Alle Themen: neue Gesundheitspublikationen – Seite 145

05.09.2026journal-article

BMC Oral Health

Clinical consequences, treatment status, and parental awareness of traumatic dental injuries among high school students: a cross-sectional study in Cairo

Maha A. Elhousiny, Nada A. Salem, Mervat I. Fawzy, Mai M. Mahmoud

Abstract Background This study assessed the current clinical consequences and treatment status of previous traumatic dental injuries (TDIs) affecting permanent anterior teeth among adolescents aged 15–17 years in Cairo, Egypt, and evaluated parental awareness and knowledge regarding the emergency management of TDI. Subjects and methods A school-based analytical cross-sectional study assessing treatment history was conducted among 2,000 secondary school students aged 15–17 years using multistage stratified sampling. …

05.09.2026journal-article

International Journal of Advances in Medicine

Real-world evidence study evaluating the effectiveness, tolerability and utilization patterns of Vonoprazan in routine clinical practice across out-patient clinical setting in India

Arka Banerjee, Tanvi Shetty, Kushal Sarda, Akhilesh Sharma

Background: Gastroesophageal reflux disease (GERD) and peptic ulcer disease (PUD) are two of the most common acid-related gastrointestinal conditions in India. They are associated with significant morbidity and impaired quality of life. Vonoprazan has demonstrated clinical efficacy in clinical trials and offers rapid and sustained acid suppression. However, there is still a dearth of empirical data on its therapeutic application and efficacy in Indian patients. Methods: This multicentre, retrospective, observationa …

05.09.2026journal-article

Journal of Orthopaedic Surgery and Research

Exploratory evaluation of large language models in patient-oriented orthopedic MRI report interpretation: a two-stage study

Quan Zhang, Chen Zhang, Jie Zhang, Liping Li, Huyu Du

Abstract Background Magnetic resonance imaging (MRI) reports for orthopedic conditions are filled with highly specialized terminology, leading to information asymmetry between clinicians and patients. Deficiencies persist in routine patient education regarding orthopedic imaging results, and a well-documented mismatch exists between physicians’ professional explanations and patients’ actual understanding of medical information. Objective This study aimed to explore the feasibility of utilizing large language models …

05.09.2026journal-article

BMC Oral Health

Familial clustering of clinically measured oral health in co-resident three-generation families: a family-linkage study using KNHANES data

Seon-Jip Kim, Hyun-Jae Cho

Abstract Background Oral diseases cluster in families and follow a strong social gradient, yet how far this familial patterning extends across generations, and whether it reflects shared socioeconomic position, is poorly understood. Most evidence is limited to parents and children and to self-reported oral health. Using clinically measured periodontitis and caries experience, we examined whether clinically measured oral health is concordant between successive generations within co-resident three-generation families …

05.09.2026journal-article

Lasers in Medical Science

Antimicrobial photodynamic therapy mediated by phenothiazine photosensitizers against Candida albicans and Candida auris: a systematic review

Giovanna Fontgalland-Ferreira, Sarah Marinho Figueiredo, Karla Nogueira Matos, Vinicius Leão Roncolato, Claudio Teruo Kassa, Maria Vitória Pigozzi-Portugal, Ilka Tiemy Kato, Renato Araujo Prates

Abstract Fungal infections caused by Candida albicans and Candida auris represent an increasing clinical challenge, particularly due to biofilm formation and rising antifungal resistance. Antimicrobial photodynamic therapy (aPDT) has emerged as a potential alternative strategy, with phenothiazine-based photosensitizers being among the most extensively investigated compounds. This systematic review aimed to evaluate the application of phenothiazine-mediated aPDT in in vitro studies against C. albicans and C. auris . …

05.09.2026journal-article

Asian Journal of Education and Social Studies

Chinese-English Translation of Museum Public Signs within the Comprehension-Expression-Adaptation Framework: A Qualitative Case Study

Yan Huang, Yuebin Li

Museum public signs mediate historical and cultural information for linguistically diverse audiences, and their translation requires both source-text accuracy and target-language accessibility. This qualitative case study applies Li Changshuan’s Comprehension-Expression-Adaptation (CEA) framework to nine Chinese-English bilingual exhibition-text pairs from the Nanning Museum of Urban Construction. The corpus comprises 43 photographs of bilingual signs collected during an on-site visit. Of the corresponding English …

05.09.2026journal-article

AGING MEDICINE

Insights Into the Mechanisms of Biological Aging That Guide Translational and Clinical Research

Evandro Fei Fang, Hilde Nilsen, Morten Scheibye‐Knudsen, Vilhelm A. Bohr, Lin Kang

ABSTRACT Understanding the molecular mechanisms of aging guides the development of prevention, intervention, and treatment strategies to reduce the incidence of common age‐associated diseases. Over the past decades, the proposed key features (hallmarks) of aging cells have directly or indirectly provided us clues, furthering our understanding of the causes of disease and assisting with the development of therapeutic strategies for diseases such as rare premature aging diseases like Werner syndrome and ataxia telang …

05.09.2026journal-article

Journal of Clinical Medicine

Phenotype-Specific Pharmacogenetic Patterns of Methotrexate Neurotoxicity in Pediatric Acute Lymphoblastic Leukemia

Javier Gómez-Román, Juan C. Restrepo, Luz M. González, Laura González-Rodríguez, Ángela Lacombe-Antoneli, Yolanda Gutiérrez-Martín, María Dolores de la Maya, Montserrat Mesegué, José Luis Dapena, Ana Carbone, Berta González Martínez, Francisco Lendínez Molinos, Antonio Molinés Honrubia, Miriam Abós García, Marina García Morín, Samuel Navarro Noguera, María Sagaseta de Ilurdoz, Itziar Astigarraga, Maria Baro Fernández, Jaime Verdú Amorós, Alexandra Regueiro, Manuel Ramírez Orellana, José Luis Fuster Soler, Soledad González Muñiz, Adela Cañete Nieto, Montserrat Torrent Español, Héctor González Méndez, Jose M. Vagace, Guillermo Gervasini

Background: Methotrexate-induced neurotoxicity (MTX-NTX) is a severe complication during childhood acute lymphoblastic leukemia (ALL) treatment, yet its underlying pharmacogenetic determinants remain incompletely understood. Methods: A multicenter retrospective nationwide case–control study was performed including 71 pediatric ALL patients (34 MTX-NTX cases and 37 controls). Targeted next-generation sequencing of 17 genes involved in MTX transport, intracellular metabolism and folate pathways was performed. Results …

05.09.2026journal-article

Discover Public Health

Determinants of socioeconomic status and community well-being among vulnerable groups in post-conflict Tigray, Ethiopia

Tesfay Gebreigziabher Emnetu, Alemseged Gerezgiher Hailu, Kinfe Abraha Gebre-Egziabher

Abstract This study examines the determinants of socioeconomic status (SES) and their implications for the well-being of structurally vulnerable groups in post-conflict Tigray, Ethiopia, following the 2020–2022 armed conflict. Grounded in a multidimensional SES framework encompassing occupation, livelihood, health, and education, the study adopts a cross-sectional explanatory mixed-methods design. Quantitative data were collected from 590 respondents using multistage sampling with proportional stratification across …

05.09.2026journal-article

Editon Consortium Journal of Educational Management and Leadership

Influence of Teachers’ Attitude on the Use of Digital Devices in Kiswahili Content Delivery in Public Primary Schools in Kisumu East Sub-County, Kenya

Erastus Onditi Otieno, Sharon Onditi, Berther Kute

This study examined the relationship between teachers’ attitude towards digital devices and Kiswahili content delivery in public primary schools in Kisumu East Sub-County, Kisumu County, Kenya. The study adopted a mixed-methods descriptive survey design. Data were collected from Teachers of Kiswahili and Heads of Institutions using questionnaires and interviews and analysed using descriptive statistics, Pearson correlation and regression analysis. The findings showed that teachers generally had a favourable attitud …

05.09.2026journal-article

International Journal of Innovation and Technology Management

Forecast Emerging AI-Enabled Healthcare Systems with the Text Mining Framework Based on Lingo Algorithm

Peng Wei Wang, Yi Jie Wang, Wei Chong Choo, Keng Yap Ng, Ran Bi

This study establishes an integrated text mining framework to forecast developmental trends and structural mismatches in artificial intelligence (AI)-enabled healthcare diagnostic systems by jointly analyzing scientific literature and patent data from 2018 to 2022. We employ the LINGO clustering algorithm combined with singular value decomposition (SVD), TF–IDF weighting, and expert evaluation to identify technological themes, map lifecycle stages, and construct a systematic technology roadmap. Results reveal that …

05.09.2026journal-article

Clinical and Experimental Medicine

Cell-based therapies of autoimmune diseases in the context of artificial intelligence development

Diya Dinesh, Snigdha Suman Das, Barshana Bhattacharya, K. Sreedhara Ranganath Pai

Abstract Autoimmune diseases are comprised of several chronic inflammatory conditions characterized by activation of autoreactive T and B lymphocytes and produces autoantibodies. While most of the current treatment options mainly rely on non-specific immunosuppression, stem cell based therapies can be a promising candidate for promoting “immune reset” and restore long term tolerance against these complex diseases. Stem cell based therapy eliminate autoreactive clones and reconstitute immune tolerance. Besides, mese …

05.09.2026journal-article

University Management: Practice and Analysis

University Campus Health-Preserving Environment: Medical Infrastructure and Health Risk Analysis

N. L. Antonova, A. V. Kulminskaia, A. A. Tronina

The article on the materials of the sociological study presents an analysis of the health risks of students living in an autonomous (suburban) university campus with a medical institution on its territory. The new trajectory of the development of Russian universities includes the creation of new autonomous campuses, including those located in the suburban area. Modern campuses serve the development of human capital and act as a point of attraction for young people, teachers, scientists, strengthening their competit …

05.09.2026journal-article

University Management: Practice and Analysis

The Interconnection of Physical and Psychological Health Care Practices Among Studentsf

S. Yu. Sharypova, S. S. Gordeeva

This article presents a detailed analysis of practices for caring for physical and psychological health among students. The study aims to describe individual practices and to identify how they combine with each other, forming stable behavioral patterns among students at Russian universities. The empirical base consists of data from a paperbased questionnaire survey of students from three Russian universities (n = 415), conducted in 2024. Frequency and correlation analyses, odds ratio calculations, and cluster analy …

05.09.2026journal-article

University Management: Practice and Analysis

University Health Preserving Ecosystem: Digital Tools and Artificial Intelligence Technologies in Management

M. A. Chervonnyy, A. P. Glukhov, N. N. Abakumova, E. S. Sinogina

The article systematizes digital tools and artificial intelligence (AI) technologies as key elements of healthpreserving management in a modern university. The aim of the study is not only to summarize existing technological solutions, but also to develop practical managerial approaches to their implementation, integration and performance evaluation within a unified healthpreserving ecosystem. The methodology includes an analysis of scientific publications, industry reports and implementation cases for 20202025, as …

05.09.2026journal-article

Brazilian Journal of Implantology and Health Sciences

BROQUIOLITE INFANTIL E ASSISTÊNCIA EM EMERGÊNCIA RESPIRATÓRIA

Maria Eduarda Bezerra do Nascimento, Ana Beatriz Oliveira de Melo, João Pedro Barbosa Souza Marques, Bruna de Sousa Loiola, Ana Laura Prigol, Jamille Constante Monteiro, Caio Daniel Monteiro Martins, Victor Eduardo da Silva Mendes, Karolyne Alvarez Bispo, Aríssia Vaz Rodrigues da Silva, Jéssica Alessandra Pereira, Yasmin Maria Silveira Faleiros Ferreira Pimenta, Gabriela Aparecida Rigato, Stefânia Araújo Pereira

A bronquiolite infantil constitui uma das principais infecções do trato respiratório inferior em lactentes e crianças menores de dois anos, apresentando elevada frequência nos serviços de urgência e emergência pediátrica. Este estudo teve como objetivo analisar os principais aspectos relacionados à bronquiolite infantil, com ênfase nos fatores de risco, sinais de gravidade e assistência prestada em situações de emergência respiratória. Trata-se de uma revisão integrativa da literatura, de abordagem qualitativa e ca …

05.09.2026journal-article

International Journal of Clinical Pharmacy

Knowledge, attitudes and practices among Australian community pharmacists towards naloxone and overdose prevention: a national cross-sectional study

Louisa Picco, Monica Jung, Rose Laing, Jeffrey Bratberg, Beth Sproule, Suzanne Nielsen

Abstract Introduction Naloxone is an opioid overdose reversal drug that is available for free without a prescription via participating community pharmacies in Australia. Aim To investigate Australian community pharmacists’ knowledge, attitudes, practices, and provision of naloxone and overdose prevention, and identify barriers to and correlates of naloxone provision. Method Data were collected between January and April 2025 via an anonymous, cross-sectional questionnaire among Australian community pharmacists who w …

05.09.2026journal-article

World Journal of Experimental Biosciences

Carbapenem Resistance is Associated with Biofilm formation in Clinical isolates of Klebsiella pneumoniae

Sura Jabuk, Mehdi Meskini Heydarlou, Muhammad Shawal, Ata Ur Rehman

Carbapenem-resistant Klebsiella pneumoniae (CRKP) and biofilm-producing nosocomial pathogenic bacteria may complicate treatment and infection control. The relationship between carbapenem resistance and biofilm formation remains poorly characterized. Susceptibility to imipenem, doripenem, ertapenem, amikacin, and levofloxacin was assessed using the Kirby-Bauer disk diffusion assay and CLSI M100 breakpoints for ninety-five non-duplicate clinical isolates of K. pneumoniae. The crystal-violet microtiter assay, which me …

05.09.2026journal-article

Biomedicines

Insulin Tolerance Test in Adult GH Deficiency: An Exploratory Study Deriving BMI-Dependent Cut-Offs Using a Clinical Reference Standard

Daniela Cuboni, Francesca Mocellini, Michela Sibilla, Giada De Lauro, Emanuele Varaldo, Alessandro Maria Berton, Nunzia Prencipe, Ezio Ghigo, Silvia Grottoli, Mauro Maccario, Valentina Gasco

Background: The diagnosis of adult growth hormone (GH) deficiency (GHD) relies on demonstrating a reduced GH response to stimulation tests. Excess body weight, an increasingly prevalent condition, is associated with a blunted GH response to all types of stimulation tests. Therefore, establishing body mass index (BMI)-dependent cut-offs is essential for accurate interpretation. This study aimed to identify BMI-specific diagnostic thresholds for the insulin tolerance test (ITT), using residual pituitary function as t …

05.09.2026journal-article

Online Brazilian Journal of Nursing

Saúde para praticantes do Omolokô: estrutura representacional, espiritualidade e cuidado

Carla Cristina Gonçalves, França Helena Elias Pereira, Lívia Fajim de Melo, Milena Quaresma Lopes, Priscila Cristina da Silva Thiengo de Andrade, Antonio Marcos Tosoli Gomes

Objective: To describe the structure of social representations of health for Omolokô practitioners, as constructed by its followers. Method: A descriptive study with a qualitative approach, supported by the Central Nucleus Theory (CNT) of social representations, conducted across 05 Omolokô terreiros located in the State of Rio de Janeiro, with 106 participants. Results: The results show that health, for this group, is represented by four intersecting dimensions: spiritual, attitudinal, affective, and biomedical. Co …

05.09.2026journal-article

Journal of Advances in Medical and Pharmaceutical Sciences

Self-Medication with Analgesics among Community Pharmacy Clients in Yenagoa, Nigeria: Patterns, Demographic Correlates and Public Health Implications

Timi Fiekumo Buseri, Ibegi, Ibegi Saviour, Success Tamunoibi Gwembe, Keme Kelvin Yenagoa, Buseri, Oyintokoni Beauty

Background: Self-medication is a global public health practice conventionally dominated by analgesics, antipyretics and antimicrobials, yet the demographic structure of this behaviour and its association with information sources remain poorly characterised in Nigerian community pharmacy settings. Objective: To determine the prevalence, patterns and demographic correlates of self-medication among community pharmacy clients in Yenagoa Local Government Area (LGA), Bayelsa State, Nigeria, with particular attention to a …

05.09.2026journal-article

Health Affairs Scholar

The Vendorification of Medicare Advantage

David J Meyers, Jeffrey Marr

Abstract Medicare Advantage (MA) plans increasingly outsource core functions to third-party vendors, a trend termed the "vendorification" of MA. Vendors now play major roles in star-rating maximization, risk-code capture, and prior authorization, with evidence that vendor-conducted prior authorization yields higher denial rates and more appeal reversals than reviews conducted internally by insurers. This commentary examines three potential challenges that may be posed by vendorification: increased federal spending …

05.09.2026journal-article

Italian Journal of Anatomy and Embryology

Beyond overload: A biofeedback-based assessment linking postural awareness and sensorimotor control to musculoskeletal health in orchestral musicians

Giuditta Carretti, Tommaso Lastrucci, Mirko Manetti, Mirca Marini

Professional musicians often develop playing-related musculoskeletal disorders (PRMDs) from prolonged static postures, repetitive movements, and chronic biomechanical overload. However, the link between instrumental practice, postural awareness, and sensorimotor control lacks objective, multidimensional investigation. This preliminary study explored these relationships in 28 professional orchestral musicians divided into wind, bowed, and string instrument groups. Participants completed a structured questionnaire in …

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Aktuelle Forschung nach Fachgebiet

Clinical consequences, treatment status, and parental awareness of traumatic dental injuries among high school students: a cross-sectional study in Cairo

Real-world evidence study evaluating the effectiveness, tolerability and utilization patterns of Vonoprazan in routine clinical practice across out-patient clinical setting in India

Exploratory evaluation of large language models in patient-oriented orthopedic MRI report interpretation: a two-stage study

Familial clustering of clinically measured oral health in co-resident three-generation families: a family-linkage study using KNHANES data

Antimicrobial photodynamic therapy mediated by phenothiazine photosensitizers against Candida albicans and Candida auris: a systematic review

Chinese-English Translation of Museum Public Signs within the Comprehension-Expression-Adaptation Framework: A Qualitative Case Study

Insights Into the Mechanisms of Biological Aging That Guide Translational and Clinical Research

Phenotype-Specific Pharmacogenetic Patterns of Methotrexate Neurotoxicity in Pediatric Acute Lymphoblastic Leukemia

Determinants of socioeconomic status and community well-being among vulnerable groups in post-conflict Tigray, Ethiopia

Influence of Teachers’ Attitude on the Use of Digital Devices in Kiswahili Content Delivery in Public Primary Schools in Kisumu East Sub-County, Kenya

Forecast Emerging AI-Enabled Healthcare Systems with the Text Mining Framework Based on Lingo Algorithm

Cell-based therapies of autoimmune diseases in the context of artificial intelligence development

University Campus Health-Preserving Environment: Medical Infrastructure and Health Risk Analysis

The Interconnection of Physical and Psychological Health Care Practices Among Studentsf

University Health Preserving Ecosystem: Digital Tools and Artificial Intelligence Technologies in Management

BROQUIOLITE INFANTIL E ASSISTÊNCIA EM EMERGÊNCIA RESPIRATÓRIA

Knowledge, attitudes and practices among Australian community pharmacists towards naloxone and overdose prevention: a national cross-sectional study

Carbapenem Resistance is Associated with Biofilm formation in Clinical isolates of Klebsiella pneumoniae

Insulin Tolerance Test in Adult GH Deficiency: An Exploratory Study Deriving BMI-Dependent Cut-Offs Using a Clinical Reference Standard

Saúde para praticantes do Omolokô: estrutura representacional, espiritualidade e cuidado

Self-Medication with Analgesics among Community Pharmacy Clients in Yenagoa, Nigeria: Patterns, Demographic Correlates and Public Health Implications

The Vendorification of Medicare Advantage

Beyond overload: A biofeedback-based assessment linking postural awareness and sensorimotor control to musculoskeletal health in orchestral musicians