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European Health Evidence

The European alternative to PubMed

EUVIMED is the European alternative to PubMed: a central, multilingual research platform for medicine, nursing, life sciences and healthcare. It brings together international and European literature sources, study registries, open-access full texts, citations and retraction notices in one search. Unlike pure bibliographic databases, EUVIMED supports the entire research process – from discovery and appraisal with LIVIA and CLARA to traceable evidence synthesis. European in focus, transparent, interoperable and designed for science and healthcare.

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EUVIMED Themenbrowser · Medizin · Seite 141

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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
04.09.2026journal-article

The American Surgeon™

Proximity Is Not Access: Geographic Distance and Chemotherapy Receipt for Colon Cancer Requiring Surgery

Kathryn E. Ottaviano, Haoxuan Xu, Ashar Ata, Steven Wexner, Stephen P. Sharp

Background Access to health care facilities presents an obstacle to receiving appropriate cancer treatment. This retrospective cohort study analyzes how access to care by geographic distance and patient demographics affect receipt of chemotherapy in colon cancer patients requiring resection. Methods 342,779 patients with stages 2-4 colon cancer requiring surgery who were recommended to receive either neoadjuvant or adjuvant chemotherapy were analyzed using the NCDB from 2012 to 2021. Patients who refused chemothera …

04.09.2026journal-article

Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science

A digital twin-based approach for generalized fault diagnosis of high-speed train gearbox gears

Du Qinghua, Cui Wentao, Yang Xiaofei, Zheng Qing, Zhang Kai, Ding Guofu

Data-driven methods have been widely applied to fault diagnosis of high-speed train gearbox gears; however, their performance heavily depends on high-quality training data. Due to the inevitable degradation of gears during long-term service, significant distribution discrepancies arise between real-time operational data and historical data, which degrade the generalization capability and diagnostic accuracy of models. To address this issue, this paper proposes a digital twin-based generalized fault diagnosis method …

04.09.2026journal-article

Journal of Clinical Imaging Science

Clinical feasibility and image quality assessment of deep learning-based virtual contrast enhancement from photon-counting computed tomography

Julien G. Cohen, Joel Valentin Stadelmann, David Leite-Arada, Pierre-Alexandre Poletti

Objectives: The purpose of this study was to evaluate image quality and diagnostic performance of deep learning-based virtual contrast-enhanced (VCE) images generated from photon-counting CT (PCCT) datasets. Material and Methods: Forty consecutive patients who underwent contrast-enhanced PCCT were retrospectively included and divided into training ( n = 20) and testing ( n = 20) cohorts. A supervised U-Net-based convolutional neural network was trained to generate VCE images from virtual non-contrast inputs, using …

04.09.2026journal-article

Medicine

A systematic review and network meta-analysis of single nucleotide polymorphisms associated with oral submucous fibrosis risk

Chunxia Huang, Juan Liu, Bin Zeng, Lele Zhang, Zhihang Zhou, Xiaoshan Huang, Binsheng He, Meihua Bao

Background: Oral submucous fibrosis (OSF) is a chronic and insidious oral disease characterized by hyalinization of the subepithelial connective tissue and progressive fibrosis of the oral submucosa. It is a precancerous condition of oral squamous cell carcinoma. Studies have demonstrated that single nucleotide polymorphisms (SNPs) are closely associated with susceptibility to OSF. This study aims to comprehensively evaluate the association between SNPs and OSF risk and to rank the strength of the association betwe …

04.09.2026journal-article

Medicine

Potent bisphosphonate therapy for preventing fractures after denosumab discontinuation in osteoporosis

Asim Shah, Suleman Khan, Syeda Vilay Zehra Rizvi, Kanza Farhan, Misbah Uddin, Syeda Umme Abiha Rizvi, Sabika Fatima, Ang Raj Karan, Aizaz Anwar Khalid, Ahmad Ali, Somaiya Ahmed

Background: Denosumab cessation causes rebound bone turnover, fast bone loss, and an elevated risk of vertebral fractures. Pooled data about the fracture prevention efficacy of potent bisphosphonates (BPs) as sequential therapy have been lacking to counteract this risk. Methods: This systematic review and meta-analysis was carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines. PubMed, Scopus, the Cochrane Library, and ClinicalTrials.gov were searched from th …

04.09.2026journal-article

Medicine

The role of ferroptosis in juvenile idiopathic arthritis

Chun-Wu Yang, Xiu-Hua Pan, Ji-Gan Wang

This study employed a bidirectional 2-step, two-sample Mendelian randomization approach to investigate the causal relationships between ferroptosis-related genes and juvenile idiopathic arthritis (JIA) and to explore the mediating role of immune cells. Ferroptosis genes were identified from the deCODE database and matched with protein quantitative trait locus data as exposures to evaluate their causal effects on JIA, while immune cell traits were similarly assessed. For genes showing positive Mendelian randomizatio …

04.09.2026journal-article

Medicine

Electrolyte supplementation patterns and evaluation in perioperative parenteral nutrition for patients undergoing major thoracoabdominal surgery

Zhicheng Huang, Hua Jiang, Mingwei Zhu, Chun Gao, Zhenyi Jia, Wei Shen, He Huang, Wei Fan, Shiping Liu, Sheng Zhang, Lifu Zhu, Yang He, ZhiBing Hou, Linlin Fan, Caihong Hao, Jianghong Dai, Zijian Li, Ting Yuan, Lu Wang, Lianzhen Chen, Wei Chen

For patients undergoing major thoracoabdominal surgery, perioperative nutritional management is essential. Although enteral nutrition is preferred, parenteral nutrition (PN) is needed when oral or enteral intake is inadequate or contraindicated and serves as a key electrolyte source. Electrolytes are crucial for fluid balance, acid–base stability, and metabolic function, and inappropriate supplementation may cause serious disturbances. Real-world evidence on perioperative PN electrolyte use in China remains limited …

04.09.2026journal-article

Medicine

Relationship between cirrhosis patients’ social support and post-traumatic stress symptoms

Jintao Cheng, Huiqiong Gui, Suyun Guo, Yihua Yang, Yun Ran

Patients with cirrhosis frequently exhibit post-traumatic stress symptoms (PTSS), which may further aggravate serious psychological and psychiatric conditions. However, the underlying mediating mechanisms by which social support affects PTSS remain insufficiently elucidated. From November 2024 to July 2025, patients with cirrhosis were recruited via cluster sampling from a tertiary hospital in Shenzhen, Guangdong Province, China. A total of 380 participants completed the Perceived Social Support Scale, the civilian …

04.09.2026journal-article

Medicine

Incidental noninvasive diagnosis of isolated persistent left superior vena cava in asymptomatic adults

Dian Zhang, Meifang Pan

Rationale: Isolated persistent left superior vena cava (IPLSVC) is an extremely rare congenital malformation with a low overall prevalence in the general population. Most patients present without typical clinical manifestations, leading to a relatively high rate of missed diagnoses in clinical practice. Owing to abnormal venous drainage, IPLSVC is frequently complicated with lesions of the cardiac conduction system, which may further induce arrhythmias. Patient concerns: A 37-year-old asymptomatic male patient acci …

04.09.2026journal-article

Medicine

Causal associations of gastroesophageal reflux disease with sepsis and sepsis mortality within 28 days

Yangyang Tong, Jie Liu

Previous studies have demonstrated a potential correlation between gastroesophageal reflux disease (GERD) and sepsis. However, the causal association between GERD and sepsis remains unclear. We performed a bidirectional 2-sample Mendelian randomization (MR) analysis to investigate the causal associations of GERD with sepsis and sepsis mortality within 28 days. The inverse variance weighted method was used as a major method for the MR study, supplemented with multiple approaches, including MR-Egger, weighted median, …

04.09.2026journal-article

JAMA Network Open

Cognitive Behavioral Therapy vs Media Literacy for Prevention of Gaming Disorder and Unspecified Internet Use Disorder

Katajun Lindenberg, Sonja Kewitz, Ina Neumann, Sebastian Brand, Daniel Huth, Julia Lardinoix, Katharina Leo, Carolin Szász-Janocha, Daniel L. King, Lutz Wartberg

Importance Mitigating the harmful effects of digitalization on youth mental health is essential. Objectives To evaluate the effectiveness of cognitive behavioral therapy (CBT) compared with a media literacy–based intervention for gaming disorder and unspecified internet use disorder and to determine whether universal or indicated prevention yields stronger benefits. Design, Setting, and Participants PROTECTconfirm was a randomized clinical trial conducted from July 1, 2020, to August 31, 2024, across 44 secondary s …

04.09.2026journal-article

Applied Sciences

A Unified and Interpretable Benchmark of Classification Models for DGA-Based Power Transformer Fault Diagnosis

Kıvanç Doğan, Merve Ertarğın, Abuzer Çalışkan, Ayşenur Bakay

Power transformers are among the most critical components of electric power transmission and distribution systems, and unexpected failures can lead to substantial economic losses and prolonged power outages. Dissolved Gas Analysis (DGA) is the most widely used diagnostic technique for transformer fault diagnosis and involves interpreting gases dissolved in insulating oil. However, conventional interpretation methods, such as the Rogers ratio, the Doernenburg ratio, the IEC 60599 ratio method, and the Duval Triangle …

04.09.2026journal-article

International Journal of Innovative Technologies in Social Science

NITROUS OXIDE IN MEDICINE - ENHANCING PATIENT COMFORT AND HEALTH: A NARRATIVE REVIEW

Natalia Borek, Emilia Miśkiewicz, Julia Gałązka, Ewa Stopa, Hanna Krupa, Magdalena Kędrak, Zofia Wieczorek, Dominik Stanisławski, Wiktoria Jabłońska-Trzosek, Jakub Pochwalski

Introduction: Nitrous oxide (N2O) is a colorless inhalational agent widely used in medicine due to its analgesic, anxiolytic, and sedative properties. Owing to its effectiveness and safety, it has become an important tool for improving patient comfort during various medical and dental procedures. Aim: The aim of this narrative review was to summarize current evidence regarding the pharmacological properties, clinical applications and safety profile of nitrous oxide. Material and methods: A narrative review of the l …

04.09.2026journal-article

International Journal of Molecular Sciences

Multi-Target Antitumor Effects of Natural Products and Approved Drug Repurposing in Non-Small Cell Lung Cancer: Advances in Mechanisms, Combination Regimens, Delivery System Optimization, and Clinical Challenges

Yuli Xie, Dashuai Zhang, Pei Tang

Non-small cell lung cancer is one of the leading causes of cancer-related mortality. The effectiveness of treatment is limited by several factors, including significant tumoral heterogeneity, rapid development of drug resistance, high metastatic potential, and a complex tumor microenvironment. In recent years, natural products have emerged as valuable resources for the discovery of novel antitumor strategies against non-small cell lung cancer. These compounds possess diverse chemical properties, target multiple pat …

04.09.2026journal-article

Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi

Primary Anastomosis After Emergency Small-Bowel Resection: Safety, Outcomes, and the Role of Hypoalbuminemia in a 270-Patient Cohort

Muhammed Salih Süer, Serkan Demir, Ahsen Kalender, Lara Kavasoğlu, Şener Balas

Aim: Emergency small bowel resections are complex procedures performed under life-threatening conditions such as ischemia, perforation, or trauma. The decision between primary anastomosis and fecal diversion is critical, with anastomotic leakage posing a significant risk to patient outcomes. This study aims to evaluate the safety and feasibility of primary anastomosis in emergency small bowel resections and to identify potential predictors of leakage.Material and Methods: This retrospective cohort study was conduct …

04.09.2026journal-article

Formosan Journal of Surgery

Malignant Transformation of a Solitary Fibrous Tumor with Intracranial Invasion and Distant Metastasis: A Case Report

Wei-Shun Chiu, Yun-Kai Chan, Shiu-Jau Chen, Cheng-Chia Tsai, Chih-Chuan Yang, Hsin-Yao Lin

Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms that are commonly benign but may occasionally exhibit a malignant behavior. Herein, we describe a 57-year-old male patient with a previously benign SFT originating from the left zygomatic scalp that subsequently underwent malignant transformation with invasion into the left temporal lobe and metastases to the right 5 th rib and left femur. Although the patient underwent multiple surgical resections and received adjuvant radiotherapy and systemic chemothe …

04.09.2026journal-article

Frontiers in Cardiovascular Medicine

Exploring the role of ascending aortic length to prevent type A acute aortic dissection

Alberto Pozzoli, Livia Waltert, Mirko Muretti, Laura Anna Leo, Marta Sannito, N'Guessan Kra, Tiziano Torre, Enrico Ferrari, Susanna Grego, Stefanos Demertzis

Background Stanford type A acute aortic dissection (AAD) often occurs before the given threshold for prophylactic surgery. This study investigates the role of the ascending aortic length (AAL) integrated to aortic height index (AHI) as an additional factor in the risk stratification of AAD. Thereby, the relationship between AAL and the aortic diameter, as well as the patient's height, will be evaluated. Methods Patients undergoing surgery for AAD at our Institution between January 2013 and February 2024 were prospe …

04.09.2026journal-article

Frontiers in Medicine

Case Report: Autoimmune hepatitis following oxaliplatin exposure presenting with multifactorial non-cirrhotic portal hypertension and recurrent parastomal variceal bleeding

Wei Cheng, Hongbo Shi, Jiaju Fan, Xiaoming He, Haibin Shi, Yi Li, Yunfeng Huan, Shengqin Zhang

Ectopic variceal hemorrhage accounts for approximately 5% of all variceal bleeding episodes and represents an uncommon manifestation of portal hypertension. This report describes recurrent parastomal variceal bleeding in a 43-year-old woman with rectal adenocarcinoma who underwent abdominoperineal resection followed by five cycles of oxaliplatin-containing chemotherapy. During chemotherapy, severe hepatocellular injury developed. A liver biopsy performed in June 2020 demonstrated severe interface hepatitis with lym …

04.09.2026journal-article

Frontiers in Medicine

Adjunctive traditional Chinese medicine for ischemic stroke: a systematic review with structured narrative synthesis and GRADE assessment of randomized controlled trials

Ting Liu, Mingjing Lu, Ying Wang, Hailing Ding, Xiangqian Kong

Ischemic stroke is a leading cause of death and long-term disability, and traditional Chinese medicine (TCM) is widely used alongside conventional care in East Asia. We reviewed randomized controlled trials (RCTs) of adjunctive TCM in ischemic stroke, analyzing the evidence by clinical phase and by individual formulation rather than as a single treatment class. We searched seven bibliographic databases and one clinical trial registry to 8 April 2026, for trials of adults with imaging-confirmed ischemic stroke given …

04.09.2026journal-article

Complementary Medicine Research

Datura metel in Homoeopathy: Novel therapeutic insights from an open-label multicentre clinical verification study

Panaparambil Azis Suhana, Meenu Gupta, Jain Vij Shruti, Charu Sehgal, Kaushal Kumar Savera, Prasanta Kumar Pradhan, Amit Srivastava, Punam Kumari, Vibha Kumari, Kumar Keshav Avinash, Ratan Chandra Shil, Sunil S. Ramteke, Divya Verma, Uttam Singh, Partha Sarathi Chakraborty, Binit Dwivedi, Beenu Saini, Ann Maria Rose, Dibyajyoti Mohapatra, Renu Verma, Meera Sharma, Subhash Kaushik

Background: Clinical Verification in Homoeopathy is a systematic scientific procedure that confirms the therapeutic utility of homoeopathic medicines. Despite its referencing in homoeopathic literature, Datura metel remains fragmentarily verified and rarely prescribed. To address this gap, the Central Council for Research in Homoeopathy (CCRH) conducted clinical verification of the medicine to assess its clinical utility and expand its therapeutic potential. Methods: A multicentric open-label single-arm study was c …

04.09.2026journal-article

Acta Epileptologica

A decade later: a longitudinal retrospective cohort study of the clinical course of childhood-onset epilepsy in a multi-ethnic tertiary centre

Jen Ern Tan, Juen Kiem Tan, Michelle Maryanne Tan, Zhi Xuan Ng, Zhee Yee Chan, Zi Qi Ang, Nur Arifah Mohd Khaili, Nur Liyana Rahmat, Jasmine Lee, Ching Soong Khoo, Hui Jan Tan, Sau Wei Wong

Abstract Background Epilepsy affects a significant proportion of people globally, with many cases beginning in childhood. However, there is a lack of longitudinal studies exploring the long-term outcomes and characteristics of childhood-onset epilepsy into adulthood. This study aimed to analyze the trajectory of childhood-onset epilepsy to identify particular characteristics and outcomes that could help guide future management. Methods This retrospective cohort study was conducted between June 2021 and December 202 …

04.09.2026journal-article

Journal of modern medicine

DIAMINE OXIDASE DEFICIENCY AND HISTAMINE INTOLERANCE: CURRENT APPROACHES TO DIAGNOSIS AND DAOPRIM THERAPY

I.S. Razikova, D.K. Pozilov

This review summarizes current evidence regarding the clinical and pathogenetic aspects of diamine oxidase (DAO) deficiency, histamine intolerance, contemporary diagnostic approaches, and pathogenetic treatment strate­gies. Histamine intolerance is characterized by impaired degradation of histamine due to reduced DAO activity, leading to the accumulation of histamine and the development of gastrointestinal, dermatological, neurological, res­piratory, and cardiovascular manifestations that often mimic IgE-mediated a …

04.09.2026journal-article

Russian Bulletin of Otorhinolaryngology

Tonsillitis-associated arthropathies: new approaches to diagnosis and treatment

A.I. Kryukov, A.A. Klimenko, A.S. Tovmasyan, S.R. Ramazanov

Objective. To identify and develop criteria for the tonsillogenic nature of reactive arthropathies in patients with chronic tonsillitis (CT). Material and methods. This prospective cohort study enrolled 150 patients with CT aged 18 to 35 years. The main group (Group I, n=75) consisted of patients with CT and arthralgia, the control group (Group II, n=75) included patients with CT without joint syndrome. All patients underwent questioning, clinical and laboratory examination (including CRP, ASL-O, RF, ACCP, ANA on H …

04.09.2026journal-article

Russian Bulletin of Otorhinolaryngology

Modern possibilities for the diagnosis of voice disorders using computer acoustic analysis of voice and artificial intelligence

A.I. Kryukov, S.G. Romanenko, O.G. Pavlikhin, D.I. Kurbanova, E.V. Lesogorova, O.V. Eliseev, Kh.Z. Khaybulaev, E.N. Krasilnikova, T.K. Polyaeva

Objective. The purpose of the review is to analyze modern approaches to the diagnosis of voice disorders using AI and acoustic analysis, as well as to evaluate their effectiveness and prospects for implementation in clinical practice. Research design. A review of domestic and foreign literature sources on the use of computer acoustic analysis and AI technologies in the diagnosis of diseases of the vocal apparatus is carried out. Material and methods. The material for the analysis was publications in scientific jour …