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European Health Evidence

The European alternative to PubMed

EUVIMED is the European alternative to PubMed: a central, multilingual research platform for medicine, nursing, life sciences and healthcare. It brings together international and European literature sources, study registries, open-access full texts, citations and retraction notices in one search. Unlike pure bibliographic databases, EUVIMED supports the entire research process – from discovery and appraisal with LIVIA and CLARA to traceable evidence synthesis. European in focus, transparent, interoperable and designed for science and healthcare.

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EUVIMED Themenbrowser · Medizin · Seite 124

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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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Aktuelle Forschung nach Fachgebiet

23 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
03.09.2026journal-article

Cereal Chemistry

Influence of Milling Methods and Cold Plasma Treatment on the Functional and Baking Properties of the Pearl Millet Flour and Bread

Bindusri Naraharasetti, Snehasis Chakraborty, Kaliramesh Siliveru, P. V. Vara Prasad

ABSTRACT Background and Objective Pearl millet, a crop with excellent resilience to harsh environmental conditions, is gluten‐free, but hard to mimic the wheat bread textural attributes. Cold plasma treatment is a non‐thermal technology that can enhance the viscosity profile and functional properties of the cereal flour. The objective of the study is to evaluate the impact of milling methods (pin mill and hammer mill) and moisture conditioning (tempered and untempered grain) on the rheological and physical properti …

03.09.2026journal-article

Frontiers in Cell and Developmental Biology

Early diagnosis of radiation-induced renal injury: from lagging indicators to multimodal, pre-fibrotic detection

Yuanyuan Zhang, Eric P. Cohen, Sean V. Murphy, Tarek Zaho, Hongbing Liu, Heather Himburg, Michael Patrick Feloney, George William Schaaf, Anthony Atala, J. Mark Cline

Background Radiation-induced renal injury (RRI) is characterized by a prolonged latent phase from radiation exposure to clinical dysfunction. Conventional markers such as serum creatinine and blood urea nitrogen (BUN) may only increase after substantial nephron loss, thereby missing a critical therapeutic window during which renal injury may remain amenable to mitigation. Objective This review synthesizes emerging strategies for the early, pre-fibrotic detection of RRI, emphasizing molecular damage biomarkers, geno …

03.09.2026journal-article

Frontiers in Health Services

Patient misidentification and data integrity risks in ultrasound imaging: a case report using multi-framework incident analysis

Benedicta Osei-Donkor, Abdallah Hassoun, Md Shafiqur Rahman Jabin

Background Digital imaging workflows depend on accurate scheduling, patient identity reconciliation, and reliable metadata continuity to ensure safe image storage and retrieval. Disruptions in these processes may not directly affect image acquisition but can delay access to imaging information and pose significant patient safety risks. Objective To examine a recurrent ultrasound workflow failure that compromised downstream image availability and to identify practical strategies for preventing recurrence. Methods A …

03.09.2026journal-article

Frontiers in Dental Medicine

Curcumin as an adjunct in periodontal therapy: local effects, delivery systems, and clinical perspectives

Ana Carolina Aparecida Rivas, Mario Taba, Paola Gomes Souza

Curcumin, the active polyphenol in turmeric (Curcuma longa), is well-known for its anti-inflammatory, antioxidant, and antimicrobial properties, making it a promising therapeutic agent for a range of diseases, including neuroinflammatory conditions and periodontal disease. Periodontitis, a prevalent oral disease, is associated with chronic inflammation and bacterial infection. Curcumin has demonstrated antibacterial effects against periodontal pathogens such as Aggregatibacter actinomycetemcomitans, Porphyromonas g …

03.09.2026journal-article

Frontiers in Medicine

Time-Series modeling for predicting mortality risk in intensive care unit patients with pulmonary inflammation

Yihai Zhai, Ruixin Xu, Haisu Lu, Siying Lv, Liqin Mo

Objective This study aims to evaluate dynamic changes in pneumonia-related mortality risk among ICU patients using time-series models and develop interpretable predictive models for early mortality assessment. Methods Data were obtained from the MIMIC-IV and eICU Collaborative Research Database. The MIMIC-IV cohort was split into training and testing sets (7:3 ratio), with external validation conducted using the eICU cohort. Missing data were handled using forward filling and multiple imputation. LSTM was used to e …

03.09.2026journal-article

Frontiers in Medicine

Design, implementation, and evaluation of a programmatic assessment model in an emergency medicine residency: a mixed-methods study

İbrahim Ulaş Özturan, Dilek Kitapcioglu, Prattama Santoso Utomo, Cansu Alyesil Ozturan, Nurettin Özgür Doğan, Elif Yaka, Serkan Yılmaz, Murat Pekdemir, Levent Altıntaş

Background Programmatic assessment (PA) is widely endorsed in postgraduate medical education, but empirical accounts of real-world implementation in emergency medicine (EM) remain limited and are concentrated in North American settings. We piloted and evaluated the design, implementation, and outcomes of a PA model in an EM residency at a high-volume tertiary care center in Türkiye. Methods A mixed-methods study was conducted over an eight-month pilot (November 2024–June 2025). Program design and evaluation followe …

03.09.2026journal-article

Frontiers in Oncology

Analysis of clinical features and outcomes in a Chinese cohort with ALK fusion across pan-cancer: a retrospective study

Meng Zhang, Yi Feng, Xue Du, Changda Qu, Meizhu Meng, Meiying Ye, Min Liang, Ziran Yang, Wenjuan Gong, Xingyu Ma, Jialiang Guo, Wenmei Li, Shuqin Jia

Background ALK fusions are validated oncogenic drivers, yet their molecular heterogeneity and therapeutic implications remain poorly characterized. This study defined the landscape of ALK fusion partners, EML4-ALK variants, and co-mutations and their impact on treatment responses in a large Chinese pan-cancer cohort. Methods We retrospectively analyzed 16,335 consecutive pan-cancer patients via next-generation sequencing to identify ALK fusions. Clinical characteristics, fusion partners, co-mutations, and treatment …

03.09.2026journal-article

Frontiers in Cardiovascular Medicine

Perimenopause as a potential window of cardiometabolic remodeling in heart failure with preserved ejection fraction: a missed opportunity for prevention

Faith Adedayo Adejumo, Oluwayimika Oluwatobi Obielodan, Fiyinfoluwa Adetoye, Nicholas Aderinto

Heart failure with preserved ejection fraction (HFpEF) disproportionately affects women and has emerged as one of the most prevalent forms of heart failure worldwide. Although the marked increase in HFpEF incidence after menopause is well recognized, the biological events that initiate disease development remain poorly defined. Most mechanistic and clinical investigations have focused on postmenopausal women or established HFpEF, leaving the menopausal transition comparatively underexplored despite growing evidence …

03.09.2026journal-article

Clinical Journal of the American Society of Nephrology

Predictive Value of Urine Tubular Biomarkers on Kidney Outcomes

Greco B. Malijan, William G. Herrington, Parminder K. Judge, Rebecca J. Sardell, Daniel Chapman, Michael Hill, Stewart Moffat, Doreen Zhu, Alfred K. Cheung, Dominik Steubl, Martin J. Landray, Christoph Wanner, Colin Baigent, Richard Haynes, Joachim H. Ix, Natalie Staplin, Michael G. Shlipak, on behalf of the EMPA-KIDNEY Collaborative Group

Background Urine tubular biomarkers have previously been associated with chronic kidney disease (CKD) progression independently of estimated glomerular filtration rate (eGFR) and albuminuria. We evaluated whether nine urine tubular biomarkers could improve prediction of kidney failure beyond serum creatinine and urine albumin-to-creatinine ratio among adults with CKD. Methods Among 5100 participants in EMPA-KIDNEY, a randomized trial which assessed the effects of empagliflozin 10 mg versus matching placebo among pa …

03.09.2026journal-article

PLOS One

Efficacy of different doses of oliceridine for Patient-Controlled Intravenous Analgesia in patients undergoing Total Laparoscopic Hysterectomy

Jiaojiao Deng, Baobao Ma, Kaihua Wei, Tao Wei, Liping Xie, Hong Zhang, Changxu Wang

Objective To evaluate the efficacy and safety of three oliceridine different doses for oliceridine for patient-controlled analgesia (PCIA) in patients undergoing during total laparoscopic hysterectomy, following the premature termination of the planned sufentanil control arm. Methods This prospective, randomized, double-blind trial was originally designed as a four-arm study. Due to operational challenges in patient recruitment and randomization within the single-center setting-specifically, significant reluctance …

03.09.2026journal-article

Journal of Cardiovascular Development and Disease

Multimodal Management of Chronic Thromboembolic Pulmonary Hypertension: A Narrative Review of Treatment Selection and Sequencing

Houda Gharsalli, Mohammed Alshahrani, Olfa Harbi, Nawal Alwadai, Abdalla M. Al-Asiri, Fatmah Alahmari, Amal Alqahtani, Najla Al-Jahash, Lobna Abbag, Saud Alqahtani, Khaled Abdulwahab Amer

Chronic thromboembolic pulmonary hypertension (CTEPH) is a treatable yet frequently underdiagnosed late complication of acute pulmonary embolism, in which incompletely resolved thromboemboli organise into fibrotic obstructions of the pulmonary arteries and, together with a secondary small-vessel arteriopathy affecting both obstructed and non-obstructed territories, raise pulmonary vascular resistance, impose right ventricular pressure overload, and—if left untreated—progress to right heart failure and death. Three …

03.09.2026journal-article

Journal of Clinical Medicine

The Impact of Glucagon-like Peptide-1 (GLP-1) Receptor Agonists on Body Composition in Individuals with Overweight and Obesity: A Systematic Review and Meta-Analysis

Miłosz Woźniak, Zofia Tarcz, Gabriela Pyczek, Julia Bogacka, Andrzej Diniejko, Alina Kuryłowicz, Artur Mamcarz, Daniel Śliż

Background/Objectives: Excess adipose tissue is associated with adverse changes in muscle metabolism and body composition. GLP-1 receptor agonists (GLP-1 RA) have transformed the treatment of obesity; however, concerns remain regarding the potential impact of treatment-associated weight loss on lean mass. This study aimed to evaluate the effects of GLP-1 RA on body composition in adults with obesity without type II diabetes mellitus (T2DM), with a particular focus on changes in lean mass. Methods: A database search …

03.09.2026journal-article

Clinical Genetics

Biallelic ABCA13 Loss‐of‐Function Variants in a Child With Neurodevelopmental Delay: A Case Report

Maya Atanasoska, Lubomir Balabanski, Daniela Avdjieva‐Tzavella, Tsvetina Veleva, Slavyana Yaneva Staykova, Irena Bradinova, Draga Toncheva, Radoslava Vazharova

ABSTRACT ABCA13 encodes ATP‐binding cassette subfamily A member 13, one of the largest members of the ABC transporter family. Rare ABCA13 variants have been reported in neuropsychiatric and neurodevelopmental phenotypes, including schizophrenia, bipolar disorder, autism spectrum disorder, intellectual disability, and developmental delay; however, the mode of inheritance remains uncertain, and most published cases have focused on heterozygous variants in the context of a possible dominant or susceptibility model. We …

03.09.2026journal-article

Journal of Medical Clinical Case Reports

Digital Distrust: Patient-Centred Communication and the Calibration of Epistemic Reliance in the Era of Online Self-Diagnosis and AI Symptom Checkers

Nonye Tochi Aghanya, Osinakachi Akuma Kalu

Background: Patients are coming to consultations informed by search engines, social media and generative AI. Clinicians may characterize this as distrust of clinicians. Actualities are messier, and our language for talking about how communication breaks down is limited. Purpose: Operationalize the concept of digital distrust, disambiguate it from related concepts with which it is often confused, and report a communication framework grounded in theory for clinical practice. Methods: Methodology is an interpretive co …

03.09.2026journal-article

Clinical Science

IRAP deficiency preserves renal function and attenuates pathology in aged mice

Sarah L Walton, Aneesa Ansari, Katrina M Mirabito Colafella, Lucinda M Hilliard Krause, Giannie Barsha, Michelle M Kett, Siew Yeen Chai, Vesna D Garovic, Kate M. Denton

Senescent cell accumulation and fibrosis play a fundamental role in kidney ageing. Our aim was to determine whether the angiotensin IV/insulin-regulated aminopeptidase (IRAP) axis of the renin-angiotensin system contributes to renal function decline, fibrosis and senescent cell accumulation in aged mice. We studied the role of IRAP in kidney aging using IRAP knockout mice, as well as in wildtype mice treated with an IRAP inhibitor. Complementary proximal tubule and collecting duct cell models were used to determine …

03.09.2026journal-article

Journal of Patient-Reported Outcomes

The SISAQOL-IMI glossary: harmonising terminology for patient-reported outcomes in cancer clinical trials

Kenth Louis Joseph, Francesca Martinelli, Lisa M. Wintner, Silène ten Seldam, Vincent Claus, Andrej Belančić, Ragnhild S. Falk, Cecilie D. Amdal, Micha J. Pilz, Corneel Coens, Martin Taphoorn, Johannes M. Giesinger, Joseph C. Cappelleri, Vivek Pawar, Kristin Bjordal

Abstract Background This study presents the development of a glossary designed to harmonize terminology, foster consensus and support the successful implementation of the Setting International Standards in Analysing Patient-Reported Outcomes and Quality of Life Endpoints in Cancer Clinical Trials-Innovative Medicines Initiative (SISAQOL-IMI) guidelines. Methodology SISAQOL-IMI consortium representatives from 41 international organisations were invited to participate in the development of the glossary. From 2021 to …

03.09.2026journal-article

Frontiers in Medicine

Global trends and thematic clusters in healthcare professional education, medical errors, and patient safety: a bibliometric analysis, 2000–2026

Birgit Hladschik-Kermer, Olena Litvinova, Michel-Edwar Mickael, Maima Matin, Ahmed Fatimi, Anass Belbachir, Mairim Russo Serafini, Maria Kletecka-Pulker, Atanas G. Atanasov, Thomas Wochele-Thoma

Background In the context of the active implementation of the World Health Organization’s Global Patient Safety Action Plan, there is a growing need for a comprehensive synthesis of scientific evidence reflecting the development of research in the field of healthcare professional education. Objective This study aims to conduct a bibliometric analysis of scientific publications addressing the relationship between healthcare professional education, medical errors, and patient safety over the period 2000–2026, based o …

03.09.2026journal-article

Sage Sphere International Journal

Cirugía laparoscópica versus cirugía robótica en la resección de tumores hepáticos: resultados y beneficios clínicos

Joel Sebastian Chango Yosa, Kelvin Alejandro Torres Quezada, Anthony Bryan Cevallos Falcones, Dana Isabel Morales Figueroa, Alonso Patricio Espinoza Ayala

Introducción: La resección hepática constituye el tratamiento principal de diversos tumores hepáticos. Los abordajes laparoscópico y robótico han ampliado las posibilidades de cirugía mínimamente invasiva, especialmente en procedimientos técnicamente complejos. Objetivo: Sintetizar la evidencia científica sobre los resultados y beneficios clínicos de la cirugía laparoscópica versus robótica en la resección de tumores hepáticos. Metodología: Se realizó una revisión bibliográfica narrativa mediante búsquedas en PubMe …

03.09.2026journal-article

NIHR Open Research

How to improve uptake and adherence to dietary trials in gestational diabetes amongst South Asian women: insights from patient and public involvement and engagement

Elizabeth Dapre, Michelle Harvie, Basil Issa, Brian McMillan, Helen Morley

Background Gestational diabetes mellitus (GDM) is associated with adverse maternal and neonatal outcomes and affects approximately 10–20% of pregnancies in the UK. The prevalence of GDM among South Asian women is around twice that of White British women, and they are also twice as likely to develop type 2 diabetes following diagnosis. Although multiple dietary interventions have been explored to improve glycaemic control in GDM, no single dietary approach has proven consistently effective in improving health outcom …

03.09.2026journal-article

Measurement Science and Technology

Tacholess order tracking based on surrogate data test for bearing diagnosis under varying speed conditions

Tao Zhang, Jiahang Li, Cheng Li, Mengjie Luo, Yi Wang

Abstract For bearing fault diagnosis, vibration analysis is one of the most primary methods in engineering practice. Many traditional methods are ineffective in engineering applications with variable operating conditions. Tacholess envelope order analysis (TLEOA) technology shows promising application prospects for bearing fault diagnosis in conditions where speed varies, since it does not require additional speed measurement equipment to obtain phase information. Nevertheless, the widespread application of this me …

03.09.2026journal-article

Frontiers in Surgery

Comparison of ACDF with stand-alone PEEK cage versus zero-p implant for the treatment of cervical degenerative disease: a systematic review and meta-analysis

Yiheng Zhao, Juan Xie, Ling Zhu, Jianna Zhang, Junhui Zhang

Introduction In recent years, stand-alone polyetheretherketone (PEEK) cages (SA) and Zero-P implants (ZP) have been widely adopted clinically in anterior cervical discectomy and fusion (ACDF) for cervical degenerative disease (CDD). However, which is superior between SA and ZP remains highly controversial. This meta-analysis was designed to conduct a head-to-head comparison of the safety, clinical efficacy, and radiological effectiveness of ACDF with ZP and SA. Methods This research was carried out in accordance wi …

03.09.2026journal-article

Frontiers in Immunology

Complete and durable remission in a patient with brain metastasis from gastric cancer treated with SRS followed by RC48 plus camrelizumab after progression on chemo-immunotherapy: a case report and literature review

Xiao Liu, Baozhen Ma, Mengjiao Yang, Lingdi Zhao

Background Brain metastasis from gastric cancer carries a dismal prognosis, with median overall survival of only 3–6 months. Patients who progress on immune checkpoint inhibitor (ICI)-containing regimens have limited salvage options. HER2-low expression (IHC 1+ or IHC 2+/FISH-negative), historically excluded from anti-HER2 therapy, has now emerged as a novel therapeutic target for antibody-drug conjugates (ADCs) such as RC48 (disitamab vedotin). Case summary A 52-year-old male with HER2-low (IHC 2+/FISH-negative), …

03.09.2026journal-article

International Journal of Legal Medicine

A technical note on the preparation and staining of unfixed, undecalcified and unembedded fresh and taphonomically altered human bone with five common stains and dyes

Simona A. Dinu, Iris Sluis, Wilma Duijst, Tristan Krap

Abstract Anthropological and forensic investigations often rely on skeletonized human remains as the only piece of evidence for lifestyle, age and post-mortem interval predictions. Recent studies have demonstrated that histological staining has the potential to extend or improve the knowledge that can be extracted from the microstructure of bone. However, histological staining has only been scarcely applied and investigated on (taphonomically altered) human bones, leading to a lack of available methodology. In this …