Ophthalmic Surgery, Lasers and Imaging Retina
Effect of Hormone Replacement Therapy on Risk of Age-related Macular Degeneration Among an Aggregate Health Record Cohort
Background and Objective: Estrogen in hormone replacement therapy (HRT) exerts anti-inflammatory effects believed to oppose age-related macular degeneration (AMD) pathogenesis, but whether HRT can be protective against AMD is contested. The aim of the study was to evaluate the association between HRT use and the risk of development and progression of AMD in postmenopausal women. Patients and Methods: This was a retrospective cohort study utilizing ICD-10 codes for HRT usage and rates of AMD development and progress …