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European Health Evidence

The European alternative to PubMed

EUVIMED is the European alternative to PubMed: a central, multilingual research platform for medicine, nursing, life sciences and healthcare. It brings together international and European literature sources, study registries, open-access full texts, citations and retraction notices in one search. Unlike pure bibliographic databases, EUVIMED supports the entire research process – from discovery and appraisal with LIVIA and CLARA to traceable evidence synthesis. European in focus, transparent, interoperable and designed for science and healthcare.

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EUVIMED Themenbrowser · Medizin · Seite 142

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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
04.09.2026journal-article

Journal of Cataract & Refractive Surgery

Photorefractive Keratectomy in Keratoconus: Long-Term Outcomes from a Pre-Cross-Linking Era Cohort

Gustavo E. Tamayo, Natalia Moros, Eduardo J. Polania-Baron, Claudia Castell, Pilar Vargas

Purpose: To describe long-term visual, refractive, and topographic outcomes after photorefractive keratectomy (PRK) in keratoconus patients treated before corneal cross-linking (CXL) became available. Setting: Single private ophthalmic center in Bogotá, Colombia. Design: Retrospective observational study. Methods: 1,532 archived paper charts from all patients at the practice between 1996 and 2004 were screened. Patients with keratoconus who underwent PRK using multiple excimer laser techniques, with adequate preope …

04.09.2026journal-article

The Indonesian Journal of General Medicine

PENATALAKSANAAN KOMPREHENSIF MASALAH KESEHATAN INDIVIDU DAN KELUARGA PADA REMISI DIABETES MELITUS TIPE 2 MELALUI MODIFIKASI GAYA HIDUP (DIET, LATIHAN FISIK, DAN DUKUNGAN KELUARGA): SEBUAH EVIDENCE-BASED CASE REPORT

Michael Aquilar Sugianto

Pendahuluan: Diabetes melitus (DM) tipe 2 secara tradisional dianggap sebagai penyakit kronik progresif ireversibel. Paradigma ini berubah sejak konsensus ADA/EASD/Diabetes UK/Endocrine Society 2021 mendefinisikan remisi DM tipe 2 sebagai HbA1c 3,6 juta partisipan). DiRECT: remisi 46% vs 4% pada bulan ke-12 (OR 19,7; IK95% 7,8–49,8) dan 36% vs 3% pada bulan ke-24 (aOR 25,82; IK95% 8,25–80,84). DIADEM-I: remisi 61% vs 12% (OR 12,03; IK95% 5,17–28,03). Terdapat hubungan dosis-respons penurunan berat badan dengan remi …

04.09.2026journal-article

Journal of Abdominal Wall Surgery

Contemporary global practice in dissection and closure techniques for lower abdominal transverse incisions: a cross-sectional survey

Leo R. Brown, Hephzibah Adegoke, Ellen Gardner, Thomas M. Drake, James Lucocq, Artur Zanellato

Purpose To characterise international contemporary practice in dissection and closure of lower abdominal transverse incisions (LATI) across surgical specialties. Methods An open, cross-sectional survey of surgeons with experience of performing LATI independently was conducted using an anonymised online questionnaire disseminated via professional networks. Data were captured pertaining to respondent characteristics, operative techniques for dissection and closure of abdominal layers, and experience with incisional h …

04.09.2026journal-article

European Journal of Nuclear Medicine and Molecular Imaging

PSMA PET/CT-guided salvage elective nodal radiotherapy for nodal metastases after radical prostatectomy: a bi-institutional long-term outcome analysis

Samuel M. Vorbach, Thomas Seppi, Giulia Santo, Irene Virgolini, Ute Ganswindt, Michael Keilholz, Sarah Frederike Brose, Jozefina Casuscelli, Konrad Klimek, Rudolf A. Werner, Nina-Sophie Schmidt-Hegemann, Claus Belka, Christian Trapp, Paul Rogowski

Abstract Purpose PSMA PET/CT has transformed the detection of nodal recurrence after radical prostatectomy, yet real-world evidence on long-term outcomes of PSMA PET/CT-guided salvage elective nodal radiotherapy (ENRT) remains limited. This study evaluated oncological outcomes of PSMA PET/CT-guided salvage ENRT in a bi-institutional cohort with extended follow-up. Methods We retrospectively analysed 179 patients who received PSMA PET/CT-based ENRT for nodal recurrence after radical prostatectomy at two tertiary cen …

04.09.2026journal-article

Smart Medicine

Herbal Formula AC591 Protects Against Cisplatin‐Induced Hearing Loss by Inhibiting p53‐Mediated Ferroptosis

Yunhao Wu, Yu Tao, Lin Wei, Qiuping Liu, Jiaxin Liu, Wen Jiang, Weiwei Shi, Peng Cao, Xiaolong Fu, Cheng Cheng

ABSTRACT Cisplatin is a widely utilized chemotherapeutic agent for the treatment of malignant cancers. However, its clinical application is significantly restricted due to its severe ototoxicity. Therefore, identifying protective medications to prevent cisplatin‐induced hearing loss (CIHL) is of paramount importance. Here, we show that AC591, derived from the classical herbal formula “Huangqi Guizhi Wuwu decoction,” exhibits notable protective effects on cisplatin‐induced ototoxicity. Our findings indicate that pre …

04.09.2026journal-article

Frontiers in Medicine

Out-of-pocket expenditure on medicine for chronic patients and its economic impact on Indian households: a systematic review and meta-analysis

Deepak Kumar Vaishnav, A. Venkat Raman, Akriti Bansal, Pradeep Nair, Krishna Kharwar

Background Out-of-pocket expenditure (OOPE) on medicines constitutes a substantial component of healthcare spending in India, particularly among patients with chronic diseases requiring continuous treatment. This systematic review and meta-analysis aimed to synthesise evidence on medicine-related OOPE in India and assess its magnitude and variation across disease categories, healthcare settings, and provider sectors. Methods We conducted a systematic review and meta-analysis in accordance with PRISMA 2020 guideline …

04.09.2026journal-article

Frontiers in Psychiatry

Correlation between treatment-related symptom burden and psychological flexibility in patients with cervical cancer and their combined correlational association with emotional distress

Jiao Ma, Yan Peng, Qin Chen, Xinying He, Haixiang Wang

Objective To explore the correlation between treatment-related symptom burden and psychological flexibility in patients with cervical cancer, as well as the combined correlational association of these two factors with patients’ emotional distress, so as to provide a theoretical basis for formulating targeted psychological intervention strategies in clinical practice. Methods A cross-sectional survey was conducted. A total of 216 patients with cervical cancer who received treatment in our hospital from June 2025 to …

04.09.2026journal-article

Frontiers in Medicine

Short-term postoperative neurocognitive safety and recovery profiles of remimazolam tosilate combined with flumazenil vs. propofol in cirrhotic patients undergoing endoscopic variceal treatment: a randomized controlled trial

Yanjie Chen, Xiangrong Du, Fu Shi, Na Zhu

Background Patients with liver cirrhosis frequently exhibit compromised drug metabolism due to hepatic dysfunction, which significantly increases their susceptibility to postoperative neurological adverse events. This study aimed to evaluate the impact of remimazolam tosilate combined with flumazenil on early postoperative neurocognitive function and recovery quality in cirrhotic patients undergoing endoscopic variceal ligation (EVL) and/or endoscopic variceal sclerotherapy (EVS), so as to provide evidence-based gu …

04.09.2026journal-article

Medicine

Generic nutritional risk index and urinary incontinence in U.S. older adults

Juan Xu, Shangqi Cao, Xu Hu, Xiang Li, Shu Wen

This study aims to evaluate the association between the geriatric nutritional risk index (GNRI) and urinary incontinence (UI). This cross-sectional study utilized data derived from 9 cycles (2001–2018) of the National Health and Nutrition Examination Survey. Weighted multivariable logistic regression models were employed to assess the connection between GNRI and UI [stress UI (SUI), urgency UI (UUI), and mixed UI (MUI)]. Smooth curve fitting was conducted to explore the linear association between GNRI and UI. Subgr …

04.09.2026journal-article

Medicine

Does adding ultrasound-guided subacromial injection improve clinical outcomes after suprascapular nerve block in chronic subacromial impingement syndrome?

Gülçin Gazioğlu Türkyilmaz, Mesut Bakir

Ultrasound-guided suprascapular nerve block (SSNB) and subacromial injection (SI) are commonly used for chronic subacromial impingement syndrome (SIS), but the additional benefit of combining these interventions remains uncertain. This study evaluated whether adding ultrasound-guided SI to SSNB improves clinical outcomes in patients with chronic MRI-confirmed SIS who had failed conservative treatment. This retrospective cohort study included consecutive patients with chronic SIS treated between December 2021 and Ja …

04.09.2026journal-article

Medicine

Efficacy and safety of laparoscopic-guided transversus abdominis plane block versus port-site local anesthetic infiltration in laparoscopic cholecystectomy

Javeria Javed, Mahnoor Qasim, Zaryab Bacha, Hunain Shahbaz, Noman Rajput, Fatima Sajjad, Munazza Sikhandar, Ogechukwu Obi, Khushal Khan, Pukar Adhikari, Bilal Aslam, Muhammad Usman Haider, Muhammad Hammad Sharif

Background: Postoperative pain following laparoscopic cholecystectomy remains a major clinical concern, and the optimal method of local anesthetic delivery is unresolved. This systematic review and meta-analysis evaluated the efficacy and safety of laparoscopic-guided transversus abdominis plane (LTAP) block versus port-site local anesthetic infiltration for reducing pain, opioid use, and improving recovery in patients undergoing LC. Methods: This review was conducted per Preferred Reporting Items for Systematic Re …

04.09.2026journal-article

Medicine

MRI susceptibility-related artifacts following prolonged use of silver-containing dressings

Bo Liu, Jiahao Wang, Jinning Jiang, Tianchang Wang, Jingwu Zhang, Xiufei Liu, Weicai Xue

Rationale: Silver-containing dressings are widely used in postoperative and chronic wound care because of their antimicrobial properties. Although these dressings are generally considered compatible with magnetic resonance imaging (MRI) under standard conditions, prolonged use in chronic open wounds may be associated with local retention or deposition of silver-containing material. This could contribute to susceptibility-related signal loss or distortion on MRI and interfere with the evaluation of underlying anatom …

04.09.2026journal-article

Medicine

Immunomodulatory roles of the HLA family and B2M in atherosclerosis

Ke Ma, Jingping Ge

Atherosclerosis (AS), a chronic inflammatory disease driven by lipid accumulation and immune dysregulation, predisposes to acute cardiovascular events via plaque rupture and thrombosis. The molecular mechanisms linking immune microenvironment imbalance to plaque instability remain incompletely defined. Utilizing the GSE100927 dataset (69 AS patients vs 35 controls), we identified differentially expressed genes (DEGs) and constructed co-expression networks via weighted gene co-expression network analysis. Hub genes …

04.09.2026journal-article

Frontiers in Medicine

An update on the diagnosis and treatment of seborrheic keratosis

Sri Nauli Dewi Lubis, Imam Budi Putra

Background Seborrheic keratosis (SK) is a common benign epidermal neoplasm, particularly affecting the elderly. Although non-malignant, it often poses cosmetic and diagnostic challenges due to its resemblance to malignant skin tumors. This review aims to provide a comprehensive update on the recent advancements in the epidemiology, pathogenesis, diagnostic modalities, and therapeutic approaches for SK. Methods A narrative review of current literature was conducted, focusing on molecular insights, diagnostic innovat …

04.09.2026journal-article

Frontiers in Cell and Developmental Biology

Progress on hydrogel delivery systems targeting metabolism disorders in the treatment of diabetic foot ulcers

Shihua Liu, Lixian Huang, Hong Dong

Diabetic foot ulcer (DFU) is a severe and difficult-to-heal complication of diabetes in which systemic metabolic dysregulation is translated into local neurovascular injury and dysfunction of wound-healing cells. This narrative review examines the relationships among glucose, lipid, and amino acid/protein metabolism disorders, the dysfunction of macrophages, fibroblasts, and endothelial cells, and hydrogel-based therapeutic strategies. Persistent hyperglycemia disrupts the tricarboxylic acid cycle, activates the po …

04.09.2026journal-article

ANZ Journal of Surgery

How to Do 10 mL Syringe Port Retroperitoneal Access for Staged Minimally Invasive Pancreatic Necrosectomy

Katharine Ji, Adrian Fox, Matthew Marshall‐Webb

ABSTRACT Acute necrotising pancreatitis with infected pancreatic necrosis has a significant mortality of up to 23.5%, with survival dependent on achieving a complete necrosectomy. In recent years, several minimally invasive techniques have been developed including laparoscopic and endoscopic approaches, which are feasible, well‐tolerated and beneficial for the patient when compared with open surgery. Percutaneous drainage with radiologically guided drains has limited efficacy as pancreatic necrosis is mostly solid …

04.09.2026journal-article

Frontiers in Endocrinology

Synergistic effect of insulin resistance and glycemic variability on mortality in ICU patients with gastrointestinal bleeding: impact of the TyG-GVI index and development of an explainable web-based clinical calculator

Yanqiu Jiang, Keyang Guo, Kexin Jiang, Shengshan Xu, Ke-Jie He

Objective To investigate the association between the composite Triglyceride-Glucose Index combined with Glycemic Variability (TyG-GVI) and early-death risk in ICU patients with gastrointestinal bleeding, and evaluate whether integrating this biomarker into ensemble-learning models improves prognostic performance. Methods This retrospective study analyzed adult ICU patients (≥18 years) with gastrointestinal hemorrhage as the principal diagnosis from the MIMIC-IV v3.1 database. TyG-GVI was calculated as the product o …

04.09.2026journal-article

Oncologie

PFB-03 study protocol: diagnostic performance and clinical application of 18 F-FAPI-PET/CT for detecting axillary metastasis in breast cancer patients after neoadjuvant therapy

Ru Yao, Yang Qu, Zhixin Hao, Jiahui Zhang, Jie Lian, Aocheng Wu, Songjie Shen, Feng Mao, Bo Pan, Qiang Sun, Li Huo, Yidong Zhou

Abstract Objectives Axillary lymph node (ALN) status is a crucial prognostic factor in breast cancer. Accurate, non-invasive methods for evaluating axillary lymph node metastasis after neoadjuvant therapy (NAT) are needed to optimize surgical decisions and minimize patient morbidity. Fibroblast activation protein inhibitor (FAPI) PET/CT targets cancer-associated fibroblasts and may improve diagnostic accuracy. This study aims to assess the diagnostic performance and clinical utility of 18 F-FAPI PET/CT in detecting …

04.09.2026journal-article

Hormone and Metabolic Research

Recent Advances in Glucagon-Like Peptide-1 Receptor and Melanocortin-4 Receptor Agonists for the Treatment of Obesity and Type 2 Diabetes

Chang-Min Lee, Jin-Young Kim, Jeong-Hyun Shim, Gwang-won Cho

Abstract The global rise in aging populations has been accompanied by increasing rates of obesity and type 2 diabetes, both of which pose significant public health and economic challenges. This review aims to investigate the pathophysiological link between obesity and diabetes and evaluate emerging therapeutic strategies that involve glucagon-like peptide-1 receptor and melanocortin-4 receptor agonists, including their dual and triple agonist developments. A comprehensive literature review was conducted focusing on …

04.09.2026journal-article

JEADV Clinical Practice

Dietary Patterns in Patients With Hidradenitis Suppurativa

Maria Victoria Gerdes‐Miranda, Marianne Bengtson Løvendorf, Simon Francis Thomsen, Lone Skov, Charlotte Näslund‐Koch

ABSTRACT Background Hidradenitis suppurativa (HS) is a chronic immune‐mediated inflammatory skin disease associated with obesity and metabolic syndrome. However, the role of diet is still unexplored. Objectives The aim of this study was to describe dietary habits in patients with HS and to examine the association between an unhealthy diet and disease severity. Methods In this cross‐sectional study we included patients with HS from out‐patient clinics of two different departments of dermatology. Patients were enroll …

04.09.2026journal-article

Frontiers in Medicine

From hematuria warning to precision immunotherapy: an AI-assisted cross-platform analysis of bladder cancer information on social media

Peng Han, Xin Yang, Qiuxiang Li, Pengcheng Lu, Penghuan Wang, Zhonglei Deng, Zeping Gui, Yiping Zong, Mingyu Liu

Objective Bladder cancer often presents with hematuria, while modern management increasingly depends on pathology-based risk stratification, immunotherapy, and biomarker-informed treatment. This study evaluated whether social media videos adequately connect early hematuria warning with precision bladder cancer care. Methods We conducted a cross-sectional, AI-assisted structured extraction and urologist consensus-scored content analysis of publicly available videos from Bilibili, Douyin, and YouTube. Videos were sea …

04.09.2026journal-article

Innovative Medicine of Kuban

Stress Levels in Anesthesiologists and Intensivists: A Prospective Multicenter Observational Study

V. E. Ironosov, K. V. Pshenisnov, Yu. S. Aleksandrovich, V. Yu. Talaiko, V. S. Potapov, A. V. Soboleva, F. G. Ulmasov

Anesthesiology and intensive care medicine is one of the medical specialties in which professional practice is associated with frequent stress and the development of burnout syndrome. Objective : To assess the level of stress in anesthesiologists and intensivist according to the characteristics of their professional practice and length of clinical experience. Materials and methods : An anonymous survey was conducted among 138 anesthesiologists and intensivists, including 79 (57.2%) women and 59 (42.8%) men. The que …

04.09.2026journal-article

Innovative Medicine of Kuban

Surgical Treatment of Atrophic Femoral Shaft Nonunion

D. A. Zelyanin, V. E. Dubrov, L. V. Abramenkova, M. L. Mukhanov

This review aims to identify the advantages and limitations of the treatment strategies for atrophic femoral nonunion and is based on the analysis of 358 publications (from 1973 to 2025). The literature search was conducted using the PubMed (MEDLINE) and eLibrary databases in accordance with the PRISMA guidelines for systematic reviews. The analysis demonstrated that the majority of the publications consist of single case reports or small case series. No universally accepted standard for the treatment for this cond …

04.09.2026journal-article

Complex Issues of Cardiovascular Diseases

BIOMATERIALS IN AORTIC ROOT SURGERY: MID-TERM OUTCOMES

Roman N. Komarov, Maxim I. Tkachev, Elizaveta A. Palaznik, Nikoloz I. Kviloriya, Armais A. Galstyan, Daniil V. Rodin, Maria V. Pipnik, Grayr G. Shabunts, Diana O. Mdivnishvili, Margarita P. Zaikina

Highlights For the first time, a comparative study was conducted of the medium‑term results of using aortic homografts, autografts (Ross operation), and a domestic biological conduit in the surgical treatment of aortic root pathology. It has been shown that all three biomaterials provide high survival rates, acceptable freedom from reoperations, and stable hemodynamics in the medium term. The data obtained indicate the clinical viability of the domestic biological conduit as a competitive alternative to traditional …