JAMA Pediatrics
Trends in Preclinical and Clinical Obesity Among Adolescents
This study examines trends in preclinical and clinical obesity among US adolescents.
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JAMA Pediatrics
This study examines trends in preclinical and clinical obesity among US adolescents.
Psychopharmacology and Addiction Biology
This article summarizes the outcomes of three symposia on psychopharmacology held within the framework of the XIII All-Russian Conference with International Participation “Current Issues in Preclinical and Clinical Research of Medicinal Products and Clinical Trials of Medical Devices” (St. Petersburg, April 23–24, 2026). The advancement of modern psychopharmacology requires the implementation of personalized approaches, the application of molecular modeling and computational biology methods, and the integration of …
Journal of Imaging Informatics in Medicine
Abstract Artificial intelligence (AI) is increasingly introduced into radiological practice to support image interpretation, workflow optimization, and diagnostic decision-making. However, successful clinical adoption depends not only on technical performance but also on radiologists’ trust in these systems. This study investigates radiologists’ perceptions of AI in clinical practice and examines how these perceptions relate to trust in AI-assisted diagnostic decision-making. We conducted a cross-sectional online s …
Brazilian Journal of Health Aromatherapy and Essential Oil
The traditional drug discovery and development process is historically characterized by high attrition rates, escalating financial costs, and decade-long timelines. The emergence of artificial intelligence (AI) and machine learning (ML) has transformed this paradigm by enabling efficient navigation through vast chemical spaces and the integration of complex multi-omic datasets. This evidence-based literature review critically examines the evolution and application of computational technologies across the pharmaceut …
Journal of Online Trust and Safety
The concepts of ‘intersectionality’ and ‘marginalization’ are empirical necessities in Majority World trust and safety research because the harms that Majority World users face are constituted by multiple systems of power, not by any one axis alone. In this context, marginalization operates at three registers simultaneously: the marginalization of Majority World users by platform infrastructure that are not inherently designed to accommodate their needs; the marginalization of Majority World communities when existi …
Journal of Clinical Medicine
Background/Objectives: Cabazitaxel is an established treatment option for patients with metastatic castration-resistant prostate cancer (mCRPC), but outcomes beyond the conventional 10-cycle threshold remain incompletely characterized. This threshold largely reflects clinical trial design. We therefore evaluated outcomes associated with cabazitaxel treatment beyond 10 cycles using a predefined 8-month landmark analysis intended to reduce early immortal time bias. Methods: This retrospective single-center study incl …
Clinical Practice and Cases in Emergency Medicine
Case Presentation: A 26-year-old man with past medical history of prolactinoma presented two weeks status post endoscopic transsphenoid prolactinoma excision with a positional headache and cerebrospinal fluid rhinorrhea; he was found to have diffuse subarachnoid air. Discussion: There are few reports of subarachnoid pneumocephalus in the emergency medicine literature. Pneumocephalus, particularly tension pneumocephalus, typically occurs in the setting of traumatic skull fractures. However, emergency physicians shou …
International Journal of Pattern Recognition and Artificial Intelligence
Three-dimensional (3D) CT reconstruction from dual-view X-ray data is a severely ill-posed inverse problem, due to the substantial loss of structural information caused by the sparsity of the projection data. To address this challenge, we propose a dual-view X-ray-to-CT reconstruction framework based on vector quantized variational autoencoders (VQ-VAEs) and Transformer-based latent code translation. Specifically, a 3D VQ-VAE model is pre-trained to learn discrete latent representations of CT volumes, while a 2D VQ …
MRIMS Journal of Health Sciences
Abstract Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory syndrome that may mimic severe sepsis, resulting in delayed diagnosis. Bacterial infection-associated HLH is uncommon, particularly with Klebsiella pneumoniae . We report a case of a 38-year-old male presenting with community-acquired pneumonia, persistent fever, pancytopenia, hepatosplenomegaly, and marked hyperferritinemia. Bronchoalveolar lavage culture isolated K. pneumoniae , whereas bone marrow aspiration demonstrated he …
Brazilian Journal of Health Review
Introdução: A obesidade se tornou um dos maiores desafios globais de saúde e uma base importante para o desenvolvimento de doenças metabólicas, entre elas podemos destacar a doença hepática gordurosa não alcoólica. Objetivo: O objetivo do estudo foi analisar a relação entre DHGNA e síndrome metabólica em pacientes submetidos à cirurgia bariátrica metabólica. Métodos: Este estudo retrospectivo, descritivo e transversal, com abordagem quantitativa, foi conduzido no Rio Grande do Sul, Brasil. Os dados foram coletados …
Journal of Consumer Culture
This article challenges the dematerialization bias in digital intimacy studies and the sociological assumption that digital capitalism dissolves social bonds (alienation) by examining how Chinese female otome video game players materialize and embody their virtual relationships in their everyday life. While there is a rich literature on screen-based interactions, this study uses a multi-sited ethnography (2021–2024), including 106 participant interviews, to analyze the lived, material practices of post-digital inti …
Artificial Intelligence in Medical Imaging
Artificial intelligence (AI) is rapidly transforming clinical ophthalmology, with most validated applications in retinal and corneal imaging. In contrast, oculoplastic surgery – which encompasses eyelid, orbital, lacrimal, and periocular disorders – has only recently begun to incorporate AI into clinical workflows. Emerging applications include automated image analysis for eyelid malpositions, deep learning-based interpretation of orbital imaging, AI-assisted planning for dacryocystorhinostomy, and predictive model …
Frontiers in Human Dynamics
The frontline of healthcare is where formal policy becomes a human decision. Its defining feature has long been discretion, namely, situated judgment under scarcity, uncertainty, and unequal need. This Perspective argues that agentic artificial intelligence may do more than automate tasks or support professional judgment. When a system interprets cases, selects actions, and initiates later workflow activities, the discretionary act may move from the visible worker into a technical process. Drawing on street-level b …
Frontiers in Public Health
The social determinants of health (SDOH)—including socioeconomic position, education, housing, and social networks—are fundamental drivers of health inequalities worldwide. These inequalities persist because social determinants interact dynamically across time and context, with health emerging from the interplay of social, political, environmental, and biological processes in which determinants act simultaneously as causes and consequences. Early-life exposures and historical conditions produce enduring physiologic …
Clinical Nuclear Medicine
We report the case of a 58-year-old man with metastatic epithelioid sarcoma demonstrating an uncommon presentation of expanding tumor volume accompanied by a paradoxically lower SUV max on 18 F-FDG PET/CT. Conversely, 68 Ga-FAPI PET/CT demonstrated clear diagnostic superiority, exhibiting intense tracer avidity across established lesions and successfully uncovering multiple new, FDG-occult metastases. This distinct metabolic dissociation highlights a stromal-driven mechanism of tumor invasion. Ultimately, 68 Ga-FAP …
Journal of Food Science, Nutrition and Health
In recent years, aging and anti-aging have become a very common problem among some middle-aged people. Biologists have discovered that telomeres play a crucial part in our aging process because they can prevent genes on chromosomes from being lost. Moreover, some diseases are also associated with telomere length. Around 85% of malignant cells reactivate telomerase, enabling infinite cell division and continuous growth. Additionally, a variety of environmental factors, such as smoking and genetic factors, can influe …
Challenges
Planetary health has emerged as a critical framework for understanding the interdependence of human, social and ecological systems in the face of escalating global challenges. While discussions of planetary health have largely focused on policy and systems-level interventions, comparatively little attention has been given to the developmental foundations that shape how future generations will respond to these challenges, including climate change, biodiversity loss and widening social inequities. This viewpoint high …
Nature Immunology
Abstract Inflammation occurs during the recurring cycles of tissue degradation, repair and remodeling in the uterus, but the mechanisms by which the immune system contributes to uterine tissue integrity are unclear. We reveal that uterine monocytes have dual roles in both tissue remodeling and inflammation, depending on the reproductive cycle stage. Circulating inflammatory monocytes infiltrated the uterus before their differentiation into proinflammatory or pro-repair macrophages, depending on interferon-γ and tra …
Indian Journal of Animal Research
Background: Trauma to the spinal cord or vertebral column may result in permanent neurological dysfunction, including urinary incontinence, loss of spinal reflexes, paraplegia, paralysis and even death. Early presentation, accurate diagnosis and timely therapeutic intervention are critical factors influencing prognosis and functional recovery. Survey radiography and myelography remain important diagnostic tools for lesion localization and assessment of spinal cord compression. Depending on the severity and nature o …
Digital Social Sciences
The gap in access, skills, use, and benefits from digital technologies that were initially identified as “digital inequality” has grown into a “digital oppression” the systematic exclusion, exploitation, and control of existing marginalized groups by digital systems design, deployment, and governance. This paper draws on the most recent scholarship to synthesize the various components of the digital divide and how they intersect with race, gender, class, disability, and geography. It explores how digital technologi …
Journal of Business and African Economy
This study examined the blue economy, health sector outcomes on economic development in BRICS nations. The panel data were collected from world development indicator and Central bank of Nigeria respectively, covering 4 years span from 2021 to 2024 were used. The expost factor research design was used for this work. The study employed the econometric estimation of generalize method of moment model were used for the analysis, adopting panel data method of analysis. The estimated result shows a positive but statistica …
Frontiers in Psychology
Introduction In the current post-digital age, technology is omnipresent in our everyday lives and digital encounters with (even originally analog) art are increasingly pervasive. Museums, artists, and art professionals continue to utilize digital technologies in their practices, and both access to and awareness of digital platforms continue to expand. In spite of this, little is known about how experiences with digital reproductions on a computer actually compare to original artworks in a museum, especially regardi …
WORLD JOURNAL OF INNOVATION AND MODERN TECHNOLOGY
This is evidence that artificial intelligence (AI) has become a new paradigm in the area of electoral forecasting. As computational power and sets have grown exponentially, AI-powered models provide a more dynamic and data-intensive approach compared to conventional polling and statically methods. This review looks at the period from 2020 to 2025, based on a systematic search of major academic databases including IEEE Xplore, ACM Digital Library, ScienceDirect, PubMed and Google Scholar, which identified 63 studies …
Frontiers in Public Health
Human-animal interactions may impact the composition of the human microbiome. This can then influence human physical, mental, and social wellbeing. This scoping review synthesizes the literature on the impacts of intentional, non-occupational human-animal interactions on the human microbiome. Six databases (PubMed, CINAHL, PsycINFO, Web of Science, CAB Abstracts, and ProQuest Dissertations and Theses) were searched using keywords for human-animal interactions and microbiomes. Database searching resulted in 2,946 pu …