorak, A. G. Istomin, A. S. Ryzhikh, P. A. Zasypkina

Objective: to evaluate the outcomes of kidney transplants performed at Chelyabinsk Regional Clinical Hospital between 2015 and 2025. Materials and methods . A retrospective analysis was conducted of 148 medical records of patients who underwent a kidney transplant (KT). The parameters assessed were recipient age and sex, duration of hemodialysis prior to transplantation, underlying cause of end-stage chronic kidney disease, duration of surgery and hospitalization, cold ischemia time, graft function, occurrence of a …

07.09.2026journal-article

Journal of Cardiovascular Development and Disease

Catheter-Based Renal Denervation in Uncontrolled and Resistant Hypertension: Evidence, Guidelines, Special Populations and Clinical Implementation

Ioannis Skalidis, Leonidas Koliastasis, Panayotis K. Vlachakis, Anastasios Apostolos, Maria Bozika, Kassiani-Maria Nastouli, Nicolas Amabile, Philippe Garot, Thomas Hovasse, Mariama Akodad, Livio D’Angelo, Antoinette Neylon, Thierry Unterseeh, Roswitha Schreier, Giacomo Maria Cioffi, Julius Jelisejevas, Peter Wenaweser, Pascal Meier, Mario Togni, Stephane Cook

Hypertension remains the leading modifiable cause of cardiovascular death, yet fewer than one in four treated adults achieves guideline-recommended blood pressure targets. Catheter-based renal denervation interrupts efferent and afferent renal sympathetic signalling and lowers blood pressure continuously and independently of medication adherence. After a decade of controversy following the neutral SYMPLICITY HTN-3 trial, a coherent body of second-generation sham-controlled randomised evidence, generated with radiof …

07.09.2026journal-article

Journal of Clinical Psychopharmacology

The Antidepressant Effects of the mGlu2/3 Receptor Antagonist TS-161 in Treatment-Resistant Depression

Mark D. Kvarta, Mai Watanabe, Satoshi Ozaki, Dede Greenstein, Adam Fijtman, Gregory Jones, Hiroe I. Hu, Solaleh Azimipour, Peixiong Yuan, Jenessa N. Johnston, Jennifer W. Evans, Jessica R. Gilbert, Carlos A. Zarate

Background: Like ketamine, group II metabotropic glutamate receptor (mGluR2/3) antagonists increase glutamate release and monoaminergic signaling, promote synaptic plasticity, and show antidepressant-related activity in preclinical models. A recent phase I trial of the orthosteric mGluR2/3 antagonist prodrug TS-161 established its safety, tolerability, and pharmacokinetic profile. Methods: This phase IIa randomized, placebo-controlled, double-blind, crossover, proof-of-concept, single-site trial was designed to eva …

07.09.2026journal-article

Epileptic Disorders

Functional (dissociative) seizures in PCDH19 ‐clustering epilepsy: Clinical characteristics and diagnostic challenges

Rita Cagigal, Javier Peña‐Ceballos, Patrick B. Moloney, Elena González‐Alguacil, Nuria Lamagrande, Ethan Tennant, Maria Jesus Martínez‐González, Victor Gomez‐Mayordomo, Andrea Garcia‐Ortega, Radu‐Ștefan Perjoc, Oana‐Aurelia Vladâcenco, Kette Valente, Rhys H. Thomas, Victor Soto‐Insuga, Norman Delanty, Rikke S. Møller, Ángel Aledo‐Serrano

Abstract Objective Functional (dissociative) seizures (FDS) are increasingly recognized among individuals with epilepsy, intellectual disability (ID), and psychiatric disorders, but their occurrence in PCDH19‐clustering epilepsy (CE) has not been systematically described. We aimed to characterize the clinical features, diagnostic pathways, and management of FDS in individuals with genetically confirmed PCDH19‐CE. Methods We conducted a multicenter retrospective study across six tertiary European Epilepsy Centers. I …

07.09.2026journal-article

Journal of Occupational & Environmental Medicine

Beyond Ergonomics Training: Added Effects of a Supervised, Equipment-Free Workplace Exercise Program on Musculoskeletal Symptoms, Sleep, and Burnout in Artisanal Pastry Workers: A Randomized Controlled Trial

Ömer ŞEVGİN, Amin DANESHFAR

Objective: To determine whether adding a supervised exercise program to workplace ergonomics education adds benefit for musculoskeletal, sleep, and burnout outcomes in börek (Turkish pastry) workers. Methods: In this exploratory randomized controlled trial (NCT07447180), 60 male börek masters from 47 Istanbul shops were randomized to ergonomics education alone or education plus a 12-week supervised, equipment-free exercise program. The primary outcome was the number of symptomatic body regions (Nordic Musculoskelet …

07.09.2026journal-article

Sensors

A Review of Fault Diagnosis and Intelligent Operations and Maintenance for Agricultural Machinery: Fault Mechanisms, Key Technologies, and Practical Recommendations

Yu Zhang, Xingzhu Qian, Ruifan Tang, Chenyu Xi, Tingrui Cui, Zhong Tang

Agricultural machinery operates under variable loads, impacts, dust, and changing soil–crop interactions, allowing faults to propagate through energy, material, information, and control pathways. This qualitative review synthesizes 195 research publications across fault formation, trustworthy diagnosis, prognostics and proactive risk control, maintenance and recovery, and case-based evidence assessment. Empirical findings are reported separately from review-derived recommendations, the authors’ conceptual requireme …

07.09.2026journal-article

Journal of Clinical Gastroenterology

Global Action in Addressing the Challenge of Environmental Change and Digestive Health

Anahita Sadeghi, Paria Boustani, Rui Morais, Desmond Leddin

Background: Environmental change is adversely affecting digestive health. Paradoxically, digestive health care contributes to the problem by generating emissions and waste. This study aimed to develop a set of metrics, a report card, to assess the response of the global digestive health community to this challenge. Methods: A survey was developed covering 26 actions that digestive health societies could take to reduce the environmental impact of digestive care. It was distributed to the leadership of national diges …

07.09.2026journal-article

Clinical Nuclear Medicine

Multiple Bone Metastases Exhibiting Exceptionally High 18F-MFBG Uptake Exceeding Physiological Bladder Activity in a Patient With Neuroblastoma

Mingyu Zhang, Jie Feng, Keyu Zhang, Xiaoya Wang, Jigang Yang

In neuroblastoma, 18 F-MFBG uptake in metastatic lesions is typically lower than physiological urinary bladder activity. We present a case of a 6-year-old boy with high-risk neuroblastoma who underwent multimodal therapy. A follow-up 18 F-MFBG PET/CT performed for treatment response assessment demonstrated markedly increased tracer accumulation in multiple skeletal metastases, with an SUVmax of 77.1, surpassing concurrent bladder activity. This case demonstrates that osseous metastases in patients with neuroblastom …

07.09.2026journal-article

Nano Research

CRISPR-Cas9 cleaves DNA microspheres to release drug for efficient thrombosis treatment

Shuai Yang, Ningning Wang, Yihang Huang, Xingang Wang, Qianyun Tang, Guoqing Tang, Jianggui Shan, Peifeng Liu

Abstract The drug delivery nanocarriers are widely employed in thrombolytic therapy. However, the off targeting and ineffective drug release of delivery vehicles make it difficult to targeted accumulation, effective diffusion, and penetration into thrombus tissue. Herein, we reported a biocompatible magnetic microsphere constructed via a programmable DNA rolling circle amplification (RCA) reaction integrated with iron oxide magnetic nanoparticles (Fe3O4 NPs). By combining ultrasound and photoacoustic imaging for di …

07.09.2026journal-article

Asian Journal of Pharmaceutical and Clinical Research

ANALYTICAL QUALITY BY DESIGN-ASSISTED DEVELOPMENT AND VALIDATION OF A RAPID STABILITY-INDICATING GRADIENT ULTRA-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR SIMULTANEOUS ESTIMATION OF EMPAGLIFLOZIN, SACUBITRIL, AND VALSARTAN IN PHARMACEUTICAL DOSAGE FORMS

BADRI SIREESHA, SARAVANAN RAVINDRAN

Objectives: Simultaneous estimation of empagliflozin, sacubitril, and valsartan in combined pharmaceutical formulations is analytically challenging due to their differing polarity, physicochemical properties, and chromatographic retention behavior. Conventional high-performance liquid chromatography methods often require longer analysis times and greater solvent consumption. To develop, optimize, and validate a rapid, robust, and stability-indicating gradient ultra-performance liquid chromatography (UPLC) method fo …

07.09.2026journal-article

Journal of Pediatric Orthopaedics

Publication Volume and Fellowship Characteristics Are Associated With Future Academic Faculty Appointments in Pediatric Orthopaedic Surgery

Jason Silvestre, Prudhvi Kodali, Pooya Hosseinzadeh, Wudbhav N. Sankar, John M. Flynn

Background: Factors associated with future academic faculty appointments after pediatric orthopaedic surgery fellowship training remain unknown. This study determines fellow and training program factors associated with future academic faculty appointments in pediatric orthopaedic surgery. Methods: This was a case-control study of pediatric orthopaedic surgery fellows from 2017 to 2023. Cases consisted of academic faculty, and controls were in a nonacademic practice setting. Demographic, bibliometric, and training v …

26.12.2026journal-article

Journal of Chemical Engineering Research Progress

Optimization Studies of The Treatment of Laundry Wastewater Using Activated Carbon Derived from HDPE Chars

David Emoefe Rockson-Itiveh, Cyril Oghenekome Anakpoha, Mabel Keke, Marcel Ajogri, Ulakpa Wisdom, Fabian Chidiebere Ozioko, Samson Onoriode Okpo

Growing plastic waste and industrial wastewater necessitate sustainable treatment solutions. This study optimized industrial wastewater treatment using activated carbon derived from high-density polyethylene (HDPE) pyrolysis char via thermal activation, eliminating the need for aggressive chemical agents. Characterization via FTIR, BET, and SEM-EDX revealed a micro-mesoporous structure with a BET surface area of 287.3 m²/g, a 90.05 atomic percent carbon content, and dominant pore sizes of 2.1 to 2.6 nm. The adsorbe …

07.09.2026journal-article

Russian Journal of Transplantology and Artificial Organs

Principles Of developing predictive models in medicine and Their application in liver transplantation

A. R. Monakhov

Prognostic models have become an integral part of clinical practice in liver transplantation (LT), supporting decision-making throughout the patient’s clinical pathway – from assessment of the severity of underlying disease to postoperative monitoring of graft function. This review aims to systematize the principles of development, validation, and quality assessment of clinical prognostic models, with a particular focus on the scales used in LT. The review is based on an analysis of key publications on the methodol …