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Entdecken Sie tatsächlich neu veröffentlichte Arbeiten aus Medizin, Pflege, Therapie, Public Health und Life Sciences. Sortiert nach Publikationsdatum, nicht nach Zitierhäufigkeit.

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24 neue Nachweise auf dieser Seite Publiziert in den letzten 30 Tagen Neueste zuerst Crossref DOI
19.08.2026journal-article

Discover Public Health

The evolving relationship between public health and midwifery in the United Kingdom

Bethany Fletcher, Jillian C. M. Ireland, Edwin van Teijlingen

Abstract Readers will agree that public health and health promotion are the responsibility of everybody, not just those working in the field of public health. For this reason, health promotion and disease prevention have long been part of the midwife’s role. However, in several countries, such as the United Kingdom, the role and responsibilities of the midwife have expanded over the decades to incorporate additional public health issues. Many of these new public health tasks may require a lot of training and educat …

19.08.2026journal-article

Zeitschrift für Gastroenterologie

Retroperitoneal solitary fibrous tumour with Doege-Potter-Syndrome – successful interventional therapy

Nico Heß, Ali Seif Amir Hosseini, Carolin Sobotta, Giovanni Frederico Torsello, Florian Bösch, Neriona Vorpsi, Philipp Ströbel, Albrecht Neesse

Abstract Solitary fibrous tumours (SFTs) are rare mesenchymal neoplasms that may cause insulin-independent hypoglycaemia (Doege-Potter-syndrome). Although surgical resection is the standard treatment, non-surgical options may be required for elderly or multimorbid patients. An 82-year-old woman presented with severe nocturnal hypoglycaemia (

19.08.2026journal-article

Inflammatory Bowel Diseases

Coccidioidomycosis in patients with inflammatory bowel disease receiving advanced therapy: An observational study from an endemic tertiary center

Fares Jamal, Alejandro J Gonzalez, Geoff Thomas, Taylor Viggiano, Sandra Elmasry, Abdullah Hamad, Marina I Ivanov, Erin J Kaleta, Guilherme P Ramos, Nathan L Delafield, Janis E Blair, Talha A Malik

Abstract Background Immunosuppression is a recognized risk factor for severe and disseminated coccidioidomycosis; however, data describing outcomes in patients with inflammatory bowel disease (IBD) receiving advanced therapy, including biologics and small molecules, remain limited. We aim to describe the prevalence, clinical presentation, treatment patterns, and outcomes of coccidioidomycosis in IBD patients receiving advanced therapy at an endemic tertiary care center. Methods We performed a retrospective observat …

19.08.2026journal-article

ACS Applied Nano Materials

Engineered Red Blood Cell-Derived Nanovesicles Functionalized with cRGD Peptide and Loaded with Acevaltrate for Targeted Ferroptosis Therapy of Triple-Negative Breast Cancer

Fulan Yang, Xun Xi, Yue Yu, Xin Wang

Abstract Triple-negative breast cancer (TNBC) remains a highly aggressive breast cancer subtype with limited molecularly targeted treatment options, while acevaltrate (ACE), a natural dual-target ferroptosis inducer, is constrained by poor aqueous solubility and insufficient tumor accumulation. Here, we engineered cyclic Arg-Gly-Asp (cRGD)-functionalized red blood cell-derived nanovesicles (RNVs) physically encapsulating ACE (cRGD-RNV@ACE) for integrin αvβ3-targeted ferroptosis therapy. The nanovesicles preserved c …

19.08.2026journal-article

JBI Evidence Implementation

Nutritional risk management for stroke survivors with dysphagia in a rehabilitation department: a best practice implementation project

Qiuxiang Mi, Dandan Qu, Li Wang, Xirongguli Halili, Yuping Chen, Xianwen Fan, Chenghui Wu, Canzhi Zhang, Lan Zhou, Min Xiao, Qirong Chen

ABSTRACT Introduction: Stroke survivors with dysphagia face a greater risk of malnutrition and life-threatening complications, yet evidence-based nutritional management in this population remains underutilized in clinical practice. Objective: This project aimed to implement and evaluate an evidence-based standardized nutritional risk management program for stroke survivors with dysphagia in a rehabilitation department in a hospital in China. Methods: This evidence implementation project was conducted using the JBI …

19.08.2026journal-article

Egyptian Rheumatology and Rehabilitation

Assessment of thyroid gland disorders in patients with psoriatic arthritis after anti-tumor necrosis factor therapy

Rehab Mahmoud Salem, Heba Ahmed Almokadem, Rania Elsaied Elkholy, Thanaa F. Mansour, Yousra Fouad Mohamed Rashad, Radwa H Shalaby

Abstract Objectives To evaluate the effect of anti-tumor necrosis factor (anti-TNF) therapy on thyroid gland functionality and morphological characteristics in anti-TNF naïve psoriatic arthritis (PsA) patients. Methods 60 adult patients with PsA were included in a prospective study, all exhibiting moderate to severe disease activity as per Disease Activity in Psoriatic Arthritis (DAPSA) score despite conventional therapy and were subsequently planned to initiate biological therapy as part of standard clinical manag …

19.08.2026journal-article

International Journal of Molecular Sciences

From Physicochemical Properties to Rehabilitation Outcomes: Understanding Corticosteroid Injection Adverse Effects

Carmelo Pirri, Nicola Manocchio, Andrea Sorbino, Valeria Napoleoni, Anna D’Amato, Nina Pirri, Calogero Foti

Corticosteroid injections (CSIs) are widely used in Physical and Rehabilitation Medicine, but their safety profile is strongly influenced by the formulation-specific chemical structure and physicochemical properties of each molecule, as well as by injection technique and dosing strategy. Particulate corticosteroids such as triamcinolone acetonide and methylprednisolone acetate exhibit low aqueous solubility, microcrystal formation, and prolonged intra-articular residence, which translate into sustained anti-inflamm …

19.08.2026journal-article

Frontiers in Immunology

Infection risk associated with talquetamab in relapsed/refractory multiple myeloma: a systematic review with meta-analysis of talquetamab monotherapy and descriptive analysis of combination therapy

Zeng-Yi Huang, Weilong Wu, Gaoyu Luo, Hui Huang, Xiao-Lian Liu

Background Talquetamab, a first-in-class G protein–coupled receptor family C group 5 member D (GPRC5D) × CD3 bispecific antibody, demonstrates substantial clinical activity in relapsed/refractory multiple myeloma (RRMM). However, immune dysfunction associated with advanced disease, extensive prior therapies, and bispecific antibody–mediated immune modulation may increase susceptibility to infections. This systematic review and meta-analysis aimed to characterize infection risk associated with talquetamab, with sepa …

19.08.2026journal-article

Cancers

Sexual Dysfunction in Cervix Cancer Survivors After Surgery and/or Radio(chemo)therapy: A Bayesian Network Analysis Based on the SENECA Study Cohort

Adriel Ngo, Kari Tanderup, Therese Juul, Gunn Ammitzbøll, Jakob Tanderup, Peter Christensen, Susanne O. Dalton, Lars U. Fokdal, Christoffer Johansen, Susanne K. Kjær, Monica Serban

Background: To better understand the complexity of sexual dysfunction, we aim to construct multi-factorial explanatory models of sexual dysfunction using data from participants enrolled in the Danish cross-sectional Study of latE effects for those liviNg through cErvical CAncer (SENECA). Methods: In a nationwide survey, patient-reported outcomes (PRO) were collected from 2002 cervical cancer survivors treated with surgery and/or radio(chemo)therapy between 2005–2020 and a reference cohort consisting of 7853 women w …

19.08.2026journal-article

Vasa

2-Year outcomes of endovascular therapy of popliteal artery restenosis

Tanja Böhme, Elias Noory, Ulrich Beschorner, Frank Güntert, Jonas Salm, Roaa Bollenbacher, Dirk Westermann, Thomas Zeller

Summary: Background: To assess the mid-term outcome of endovascular treatment for popliteal artery restenosis. Patients and methods: This retrospective study included patients with peripheral artery disease (Rutherford class (RC) 2–5) and popliteal artery restenosis treated between January 2007 and December 2017. Patients were classified into four groups based on lesion extent: isolated popliteal lesions and lesions extending to femoral and/or below-the-knee arteries (BTK). The primary endpoint was target lesion re …

19.08.2026journal-article

Человеческий капитал

ИНТЕГРАЦИЯ ЦИФРОВЫХ ИНСТРУМЕНТОВ В ПРАКТИЧЕСКУЮ ПОДГОТОВКУ БУДУЩИХ ЛОГОПЕДОВ ПОСРЕДСТВОМ ВИРТУАЛЬНЫХ ДИАГНОСТИЧЕСКИХ СИМУЛЯТОРОВ

З.Р. Егорова

В статье рассматривается проблема интеграции цифровых инструментов в практическую подготовку будущих логопедов. Актуальность исследования обусловлена необходимостью преодоления разрыва между теоретическим освоением содержания логопедических дисциплин и формированием опыта самостоятельного распознавания и дифференциации нарушений звукопроизношения. Цель статьи состоит в теоретическом обосновании и описании архитектуры виртуального диагностического симулятора, предназначенного для формирования и оценки знаниевого и д …

19.08.2026journal-article

Open Forum Infectious Diseases

Transforming Human Immunodeficiency Virus Outcomes: Impact of a Rapid Antiretroviral Therapy Model on Linkage to Care and Viral Suppression in Memphis, Tennessee

April C Pettit, Paridhi Ranadive, Aima A Ahonkhai, Agatha Eke, Damian J Denson, Leslie J Pierce, Latrice C Pichon, Brittany Wilbourn, Carolyn M Audet, Peter F Rebeiro

Abstract Background In May 2024, a locally tailored, multicomponent rapid antiretroviral therapy intervention—Connextion—was launched in Memphis, Tennessee, a priority jurisdiction of the Ending the HIV Epidemic in the US initiative. This study assessed its impact on time to care linkage and viral suppression among newly diagnosed individuals with human immunodeficiency virus (HIV). Methods We included adults newly diagnosed with HIV between January 2022 and May 2025 at participating Connextion sites, who were iden …

19.08.2026journal-article

Frontiers in Digital Health

Outside the healthy bounds: reference intervals for population and individual-level medical speech analysis

Pascal Hecker, Monica Gonzalez-Machorro, Catarina Botelho, Helly Hammer, Hesam Sagha, Matthias Kahlau, Robert Hoepner, Florian Eyben, Björn W. Schuller, Bert Arnrich

Reference intervals (RIs) are a well-established clinical tool for defining healthy bounds of laboratory measures. Recently, they have been applied to acoustic features extracted from speech to provide a transparent and disorder-agnostic perspective on symptomatic speakers. We evaluate the potential and limitations of RIs across three datasets: clean, laboratory recordings from people with multiple sclerosis (pwMS) and two noisy datasets targeting respiratory symptoms and work-related stress, collected under everyd …

19.08.2026journal-article

World Journal of Psychiatry

Comprehensive psychological and neurological rehabilitation for post-stroke depression: A retrospective comparative study with biomarker exploration

Shan-Zhong Yan, Zeng-Yan Hu, Hong-Ying Zhou, Song Chai

BACKGROUND Post-stroke depression (PSD) is one of the most common and debilitating neuropsychiatric sequelae after ischemic stroke, with a prevalence of 30%-50%, which significantly hinders neurological recovery, participation in rehabilitation, and long-term quality of life. Although the clinical burden of stroke is high, integrated rehabilitation strategies that effectively combine structured psychological rehabilitation with its neurological counterpart are under-defined. The best combination of interventions an …

19.08.2026journal-article

Surgical Endoscopy

Laparoscopic Heller–Dor as salvage therapy after failed POEM: a prospective comparative study

Irene Sole Zuin, Tommaso Garbo, Luca Provenzano, Francesca Forattini, Giovanni Capovilla, Matteo Santangelo, Arianna Vittori, Matteo Pittacolo, Giulia Nezi, Matteo Ghisa, Edoardo Vincenzo Savarino, Lucia Moletta, Loredana Nicoletti, Michele Valmasoni, Renato Salvador

Abstract Objectives Current therapeutic options for esophageal achalasia (EA) include pneumatic dilation (PD), laparoscopic Heller–Dor myotomy (LHD), and peroral endoscopic myotomy (POEM), which has gained increasing popularity over the last decade. However, symptoms persist or recur after POEM in 10–20% of cases. Evidence on management of POEM failures is limited to small case series. This study evaluates the outcome of LHD in patients who previously underwent endoscopic treatment—POEM or PD—as compared to treatme …

19.08.2026journal-article

Journal of Speech, Language, and Hearing Research

Chirp-Evoked Electrocochleography and Speech-in-Noise Performance in Normal-Hearing Individuals With Tinnitus

Tzu-Yuan Wang, Yu-Fu Chen, Chin-Kuo Chen, Chi-Ting Chang

Purpose: Both tinnitus and poor hearing-in-noise performance have been proposed as perceptual consequences of cochlear synaptopathy, which can occur in the absence of significant hearing loss. However, to date, no study has investigated chirp-evoked electrocochleography (ECochG) measures or examined the relationship between action potential (AP) amplitude and speech perception in noise (SPIN) performance in normal-hearing individuals with tinnitus. Method: Twenty participants with nonpulsatile tinnitus lasting at l …

19.08.2026journal-article

Poznan Studies in Contemporary Linguistics

Orthographic effects in the pronunciation of English borrowings in Polish: evidence from attested pronunciations and Text-to-Speech systems

Jarosław Weckwerth, Dawid Pietrala

Abstract This paper investigates the pronunciation of English borrowings in Polish, focussing on how orthography influences their phonological adaptation. Two complementary studies are presented. Study 1 examines the attested pronunciations of over 200 English borrowings in Polish extracted from Polish-language YouTube videos. Study 2 analyzes the output of two commercial Text-to-Speech systems (Google and Microsoft) when rendering 184 company names with English material embedded in Polish carrier sentences. The pa …

19.08.2026journal-article

Frontiers in Immunology

Predictors of subsequent relapse-independent progression after high-efficacy therapy in relapsing multiple sclerosis

Matteo Foschi, Andrea Surcinelli, Ivan Panzera, Ludovica Maria Miserocchi, Giorgia Balducci, Luca Mancinelli, Cristiana Ganino, Francesca Graziano, Ester Lagonigro, Maria Di Ioia, Valeria Di Tommaso, Deborah Farina, Giovanna De Luca, Massimo Caulo, Maria Grazia Piscaglia, Stefano Luca Sensi, Valentina Tomassini

Background and objectives Progression independent of relapse activity (PIRA) is increasingly recognized as a major driver of disability accumulation in multiple sclerosis (MS). However, the factors associated with PIRA occurring after initiation of high-efficacy therapies (HETs) remain poorly investigated. We aimed to identify clinical predictors of subsequent PIRA following first HET initiation. Methods We retrospectively analyzed data from two prospectively maintained Italian MS registries. Adults with relapsing …

19.08.2026journal-article

Cancer Causes & Control

Characterizing primary care in breast cancer survivors after completion of cancer therapy

Kendall Kay, Yancen Pan, Jessica Li, Lan Zhang, Vanessa N Torres, Yelba Castellon-Lopez, Meng-Han Tsai, Geetanjali D Datta, Jennifer Henry, Cody Ramin

Abstract Purpose Despite the potential for primary care to optimize comorbidity management among breast cancer survivors, engagement with primary care providers (PCPs) remains low. This study comprehensively examined PCP-led care after breast cancer treatment to identify survivors who may benefit from targeted interventions to improve primary care engagement. Methods We identified 1,582 posttreatment breast cancer survivors from the U.S. Behavioral Risk Factor Surveillance System survey. Weighted multivariable-adju …

19.08.2026journal-article

Pediatric Hematology/Oncology and Immunopathology

The effectiveness of local methods of treatment in patients with germ cell tumors who have exhausted all curative options of systemic therapy. Clinical case report and literature review

Polina A. Naymushina, M. A. Toporkov, L. L. Rabaeva, M. M. Strozhenkov, N. V. Zhukov

Introduction. With adequate initial therapy, germ cell tumors (GCTs) have a relatively favorable prognosis; however, approximately 20–25% of patients experience relapse or refractory disease. Currently, there are several potentially curative treatment options for this patient population but the optimal approach remains undetermined in both adult and pediatric practice. A particular challenge is the management of patients who have not responded to multiple lines of systemic therapy. Although most GCTs are considered …

19.08.2026journal-article

Journal of Health and Allied Sciences NU

Early Physiotherapy With Bimanual Intensive Training in a Child With Miller Fisher Syndrome: A Rare Case Report

Dhanashree Deshmukh, Mandar Malawade, Dhirajkumar Arun Mane

Miller Fisher syndrome (MFS) is a rare variant of Guillain-Barré syndrome (GBS), which typically affects adults, but paediatric cases are rare. There is insufficient evidence on the motor recovery strategies, task-specific rehabilitation, and neuroplasticity-based intervention in paediatric neuro-immune conditions like MFS. This case report describes a 4-year-old male child who developed MFS following a gastrointestinal infection. The child presented with progressive bilateral upper limb weakness. Clinical features …

19.08.2026journal-article

Indonesian Journal of Global Health Research

Effectiveness Music Therapy in Reducing Pain and Anxiety in Preschool Children in the Emergency Room: Literature Review

Cindy Ratna Ardella, Ekan Faozi

The Emergency Department (ED) is a healthcare setting with a high risk of causing pain and anxiety in pediatric patients due to invasive procedures and emergency situations. If these conditions are not properly managed, they can negatively impact the care experience and increase the risk of psychological trauma. Music toy therapy, as a non-pharmacological intervention based on active distraction, has the potential to reduce pain and anxiety in children in the ED. This literature review aims to analyze the latest sc …

19.08.2026journal-article

Translational Psychiatry

Changes in speech reflect changes in psychotic symptom severity: a longitudinal natural language processing analysis

Sandra Anna Just, Shrankhla Pandey, Dina Stein, Ivan Nenchev, Anna-Lena Bröcker, Christiane Montag, Sarah E. Morgan

Abstract The usefulness of automated speech and language markers to monitor or predict psychotic symptoms depends on their ability to detect changes in mental state. To date, research linking psychosis and Natural Language Processing (NLP) has been conducted almost exclusively using cross-sectional experimental designs, limiting insight into how intraindividual speech changes relate to symptoms and functioning. Therefore, here we examined the speech of 95 individuals diagnosed with schizophrenia ( n = 70) or schizo …