Digital Health: neue Gesundheitspublikationen – Seite 113

07.09.2026journal-article

Journal of Hospital Medicine

Early clinical and laboratory indicators for differentiating infectious from autoimmune encephalitis in pediatric patients: A single‐center retrospective cohort study

Ruth Vela Sosa, Audrey Uong, Alvaro Coronado‐Muñoz

Abstract Background Pediatric encephalitis is associated with significant morbidity. Early recognition of autoimmune encephalitis (AE) is critical for timely immunotherapy and improved outcomes. Objectives To externally validate a previously published adult encephalitis prediction model in a pediatric cohort and identify predictors of pediatric AE. Methods This retrospective single‐center study included children 90 days to 21 years with encephalitis between January 2016 and September 2025. Clinical and laboratory d …

07.09.2026journal-article

V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY

Clinical diagnosis of PTSD and the severity of comorbid symptoms in military personnel with combat experience

M. L. Baranov, Yu. A. Chaika

Background . In military personnel with combat experience, posttraumatic symptoms frequently co-occur with anxiety, depressive symptoms, and anger-related manifestations, making it difficult to distinguish PTSD from other stress-related disorders when relying solely on screening instruments. Clinical verification is therefore essential not only for evaluating the diagnostic utility of self-report measures, but also for clarifying the structure of comorbid emotional symptoms. Objective . To assess, in a clinically e …

07.09.2026journal-article

Sustainable Social Development

Public health financing as a driver of economic growth and equity: Evidence from Morocco

Elmaati Errachiq, Redouane Kaiss, Nabil Ouarsafi, Abderraouf Hilali

This paper analyzes the economic growth and health financing in Morocco in connection with the importance of health investment to sustainable economic growth. The available literature indicates that the enhancement of population health is one of the factors that help an economy to improve, especially when governments decide to allocate more funds to the health sector and also enhancing access to health care services. A healthier population is also likely to be more productive which will improve labor efficiency, de …

07.09.2026journal-article

Epileptic Disorders

Functional (dissociative) seizures in PCDH19 ‐clustering epilepsy: Clinical characteristics and diagnostic challenges

Rita Cagigal, Javier Peña‐Ceballos, Patrick B. Moloney, Elena González‐Alguacil, Nuria Lamagrande, Ethan Tennant, Maria Jesus Martínez‐González, Victor Gomez‐Mayordomo, Andrea Garcia‐Ortega, Radu‐Ștefan Perjoc, Oana‐Aurelia Vladâcenco, Kette Valente, Rhys H. Thomas, Victor Soto‐Insuga, Norman Delanty, Rikke S. Møller, Ángel Aledo‐Serrano

Abstract Objective Functional (dissociative) seizures (FDS) are increasingly recognized among individuals with epilepsy, intellectual disability (ID), and psychiatric disorders, but their occurrence in PCDH19‐clustering epilepsy (CE) has not been systematically described. We aimed to characterize the clinical features, diagnostic pathways, and management of FDS in individuals with genetically confirmed PCDH19‐CE. Methods We conducted a multicenter retrospective study across six tertiary European Epilepsy Centers. I …

07.09.2026journal-article

Urban Informatics

The characteristic analysis and pattern classification of Beijing’s commercial districts based on multi-source geographical big data

Zonghan Yang, Ci Song, Peiqi Wang, Xiaotong Wang, Dayu Cheng, Cheng Zhang, Bo Zheng, Daojing Zhou, Tao Pei

Abstract Commercial districts, as key hubs for diverse commercial activities, play a crucial role in urban life. Yet in recent years, the vitality of commercial districts is declining. Although various strategies for revitalizing commercial districts have been proposed, it’s essential to first understand their conditions before any interventions are made. Traditional studies primarily focus on locational, operational, and service characteristics of commercial districts, yet they suffer from limitations such as poor …

07.09.2026journal-article

World Journal of Economics and Business Research

ARTIFICIAL INTELLIGENCE-ENABLED REGTECH FOR KYC, FINANCIAL COMPLIANCE, AND REGULATORY REPORTING: APPLICATIONS, RISKS, AND FUTURE DIRECTIONS

Yun Li, HongZhe Zhang

Financial institutions face growing volumes of customer, payment, ownership, and regulatory data while remaining accountable for risk-based compliance decisions. Artificial intelligence-enabled regulatory technology can assist this work by combining digital identity services, entity resolution, rules, machine learning, graph analytics, natural language processing, and workflow automation. This narrative review explains the technical architecture of such systems and examines their use in know-your-customer procedure …

07.09.2026journal-article

International Journal of Environmental Research and Public Health

Agreement Between Six-Minute Walk Test-Based Equations and Bruce-Derived Aerobic-Fitness Estimates in Adults with Metabolic Syndrome: A Single-City Cross-Sectional Method-Comparison Study

Anahy Ordóñez-Zea, Alberto Urzúa, Jorge Méndez-Cornejo, Edgardo Rojas-Mancilla, Carmen Zambrano-Bravo, Esteban Oñate-Henríquez, Trinidad Parada, Cristian Vidal-Silva

Accessible assessment of aerobic fitness is important for adults with metabolic syndrome when cardiopulmonary exercise testing is unavailable. This study aimed to evaluate participant-level agreement between Six-Minute Walk Test (6MWT)-based equations and estimates derived from total Bruce treadmill duration. Using a single-city cross-sectional method-comparison design, 105 newly recruited adults, comprising 67 women and 38 men, completed standardized 6MWT and graded treadmill assessments. Agreement was evaluated u …

07.09.2026journal-article

Frontiers in Microbiology

Analysis of gut microbiota and fecal/plasma short-chain fatty acids in non-dialysis renal anemia patients: associations with clinical parameters

Lin Yang, Lifen Liu, Pingping Kong, Wenwen Xu, Zhiyuan Wang, Siqi He, Jing Lou, Yanna Dou

Renal anemia is one of the most common complications of chronic kidney disease (CKD). This study investigated gut microbiota composition and fecal/plasma short-chain fatty acids (SCFAs) in 30 non-dialysis renal anemia patients and 20 healthy controls. Gut microbiota was assessed by 16S rRNA gene amplification sequencing and SCFAs were measured using gas chromatography-tandem mass spectrometry (GC–MS/MS). Compared with healthy controls, renal anemia patients showed distinct gut microbiota composition, including high …

07.09.2026journal-article

BMC Emergency Medicine

Development and internal validation of a simple EMS-based clinical score for predicting 24-hour mortality among older adult trauma patients: a retrospective single-centre cohort study

Thongpitak Huabbangyang, Pramote Papukdee, Adisak Nithimathachoke

Abstract Background Early prediction of short-term mortality among older adult trauma patients in prehospital settings remains challenging. This study aimed to develop and internally validate a simple emergency medical services (EMS)-based clinical score for predicting 24-hour mortality among older adult trauma patients using routinely available prehospital variables. Methods This retrospective, registry-based, single-center cohort study included 665 trauma patients aged ≥ 60 years who were transported by EMS to a …

07.09.2026journal-article

Transfusion

First molecularly characterized Para‐Bombay phenotype in Iraq: Clinical, serological and genetic insights with implications for transfusion safety

Dhargam Muhamed Aljebouri, Mohammed Aljadiri, Bassam Alshaikhli, Rawa Alattabi, Arwa Alkhamess, Sajjad Aldoori, Yousif Suleiman

Abstract Background H‐deficient states are important in ABO‐related transfusion practice. Patients may be misclassified as group O if testing stops at forward ABO typing. Anti‐IH may render group O units incompatible and increase hemolysis risk. Study Design and Methods A 70‐year‐old Iraqi man was referred for failure to obtain compatible blood before knee arthroplasty. ABO testing, crossmatching, antibody screening, anti‐H lectin testing, saliva inhibition and molecular analysis of fucosyltransferase 1 (FUT1) and …

07.09.2026journal-article

Ciencia Latina Revista Científica Multidisciplinar

Factores de Éxito y Barreras Institucionales en la Adopción de la Teleenfermería y la Salud Digital: Una Revisión Sistemática

Amy Lara Rejas Samaniego, Elita Hoyos Muñoz, Aldo Fernando Rejas de la Peña, Eddy Ronald Diaz Salvatierra

La adopción de la teleenfermería y la salud digital enfrentó obstáculos institucionales que la literatura científica no siempre documentó con suficiente profundidad, pese a los avances normativos impulsados en distintos países. Ante ese vacío, la presente revisión sistemática tuvo como objetivo de investigación identificar y sintetizar los factores de éxito y las barreras institucionales reportados en la literatura científica sobre la adopción de la teleenfermería y la salud digital. Metodológicamente, el estudio s …

07.09.2026journal-article

Thrombosis and Haemostasis

Clinical Characteristics and Early Outcomes of Acute Pulmonary Embolism Presenting with Syncope

Marina López-Rubio, Victor Manuel Martínez-Castilla, Andrea Cobo-Bustamante, Lorena Sanz-Tejeiro, Rubén Alonso-Beato, Lucía Ordieres-Ortega, Crhistian-Mario Oblitas, Luis Antonio Álvarez-Sala Walther, Francisco Galeano-Valle, Pablo Demelo-Rodriguez

Abstract The prognostic significance of syncope in patients with acute pulmonary embolism (PE) remains uncertain. We assessed its association with early outcomes and explored whether distinct clinical phenotypes could be identified within this group. We analyzed a prospectively collected single-center cohort of patients with confirmed symptomatic PE diagnosed between 2010 and 2025, grouped by syncope at presentation. The primary outcome was a 30-day composite of all-cause mortality, major bleeding, and recurrent ve …

07.09.2026journal-article

Scientia fructuosa

Startup ecosystem of Albergo Diffuso: digital orchestration of value co-creation

Sergiy KRAVTSOV

The article addresses the problem of the infrastructure gap and high entry barriers to the Ukrainian hospitality industry during the recovery period. The research hypothesis states that transforming the traditional scattered hotel framework into a digital-centric ecosystem enables decentralised destinations to overcome infrastructure gaps and achieve economic resilience via an Asset-Light strategy, which compresses initial capital requirements by systematically integrating pre-existing commu¬nity housing assets thr …

07.09.2026journal-article

Scientia fructuosa

Gamification in digital branding

Vladyslav ROZHDESTVENSKYY

The article examines the impact of gamifycation on the formation of digital consumer loyalty within digital branding. It demonstrates that gamification is no longer merely a tactical tool for attracting attention but is becoming a strategic mechanism for managing usersʼ behavioural activity and emotional interaction with a brand. In conditions of intense competition, digital saturation, and information overload, gamified interactions contribute to increased engagement, stimulation of repeated actions, and the dev …

07.09.2026journal-article

Digital Solutions and Artificial Intelligence Technologies

Formation of a Unified Alphabet of Ancient Turkic Dialects for Image Annotation

A. D. Borodina, M. V. Kyzyl-ool, R. A. Kochkarov

This paper is devoted to the development of a uniﬁed alphabet of Ancient Turkic dialects for solving the problems of automated recognition of Orkhon–Yenisei runic inscriptions. The relevance of the study is determined by the fragmentation of existing rune classiﬁcations and the absence of a uniﬁed system for correlating symbols across different sources and regions, which complicates the formation of compatible datasets and reduces the efﬁciency of computer vision models. The research is to create a uniﬁed alphabet …

07.09.2026journal-article

Sinusitis

Hyperbaric Oxygen Therapy in Sinonasal Disease: A Narrative Review of Mechanisms, Clinical Evidence, and Multidisciplinary Perspectives on Invasive Fungal Rhinosinusitis and Post-Radiotherapy Injury

Daniele Salvatore Paternò, Luigi La Via, Antonino Maniaci, Mario Lentini, Adriana Cordalonga, Caterina Maria Testa, Francesco Piccitto, Enrico Provinzano, Paolo Tummino, Emilia Concetta Lo Giudice, Massimiliano Sorbello

Background: Hyperbaric oxygen therapy (HBOT) is proposed as an adjunct in two sinonasal conditions of high morbidity: acute invasive fungal rhinosinusitis (AIFRS) and post-radiotherapy injury. Methods: We conducted a narrative review and reported it against SANRA; PubMed/MEDLINE was searched (1980–2026; 1414 records screened, 589 retained), with Cochrane, society guidance and reference screening. Results: No randomised trial has tested HBOT against sinonasal endpoints in either indication. In AIFRS the dedicated ev …

07.09.2026journal-article

Sport Sciences for Health

Acute caffeine and 30-m sprint performance in female collegiate team-sport athletes: a preliminary, exploratory crossover trial

Zacharias Papadakis, Vinicius L. Ribeiro, Claire Egret, Tal Amasay

Abstract Female athletes remain underrepresented in sports nutrition research, and the efficacy of NCAA-compliant caffeine doses (~ 6 mg·kg⁻ 1 ) for sprint performance is debated. This report examined whether acute caffeine alters 30-m sprint performance in female collegiate team-sport athletes and explored sport-specific responses. In a randomized, placebo-controlled, double-blind crossover, 21 NCAA Division II athletes (basketball, soccer, softball) ingested 6 mg·kg⁻ 1 anhydrous caffeine or placebo 60 min before …

07.09.2026journal-article

Journal of Cardiovascular Development and Disease

Catheter-Based Renal Denervation in Uncontrolled and Resistant Hypertension: Evidence, Guidelines, Special Populations and Clinical Implementation

Ioannis Skalidis, Leonidas Koliastasis, Panayotis K. Vlachakis, Anastasios Apostolos, Maria Bozika, Kassiani-Maria Nastouli, Nicolas Amabile, Philippe Garot, Thomas Hovasse, Mariama Akodad, Livio D’Angelo, Antoinette Neylon, Thierry Unterseeh, Roswitha Schreier, Giacomo Maria Cioffi, Julius Jelisejevas, Peter Wenaweser, Pascal Meier, Mario Togni, Stephane Cook

Hypertension remains the leading modifiable cause of cardiovascular death, yet fewer than one in four treated adults achieves guideline-recommended blood pressure targets. Catheter-based renal denervation interrupts efferent and afferent renal sympathetic signalling and lowers blood pressure continuously and independently of medication adherence. After a decade of controversy following the neutral SYMPLICITY HTN-3 trial, a coherent body of second-generation sham-controlled randomised evidence, generated with radiof …

07.09.2026journal-article

Russian Journal of Transplantology and Artificial Organs

Kidney transplant program at the Chelyabinsk Regional Clinical Hospital

D. A. Altman, A. E. Poltorak, L. Yu. Zhuravleva, I. Ya. Bondarevsky, A. V. Gogolevskaya, B. H. Sarsenbaev, M. A. Poltorak, A. G. Istomin, A. S. Ryzhikh, P. A. Zasypkina

Objective: to evaluate the outcomes of kidney transplants performed at Chelyabinsk Regional Clinical Hospital between 2015 and 2025. Materials and methods . A retrospective analysis was conducted of 148 medical records of patients who underwent a kidney transplant (KT). The parameters assessed were recipient age and sex, duration of hemodialysis prior to transplantation, underlying cause of end-stage chronic kidney disease, duration of surgery and hospitalization, cold ischemia time, graft function, occurrence of a …

07.09.2026journal-article

Journal of Sociology, Psychology and Religious

Influence of Healthcare Workers' Knowledge in Addressing Mental Health Issues in the Provision of Holistic Care at Mombasa Hospital

Diana F. Apiyo Owino, Rebecca Wachira, Anastacia Muriithi

The purpose of the study was to investigate the influence of healthcare workers' knowledge in addressing mental health issues in the provision of holistic care at Mombasa Hospital. This study adopted a descriptive mixed-methods design, combining quantitative and qualitative approaches to provide a comprehensive understanding of the research problem. The target population in this study comprised 158 nurses and 11 resident doctors. From this, a sample size of 124 (113 nurses and 11 doctors) was selected via stratifie …

07.09.2026journal-article

Journal of Clinical Laboratory Analysis

MicroRNA ‐Mediated Autophagy and Cardiovascular Diseases: Exploring the Crossroads of Atherosclerosis and Beyond

Sepehr Ebrahimi‐Dehkordi, Amir Hossein Barjasteh, Aida Zarei, Sina Bazmi, Sarah Vaseghi, Sara Ashna, Amirreza Solati, Ali Yousefzadeh, Bita Safarzadeh Nasrabad, Zahra Mohammadi, Hamed Haddad Kashani, Mohammad Hossein Pourhanifeh

ABSTRACT Background Atherosclerosis (AS) is a complex cardiovascular disease characterized by the accumulation of lipids, inflammatory cells, and fibrous materials within arterial walls. Autophagy plays a critical role in maintaining cellular homeostasis and regulating lipid metabolism in vascular cells. MicroRNAs (miRNAs), small non‐coding RNA molecules involved in post‐transcriptional gene regulation, have emerged as key modulators of autophagy and contributors to AS progression. Methods This review synthesizes c …

07.09.2026journal-article

International Journal of Innovative Science and Research Technology

Geospatial Assessment of Spatial Distribution and Accessibility of Primary Health Care Centres in Abuja Municipal Area Council, Federal Capital Territory, Nigeria

Y. Ilemona, G. K. James, V. T. Salami, M. Ismail, B. S. Darwang, A. Earnest, I. M. Bako, O. Belenda

Background: Rapid urbanization and population growth create increasing demands for accessible and adequately distributed primary health-care (PHC) services. Geographic Information Systems (GIS), remote sensing and field-based geographic data provide a practical framework for assessing where health facilities are located, how they relate to transport networks, and where service gaps occur. This study assessed the spatial distribution, geographic accessibility and selected facility characteristics of PHC facilities i …

07.09.2026journal-article

Journal of Clinical Psychopharmacology

The Antidepressant Effects of the mGlu2/3 Receptor Antagonist TS-161 in Treatment-Resistant Depression

Mark D. Kvarta, Mai Watanabe, Satoshi Ozaki, Dede Greenstein, Adam Fijtman, Gregory Jones, Hiroe I. Hu, Solaleh Azimipour, Peixiong Yuan, Jenessa N. Johnston, Jennifer W. Evans, Jessica R. Gilbert, Carlos A. Zarate

Background: Like ketamine, group II metabotropic glutamate receptor (mGluR2/3) antagonists increase glutamate release and monoaminergic signaling, promote synaptic plasticity, and show antidepressant-related activity in preclinical models. A recent phase I trial of the orthosteric mGluR2/3 antagonist prodrug TS-161 established its safety, tolerability, and pharmacokinetic profile. Methods: This phase IIa randomized, placebo-controlled, double-blind, crossover, proof-of-concept, single-site trial was designed to eva …

07.09.2026journal-article

IIARD INTERNATIONAL JOURNAL OF ECONOMICS AND BUSINESS MANAGEMENT

Impact of Artificial Intelligence and Technology on Labour Relations

Festus Usifo

The rapid advancement of artificial intelligence (AI) and automation is transforming the global workforce, reshaping job structures, skill requirements, and labour relations. This study examines the impact of AI on employment dynamics, focusing on three critical areas: job displacement, evolving skill demands, and the changing role of human resource management (HRM). Evidence from existing literature indicates that while AI-driven technologies displace routine and repetitive jobs, they also generate new opportuniti …

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Aktuelle Forschung nach Fachgebiet

Early clinical and laboratory indicators for differentiating infectious from autoimmune encephalitis in pediatric patients: A single‐center retrospective cohort study

Clinical diagnosis of PTSD and the severity of comorbid symptoms in military personnel with combat experience

Public health financing as a driver of economic growth and equity: Evidence from Morocco

Functional (dissociative) seizures in PCDH19 ‐clustering epilepsy: Clinical characteristics and diagnostic challenges

The characteristic analysis and pattern classification of Beijing’s commercial districts based on multi-source geographical big data

ARTIFICIAL INTELLIGENCE-ENABLED REGTECH FOR KYC, FINANCIAL COMPLIANCE, AND REGULATORY REPORTING: APPLICATIONS, RISKS, AND FUTURE DIRECTIONS

Agreement Between Six-Minute Walk Test-Based Equations and Bruce-Derived Aerobic-Fitness Estimates in Adults with Metabolic Syndrome: A Single-City Cross-Sectional Method-Comparison Study

Analysis of gut microbiota and fecal/plasma short-chain fatty acids in non-dialysis renal anemia patients: associations with clinical parameters

Development and internal validation of a simple EMS-based clinical score for predicting 24-hour mortality among older adult trauma patients: a retrospective single-centre cohort study

First molecularly characterized Para‐Bombay phenotype in Iraq: Clinical, serological and genetic insights with implications for transfusion safety

Factores de Éxito y Barreras Institucionales en la Adopción de la Teleenfermería y la Salud Digital: Una Revisión Sistemática

Clinical Characteristics and Early Outcomes of Acute Pulmonary Embolism Presenting with Syncope

Startup ecosystem of Albergo Diffuso: digital orchestration of value co-creation

Gamification in digital branding

Formation of a Unified Alphabet of Ancient Turkic Dialects for Image Annotation

Hyperbaric Oxygen Therapy in Sinonasal Disease: A Narrative Review of Mechanisms, Clinical Evidence, and Multidisciplinary Perspectives on Invasive Fungal Rhinosinusitis and Post-Radiotherapy Injury

Acute caffeine and 30-m sprint performance in female collegiate team-sport athletes: a preliminary, exploratory crossover trial

Catheter-Based Renal Denervation in Uncontrolled and Resistant Hypertension: Evidence, Guidelines, Special Populations and Clinical Implementation

Kidney transplant program at the Chelyabinsk Regional Clinical Hospital

Influence of Healthcare Workers' Knowledge in Addressing Mental Health Issues in the Provision of Holistic Care at Mombasa Hospital

MicroRNA ‐Mediated Autophagy and Cardiovascular Diseases: Exploring the Crossroads of Atherosclerosis and Beyond

Geospatial Assessment of Spatial Distribution and Accessibility of Primary Health Care Centres in Abuja Municipal Area Council, Federal Capital Territory, Nigeria

The Antidepressant Effects of the mGlu2/3 Receptor Antagonist TS-161 in Treatment-Resistant Depression

Impact of Artificial Intelligence and Technology on Labour Relations